Standout Papers
Citation Impact
Citing Papers
Halogen bonds in biological molecules
2004 Standout
Elevated levels of protein-bound p-hydroxyphenylacetaldehyde, an amino-acid-derived aldehyde generated by myeloperoxidase, are present in human fatty streaks, intermediate lesions and advanced atherosclerotic lesions
2000
The X-ray crystal structure of the membrane protein prostaglandin H2 synthase-1
1994 StandoutNature
Free radicals, antioxidants, and human disease: curiosity, cause, or consequence?
1994 Standout
Molecular Chlorine Generated by the Myeloperoxidase-Hydrogen Peroxide-Chloride System of Phagocytes Converts Low Density Lipoprotein Cholesterol into a Family of Chlorinated Sterols
1996
Peroxidase and Phosphatase Activity of Active-site Mutants of Vanadium Chloroperoxidase from the Fungus Curvularia inaequalis
2000
Myeloperoxidase-generated reactive nitrogen species convert LDL into an atherogenic form in vitro
1999
Kinetic and Spectroscopic Characterization of a Hydroperoxy Compound in the Reaction of Native Myoglobin with Hydrogen Peroxide
2003
Biomarkers of myeloperoxidase-derived hypochlorous acid
2000
Myeloperoxidase produces nitrating oxidants in vivo
2002
Macrophage Myeloperoxidase Regulation by Granulocyte Macrophage Colony-Stimulating Factor in Human Atherosclerosis and Implications in Acute Coronary Syndromes
2001
Estrogen receptor α is a major mediator of 17β-estradiol’s atheroprotective effects on lesion size in Apoe–/– mice
2001 StandoutNobel
X-ray crystal structure of canine myeloperoxidase at 3 Å resolution
1992
Oxidative stress: new approaches to diagnosis and prognosis in atherosclerosis
2003
p-Hydroxyphenylacetaldehyde, the Major Product of l-Tyrosine Oxidation by the Myeloperoxidase-H2O2-Chloride System of Phagocytes, Covalently Modifies ε-Amino Groups of Protein Lysine Residues
1997
Tissue Destruction by Neutrophils
1989 Standout
Myeloperoxidase-derived Reactive Chlorinating Species from Human Monocytes Target Plasmalogens in Low Density Lipoprotein
2003
Far-red to near infrared analyte-responsive fluorescent probes based on organic fluorophore platforms for fluorescence imaging
2012 Standout
Superoxide enhances hypochlorous acid production by stimulated human neutrophils
1990
Myeloperoxidase-mediated activation of xenobiotics by human leukocytes
1993
p-Hydroxyphenylacetaldehyde, an Aldehyde Generated by Myeloperoxidase, Modifies Phospholipid Amino Groups of Low Density Lipoprotein in Human Atherosclerotic Intima
2000
Phagocytes Produce 5-Chlorouracil and 5-Bromouracil, Two Mutagenic Products of Myeloperoxidase, in Human Inflammatory Tissue
2003
A Fluorescent Probe for the Detection of Myeloperoxidase Activity in Atherosclerosis-Associated Macrophages
2007
Modification of proteins and lipids by myeloperoxidase
1999
3-Chlorotyrosine, a specific marker of myeloperoxidase-catalyzed oxidation, is markedly elevated in low density lipoprotein isolated from human atherosclerotic intima.
1997 Standout
Molecular Chlorine Generated by the Myeloperoxidase-Hydrogen Peroxide-Chloride System of Phagocytes Produces 5-Chlorocytosine in Bacterial RNA
1999
The reactivity of myeloperoxidase compound I formed with hypochlorous acid
2000
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Myeloperoxidase, a catalyst for lipoprotein oxidation, is expressed in human atherosclerotic lesions.
1994
A Tale of Two Controversies
2002
Hypochlorous Acid Oxygenates the Cysteine Switch Domain of Pro-matrilysin (MMP-7)
2001
Regulation of the NADPH-oxidase complex of phagocytic leukocytes. Recent insights from structural biology, molecular genetics, and microscopy
2004
Spectral and Kinetic Studies on the Formation of Myeloperoxidase Compounds I and II: Roles of Hydrogen Peroxide and Superoxide
1994
Early Protein Evolution: Building Domains from Ligand-binding Polypeptide Segments
2006 StandoutNobel
Human Phagocytes Employ the Myeloperoxidase-Hydrogen Peroxide System to Synthesize Dityrosine, Trityrosine, Pulcherosine, and Isodityrosine by a Tyrosyl Radical-dependent Pathway
1996
The elephant in uremia: Oxidant stress as a unifying concept of cardiovascular disease in uremia
2002
Intrinsic peroxidase-like activity of ferromagnetic nanoparticles
2007 Standout
Biosynthesis and processing of myeloperoxidase — A marker for myeloid cell differentiation
1988
Mechanisms for Oxidizing Low-Density Lipoprotein Insights from Patterns of Oxidation Products in the Artery Wall and from Mouse Models of Atherosclerosis
2001
Association Between Myeloperoxidase Levels and Risk of Coronary Artery Disease
2001
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Crystallization and subunit structure of canine myeloperoxidase
1987
The Influence of Superoxide on the Production of Hypochlorous Acid by Human Neutrophils
1991
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Cholesterol Chlorohydrin Synthesis by the Myeloperoxidase-Hydrogen Peroxide-Chloride System: Potential Markers for Lipoproteins Oxidatively Damaged by Phagocytes
1994
A pulse radiolysis investigation of the reactions of myeloperoxidase with superoxide and hydrogen peroxide
1988
The bactericidal effects of the respiratory burst and the myeloperoxidase system isolated in neutrophil cytoplasts
1988
Human neutrophils employ the myeloperoxidase-hydrogen peroxide-chloride system to convert hydroxy-amino acids into glycolaldehyde, 2-hydroxypropanal, and acrolein. A mechanism for the generation of highly reactive alpha-hydroxy and alpha,beta-unsaturated aldehydes by phagocytes at sites of inflammation.
1997
Myeloperoxidase: a key regulator of neutrophil oxidant production
1997
Lysine Residues Direct the Chlorination of Tyrosines in YXXK Motifs of Apolipoprotein A-I When Hypochlorous Acid Oxidizes High Density Lipoprotein
2004
Tetragonal crystals of canine myeloperoxidase suitable for X-ray structural analysis
1989
Heme-thiolate haloperoxidases: versatile biocatalysts with biotechnological and environmental significance
2006
Human Neutrophils Use the Myeloperoxidase-Hydrogen Peroxide-Chloride System to Chlorinate but Not Nitrate Bacterial Proteins during Phagocytosis
2002
Mechanisms of oxidative damage by myeloperoxidase in atherosclerosis and other inflammatory disorders
1999
Myeloperoxidase-generated oxidants and atherosclerosis
2000
Increased atherosclerosis in myeloperoxidase-deficient mice
2001
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Enzymatic functionalization of carbon–hydrogen bonds
2010 StandoutNobel
Nitric Oxide Is a Physiological Substrate for Mammalian Peroxidases
2000
Inflammation in atherosclerosis
2002 StandoutNature
Myeloperoxidase
2000
Macrophage scavenger receptor CD36 is the major receptor for LDL modified by monocyte-generated reactive nitrogen species
2000
Nitrogen dioxide radical generated by the myeloperoxidase‐hydrogen peroxide‐nitrite system promotes lipid peroxidation of low density lipoprotein
1999
Nitric Oxide Modulates the Catalytic Activity of Myeloperoxidase
2000
Reactive oxygen species in cardiovascular disease
2011
The Oxidation of Lipoproteins by Monocytes-Macrophages
1999
Formation of Reactive Nitrogen Species during Peroxidase-catalyzed Oxidation of Nitrite
1997
Contributions of Myeloperoxidase to Proinflammatory Events: More Than an Antimicrobial System
2001
Chlorination of Tyrosyl Residues in Peptides by Myeloperoxidase and Human Neutrophils
1995
X-ray Crystal Structure and Characterization of Halide-binding Sites of Human Myeloperoxidase at 1.8 Å Resolution
2000
The role of oxidized lipoproteins in atherogenesis
1996
Atherosclerosis
2000 StandoutNature
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
2003
Myeloperoxidase-catalyzed 3-chlorotyrosine formation in dialysis patients
2001
Hypochlorous Acid Generated by Myeloperoxidase Modifies Adjacent Tryptophan and Glycine Residues in the Catalytic Domain of Matrix Metalloproteinase-7 (Matrilysin)
2003
Human neutrophils employ chlorine gas as an oxidant during phagocytosis.
1996
Effect of Ultraviolet Radiation on Cataract Formation
1988
Atherosclerosis
2001 Standout
Myeloperoxidase-catalyzed iodination and coupling
1992
Myeloperoxidase and Horseradish Peroxidase Catalyze Tyrosine Nitration in Proteins from Nitrite and Hydrogen Peroxide
1998
Neuronal expression of myeloperoxidase is increased in Alzheimer's disease
2004
Oxidants and antioxidants in the pathogenesis of atherosclerosis: implications for the oxidized low density lipoprotein hypothesis
1998
Human Neutrophils Employ the Myeloperoxidase-Hydrogen Peroxide-Chloride System to Oxidize α-Amino Acids to a Family of Reactive Aldehydes
1998
The myeloperoxidase system of human phagocytes generates Nε-(carboxymethyl)lysine on proteins: a mechanism for producing advanced glycation end products at sites of inflammation
1999
Amino acid sequence of the cytochrome subunit of the photosynthetic reaction centre from the purple bacterium Rhodopseudomonas viridis
1987 StandoutNobel
Atorvastatin in Patients with Type 2 Diabetes Mellitus Undergoing Hemodialysis
2005 Standout
A reversible fluorescence probe based on Se–BODIPY for the redox cycle between HClO oxidative stress and H2S repair in living cells
2012
Myeloperoxidase-dependent effect of amines on functions of isolated neutrophils.
1983
Kidney Disease as a Risk Factor for Development of Cardiovascular Disease
2003 Standout
3d Transition Metals for C–H Activation
2018 Standout
The reductive cleavage of myeloperoxidase in half, producing enzymically active hemi-myeloperoxidase.
1981
Oxidative inactivation of leukotriene C 4 by stimulated human polymorphonuclear leukocytes
1982 StandoutNobel
Control of the redox potential of cytochrome and microscopic dielectric effects in proteins
1986 StandoutNobel
Quantitative and temporal characterization of the extracellular H2O2 pool generated by human neutrophils.
1984
Organic Photoredox Catalysis
2016 Standout
N‐(2‐Oxoacyl)amino Acids and Nitriles as Final Products of Dipeptide Chlorination Mediated by the Myeloperoxidase/H2O2/Cl− System
1978
Mass spectrometric quantification of amino acid oxidation products in proteins: insights into pathways that promote LDL oxidation in the human artery wall
1999
The importance of free radicals and catalytic metal ions in human diseases
1985
Oxygen Metabolism and the Toxic Properties of Phagocytes
1980
Fluorescent Detection of Hypochlorous Acid from Turn‐On to FRET‐Based Ratiometry by a HOCl‐Mediated Cyclization Reaction
2012
Oxygen-Dependent Microbial Killing by Phagocytes
1978 Standout
Neutrophils employ the myeloperoxidase system to generate antimicrobial brominating and chlorinating oxidants during sepsis
2001
Luminescent Chemodosimeters for Bioimaging
2012 Standout
Activation of the NF-κB transcription factor in a T-lymphocytic cell line by hypochlorous acid
1997
Arylamine oxidations by chloroperoxidase
1979
A Single Nanoprobe for Ratiometric Imaging and Biosensing of Hypochlorite and Glutathione in Live Cells Using Surface-Enhanced Raman Scattering
2016
Synthesis, Isolation, and Characterization of the Adduct Formed in the Reaction of p-Hydroxyphenyl- acetaldehyde with the Amino Headgroup of Phosphatidylethanolamine and Phosphatidylserine
1998
Chem-Bioinformatics and QSAR: A Review of QSAR Lacking Positive Hydrophobic Terms
2001 Standout
Thiocyanate and chloride as competing substrates for myeloperoxidase
1997
Oxidation of low-density lipoprotein with hypochlorite causes transformation of the lipoprotein into a high-uptake form for macrophages
1993
Dityrosine, a specific marker of oxidation, is synthesized by the myeloperoxidase-hydrogen peroxide system of human neutrophils and macrophages.
1993
[1] Role of free radicals and catalytic metal ions in human disease: An overview
1990 Standout
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
Surface-Enhanced Raman Spectroscopy for Bioanalysis: Reliability and Challenges
2018 Standout
Purification and some properties of peroxidases of rat bone marrow
1987
Reaction of compound III of myeloperoxidase with ascorbic acid.
1990
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Oxidation of low-density lipoprotein by hypochlorite causes aggregation that is mediated by modification of lysine residues rather than lipid oxidation
1994
Identification of antigen-presenting dendritic cells in mouse aorta and cardiac valves
2009 StandoutNobel
Reversible Near-Infrared Fluorescent Probe Introducing Tellurium to Mimetic Glutathione Peroxidase for Monitoring the Redox Cycles between Peroxynitrite and Glutathione in Vivo
2013 Standout
Selective oxidation in vitro by myeloperoxidase of the N-terminal amine in apolipoprotein B-100
2001
Mass Spectrometric Quantification of Markers for Protein Oxidation by Tyrosyl Radical, Copper, and Hydroxyl Radical in Low Density Lipoprotein Isolated from Human Atherosclerotic Plaques
1997
Oxidative Stress, Caloric Restriction, and Aging
1996 StandoutScience
Modification of Type III VLDL, Their Remnants, and VLDL From ApoE-Knockout Mice by p -Hydroxyphenylacetaldehyde, a Product of Myeloperoxidase Activity, Causes Marked Cholesteryl Ester Accumulation in Macrophages
1999
Oxidative stress and nitration in neurodegeneration: Cause, effect, or association?
2003
Analysis of the peptide subunits of human neutrophil myeloperoxidase
1986
Inflammation and Atherosclerosis
2002 Standout
Vitamin C. Stimulates the chlorinating activity of human myeloperoxidase
1984
Comparison of myeloperoxidase and hemi-myeloperoxidase with respect to catalysis, regulation, and bactericidal activity
1984
Studies on the subunits of human myeloperoxidase
1984
Production of the superoxide adduct of myeloperoxidase (compound III) by stimulated human neutrophils and its reactivity with hydrogen peroxide and chloride
1985
Inside the Neutrophil Phagosome: Oxidants, Myeloperoxidase, and Bacterial Killing
1998
Formation of singlet oxygen by the myeloperoxidase-mediated antimicrobial system.
1977
Eosinophil Peroxidase Catalyzes Bromination of Free Nucleosides and Double-Stranded DNA
2001
The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds
2004 Standout
Role of hydrogen peroxide in neutrophil-mediated destruction of cultured endothelial cells.
1981
The bactericidal effects of the respiratory burst and the myeloperoxidase system isolated in neutrophil cytoplasts
1988
REACTIVE OXYGEN SPECIES: Metabolism, Oxidative Stress, and Signal Transduction
2004 Standout
Purification of myeloperoxidase from equine polymorphonuclear leucocytes.
1998
Distinct chromatographic forms of human hemi-myeloperoxidase obtained by reductive cleavage of the dimeric enzyme. Evidence for subunit heterogeneity.
1990
Cataracts
2017 Standout
Science and technology for water purification in the coming decades
2008 StandoutNature
Comparative reactivities of various biological compounds with myeloperoxidase-hydrogen peroxide-chloride, and similarity of oxidant to hypochlorite
1985
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
Tyrosyl radical generated by myeloperoxidase is a physiological catalyst for the initiation of lipid peroxidation in low density lipoprotein.
1994
Biological reactivity of hypochlorous acid: implications for microbicidal mechanisms of leukocyte myeloperoxidase.
1981
New Perspectives on c-Type Cytochromes
1982
[40] Preparation and characterization of chloramines
1986
Superoxide modulates the activity of myeloperoxidase and optimizes the production of hypochlorous acid
1988
Fluorescent Chemosensors Based on Spiroring-Opening of Xanthenes and Related Derivatives
2011 Standout
Preparation and Characterization of a Polyclonal Antibody against Brominated Protein
2009
A potential role for hypochlorous acid in granulocyte-mediated tumor cell cytotoxicity
1980
Chlorination of endogenous amines by isolated neutrophils. Ammonia-dependent bactericidal, cytotoxic, and cytolytic activities of the chloramines.
1984
Abnormal neutrophil myeloperoxidase from a patient with chronic myelocytic leukemia
1982
Chlorination of Taurine by Human Neutrophils
1982
The Halogen Bond
2016 Standout
Myeloperoxidase produces nitrating oxidants in vivo
2002
Assessment of chlorination by human neutrophils
1983 Nature
Biochemical requirements for singlet oxygen production by purified human myeloperoxidase.
1984
Human Neutrophils Employ Myeloperoxidase To Convert α-Amino Acids to a Battery of Reactive Aldehydes: A Pathway for Aldehyde Generation at Sites of Inflammation
1998
Protein Radicals in Enzyme Catalysis
1998 Standout
Inside the Neutrophil Phagosome: Oxidants, Myeloperoxidase, and Bacterial Killing
1998
8-Nitro-2‘-deoxyguanosine, a Specific Marker of Oxidation by Reactive Nitrogen Species, Is Generated by the Myeloperoxidase−Hydrogen Peroxide−Nitrite System of Activated Human Phagocytes
1999
The aging process.
1981 Standout
Biomimetic Reactivity of Oxygen-Derived Manganese and Iron Porphyrinoid Complexes
2017
Myeloperoxidase-dependent fluorescein chlorination by stimulated neutrophils.
1984
Reaction of Myeloperoxidase Compound I with Chloride, Bromide, Iodide, and Thiocyanate
1998
Isolation and characterization of a cDNA coding for human myeloperoxidase
1987
Generation of Intramolecular and Intermolecular Sulfenamides, Sulfinamides, and Sulfonamides by Hypochlorous Acid: A Potential Pathway for Oxidative Cross-Linking of Low-Density Lipoprotein by Myeloperoxidase
2001
Influence of superoxide on myeloperoxidase kinetics measured with a hydrogen peroxide electrode
1989
Biochemical and Immunologic Analysis of Hereditary Myeloperoxidase Deficiency
1983
Kinetic studies on the reaction of compound II of myeloperoxidase with ascorbic acid. Role of ascorbic acid in myeloperoxidase function.
1990
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Oxidative inactivation of myeloperoxidase released from human neutrophils
1987
Design Strategies for Water-Soluble Small Molecular Chromogenic and Fluorogenic Probes
2013 Standout
Oxygen radical-induced erythrocyte hemolysis by neutrophils. Critical role of iron and lactoferrin.
1985
Myeloperoxidase: friend and foe
2005 Standout
Intracellular singlet oxygen generation by phagocytosing neutrophils in response to particles coated with a chemical trap.
1992
Myeloperoxidase-catalyzed incorporation of amines into proteins: role of hypochlorous acid and dichloramines
1982
Monocyte and granulocyte-mediated tumor cell destruction. A role for the hydrogen peroxide-myeloperoxidase-chloride system.
1982
3-Bromotyrosine and 3,5-Dibromotyrosine Are Major Products of Protein Oxidation by Eosinophil Peroxidase: Potential Markers for Eosinophil-Dependent Tissue Injury in Vivo
1999
A Unique Class of Near-Infrared Functional Fluorescent Dyes with Carboxylic-Acid-Modulated Fluorescence ON/OFF Switching: Rational Design, Synthesis, Optical Properties, Theoretical Calculations, and Applications for Fluorescence Imaging in Living Animals
2011
Co-oxidation of luminol by hypochlorite and hydrogen peroxide implications for neutrophil chemiluminescence
1985
Structure and Chemistry of Cytochrome P450
2005 Standout
Role of monochloramine in the oxidation of erythrocyte hemoglobin by stimulated neutrophils.
1984
Works of J. Schultz being referenced
Cataract Induction in Mice Exposed to Near UV Light
1974
The subunit structure of crystalline canine myeloperoxidase
1977
Studies on the chlorinating activity of myeloperoxidase.
1976 Standout
Myeloperoxidase and singlet oxygen: a reappraisal
1978
The prosthetic group of myeloperoxidase
1975