Citation Impact
Citing Papers
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Alternative Zippering as an On-Off Switch for SNARE-Mediated Fusion
2009 StandoutScienceNobel
Complexin Controls the Force Transfer from SNARE Complexes to Membranes in Fusion
2009 StandoutScienceNobel
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Conformational Switch of Syntaxin-1 Controls Synaptic Vesicle Fusion
2008 StandoutScienceNobel
Computational Thermostabilization of an Enzyme
2005 StandoutScienceNobel
Distinct Populations of Primary and Secondary Effectors During RNAi in C. elegans
2006 StandoutScienceNobel
Munc18-1 binds directly to the neuronal SNARE complex
2007 StandoutNobel
A two stage click-based library of protein tyrosine phosphatase inhibitors
2006
The Phosphotyrosine Phosphatase PTP1D, but not PTP1C, Is an Essential Mediator of Fibroblast Proliferation Induced by Tyrosine Kinase and G Protein-coupled Receptors
1995
Structural insight into the PTS sugar transporter EIIC
2014
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
The type III needle and the damage done
2005
Reversible Inactivation of Protein-tyrosine Phosphatase 1B in A431 Cells Stimulated with Epidermal Growth Factor
1998
Insights into Substrate Binding and Catalytic Mechanism of Human Tyrosyl-DNA Phosphodiesterase (Tdp1) from Vanadate and Tungstate-inhibited Structures
2002
Vam3p structure reveals conserved and divergent properties of syntaxins.
2001
Multiple SNARE interactions of an SM protein: Sed5p/Sly1p binding is dispensable for transport
2004
The X-ray Crystal Structures of Yersinia Tyrosine Phosphatase with Bound Tungstate and Nitrate
1996
A conformational switch in syntaxin during exocytosis: role of munc18
1999
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
Recognition and specificity in protein tyrosine kinase-mediated signalling
1995
Revealing mechanisms for SH2 domain mediated regulation of the protein tyrosine phosphatase SHP-2
1998
Pore loops: An emerging theme in ion channel structure
1995 StandoutNobel
Characterization of the Interactions between PDZ Domains of the Protein-tyrosine Phosphatase PTPL1 and the Carboxyl-terminal Tail of Fas
1997
Structure, mechanism, and evolution of the mRNA capping apparatus
2000
How Tlg2p/syntaxin 16 'snares' Vps45
2002
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Negative Regulation of PKB/Akt-Dependent Cell Survival by the Tumor Suppressor PTEN
1998 StandoutNobel
Membrane Fusion
2003 StandoutNobel
Purified Argonaute2 and an siRNA form recombinant human RISC
2005
Beyond LDL oxidation: ROS in vascular signal transduction
2003
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
The bacterial injection kit: Type III secretion systems
2005
Sly1 Binds to Golgi and ER Syntaxins via a Conserved N-Terminal Peptide Motif
2002 StandoutNobel
Crystal Structure of a Transition State Mimic for Tdp1 Assembled from Vanadate, DNA, and a Topoisomerase I-Derived Peptide
2003
Reversible Oxidation and Inactivation of Protein Tyrosine Phosphatases In Vivo
2002
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
Long-Term Potentiation Is Reduced in Mice That Are Doubly Mutant in Endothelial and Neuronal Nitric Oxide Synthase
1996 StandoutNobel
Protein tyrosine phosphatases take off
1995
Nucleases: diversity of structure, function and mechanism
2010
Two distinct RNase activities of CRISPR-C2c2 enable guide-RNA processing and RNA detection
2016 StandoutNatureNobel
Dual Modes of Munc18-1/SNARE Interactions Are Coupled by Functionally Critical Binding to Syntaxin-1 N Terminus
2007 StandoutNobel
Energetics of nucleophile activation in a protein tyrosine phosphatase
1997
Three-Dimensional Structure of the Complexin/SNARE Complex
2002 StandoutNobel
Selective Activation of Cognate SNAREpins by Sec1/Munc18 Proteins
2007 StandoutNobel
A Complexin/Synaptotagmin 1 Switch Controls Fast Synaptic Vesicle Exocytosis
2006 StandoutNobel
Prediction of the structure of symmetrical protein assemblies
2007 StandoutNobel
Dynamical Contributions to Enzyme Catalysis: Critical Tests of A Popular Hypothesis
2006 StandoutNobel
Ketosteroid isomerase provides further support for the idea that enzymes work by electrostatic preorganization
2010 StandoutNobel
Imaging single membrane fusion events mediated by SNARE proteins
2004 StandoutNobel
SNAREpin/Munc18 promotes adhesion and fusion of large vesicles to giant membranes
2008 StandoutNobel
Signaling Through Scaffold, Anchoring, and Adaptor Proteins
1997 StandoutScience
Testing Geometrical Discrimination within an Enzyme Active Site: Constrained Hydrogen Bonding in the Ketosteroid Isomerase Oxyanion Hole
2008
Three-Dimensional Structure of an Independently Folded Extracellular Domain of Human Amyloid-β Precursor Protein,
2004 StandoutNobel
A bacterial Argonaute with noncanonical guide RNA specificity
2016 StandoutNobel
G protein beta gamma subunits stimulate phosphorylation of Shc adapter protein.
1995 StandoutNobel
Orchestrating Redox Signaling Networks through Regulatory Cysteine Switches
2009
Crystal Structure of the RIM1α C2B Domain at 1.7 Å Resolution,
2007 StandoutNobel
Crystal Structure of Human Protein Tyrosine Phosphatase 1B
1994 Science
In vitro reconstitution of the human RISC-loading complex
2008 StandoutNobel
Inflammation and autoimmunity caused by a SHP1 mutation depend on IL-1, MyD88, and a microbial trigger
2008 StandoutNobel
Growth suppression of glioma cells by PTEN requires a functional phosphatase catalytic domain
1997
Crystal Structure of the PTEN Tumor Suppressor
1999
DNA origami protection and molecular interfacing through engineered sequence-defined peptoids
2020 StandoutNobel
Rational Tuning of Fluorobenzene Probes for Cysteine‐Selective Protein Modification
2018 StandoutNobel
The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds
2004 Standout
P-TEN, the tumor suppressor from human chromosome 10q23, is a dual-specificity phosphatase
1997
Anatomy and Dynamics of a Supramolecular Membrane Protein Cluster
2007 StandoutScienceNobel
E-Syts, a family of membranous Ca 2+ -sensor proteins with multiple C 2 domains
2007 StandoutNobel
Walden-Inversion-Enforced Transition-State Stabilization in a Protein Tyrosine Phosphatase
1998
Endothelial nitric oxide synthase localized to hippocampal pyramidal cells: implications for synaptic plasticity.
1994
Endothelial NOS and the Blockade of LTP by NOS Inhibitors in Mice Lacking Neuronal NOS
1994 StandoutScienceNobel
Crystal Structure of the Dual Specificity Protein Phosphatase VHR
1996 Science
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Dissecting the catalytic mechanism of protein-tyrosinephosphatases.
1994
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
Membrane Fusion: Grappling with SNARE and SM Proteins
2009 StandoutScienceNobel
The Role of Dynamics in Enzyme Activity
2003
Enzyme millisecond conformational dynamics do not catalyze the chemical step
2009 StandoutNobel
Functional dynamics in the active site of the ribonuclease binase
2001
Mechanisms of signaling and related enzymes
1997
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Structural Basis of Transcription: RNA Polymerase II at 2.8 Ångstrom Resolution
2001 StandoutScienceNobel
Mechanisms of signaling and related enzymes
1997
A C-terminal motif found in the β 2 -adrenergic receptor, P2Y1 receptor and cystic fibrosis transmembrane conductance regulator determines binding to the Na + /H + exchanger regulatory factor family of PDZ proteins
1998 StandoutNobel
Tyrosine phosphorylation of an SH2-containing protein tyrosine phosphatase is coupled to platelet thrombin receptor via a pertussis toxin-sensitive heterotrimeric G-protein.
1995
Visualization of intermediate and transition-state structures in protein-tyrosine phosphatase catalysis.
1996
Works of Jack E. Dixon being referenced
‘Zip codes’ direct intracellular protein tyrosine phosphatases to the correct cellular ‘address’
1994
The Cys(X)5Arg Catalytic Motif in Phosphoester Hydrolysis
1994
New vectors for high level expression of recombinant proteins in bacteria
1992
Crystal structure of Yersinia protein tyrosine phosphatase at 2.5 Å and the complex with tungstate
1994 Nature
Active site labeling of the Yersinia protein tyrosine phosphatase: The determination of the pKa of the active site cysteine and the function of the conserved histidine 402
1993
1999