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Citing Papers
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Structural Roles for Human Translation Factor eIF3 in Initiation of Protein Synthesis
2005 StandoutScienceNobel
Stepwise progression of B lineage differentiation supported by interleukin 7 and other stromal cell molecules.
1990
Functional domains of the granulocyte colony-stimulating factor receptor.
1991
Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction.
1993
The mystery of nonclassical protein secretion
2003
Phosphorylation of Cell Surface Receptors: A Mechanism for Regulating Signal Transduction Pathways
1988 StandoutNobel
Prostaglandin synthase 1 gene disruption in mice reduces arachidonic acid-induced inflammation and indomethacin-induced gastric ulceration
1995 StandoutNobel
Molecular and biological characterization of a murine ligand for CD40
1992 Nature
Activation of interleukin‐ 1β by a co‐induced protease
1989
The Epstein-Barr virus transforming protein LMP1 engages signaling proteins for the tumor necrosis factor receptor family
1995
Signal transduction in the control of cell growth and development
1991
Molecular cloning of a ligand for the flt3flk-2 tyrosine kinase receptor: A proliferative factor for primitive hematopoietic cells
1993
Diffusible factors in vertebrate embryonic induction
1992
A protein-conducting channel in the endoplasmic reticulum
1991 StandoutNobel
The receptor DEC-205 expressed by dendritic cells and thymic epithelial cells is involved in antigen processing
1995 StandoutNatureNobel
Cloning of the human and murine interleukin-7 receptors: Demonstration of a soluble form and homology to a new receptor superfamily
1990
Myxoma virus expresses a secreted protein with homology to the tumor necrosis factor receptor gene family that contributes to viral virulence
1991
High susceptibility to ultraviolet-induced carcinogenesis in mice lacking XPC
1995 Nature
An Evolutionary and Functional Approach to the TNF Receptor/Ligand Family
1994 StandoutNobel
Herpesvirus Saimiri encodes a new cytokine, IL-17, which binds to a novel cytokine receptor
1995
Molecular Events Mediating T Cell Activation
1990
The Dorsoventral Regulatory Gene Cassette spätzle/Toll/cactus Controls the Potent Antifungal Response in Drosophila Adults
1996 StandoutNobel
Molecular and biological characterization of a ligand for CD27 defines a new family of cytokines with homology to tumor necrosis factor
1993
The origin of pattern and polarity in the Drosophila embryo
1992 StandoutNobel
c-Kit Ligand Mediates Increased Expression of Cytosolic Phospholipase A2, Prostaglandin Endoperoxide Synthase-1, and Hematopoietic Prostaglandin D2 Synthase and Increased IgE-dependent Prostaglandin D2 Generation in Immature Mouse Mast Cells
1995
Bcl-2 Can Rescue T Lymphocyte Development in Interleukin-7 Receptor–Deficient Mice but Not in Mutant rag-1 −/− Mice
1997
Cytokine Pathways and Joint Inflammation in Rheumatoid Arthritis
2001 Standout
Mechanisms of asymmetric cell division: Two Bs or not two Bs, that is the question
1992 StandoutNobel
The product of the tobacco mosaic virus resistance gene N: Similarity to toll and the interleukin-1 receptor
1994
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins
1994 StandoutNobel
Inflammatory Mediators, Cytokines, and Adhesion Molecules in Pulmonary Inflammation and Injury
1996
Regulation of receptor-mediated endocytosis by phorbol esters
1991
A zonal organization of odorant receptor gene expression in the olfactory epithelium
1993 StandoutNobel
Therapeutic targeting of Toll-like receptors for inflammatory and infectious diseases
2003
Cytokine signal transduction
1994
Ligation of CD40 Activates Interleukin 1β-converting Enzyme (Caspase-1) Activity in Vascular Smooth Muscle and Endothelial Cells and Promotes Elaboration of Active Interleukin 1β
1997
Molecular cloning, functional expression, and signaling characteristics of a C-C chemokine receptor
1993
Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor
1997 StandoutNatureNobel
B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40
1993 StandoutNatureNobel
HIV infection does not require endocytosis of its receptor, CD4
1988 StandoutNobel
The TNF receptor superfamily of cellular and viral proteins: Activation, costimulation, and death
1994 Standout
Atherosclerosis — An Inflammatory Disease
1999 Standout
Identification of a source of biologically active CD40 ligand
1992
Two vaccinia virus proteins structurally related to the interleukin-1 receptor and the immunoglobulin superfamily
1991
Identification of Clonogenic Common Lymphoid Progenitors in Mouse Bone Marrow
1997 Standout
Molecular cloning of a ligand for the inducible T cell gene 4‐1BB: a member of an emerging family of cytokines with homology to tumor necrosis factor
1993
Differentiation inhibiting activity () and mouse development
1992
C/EBP is an immediate-early gene required for the consolidation of long-term facilitation in Aplysia
1994 StandoutNobel
Lack of IL-4-induced Th2 response and IgE class switching in mice with disrupted State6 gene
1996 StandoutNatureNobel
Cytokine and Cytokine Receptor Pleiotropy and Redundancy
2002
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing
1994 Nature
A metalloproteinase disintegrin that releases tumour-necrosis factor-α from cells
1997 StandoutNature
TGFα deficiency results in hair follicle and eye abnormalities in targeted and waved-1 mice
1993 StandoutNobel
The Structure and Insertion of Integral Proteins in Membranes
1990
A homologue of the TNF receptor and its ligand enhance T-cell growth and dendritic-cell function
1997 StandoutNature
The Molecular Basis of X‐Linked Severe Combined Immunodeficiency: The Role of the Interleukin‐2 Receptor γ Chain as a Common γ Chain, γc
1994
Inferences, questions and possibilities in Toll-like receptor signalling
2004 StandoutNatureNobel
Viral inhibition of inflammation: Cowpox virus encodes an inhibitor of the interleukin-1β converting enzyme
1992 Standout
Fluorescent indicators for Ca2+based on green fluorescent proteins and calmodulin
1997 StandoutNatureNobel
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Inhibition of the Caenorhabditis elegans cell-death protease CED-3 by a CED-3 cleavage site in baculovirus p35 protein
1995 StandoutNatureNobel
Mouse hematopoietic stem cells and the interaction ofc‐kirreceptor and steel factor
1991
Generation of Lymphohematopoietic Cells from Embryonic Stem Cells in Culture
1994 StandoutScienceNobel
Interleukin-2 Receptor γ Chain: a Functional Component of the Interleukin-7 Receptor
1993 Science
Early lymphocyte expansion is severely impaired in interleukin 7 receptor-deficient mice.
1994
Evidence that hematopoietic stem cells express mouse c-kit but do not depend on steel factor for their generation.
1992
In Vitro Development of Primitive and Definitive Erythrocytes from Different Precursors
1996 StandoutScienceNobel
Interleukin 7 is a T-cell growth factor.
1989
Recombinant interleukin 7, pre-B cell growth factor, has costimulatory activity on purified mature T cells.
1989
Interleukin 1 and tumor necrosis factor stimulate two novel protein kinases that phosphorylate the heat shock protein hsp27 and beta-casein.
1993
Macrophage lineage switching of murine early pre-B lymphoid cells expressing transduced fms genes.
1990
Serotonin-Mediated Endocytosis of apCAM: an Early Step of Learning-Related Synaptic Growth in Aplysia
1992 StandoutScienceNobel
Expression of murine interleukin 7 in a murine glioma cell line results in reduced tumorigenicity in vivo.
1992 StandoutNobel
Differentiation of growth signal requirement of B lymphocyte precursor is directed by expression of immunoglobulin.
1991 StandoutNobel
PLANT DISEASE RESISTANCE GENES
1997 Standout
Lymphopenia in interleukin (IL)-7 gene-deleted mice identifies IL-7 as a nonredundant cytokine.
1995
Expression and function of the interleukin 7 receptor in murine lymphocytes.
1993
Rapid phosphorylation and modulation of the T4 antigen on cloned helper T cells induced by phorbol myristate acetate or antigen.
1986
Quality Control by DNA Repair
1999 StandoutScienceNobel
A conserved signal transduction pathway regulating the activity of the rel-like proteins dorsal and NF-kappa B.
1993
Substrate specificity of the protease that processes human interleukin-1 beta.
1990
Long-term proliferating early pre B cell lines and clones with the potential to develop to surface Ig-positive, mitogen reactive B cells in vitro and in vivo.
1991
Interleukin 7 production and function in stromal cell-dependent B cell development.
1989
Human interleukin 7: molecular cloning and growth factor activity on human and murine B-lineage cells.
1989
Resolution and characterization of pro-B and pre-pro-B cell stages in normal mouse bone marrow.
1991
Amino acids conserved in interleukin-1 receptors (IL-1Rs) and the Drosophila toll protein are essential for IL-1R signal transduction.
1992
Requirement of Mip-1α for an Inflammatory Response to Viral Infection
1995 StandoutScienceNobel
Enrichment and characterization of murine hematopoietic stem cells that express c-kit molecule
1991
An Interleukin-4-Induced Transcription Factor: IL-4 Stat
1994 Science
LAG-3, a novel lymphocyte activation gene closely related to CD4.
1990
Establishment of an interleukin-5-dependent subclone from an interleukin-3-dependent murine hemopoietic progenitor cell line, LyD9, and its malignant transformation by autocrine secretion of interleukin-5.
1990 StandoutNobel
Role of macrophage colony-stimulating factor in atherosclerosis: studies of osteopetrotic mice.
1997
A stimulatory effect of recombinant murine interleukin-7 (IL-7) on B- cell colony formation and an inhibitory effect of IL-1 alpha
1989
Utilization of the beta and gamma chains of the IL-2 receptor by the novel cytokine IL-15.
1994
Purification and Characterization of Human Recombinant Precursor Interleukin 1 β
1989
Interleukin 6: A Multifunctional Cytokine Regulating Immune Reactions and the Acute Phase Protein Response
1990
Expression and function of c-Kit in fetal hemopoietic progenitor cells: transition from the early c-Kit-independent to the late c-Kit-dependent wave of hemopoiesis in the murine embryo
1993
Human interleukin 4 receptor confers biological responsiveness and defines a novel receptor superfamily.
1990
Signal Sequence Trap: a Cloning Strategy for Secreted Proteins and Type I Membrane Proteins
1993 StandoutScienceNobel
Hematopoietic cytokines
2008
The future of immune checkpoint therapy
2015 StandoutScienceNobel
Expression and function of c-kit in hemopoietic progenitor cells.
1991
Identification of a monocyte specific pre-interleukin 1 beta convertase activity.
1989
Molecular Cloning of the Interleukin-1β Converting Enzyme
1992 Science
Cytokine Signaling Through Nonreceptor Protein Tyrosine Kinases
1995 StandoutScience
Transposon tagging of tobacco mosaic virus resistance gene N: its possible role in the TMV-N-mediated signal transduction pathway.
1995
Cytokine Receptors and Signal Transduction
1992
Antagonism of Catecholamine Receptor Signaling by Expression of Cytoplasmic Domains of the Receptors
1993 StandoutScienceNobel
Molecular cloning and expression of the murine interleukin-5 receptor.
1990
Hematopoietic development of embryonic stem cells in vitro: cytokine and receptor gene expression.
1991
Dominant and recessive mutations define functional domains of Toll, a transmembrane protein required for dorsal-ventral polarity in the Drosophila embryo.
1991
Expression cloning of a receptor for human granulocyte-macrophage colony-stimulating factor.
1989
Molecular cloning of pancreatic group I phospholipase A2 receptor.
1994
Critical cytoplasmic region of the interleukin 6 signal transducer gp130 is conserved in the cytokine receptor family.
1991
Expression cloning of a human granulocyte colony-stimulating factor receptor: a structural mosaic of hematopoietin receptor, immunoglobulin, and fibronectin domains.
1990
Interleukin-1 represents a new modality for the activation of extracellular signal-regulated kinases/microtubule-associated protein-2 kinases.
1991
Cloning of a T Cell Growth Factor that Interacts with the β Chain of the Interleukin-2 Receptor
1994 StandoutScience
The scanning model for translation: an update.
1989 Standout
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Unconventional Secretion, Unconventional Solutions
2013 StandoutScienceNobel
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Interleukin-1 and interleukin-1 antagonism
1991 Standout
Molecular characterization of murine and human OX40/OX40 ligand systems: identification of a human OX40 ligand as the HTLV-1-regulated protein gp34.
1994 StandoutNobel
Sharing of the Interleukin-2 (IL-2) Receptor γ Chain Between Receptors for IL-2 and IL-4
1993 Science
Soluble receptors for cytokines and growth factors: generation and biological function
1994
Signaling in Plant-Microbe Interactions
1997 Science
A Receptor for Tumor Necrosis Factor Defines an Unusual Family of Cellular and Viral Proteins
1990 Science
Identification of cysteine-rich domains of the type 1 tumor necrosis factor receptor involved in ligand binding.
1992
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
Works of J Wignall being referenced
Stimulation of B-cell progenitors by cloned murine interleukin-7
1988 Nature
Human macrophage-colony stimulating factor: Alternative RNA and protein processing from a single gene
1988
Molecular cloning of mast cell growth factor, a hematopoietin that is active in both membrane bound and soluble forms
1990
T2 open reading frame from the shope fibroma virus encodes a soluble form of the TNF receptor
1991
The murine interleukin-4 receptor: Molecular cloning and characterization of secreted and membrane bound forms
1989
cDNA Expression Cloning of the IL-1 Receptor, a Member of the Immunoglobulin Superfamily
1988 Science
Generation of biologically active interleukin-1 beta by proteolytic cleavage of the inactive precursor.
1988
Phosphorylation of the human interleukin-2 receptor and a synthetic peptide identical to its C-terminal, cytoplasmic domain.
1986
Cloning the interleukin 1 receptor from human T cells.
1989
A novel IL-1 receptor, cloned from B cells by mammalian expression, is expressed in many cell types.
1991
Retention of ligand binding activity by the extracellular domain of the IL-1 receptor.
1989