Citation Impact
Citing Papers
Genetically Encoding Fluorosulfate- l -tyrosine To React with Lysine, Histidine, and Tyrosine via SuFEx in Proteins in Vivo
2018
SuFEx-enabled, agnostic discovery of covalent inhibitors of human neutrophil elastase
2019 StandoutNobel
IRE1 Signaling Affects Cell Fate During the Unfolded Protein Response
2007 Science
Sulfur [ 18 F]Fluoride Exchange Click Chemistry Enabled Ultrafast Late-Stage Radiosynthesis
2021 StandoutNobel
Signal integration in the endoplasmic reticulum unfolded protein response
2007 Standout
Phosphorylation of eIF2 Facilitates Ribosomal Bypass of an Inhibitory Upstream ORF to Enhance CHOP Translation
2011
Endoplasmic reticulum stress responses
2007
Mechanisms, regulation and functions of the unfolded protein response
2020 Standout
Short-Term Effects of Nose-Only Cigarette Smoke Exposure on Glutathione Redox Homeostasis, Cytochrome P450 1A1/2 and Respiratory Enzyme Activities in Mice Tissues
2013 Standout
Surface functionalization of quantum dots for biological applications
2014
Lipopolysaccharide Induces Autophagic Cell Death through the PERK-Dependent Branch of the Unfolded Protein Response in Human Alveolar Epithelial A549 Cells
2015
A PGC1-α-dependent myokine that drives brown-fat-like development of white fat and thermogenesis
2012 StandoutNature
Transcriptional Repression of ATF4 Gene by CCAAT/Enhancer-binding Protein β (C/EBPβ) Differentially Regulates Integrated Stress Response
2012
Autophagy and the Integrated Stress Response
2010 Standout
An essential role for XBP-1 in host protection against immune activation in C. elegans
2010 Nature
Hallmarks of aging: An expanding universe
2023 Standout
Pfam: the protein families database
2013 Standout
Cigarette Smoke Induces an Unfolded Protein Response in the Human Lung
2007
Macrophages in the Pathogenesis of Atherosclerosis
2011 Standout
The unfolded protein response: controlling cell fate decisions under ER stress and beyond
2012 Standout
Treatment of Obesity with Celastrol
2015 Standout
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Sec24p and Sec16p cooperate to regulate the GTP cycle of the COPII coat
2011 StandoutNobel
The Unfolded Protein Response Mediates Adaptation to Exercise in Skeletal Muscle through a PGC-1α/ATF6α Complex
2011
Effects of extracellular matrix viscoelasticity on cellular behaviour
2020 StandoutNature
Endoplasmic Reticulum Stress Markers Are Associated with Obesity in Nondiabetic Subjects
2008
Integrating single-cell transcriptomic data across different conditions, technologies, and species
2018 Standout
Mitochondria: In Sickness and in Health
2012 Standout
That which does not kill me makes me stronger: adapting to chronic ER stress
2007
Endoplasmic Reticulum Stress, Pancreatic -Cell Degeneration, and Diabetes
2012
Two to Tango: Regulation of Mammalian Iron Metabolism
2010 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
NOD1 and NOD2 signalling links ER stress with inflammation
2016 StandoutNature
Intrinsically disordered proteins: regulation and disease
2011
ATF6α Optimizes Long-Term Endoplasmic Reticulum Function to Protect Cells from Chronic Stress
2007
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
From endoplasmic-reticulum stress to the inflammatory response
2008 StandoutNature
Dephosphorylation of Translation Initiation Factor 2α Enhances Glucose Tolerance and Attenuates Hepatosteatosis in Mice
2008
Both Transcriptional Regulation and Translational Control of ATF4 Are Central to the Integrated Stress Response
2010
A mathematical model of the unfolded protein stress response reveals the decision mechanism for recovery, adaptation and apoptosis
2013
Endoplasmic reticulum stress and pancreatic β-cell death
2011
Proteinuria and Hyperglycemia Induce Endoplasmic Reticulum Stress
2008
Induction of Diabetes in Aged C57B6 Mice Results in Severe Nephropathy
2010
ER-stress-induced transcriptional regulation increases protein synthesis leading to cell death
2013
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
UPR Pathways Combine to Prevent Hepatic Steatosis Caused by ER Stress-Mediated Suppression of Transcriptional Master Regulators
2008
XBP1 Links ER Stress to Intestinal Inflammation and Confers Genetic Risk for Human Inflammatory Bowel Disease
2008 Standout
Integrating the mechanisms of apoptosis induced by endoplasmic reticulum stress
2011 Standout
Chop deletion reduces oxidative stress, improves β cell function, and promotes cell survival in multiple mouse models of diabetes
2008
ER Stress-Inducible Factor CHOP Affects the Expression of Hepcidin by Modulating C/EBPalpha Activity
2009
Hydrogels with tunable stress relaxation regulate stem cell fate and activity
2015 Standout
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Ribosome Elongation Stall Directs Gene-specific Translation in the Integrated Stress Response
2016
Fine-Tuning of the Unfolded Protein Response: Assembling the IRE1α Interactome
2009
Protein misfolding in the endoplasmic reticulum as a conduit to human disease
2016 Nature
Proteostasis control by the unfolded protein response
2015
Divergent Effects of PERK and IRE1 Signaling on Cell Viability
2009
Modulating the integrated stress response to slow aging and ameliorate age-related pathology
2021
Targeting ER stress induced apoptosis and inflammation in cancer
2010
Immunogenic cell death and DAMPs in cancer therapy
2012 Standout
Modeling neurodevelopmental disorder-associated humanAGO1mutations inCaenorhabditis elegansArgonautealg-1
2024 StandoutNobel
Influenza Induces Endoplasmic Reticulum Stress, Caspase-12–Dependent Apoptosis, and c-Jun N-Terminal Kinase–Mediated Transforming Growth Factor–β Release in Lung Epithelial Cells
2011
Inhibition of Eukaryotic Initiation Factor 2 Alpha Phosphatase Reduces Tissue Damage and Improves Learning and Memory after Experimental Traumatic Brain Injury
2015
The integrated stress response
2016 Standout
Endoplasmic Reticulum Stress and Oxidative Stress in Cell Fate Decision and Human Disease
2014
Translational Control and the Unfolded Protein Response
2007
Endoplasmic Reticulum Stress and Oxidative Stress: A Vicious Cycle or a Double-Edged Sword?
2007
Biophysically Defined and Cytocompatible Covalently Adaptable Networks as Viscoelastic 3D Cell Culture Systems
2013
Enzyme stabilization via computationally guided protein stapling
2017
The Unfolded Protein Response: A Pathway That Links Insulin Demand with β-Cell Failure and Diabetes
2008
Resetting translational homeostasis restores myelination in Charcot-Marie-Tooth disease type 1B mice
2013
Improving Protein Expression, Stability, and Function with ProteinMPNN
2024 StandoutNobel
Mice deficient in LMAN1 exhibit FV and FVIII deficiencies and liver accumulation of α1-antitrypsin
2011 StandoutNobel
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
BiP Availability Distinguishes States of Homeostasis and Stress in the Endoplasmic Reticulum of Living Cells
2010
Playing with the Molecules of Life
2018
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
Endoplasmic Reticulum Stress in Immunity
2014
Tuning Enzyme Thermostability via Computationally Guided Covalent Stapling and Structural Basis of Enhanced Stabilization
2022
Translational and posttranslational regulation of XIAP by eIF2α and ATF4 promotes ER stress–induced cell death during the unfolded protein response
2014
Endoplasmic Reticulum Homeostasis Is Modulated by the Forkhead Transcription Factor FKH-9 During Infection of Caenorhabditis elegans
2018 StandoutNobel
Regulation of basal cellular physiology by the homeostatic unfolded protein response
2010
CHOP induces activating transcription factor 5 (ATF5) to trigger apoptosis in response to perturbations in protein homeostasis
2013
The Unfolded Protein Response: From Stress Pathway to Homeostatic Regulation
2011 StandoutScience
Tight Regulation of Unstructured Proteins: From Transcript Synthesis to Protein Degradation
2008 Science
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Function of IRE1 alpha in the placenta is essential for placental development and embryonic viability
2009 StandoutNobel
Ppp1r15 gene knockout reveals an essential role for translation initiation factor 2 alpha (eIF2α) dephosphorylation in mammalian development
2009
Disease Tolerance as a Defense Strategy
2012 StandoutScience
Adapting Proteostasis for Disease Intervention
2008 StandoutScience
Selective mRNA translation during eIF2 phosphorylation induces expression of IBTKα
2014
Mechanisms of Diabetic Complications
2013 Standout
Endoplasmic Reticulum Stress Regulates Adipocyte Resistin Expression
2009
Increased Susceptibility to DNA Virus Infection in Mice with a GCN2 Mutation
2011 StandoutNobel
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
Enhanced sensitivity to DSS colitis caused by a hypomorphic Mbtps1 mutation disrupting the ATF6-driven unfolded protein response
2009 StandoutNobel
Cellular uptake of nanoparticles: journey inside the cell
2017 Standout
Enhancing Protein Stability with Genetically Encoded Noncanonical Amino Acids
2018
Mitophagy confers resistance to siderophore-mediated killing by Pseudomonas aeruginosa
2015 StandoutNobel
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry
2020 StandoutNobel
Grp78 Heterozygosity Promotes Adaptive Unfolded Protein Response and Attenuates Diet-Induced Obesity and Insulin Resistance
2009
Caenorhabditis elegans responses to bacteria from its natural habitats
2016 StandoutNobel
Caenorhabditis elegans microRNAs of the let-7 family act in innate immune response circuits and confer robust developmental timing against pathogen stress
2015 StandoutNobel
Works of Jack Li being referenced
Adaptation to ER Stress Is Mediated by Differential Stabilities of Pro-Survival and Pro-Apoptotic mRNAs and Proteins
2006
Aromatic Aldehyde and Hydrazine Activated Peptide Coated Quantum Dots for Easy Bioconjugation and Live Cell Imaging
2011
Enhancing protein stability with extended disulfide bonds
2016
Genetic Incorporation of a Reactive Isothiocyanate Group into Proteins
2016