Citation Impact
Citing Papers
Disruption of MyD88 signaling suppresses hemophagocytic lymphohistiocytosis in mice
2011 StandoutNobel
Hypomorphic mutations in PRF1, MUNC13-4, and STXBP2 are associated with adult-onset familial HLH
2011
PD-1 + regulatory T cells amplified by PD-1 blockade promote hyperprogression of cancer
2019 StandoutNobel
PD-L1 regulates the development, maintenance, and function of induced regulatory T cells
2009 Standout
Clinical Practice Guidelines for Clostridium difficile Infection in Adults and Children: 2017 Update by the Infectious Diseases Society of America (IDSA) and Society for Healthcare Epidemiology of America (SHEA)
2017 Standout
Autoimmune lymphoproliferative syndrome: molecular basis of disease and clinical phenotype
2006
FoxP3+ T regulatory cells in cancer: Prognostic biomarkers and therapeutic targets
2020
Immunosenescence and human vaccine immune responses
2019
Regulatory T cells in tumor microenvironment: new mechanisms, potential therapeutic strategies and future prospects
2020
Tregopathies: Monogenic diseases resulting in regulatory T-cell deficiency
2018
Chimeric Antigen Receptor–Modified T Cells for Acute Lymphoid Leukemia
2013 Standout
Caspases at the crossroads of immune-cell life and death
2006
Regulatory T cells exert checks and balances on self tolerance and autoimmunity
2009 StandoutNobel
The multifaceted role of Fas signaling in immune cell homeostasis and autoimmunity
2000
Hemophagocytic lymphohistiocytosis
2011
Locating and classifying fluorescent tags behind turbid layers using time-resolved inversion
2015 StandoutNobel
Human regulatory T cells: role in autoimmune disease and therapeutic opportunities
2008
The emerging role of lncRNAs in cancer
2015 Standout
Deficiency in activation-induced cytidine deaminase promotes systemic autoimmunity inlprmice on a C57BL/6 background
2009
Juvenile idiopathic arthritis
2007 Standout
Repeated TLR9 stimulation results in macrophage activation syndrome–like disease in mice
2011
Genome-wide association study and meta-analysis find that over 40 loci affect risk of type 1 diabetes
2009 Standout
The Receptor Ly108 Functions as a SAP Adaptor-Dependent On-Off Switch for T Cell Help to B Cells and NKT Cell Development
2012
Tolerance and Autoimmunity: Lessons at the Bedside of Primary Immunodeficiencies
2007
Diagnosis, management, and treatment of hepatitis C: An update # † ‡
2008 Standout
Distinct cytokine profiles of systemic-onset juvenile idiopathic arthritis-associated macrophage activation syndrome with particular emphasis on the role of interleukin-18 in its pathogenesis
2010
Type 2 diabetes as an inflammatory disease
2011 Standout
Biological Functions of Autophagy Genes: A Disease Perspective
2019 Standout
mRNA vaccines for infectious diseases: principles, delivery and clinical translation
2021 StandoutNobel
Pharmacological modulation of autophagy: therapeutic potential and persisting obstacles
2017
Functional Delineation and Differentiation Dynamics of Human CD4+ T Cells Expressing the FoxP3 Transcription Factor
2009 StandoutNobel
Antithrombotic Therapy for VTE Disease
2012 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Type I IFN response associated with mTOR activation in the TAFRO subtype of idiopathic multicentric Castleman disease
2020
Positive and Negative Signaling through SLAM Receptors Regulate Synapse Organization and Thresholds of Cytolysis
2012
Experience With Hemophagocytic Lymphohistiocytosis/Macrophage Activation Syndrome at a Single Institution
2009
Regulatory T Cells Control Antigen-Specific Expansion of Tfh Cell Number and Humoral Immune Responses via the Coreceptor CTLA-4
2014 StandoutNobel
Regulatory T Cells: Molecular and Cellular Basis for Immunoregulation
2017
Molecular mechanisms of T cell co-stimulation and co-inhibition
2013 Standout
Systemic JIA: new developments in the understanding of the pathophysiology and therapy
2009
Type 1 diabetes
2013 Standout
Adult haemophagocytic syndrome
2013
Sickle-cell disease
2010 Standout
The Transcription Factor Foxp3 Shapes Regulatory T Cell Identity by Tuning the Activity of trans-Acting Intermediaries
2020
Cancer immunotherapy comes of age
2011 StandoutNature
Regulatory T-cell immunotherapy for tolerance to self antigens and alloantigens in humans
2007
Pathological inflammation in patients with COVID-19: a key role for monocytes and macrophages
2020 Standout
Deletion of PD-1 destabilizes the lineage identity and metabolic fitness of tumor-infiltrating regulatory T cells
2022
Pyroptosis: host cell death and inflammation
2009 Standout
Defining roles of specific reactive oxygen species (ROS) in cell biology and physiology
2022 Standout
Macrophage activation syndrome in patients with systemic juvenile idiopathic arthritis is associated with MUNC13‐4 polymorphisms
2008
Targeting ferroptosis as a vulnerability in cancer
2022 Standout
COVID-19: consider cytokine storm syndromes and immunosuppression
2020 Standout
Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
2024 StandoutNobel
The genetics of macrophage activation syndrome
2020
The Immunology of Macrophage Activation Syndrome
2019
Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome
2015
Chimeric Antigen Receptor T Cells for Sustained Remissions in Leukemia
2014 Standout
Different brands of intravenous immunoglobulin for primary immunodeficiencies: how to choose the best option for the patient?
2015
The TNF and TNF Receptor Superfamilies
2001 Standout
Diagnosis, Treatment, and Long-Term Management of Kawasaki Disease: A Scientific Statement for Health Professionals From the American Heart Association
2017 Standout
Targeting non-coding RNAs with the CRISPR/Cas9 system in human cell lines
2014
A guide to cancer immunotherapy: from T cell basic science to clinical practice
2020 Standout
Large-scale genetic fine mapping and genotype-phenotype associations implicate polymorphism in the IL2RA region in type 1 diabetes
2007
The gut microbiota shapes intestinal immune responses during health and disease
2009 Standout
Tumor-infiltrating regulatory T cells as targets of cancer immunotherapy
2023 StandoutNobel
Nonmyeloablative HLA-Matched Sibling Allogeneic Hematopoietic Stem Cell Transplantation for Severe Sickle Cell Phenotype
2014
Utility of Humanized BLT Mice for Analysis of Dengue Virus Infection and Antiviral Drug Testing
2013 StandoutNobel
CD4+CD25−LAG3+regulatory T cells controlled by the transcription factor Egr-2
2009 StandoutNobel
Biochemical and Genetic Evidence for a SAP-PKC-θ Interaction Contributing to IL-4 Regulation
2010
Regulatory T Cells and Human Disease
2020 StandoutNobel
Apoptosis: A Review of Programmed Cell Death
2007 Standout
Follicular Helper CD4 T Cells (TFH)
2011 Standout
CD45: A Critical Regulator of Signaling Thresholds in Immune Cells
2003
Strain-Specific Manifestation of Lupus-like Systemic Autoimmunity Caused by Zap70 Mutation
2019 StandoutNobel
PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
2011 StandoutNobel
Emapalumab in Children with Primary Hemophagocytic Lymphohistiocytosis
2020
Primary and secondary hemophagocytic lymphohistiocytosis: clinical features, pathogenesis and therapy
2009
Restimulation‐induced cell death: new medical and research perspectives
2017
The Plasma Membrane: A Platform for Intra- and Intercellular Redox Signaling
2018
Pathogenesis of Macrophage Activation Syndrome and Potential for Cytokine- Directed Therapies
2014
Cytokine Storm
2020 Standout
Combination of lymphocyte number and function in evaluating host immunity
2019
Activation and Differentiation of Autoreactive B-1 Cells by Interleukin 10 Induce Autoimmune Hemolytic Anemia in Fas-deficient Antierythrocyte Immunoglobulin Transgenic Mice
2002 StandoutNobel
Familial and Acquired Hemophagocytic Lymphohistiocytosis
2011
How I treat hemophagocytic lymphohistiocytosis
2011
SLAM Family Receptors and SAP Adaptors in Immunity
2011
X-linked lymphoproliferative syndromes: brothers or distant cousins?
2010
Induction of Robust Cellular and Humoral Virus-Specific Adaptive Immune Responses in Human Immunodeficiency Virus-Infected Humanized BLT Mice
2009
COVID-19 and its implications for thrombosis and anticoagulation
2020 Standout
Whole‐Exome Sequencing Reveals Overlap Between Macrophage Activation Syndrome in Systemic Juvenile Idiopathic Arthritis and Familial Hemophagocytic Lymphohistiocytosis
2014
Regulatory roles of IL-10–producing human follicular T cells
2019 StandoutNobel
Review: Cytokine Storm Syndrome: Looking Toward the Precision Medicine Era
2017
Dendritic cells induce antigen-specific regulatory T cells that prevent graft versus host disease and persist in mice
2011 StandoutNobel
IAP inhibitors enhance co-stimulation to promote tumor immunity
2010
Hematological Problems in Pediatric Intensive Care
2013 Standout
Increased mTOR activation in idiopathic multicentric Castleman disease
2020
Dysregulation of Immune Response in Patients With Coronavirus 2019 (COVID-19) in Wuhan, China
2020 Standout
Serial time-encoded amplified imaging for real-time observation of fast dynamic phenomena
2009 Nature
Gene expression profiling of peripheral blood from patients with untreated new‐onset systemic juvenile idiopathic arthritis reveals molecular heterogeneity that may predict macrophage activation syndrome
2007
Etoposide Selectively Ablates Activated T Cells To Control the Immunoregulatory Disorder Hemophagocytic Lymphohistiocytosis
2013
Works of Jack Bleesing being referenced
Restimulation-induced apoptosis of T cells is impaired in patients with X-linked lymphoproliferative disease caused by SAP deficiency
2009
Treatment with sirolimus results in complete responses in patients with autoimmune lymphoproliferative syndrome
2009
The diagnostic significance of soluble CD163 and soluble interleukin‐2 receptor α‐chain in macrophage activation syndrome and untreated new‐onset systemic juvenile idiopathic arthritis
2007
A Composite Picture of TcRα/β+ CD4−CD8− T Cells (α/β-DNTCs) in Humans with Autoimmune Lymphoproliferative Syndrome
2002
Reduced-Intensity Conditioning Hematopoietic Cell Transplantation Is an Effective Treatment for Patients with SLAM-Associated Protein Deficiency/X-linked Lymphoproliferative Disease Type 1
2014
A rapid flow cytometric screening test for X‐linked lymphoproliferative disease due to XIAP deficiency
2009
Human B cells express a CD45 isoform that is similar to murine B220 and is downregulated with acquisition of the memory B‐cell marker CD27
2002
Use of intravenous immunoglobulin and adjunctive therapies in the treatment of primary immunodeficiencies
2009
Familial haemophagocytic lymphohistiocytosis in patients who are heterozygous for the A91V perforin variation is often associated with other genetic defects
2007
Using flow cytometry to screen patients for X-linked lymphoproliferative disease due to SAP deficiency and XIAP deficiency
2010
TcR-α/β+ CD4−CD8− T Cells in Humans with the Autoimmune Lymphoproliferative Syndrome Express a Novel CD45 Isoform That Is Analogous to Murine B220 and Represents a Marker of Altered O-Glycan Biosynthesis
2001
Patients with X-linked lymphoproliferative disease due to BIRC4 mutation have normal invariant natural killer T-cell populations
2009
Functional reprogramming of regulatory T cells in the absence of Foxp3
2019
Salvage therapy of refractory hemophagocytic lymphohistiocytosis with alemtuzumab
2012
Persistent Enteropathy in a Toddler with a Novel FOXP3 Mutation and Normal FOXP3 Protein Expression
2017
Contemporary diagnostic methods for hemophagocytic lymphohistiocytic disorders
2010
AUTOIMMUNE LYMPHOPROLIFERATIVE SYNDROME
2000
Introduction to flow cytometry
2001
The Autoimmune Lymphoproliferative Syndrome
2001
XIAP deficiency: a unique primary immunodeficiency best classified as X-linked familial hemophagocytic lymphohistiocytosis and not as X-linked lymphoproliferative disease
2010
Revised diagnostic criteria and classification for the autoimmune lymphoproliferative syndrome (ALPS): report from the 2009 NIH International Workshop
2010
Perforin and CD107a testing is superior to NK cell function testing for screening patients for genetic HLH
2017
Patients with Chronic Granulomatous Disease Have a Reduced Peripheral Blood Memory B Cell Compartment
2006
Immunophenotypic profiles in families with autoimmune lymphoproliferative syndrome
2001
Sirolimus is effective in relapsed/refractory autoimmune cytopenias: results of a prospective multi-institutional trial
2015
Reduced-intensity conditioning significantly improves survival of patients with hemophagocytic lymphohistiocytosis undergoing allogeneic hematopoietic cell transplantation
2010
Increases in circulating and lymphoid tissue interleukin-10 in autoimmune lymphoproliferative syndrome are associated with disease expression
2001
Differential role of nonhomologous end joining factors in the generation, DNA damage response, and myeloid differentiation of human induced pluripotent stem cells
2014