Citation Impact
Citing Papers
Cell Death: The Significance of Apoptosis
1980 Standout
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
Nonalcoholic steatohepatitis
1996
Apoptosis and the regulation of cell numbers in normal and neoplastic tissues: an overview
1992
Obesity and nonalcoholic fatty liver disease: From pathophysiology to therapeutics
2018
Nonalcoholic steatohepatitis and cryptogenic cirrhosis within kindreds
2000
JM2, encoding a fork head–related protein, is mutated in X-linked autoimmunity–allergic disregulation syndrome
2000
Cell Death Mechanisms and the Immune System
1991
Hepatic cytochrome P450 2E1 is increased in patients with nonalcoholic steatohepatitis
1998
Growth factors as survival factors: Regulation of apoptosis
1994
Nonalcoholic steatohepatitis: An expanded clinical entity
1994
Identification of mismatch repair genes and their role in the development of cancer
1995
Nonalcoholic steatohepatitis: Tightening the morphological screws on a hepatic rambler
1995
Steatosis: Co-factor in Other Liver Diseases *
2005
Apoptosis: Mechanisms and Roles in Pathology
1991
IL3-Dependent Cells Die by Apoptosis on Removal of their Growth Factor
1991
Independent predictors of liver fibrosis in patients with nonalcoholic steatohepatitis
1999
Clinical and molecular features of the immunodysregulation, polyendocrinopathy, enteropathy, X linked (IPEX) syndrome
2002
Plasma transforming growth factor‐β1 level and efficacy of α‐tocopherol in patients with non‐alcoholic steatohepatitis: a pilot study
2001
The C. elegans Cell Corpse Engulfment Gene ced-7 Encodes a Protein Similar to ABC Transporters
1998 StandoutNobel
A pilot study of pioglitazone treatment for nonalcoholic steatohepatitis† ‡
2004
Nonalcoholic Fatty Liver Disease
2002 Standout
The generation of diversity and pattern in animal development
1992 StandoutNobel
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
1998 StandoutNatureNobel
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Frequency of nonalcoholic steatohepatitis as a cause of advanced liver disease
2001
Genetic pathways in colorectal and other cancers
1999
Hemochromatosis and Iron-Overload Screening in a Racially Diverse Population
2005
Mitochondrial abnormalities in non-alcoholic steatohepatitis
1999
Natural history of chronic hepatitis C
2002
Hepatitis C virus does not cause nonalcoholic steatohepatitis
1992
FOXP3 acts as a rheostat of the immune response
2005
Mechanisms and Functions of Cell Death
1991 Standout
Apoptosis (the 1992 Frank Rose Memorial Lecture)
1993
The Hallmarks of Cancer
2000 Standout
Lessons from Hereditary Colorectal Cancer
1996 Standout
An Alternatively Spliced C. elegans ced-4 RNA Encodes a Novel Cell Death Inhibitor
1996 StandoutNobel
Ursodeoxycholic Acid or Clofibrate in the Treatment of Non–Alcohol–Induced Steatohepatitis: A Pilot Study
1996
Therapeutic effects of restricted diet and exercise in obese patients with fatty liver
1997
Liver fibrosis in overweight patients
2000
Prospects for a vaccine against the hepatitis C virus
2005 StandoutNatureNobel
Structures of Human Exonuclease 1 DNA Complexes Suggest a Unified Mechanism for Nuclease Family
2011 StandoutNobel
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
A role of PIEZO1 in iron metabolism in mice and humans
2021 StandoutNobel
Non-alcoholic fatty liver disease
2021 Standout
Development of nonalcoholic fatty liver disease after orthotopic liver transplantation for cryptogenic cirrhosis
2001
Reduced expression of Dicer associated with poor prognosis in lung cancer patients
2005
The C. elegans Protein EGL-1 Is Required for Programmed Cell Death and Interacts with the Bcl-2–like Protein CED-9
1998 StandoutNobel
Progression of NAFLD to diabetes mellitus, cardiovascular disease or cirrhosis
2013
Prospective Evaluation of Unexplained Chronic Liver Transaminase Abnormalities in Asymptomatic and Symptomatic Patients
1999
Use of 5-fluorouracil and survival in patients with microsatellite-unstable colorectal cancer
2004
Pioglitazone versus vitamin E versus placebo for the treatment of non-diabetic patients with non-alcoholic steatohepatitis: PIVENS trial design
2008
Fatty liveran additional and treatable feature of the insulin resistance syndrome
1999
Nonalcoholic Steatohepatitis in Children
2000
A Review and Mathematical Analysis of Circadian Rhythms in Cell Proliferation in Mouse, Rat, and Human Epidermis
1991
Increased hepatic iron concentration in nonalcoholic steatohepatitis is associated with increased fibrosis
1998
Hepatic iron and nonalcoholic fatty liver disease
1999
Hereditary Colorectal Cancer
2003 Standout
Apoptosis in Myocytes in End-Stage Heart Failure
1996
Alterations in Liver ATP Homeostasis in Human Nonalcoholic Steatohepatitis
1999
Nonalcoholic Steatohepatitis: A Proposal for Grading and Staging The Histological Lesions
1999 Standout
Association of Histologic Disease Activity With Progression of Nonalcoholic Fatty Liver Disease
2019
Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer
1995
Vitamin E and vitamin C treatment improves fibrosis in patients with nonalcoholic steatohepatitis
2003
Idiopathic steatohepatitis in childhood: A multicenter retrospective study
1995
Nonalcoholic fatty liver disease: A spectrum of clinical and pathological severity☆, ☆☆
1999 Standout
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Cryptogenic Cirrhosis: Clinical Characterization and Risk Factors for Underlying Disease
1999
REVIEW: Nonalcoholic steatohepatitis
1997
CYP2E1 and CYP4A as microsomal catalysts of lipid peroxides in murine nonalcoholic steatohepatitis
2000
MicroRNA expression profiles classify human cancers
2005 StandoutNatureNobel
Nonalcoholic steatohepatitis: Association of insulin resistance and mitochondrial abnormalities
2001 Standout
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
Association of nonalcoholic fatty liver disease with insulin resistance
1999
Betaine, a promising new agent for patients with nonalcoholic steatohepatitis: results of a pilot study
2001
Mismatch Repair Deficiency in Phenotypically Normal Human Cells
1995 StandoutScienceNobel
Distinct patterns of KRAS mutations in colorectal carcinomas according to germline mismatch repair defects and hMLH1 methylation status
2004
Programmed Cell Death in Animal Development
1997 Standout
Past, present and future perspectives in nonalcoholic fatty liver disease
2019
Pioglitazone, Vitamin E, or Placebo for Nonalcoholic Steatohepatitis
2010 Standout
Death and the cell
1986
The TRA-1A Sex Determination Protein of C. elegans Regulates Sexually Dimorphic Cell Deaths by Repressing the egl-1 Cell Death Activator Gene
1999 StandoutNobel
Insulin resistance–associated hepatic iron overload
1999
Similarities and differences in outcomes of cirrhosis due to nonalcoholic steatohepatitis and hepatitis C†
2006
Neurodegeneration in Excitotoxicity, Global Cerebral Ischemia, and Target Deprivation: A Perspective on the Contributions of Apoptosis and Necrosis
1998
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
1994 StandoutNobel
Evidence of NAFLD progression from steatosis to fibrosing-steatohepatitis using paired biopsies: Implications for prognosis and clinical management
2014
The histological course of nonalcoholic fatty liver disease: a longitudinal study of 103 patients with sequential liver biopsies
2004
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
1998 StandoutNatureNobel
The Natural History of Nonalcoholic Fatty Liver Disease: A Population-Based Cohort Study
2005 Standout
Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.
1992
Role of DNA Mismatch Repair Defects in the Pathogenesis of Human Cancer
2003
Dual modulation of cell survival and cell death by β 2 -adrenergic signaling in adult mouse cardiac myocytes
2001 StandoutNobel
Immunohistochemistry Versus Microsatellite Instability Testing in Phenotyping Colorectal Tumors
2002
An alkylation-tolerant, mutator human cell line is deficient in strand-specific mismatch repair.
1993 StandoutNobel
Programmed cell death involved in the schizolysigenous formation of the secretory cavity in Citrus sinensis L. (Osbeck)
2010 Standout
The natural history of nonalcoholic fatty liver: A follow-up study
1995
BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.
1991
Mutations Affecting Programmed Cell Deaths in the Nematode Caenorhabditis elegans s
1983 StandoutScienceNobel
Isolation of an hMSH2-p160 Heterodimer That Restores DNA Mismatch Repair to Tumor Cells
1995 StandoutScienceNobel
Nonalcoholic Fatty Liver Disease
2001 Standout
Programmed cell death
1974
Pedigree analysis of plasmid segregation in yeast
1983 StandoutNobel
Endogenous endonuclease-induced DNA fragmentation: an early event in cell-mediated cytolysis.
1983
Morphology of programmed cell death in the ventral nerve cord ofCaenorhabditis eleganslarvae
1982
Nonalcoholic steatohepatitis: an expanded clinical entity Bacon BR, Farakvash MJ, Janney CG, Neuschwander-Tetri BA. Gastroenterology 1994; 107: 1103?1109
1995
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Receptor-stimulated death pathway is opened by antigen in mature T cells.
1991
Histopathological Identification of Colon Cancer with Microsatellite Instability
2001
Cyclin B2-null mice develop normally and are fertile whereas cyclin B1-null mice die in utero
1998 StandoutNobel
Apoptosis: a different type of cell death
1992
DNA Mismatch Repair: Functions and Mechanisms
2005 StandoutNobel
Programmed Cell Death Induced by Ceramide
1993 StandoutScience
Apoptosis and Programmed Cell Death in Immunity
1992
Chromatin cleavage in apoptosis: Association with condensed chromatin morphology and dependence on macromolecular synthesis
1984
Obesity increases sensitivity to endotoxin liver injury: Implications for the pathogenesis of steatohepatitis
1997
The Caenorhabditis elegans mucolipin-like gene cup-5 is essential for viability and regulates lysosomes in multiple cell types
2002 StandoutNobel
Neural Science
2000 StandoutNobel
Control of skin cancer by the circadian rhythm
2011 StandoutNobel
Asia–Pacific Working Party on Non‐alcoholic Fatty Liver Disease guidelines 2017—Part 1: Definition, risk factors and assessment
2017
Binding of Mismatched Microsatellite DNA Sequences by the Human MSH2 Protein
1994 Science
Monoclonal Antibody-Mediated Tumor Regression by Induction of Apoptosis
1989 StandoutScience
Emerging Challenges in Regulatory T Cell Function and Biology
2007 StandoutScienceNobel
Microsatellite instability in colorectal cancer: different mutator phenotypes and the principal involvement of hMLH1.
1998
Cell death in ovarian chambers ofDrosophila melanogaster
1976
Seppuku and Autoimmunity
1992 StandoutScienceNobel
Toward an understanding of the molecular mechanisms of physiological cell death.
1993
Mitochondria and Apoptosis
1998 StandoutScience
Tumor-infiltrating lymphocytes are a marker for microsatellite instability in colorectal carcinoma
2001
The segregation of DNA in epithelial stem cells
1978
Deregulated transcription factor E2F-1 expression leads to S-phase entry and p53-mediated apoptosis.
1994 StandoutNobel
Biallelic inactivation of hMLH 1 by epigenetic gene silencing, a novel mechanism causing human MSI cancers
1998 StandoutNobel
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
hMutSα- and hMutLα-dependent phosphorylation of p53 in response to DNA methylator damage
1999 StandoutNobel
Translocation of C. elegans CED-4 to Nuclear Membranes During Programmed Cell Death
2000 StandoutScienceNobel
Apoptosis in AIDS
1993 StandoutScienceNobel
Unraveling Function in the TNF Ligand and Receptor Families
1994 StandoutScienceNobel
Works of J. Searle being referenced
Apoptosis. Its nature and implications for dermatopathology.
1979
Morphology of sporadic colorectal cancer with DNA replication errors
1998
Distribution and morphology of UV-induced epidermal cell death
1977
Neonatal Diabetes Mellitus Associated with Severe Diarrhea, Hyperimmunoglobulin E Syndrome, and Absence of Islets of Langerhans
1995
The Natural History of Nonalcoholic Steatohepatitis: A Follow–Up Study of Forty–Two Patients for Up to 21 Years
1990
Colorectal carcinomas show frequent allelic loss on the long arm of chromosome 17 with evidence for a specific target region
1995
Familial iron overload with possible autosomal dominant inheritance
1990
Steatohepatitis associated with limb lipodystrophy
1989
Genomic instability occurs in colorectal carcinomas but not in adenomas
1993
Differential Radiation Response Amongst Proliferating Epithelial Cells
1978
THE NATURE OF PIECEMEAL NECROSIS IN CHRONIC ACTIVE HEPATITIS
1979
DEATH OF CELLS BY APOPTOSIS FOLLOWING ATTACHMENT OF SPECIFICALLY ALLERGIZED LYMPHOCYTES IN VITRO
1977
CIRCADIAN RHYTHMS OF PRESUMPTIVE STEM CELLS IN THREE DIFFERENT EPITHELIA OF THE MOUSE
1977
AN ELECTRON MICROSCOPIC STUDY OF THE MODE OF DONOR CELL DEATH IN UNMODIFIED REJECTION OF PIG LIVER ALLOGRAFTS
1977
An electron‐microscope study of the mode of cell death induced by cancer‐chemotherapeutic agents in populations of proliferating normal and neoplastic cells
1975
Apoptosis
1979
Deletion of cells by apoptosis during castration-induced involution of the rat prostate
1973
A suggested explanation for the paradoxically slow growth rate of basal‐cell carcinomas that contain numerous mitotic figures
1972
Successive waves of apoptosis in the rat prostate after repeated withdrawal of testosterone stimulation
1984
Frequent loss of heterozygosity on chromosome 14 occurs in advanced colorectal carcinomas.
1993
Characterisation of a subtype of colorectal cancer combining features of the suppressor and mild mutator pathways.
1999
The spontaneous occurrence of apoptosis in squamous carcinomas of the uterine cervix
1973
An electron-microscope study of cell deletion in the anuran tadpole tail during spontaneous metamorphosis with special reference to apoptosis of striated muscle fibres
1974
The digestion of cellular fragments within phagolysosomes in carcinoma cells
1972