Citation Impact
Citing Papers
Insulin Resistance and a Diabetes Mellitus-Like Syndrome in Mice Lacking the Protein Kinase Akt2 (PKBβ)
2001 StandoutScience
Inflammation and metabolic disorders
2006 StandoutNature
15-Deoxy-Δ12,14-Prostaglandin J2 is a ligand for the adipocyte determination factor PPARγ
1995 Standout
Insulin receptor phosphorylation, insulin receptor substrate-1 phosphorylation, and phosphatidylinositol 3-kinase activity are decreased in intact skeletal muscle strips from obese subjects.
1995
Lipolysis and lipid mobilization in human adipose tissue
2009
Protection from obesity-induced insulin resistance in mice lacking TNF-α function
1997 StandoutNature
Characterization of selective resistance to insulin signaling in the vasculature of obese Zucker (fa/fa) rats
1999
Effects of the tumour promoter okadaic acid on intracellular protein phosphorylation and metabolism
1989 StandoutNature
PPAR-γ agonists inhibit production of monocyte inflammatory cytokines
1998 StandoutNature
Severe impairment in liver insulin signaling fails to alter hepatic insulin action in conscious mice
2005
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Brown adipose tissue thermogenic adaptation requires Nrf1-mediated proteasomal activity
2018 StandoutNobel
Mechanisms linking obesity to insulin resistance and type 2 diabetes
2006 StandoutNature
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
Insulin resistance differentially affects the PI 3-kinase– and MAP kinase–mediated signaling in human muscle
2000
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Transcriptional co-activator PGC-1α drives the formation of slow-twitch muscle fibres
2002 StandoutNature
Biochemistry and molecular cell biology of diabetic complications
2001 StandoutNature
Low birthweight is associated with specific changes in muscle insulin-signalling protein expression
2005
Regulation of insulin receptor function
2007
Obesity and the Regulation of Energy Balance
2001 Standout
Inflammation, metaflammation and immunometabolic disorders
2017 StandoutNature
Insulin Signaling and Glucose Transport in Insulin Resistant Skeletal Muscle
1998
Effect of In Utero and Early-Life Conditions on Adult Health and Disease
2008 Standout
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Coated pits, coated vesicles, and receptor-mediated endocytosis
1979 StandoutNatureNobel
Mechanism of activation of adenylate cyclase byVibrio cholerae enterotoxin
1975
Insulin-stimulated Hexose Transport and Glucose Oxidation in rat Adipocytes Is Inhibited by Sphingosine at a Step after Insulin Binding
1989
Human insulin receptor and its relationship to the tyrosine kinase family of oncogenes
1985 StandoutNature
Insulin-stimulated translocation of glucose transport systems in the isolated rat adipose cell. Time course, reversal, insulin concentration dependency, and relationship to glucose transport activity.
1981
Differences in the sites of phosphorylation of the insulin receptor in vivo and in vitro.
1985
Evidence that translocation of the glucose transport activity is the major mechanism of insulin action on glucose transport in fat cells.
1982
Covalent linking of photoreactive insulin to adipocytes produces a prolonged signal
1980 Nature
Tumor necrosis factor alpha inhibits signaling from the insulin receptor.
1994
Energy-dependent and protein synthesis-independent recycling of the insulin-sensitive glucose transport mechanism in fat cells.
1981
Mechanisms of Insulin Action and Insulin Resistance
2018 Standout
beta-Adrenergic regulation of insulin and epidermal growth factor receptors in rat adipocytes.
1983
Regulation of transmembrane signaling by receptor phosphorylation
1987 StandoutNobel
Proposed mechanism of insulin-resistant glucose transport in the isolated guinea pig adipocyte. Small intracellular pool of glucose transporters.
1983 StandoutNobel
Heterogeneity of radioligand binding to alpha-adrenergic receptors. Analysis of guanine nucleotide regulation of agonist binding in relation to receptor subtypes.
1980 StandoutNobel
The role of hormone receptors and GTP-regulatory proteins in membrane transduction
1980 StandoutNatureNobel
The influence of bound GDP on the kinetics of guanine nucleotide binding to G proteins.
1986 StandoutNobel
Reversible activation of hepatic adenylate cyclase by guanyl-5'-yl-(alpha,beta-methylene)diphosphonate and guanyl-5'-yl imidodiphosphate.
1977 StandoutNobel
Insulin effect on protein phosphorylation of plasma membranes and mitochondria in a subcellular system from rat adipocytes. I. Identification of insulin-sensitive phosphoproteins.
1979
Partial purification of the D-glucose transport system in rat adipocyte plasma membranes.
1977
The Insulin-Sensitive Glucose Transporter
1992
Mechanism of insulin action on glucose transport in the isolated rat adipose cell. Enhancement of the number of functional transport systems.
1978
Selection of an RNA molecule that mimics a major autoantigenic epitope of human insulin receptor.
1995 StandoutNobel
Reversal of Obesity- and Diet-Induced Insulin Resistance with Salicylates or Targeted Disruption of Ikkβ
2001 StandoutScience
Fractionation of endocytic vesicles and glucose-transporter-containing vesicles in rat adipocytes
1988
Ultrastructural localization of insulin receptors on adipocytes.
1975
The asialoglycoprotein receptor internalizes and recycles independently of the transferrin and insulin receptors
1983 StandoutNobel
Insulin action and resistance in obesity and noninsulin-dependent type II diabetes mellitus
1982
Analogs that compete for antigen binding to an arsonate-reactive T-cell clone inhibit the functional response to arsonate
1984
Membrane-permeant Esters of Phosphatidylinositol 3,4,5-Trisphosphate
1998 StandoutNobel
Analysis of GLUT4 Distribution in Whole Skeletal Muscle Fibers: Identification of Distinct Storage Compartments That Are Recruited by Insulin and Muscle Contractions
1998
Restoration of insulin-sensitive glucose transporter (GLUT4) gene expression in muscle cells by the transcriptional coactivator PGC-1
2001
Adipocyte beta-adrenergic receptors. Identification and subcellular localization by (-)-[3H]dihydroalprenolol binding.
1976 StandoutNobel
Secretin Promotes Osmotic Water Transport in Rat Cholangiocytes by Increasing Aquaporin-1 Water Channels in Plasma Membrane
1997 StandoutNobel
Actions of insulin in fat cells. Effects of low temperature, uncouplers of oxidative phosphorylation, and respiratory inhibitors.
1977
Binding and receptor-mediated degradation of insulin in adipocytes
1978
Interaction of cross-linking agents with the insulin effector system of isolated fat cells. Covalent linkage of 125I-insulin to a plasma membrane receptor protein of 140,000 daltons.
1979
Increased Energy Expenditure, Decreased Adiposity, and Tissue-Specific Insulin Sensitivity in Protein-Tyrosine Phosphatase 1B-Deficient Mice
2000
The glucose transporter family: structure, function and tissue-specific expression
1993
The Role of Calcium in Insulin Action
1975
Potential mechanism of insulin action on glucose transport in the isolated rat diaphragm. Apparent translocation of intracellular transport units to the plasma membrane.
1981
Two-dimensional crystals of cholera toxin B-subunit-receptor complexes: projected structure at 17-A resolution.
1986 StandoutNobel
The effect of insulin on the washout of [45Ca]calcium from adipocytes and soleus muscle of the rat
1977
Mechanism of Insulin-resistant Glucose Transport Activity in the Enlarged Adipose Cell of the Aged, Obese Rat
1982
Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin Resistance
1993 StandoutScience
Irreversible stimulation of adenylate cyclase activity of fat cell membranes by phosphoramidate and phosphonate analogs of GTP
1975
The mobile receptor hypothesis and “cooperativity” of hormone binding. Application to insulin
1976
Effects of Endurance Training on Glucose Tolerance and Plasma Lipid Levels in Older Men and Women
1984
What is the molecular basis for the action of insulin?
1979
cAMP-dependent protein kinase and lipolysis in rat adipocytes. I. Cell preparation, manipulation, and predictability in behavior.
1985
Dose-response characteristics for effects of insulin on production and utilization of glucose in man
1981
A ternary complex model explains the agonist-specific binding properties of the adenylate cyclase-coupled beta-adrenergic receptor.
1980 StandoutNobel
Evidence that insulin causes translocation of glucose transport activity to the plasma membrane from an intracellular storage site.
1980
β-adrenoceptor studies. 6. Further investigations on the hybrid nature of the rat adipocyte β-adrenoceptor
1980
Okadaic acid mimics the action of insulin in stimulating protein kinase activity in isolated adipocytes. The role of protein phosphatase 2a in attenuation of the signal.
1990 StandoutNobel
Activation of adenylate cyclase in hepatic membranes involves interactions of the catalytic unit with multimeric complexes of regulatory proteins.
1979 StandoutNobel
Exercise, Glucose Transport, and Insulin Sensitivity
1998
Insulin and glucose 6-phosphate stimulation of Ca2+ uptake by skinned muscle fibers.
1980 StandoutNobel
Molecular Characterization of the Human β 3 -Adrenergic Receptor
1989 StandoutScience
Direct effect of insulin on the labeling of isolated plasma membranes by [γ32P] ATP
1978
Relationship between the beta-adrenergic receptor and adenylate cyclase.
1977 StandoutNobel
Resolution of beta-adrenergic receptor binding and adenylate cyclase activity by gel exclusion chromatography.
1977 StandoutNobel
A subset of T cell receptors associated with L3T4 molecules mediates C6VL leukemia cell binding of its cognate retrovirus
1987 StandoutNobel
Increased phosphorylation of ribosomal protein S6 following microinjection of insulin receptor-kinase into Xenopus oocytes
1986 StandoutNatureNobel
Essential role of phosphatidylinositol 3-kinase in insulin-induced glucose transport and antilipolysis in rat adipocytes. Studies with a selective inhibitor wortmannin.
1994
Complete sequence of the bithorax complex of Drosophila.
1995 StandoutNobel
The properties and extracellular location of 5′-nucleotidase of the rat fat-cell plasma membrane
1975
Isoproterenol stimulates shift of G proteins from plasma membrane to pinocytotic vesicles in rat adipocytes: a possible means of signal dissemination.
1990 StandoutNobel
Potential mechanism of insulin action on glucose transport in the isolated rat adipose cell. Apparent translocation of intracellular transport systems to the plasma membrane.
1980
Fluid‐phase endocytosis by isolated rat adipocytes
1984
Rapid enhancement of protein phosphorylation in A-431 cell membrane preparations by epidermal growth factor.
1979 StandoutNobel
Elective induction versus spontaneous labor after sonographic diagnosis of fetal macrosomia.
1993 Standout
Mechanism of action of cholera toxin and the mobile receptor theory of hormone receptor-adenylate cyclase interactions.
1975
Structural organization of the human insulin receptor ectodomain
1992
Human Aging: Usual and Successful
1987 StandoutScience
IRS-1-Mediated Inhibition of Insulin Receptor Tyrosine Kinase Activity in TNF-α- and Obesity-Induced Insulin Resistance
1996 StandoutScience
Lipid raft microdomain compartmentalization of TC10 is required for insulin signaling and GLUT4 translocation
2001
Insulin binding to the human lymphocyte receptor. Evaluation of the negative cooperativity model.
1977
Co-translational membrane integration of calcium pump protein without signal sequence cleavage
1981 StandoutNatureNobel
Works of J. Vinten being referenced
Expression of insulin regulatable glucose transporters in skeletal muscle from Type 2 (non-insulin-dependent) diabetic patients
1990
Decreased skeletal muscle phosphotyrosine phosphatase (PTPase) activity towards insulin receptors in insulin-resistant Zucker rats measured by delayed Europium fluorescence
1996
Altered basal and insulin-stimulated phosphotyrosine phosphatase (PTPase) activity in skeletal muscle from NIDDM patients compared with control subjects
1996
Decreased tyrosine kinase activity in partially purified insulin receptors from muscle of young, non-obese first degree relatives of patients with Type 2 (non-insulin-dependent) diabetes mellitus
1993
Quantitation of Na+/K+-ATpase and glucose transporter isoforms in rat adipocyte plasma membrane by immunogold labeling
1993
Kinetics of glucose transport in rat skeletal muscle membrane vesicles: effects of insulin and contractions
1992
Effect of training on epinephrine-stimulated lipolysis determined by microdialysis in human adipose tissue
1995
Kinetics of glucose transport in rat muscle: effects of insulin and contractions
1987
Time course of insulin-receptor binding and insulin-induced lipogenesis in isolated rat fat cells.
1975
The effect of physical training on insulin secretion of rat pancreatic islets
1981
Exchange of 3-O-methylglucose in isolated fat cells. Concentration dependence and effect of insulin.
1976
Lipogenesis and insulin sensitivity of single fat cells*
1974
A model for the quaternary structure of human placental insulin receptor deduced from electron microscopy.
1991
A procedure for measurement of distribution spaces in isolated fat cells
1972
Effect of physical training on glucose transporters in fat cell fractions
1985
Effect of endurance training on glucose transport capacity and glucose transporter expression in rat skeletal muscle
1990