Standout Papers
Citation Impact
Citing Papers
Visualizing enveloping layer glycans during zebrafish early embryogenesis
2010 StandoutNobel
Rapid protein fold determination using unassigned NMR data
2003 StandoutNobel
Targeted Anti–Vascular Endothelial Growth Factor Receptor-2 Therapy Leads to Short-term and Long-term Impairment of Vascular Function and Increase in Tumor Hypoxia
2006
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Antiangiogenic Therapy Elicits Malignant Progression of Tumors to Increased Local Invasion and Distant Metastasis
2009 Standout
Bioorthogonal Chemistry: Fishing for Selectivity in a Sea of Functionality
2009 StandoutNobel
Proton NMR studies of human C3a anaphylatoxin in solution: sequential resonance assignments, secondary structure, and global fold
1988
Autonomous protein folding units
2000
Tumor-Associated Macrophages in Breast Cancer
2002
Targeting HIF-1 for cancer therapy
2003 StandoutNobel
Time-saving methods for heteronuclear multidimensional NMR of (13C, 15N) doubly labeled proteins
1994
The cancer glycocalyx mechanically primes integrin-mediated growth and survival
2014 StandoutNatureNobel
A two‐dimensional 1H NMR study on Megasphaera elsdenii flavodoxin in the reduced state
1990
Involvement of endothelial progenitor cells in tumor vascularization
2010
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
LDL receptor-related protein, a multifunctional ApoE receptor, binds secreted β-amyloid precursor protein and mediates its degradation
1995
A New Weapon for Attacking Tumor Blood Vessels
2008 StandoutNobel
Lessons from phase III clinical trials on anti-VEGF therapy for cancer
2006
Anti-angiogenic Chemotherapy in Central Nervous System Tumors
2004
Thrombospondins: from structure to therapeutics
2008
uPAR: a versatile signalling orchestrator
2002
Thrombospondin‐1 as an endogenous inhibitor of angiogenesis and tumor growth
2002
Corrupt policemen: inflammatory cells promote tumor angiogenesis
2008
Relationship between nuclear magnetic resonance chemical shift and protein secondary structure
1991 Standout
Translation of new cancer treatments from pet dogs to humans
2008 Standout
The multifaceted circulating endothelial cell in cancer: towards marker and target identification
2006
Binding and displacement of vascular endothelial growth factor (VEGF) by thrombospondin: Effect on human microvascular endothelial cell proliferation and angiogenesis
1999
Regulation of Notch Signaling by O-Linked Fucose
2002
Metastasis to bone: causes, consequences and therapeutic opportunities
2002 Standout
Mechanisms of Bone Metastasis
2004 Standout
Vascular Endothelial Growth Factor Increases Urokinase Receptor Expression in Vascular Endothelial Cells
1995
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
The anti-angiogenic basis of metronomic chemotherapy
2004 Standout
Stimulatory effect of unsaturated fatty acids on the level of plasminogen activator inhibitor‐1 mRNA in cultured human endothelial cells
1995 StandoutNobel
Predicting benefit from anti-angiogenic agents in malignancy
2006
Molecular mechanisms and clinical applications of angiogenesis
2011 StandoutNature
Angiogenesis as a therapeutic target
2005 StandoutNature
Tumor Angiogenesis
2008 Standout
Soluble CD36 Ectodomain Binds Negatively Charged Diacylglycerol Ligands and Acts as a Co-Receptor for TLR2
2009 StandoutNobel
Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
2010 StandoutNobel
Dual Roles of Cripto as a Ligand and Coreceptor in the Nodal Signaling Pathway
2002
Transverse relaxation-optimized NMR spectroscopy with the outer membrane protein OmpX in dihexanoyl phosphatidylcholine micelles
2001 StandoutNobel
A segment of cold shock protein directs the folding of a combinatorial protein
2005 StandoutNobel
In Vivo Imaging of Membrane-Associated Glycans in Developing Zebrafish
2008 StandoutScienceNobel
Leukocyte lipid body formation and eicosanoid generation: cyclooxygenase-independent inhibition by aspirin.
1996 StandoutNobel
Pten and p27KIP1 cooperate in prostate cancer tumor suppression in the mouse
2001
Regulation of the endothelial cell urokinase-type plasminogen activator receptor. Evidence for cyclic AMP-dependent and protein kinase C-dependent pathways.
1993 StandoutNobel
Functional rafts in cell membranes
1997 StandoutNature
Effects of Aging and Hypoxia-Inducible Factor-1 Activity on Angiogenic Cell Mobilization and Recovery of Perfusion After Limb Ischemia
2007 StandoutNobel
Circulating endothelial-cell kinetics and viability predict survival in breast cancer patients receiving metronomic chemotherapy
2006
Ligand-induced prostaglandin synthesis requires expression of the TIS10/PGS-2 prostaglandin synthase gene in murine fibroblasts and macrophages.
1994
Proposed three-dimensional structure for the cellular prion protein.
1994 StandoutNobel
Topological distribution of four-alpha-helix bundles.
1989
Thrombospondin 1, a mediator of the antiangiogenic effects of low-dose metronomic chemotherapy
2003
Bacterial Biofilms: A Common Cause of Persistent Infections
1999 StandoutScience
The cell-adhesion G protein-coupled receptor BAI3 is a high-affinity receptor for C1q-like proteins
2011 StandoutNobel
Blood-Based Biomarkers of SU11248 Activity and Clinical Outcome in Patients with Metastatic Imatinib-Resistant Gastrointestinal Stromal Tumor
2007
Antiangiogenic Therapy: A Universal Chemosensitization Strategy for Cancer?
2006 Science
Crystal structure of the TSP-1 type 1 repeats
2002
Role of Glycosylation in Development
2004
α-Proton chemical shifts and secondary structure in proteins
1989
Expanding the Genetic Repertoire of the Methylotrophic Yeast Pichia pastoris
2009
The biology , function , and biomedical applications of exosomes
2020 StandoutScience
Potential of preventing Pseudomonas aeruginosa lung infections in cystic fibrosis patients: Experimental studies in animals
1996
Endocytosis of urokinase-plasminogen activator inhibitor type 1 complexes bound to a chimeric transmembrane urokinase receptor.
1994 StandoutNobel
Therapy-Induced Acute Recruitment of Circulating Endothelial Progenitor Cells to Tumors
2006 Science
Cooperativity of Nkx3.1 and Pten loss of function in a mouse model of prostate carcinogenesis
2002
A Comparative Analysis of Low-Dose Metronomic Cyclophosphamide Reveals Absent or Low-Grade Toxicity on Tissues Highly Sensitive to the Toxic Effects of Maximum Tolerated Dose Regimens
2004
Solution structure of a 142-residue recombinant prion protein corresponding to the infectious fragment of the scrapie isoform
1997 StandoutNobel
Isotope exchange probes and enzyme mechanisms
1978 StandoutNobel
Cancer Genome Landscapes
2013 StandoutScience
Reduction of vascular and permeable regions in solid tumors detected by macromolecular contrast magnetic resonance imaging after treatment with antiangiogenic agent TNP-470.
2003
Angiogenesis
2006
Structure of the recombinant full-length hamster prion protein PrP(29–231): The N terminus is highly flexible
1997 StandoutNobel
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells
2012 StandoutNobel
Anticancer Therapies Combining Antiangiogenic and Tumor Cell Cytotoxic Effects Reduce the Tumor Stem-Like Cell Fraction in Glioma Xenograft Tumors
2007
Normalization of Tumor Vasculature: An Emerging Concept in Antiangiogenic Therapy
2005 StandoutScience
Imaging the glycome
2008 StandoutNobel
Synergistic effect of HIF-1α gene therapy and HIF-1-activated bone marrow-derived angiogenic cells in a mouse model of limb ischemia
2009 StandoutNobel
Adenoviral transfer of HIF-1α enhances vascular responses to critical limb ischemia in diabetic mice
2009 StandoutNobel
Endothelial cells in physiology and in the pathophysiology of vascular disorders.
1998 Standout
Fucose: biosynthesis and biological function in mammals
2003
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Regions involved in binding of urokinase-type-1 inhibitor complex and pro-urokinase to the endocytic alpha 2-macroglobulin receptor/low density lipoprotein receptor-related protein. Evidence that the urokinase receptor protects pro-urokinase against binding to the endocytic receptor.
1994
Identification of proangiogenic TIE2-expressing monocytes (TEMs) in human peripheral blood and cancer
2007
Hypoxia-inducible factor 1 is required for remote ischemic preconditioning of the heart
2013 StandoutNobel
Early onset of neoplasia in the prostate and skin of mice with tissue-specific deletion of Pten
2004 StandoutNobel
Pathologic progression of autochthonous prostate cancer in the TRAMP model
1999
NMR structure of the calreticulin P-domain
2001 StandoutNobel
Chemical Glycoproteomics
2016 StandoutNobel
The chemical shift index: a fast and simple method for the assignment of protein secondary structure through NMR spectroscopy
1992 Standout
Optimal biologic dose of metronomic chemotherapy regimens is associated with maximum antiangiogenic activity
2005
Works of Jack Henkin being referenced
Cooperative Activity of Cytotoxic Chemotherapy with Antiangiogenic Thrombospondin-I Peptides, ABT-526 in Pet Dogs with Relapsed Lymphoma
2006
Thrombospondin-1 Peptide ABT-510 Combined with Valproic Acid Is an Effective Antiangiogenesis Strategy in Neuroblastoma
2007
Pre-metastatic cancer exosomes induce immune surveillance by patrolling monocytes at the metastatic niche
2017
Embryonic Fibroblasts That Are Genetically Deficient in Low Density Lipoprotein Receptor-related Protein Demonstrate Increased Activity of the Urokinase Receptor System and Accelerated Migration on Vitronectin
1997
Genetic heterogeneity of the vasculogenic phenotype parallels angiogenesis
2005
Three Distinct d-Amino Acid Substitutions Confer Potent Antiangiogenic Activity on an Inactive Peptide Derived from a Thrombospondin-1 Type 1 Repeat
1999
An amino-terminal fragment of urokinase isolated from a prostate cancer cell line (PC-3) is mitogenic for osteoblast-like cells
1990
Comparison of model and nuclear magnetic resonance structures for the human inflammatory protein C5a
1988
Inhibition of tumor growth by systemic treatment with thrombospondin‐1 peptide mimetics
2002
Sequence-specific assignments in the proton NMR spectrum of the human inflammatory protein C5a
1988
Exogenous rh-urokinase modifies inflammation and Pseudomonas aeruginosa infection in a rat chronic pulmonary infection model
1993
Workgroup 3: Transgenic and reconstitution models of prostate cancer
1998
Paclitaxel at ultra low concentrations inhibits angiogenesis without affecting cellular microtubule assembly
2003
Prevention of breast cancer growth, invasion, and metastasis by antiestrogen tamoxifen alone or in combination with urokinase inhibitor B-428.
1997
Three Distinct d-Amino Acid Substitutions Confer Potent Antiangiogenic Activity on an Inactive Peptide Derived from a Thrombospondin-1 Type 1 Repeat
1999
Selective inhibition of endothelial cell proliferation by fumagillin is not due to differential expression of methionine aminopeptidases
2000
Preclinical Evaluation of Antiangiogenic Thrombospondin-1 Peptide Mimetics, ABT-526 and ABT-510, in Companion Dogs with Naturally Occurring Cancers
2006
Low density lipoprotein receptor-related protein/alpha 2-macroglobulin receptor mediates cellular uptake of pro-urokinase.
1993
Single-chain urokinase-type plasminogen activator bound to its receptor is relatively resistant to plasminogen activator inhibitor type 1
1996
Interaction of single-chain urokinase-type plasminogen activator with human endothelial cells.
1990 StandoutNobel
Evidence against an acyl-enzyme intermediate in the reaction catalyzed by clostridial phosphotransacetylase
1976
Domain structure and interactions of recombinant urokinase-type plasminogen activator.
1992
Structural requirements for the growth factor activity of the amino-terminal domain of urokinase.
1992