Standout Papers
Citation Impact
Citing Papers
Telomere Variation in Xenopus laevis
1998
AID Enzyme-Induced Hypermutation in an Actively Transcribed Gene in Fibroblasts
2002 StandoutScienceNobel
Genome analysis of the platypus reveals unique signatures of evolution
2008 Nature
Hallmarks of Cancer: The Next Generation
2011 Standout
Normal telomere maintenance in immortal ataxia telangiectasia cell lines
1997
Finishing the euchromatic sequence of the human genome
2004 StandoutNature
Telomere reduction in human colorectal carcinoma and with ageing
1990 Nature
Assembly and self-association of Oxytricha telomeric nucleoprotein complexes
1989 StandoutNobel
Centromere and kinetochore structure
1992
Hayflick, his limit, and cellular ageing
2000
Characterization of the pufferfish (Fugu) genome as a compact model vertebrate genome
1993 StandoutNatureNobel
Essential role of mouse telomerase in highly proliferative organs
1998 StandoutNatureNobel
The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats
1989
Oxytrichatelomeric nucleoprotein complexes reconstituted with synthetic DNA
1989 StandoutNobel
An in vitro assay for saccharomyces telomerase requires EST1
1995
An alternative pathway for yeast telomere maintenance rescues est1− senescence
1993 StandoutNobel
A genome-wide comparison of recent chimpanzee and human segmental duplications
2005 StandoutNatureNobel
Monovalent cation-induced structure of telomeric DNA: The G-quartet model
1989
A mutant with a defect in telomere elongation leads to senescence in yeast
1989 StandoutNobel
Telomere states and cell fates
2000 StandoutNatureNobel
Pre-meiotic S phase is linked to reductional chromosome segregation and recombination
2001 StandoutNatureNobel
Human telomeres contain at least three types of G–rich repeat distributed non-randomly
1989
Functional Characterization and Developmental Regulation of Mouse Telomerase RNA
1995 StandoutScienceNobel
Effect of monovalent cation-induced telomeric DNA structure on the binding of Oxytricha telomeric protein
1990 Nobel
Extensive telomere repeat arrays in mouse are hypervariable
1990
Molecular cloning of human telomeres in yeast
1989 Nature
Addition of telomere-associated HeT DNA sequences “heals” broken chromosome ends in Drosophila
1990
Drosophila genome project: One-hit coverage in yeast artificial chromosomes
1991
Telomere Length and Telomerase Expression in Atypical Adenomatous Hyperplasia and Small Bronchioloalveolar Carcinoma of the Lung
2007
The roles of telomeres and telomerase in cell life span
1996
Telomeres shorten during ageing of human fibroblasts
1990 StandoutNatureNobel
Telomeres and telomerase: the path from maize, Tetrahymena and yeast to human cancer and aging
2006 StandoutNobel
Stable length polymorphism of up to 260 kb at the tip of the short arm of human chromosome 16
1991
Length of Telomeric Repeats in Neuroblastoma: Correlation with Prognosis and Other Biological Characteristics
1992
SV40 T antigen induced chromosomal changes reflect a process that is both clastogenic and aneuploidogenic and is ongoing throughout neoplastic progression of human fibroblasts
1992
Runaway telomere elongation caused by telomerase RNA gene mutations
1995 StandoutNatureNobel
Programmable RNA recognition and cleavage by CRISPR/Cas9
2014 StandoutNatureNobel
Structure and polymorphism of human telomere-associated DNA
1990
Viable deletions of a telomere from a Drosophila chromosome
1989
Control of telomere growth by interactions of RAP1 with the most distal telomeric repeats
1996 StandoutNatureNobel
Ablation of XRCC2/3 transforms immunoglobulin V gene conversion into somatic hypermutation
2001 Nature
Telomere loss: mitotic clock or genetic time bomb?
1991
Cloning of human telomeres by complementation in yeast
1989 Nature
Loss of telomeric sites in the chromosomes ofMus musculus domesticus (Rodentia: Muridae) during Robertsonian rearrangements
1995
Telomere reduction in giant cell tumor of bone and with aging
1993
Telomere reduction in endometrial adenocarcinoma
1992
Dynamic Imaging of Genomic Loci in Living Human Cells by an Optimized CRISPR/Cas System
2013 Nobel
A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis
1989 StandoutNatureNobel
Fission yeast Taz1 protein is required for meiotic telomere clustering and recombination
1998 StandoutNatureNobel
Developmentally programmed healing of chromosomes by telomerase in tetrahymena
1991 StandoutNobel
A subterminal satellite located adjacent to telomeres in chimpanzees is absent from the human genome
1994
Hypervariable ultra-long telomeres in mice
1990 Nature
In vivo loss of telomeric repeats with age in humans
1991
Isolation and characterization of a human telomere
1989
Telomeric structure in cells with chromosome end associations
1993
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
2001 StandoutNatureNobel
A truncated human chromosome 16 associated with α thalassaemia is stabilized by addition of telomeric repeat (TTAGGG)n
1990 Nature
The evolution of gene expression levels in mammalian organs
2011 StandoutNatureNobel
In vivo alteration of telomere sequences and senescence caused by mutated Tetrahymena telomerase RNAs
1990 StandoutNatureNobel
DNA primase and the replication of the telomeres inOxytricha nova
1989
Members of the olfactory receptor gene family are contained in large blocks of DNA duplicated polymorphically near the ends of human chromosomes
1998
Telomere length predicts replicative capacity of human fibroblasts.
1992 StandoutNobel
Telomere loss in cells treated with cisplatin
1998
Telomere shortening associated with chromosome instability is arrested in immortal cells which express telomerase activity.
1992 StandoutNobel
Telomerase activity in germline and embryonic cells of Xenopus.
1994 StandoutNobel
Dynamics of CRISPR-Cas9 genome interrogation in living cells
2015 StandoutScienceNobel
A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q
1994 StandoutNobel
Telomere structure in Euplotes crassus: characterization of DNA-protein interactions and isolation of a telomere-binding protein.
1990
Many yeast chromosomes lack the telomere-specific Y' sequence.
1989
Sequencing of Saccharomyces telomeres cloned using T4 DNA polymerase reveals two domains.
1990
Introduction of extra telomeric DNA sequences into Saccharomyces cerevisiae results in telomere elongation.
1989
Involvement of the Silencer and UAS Binding Protein RAP1 in Regulation of Telomere Length
1990 Science
The new frontier of genome engineering with CRISPR-Cas9
2014 StandoutScienceNobel
A Xenopus egg factor with DNA-binding properties characteristic of terminus-specific telomeric proteins.
1993
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Identification of a nonprocessive telomerase activity from mouse cells.
1993 StandoutNobel
Two Inactive Fragments of the Integral RNA Cooperate To Assemble Active Telomerase with the Human Protein Catalytic Subunit (hTERT) In Vitro
1999
Changes of telomere lengths in human intracranial tumours
1993
Loss of telomeric DNA during aging of normal and trisomy 21 human lymphocytes.
1993
The beginning of the ends
1989 StandoutNatureNobel
Structure and variability of human chromosome ends.
1990
Structure and Variability of Human Chromosome Ends
1990
Telomerase in Yeast
1995 StandoutScienceNobel
Telomeres: structure and synthesis.
1990 StandoutNobel
Telomeres and Their Synthesis
1990 StandoutScienceNobel
Structure, Recognition, and Processing of Cisplatin−DNA Adducts
1999 Standout
Evidence for a mitotic clock in human hematopoietic stem cells: loss of telomeric DNA with age.
1994
Specific Association of Human Telomerase Activity with Immortal Cells and Cancer
1994 StandoutScience
Telomerase in kinetoplastid parasitic protozoa
1999 StandoutNobel
A low copy number central sequence with strict symmetry and unusual chromatin structure in fission yeast centromere.
1992
Structure of the colcemid-treated PtK1 kinetochore outer plate as determined by high voltage electron microscopic tomography.
1993 StandoutNobel
The RNA Component of Human Telomerase
1995 StandoutScienceNobel
Effects of Reverse Transcriptase Inhibitors on Telomere Length and Telomerase Activity in Two Immortalized Human Cell Lines
1996 StandoutNobel
Telomerase RNAs of different ciliates have a common secondary structure and a permuted template.
1994 Nobel
Functional Evidence for an RNA Template in Telomerase
1990 StandoutScienceNobel
Template Boundary in a Yeast Telomerase Specified by RNA Structure
2000 StandoutScienceNobel
Telomeres: Beginning to Understand the End
1995 Science
Telomeres in the mouse have large inter-chromosomal variations in the number of T 2 AG 3 repeats
1997
Chromosome ends in Drosophila without telomeric DNA sequences.
1990
Restoration of telomeres in human papillomavirus-immortalized human anogenital epithelial cells.
1994
The Complete Nucleotide Sequence of the Human Immunoglobulin Heavy Chain Variable Region Locus
1998 StandoutNobel
Block in Anaphase Chromosome Separation Caused by a Telomerase Template Mutation
1997 StandoutScienceNobel
Structure and function of telomeres
1991 StandoutNatureNobel
Human telomeres are attached to the nuclear matrix.
1992
Telomeres sans frontieres
1990 StandoutNatureNobel
Works of J. Meyne being referenced
Conservation of the human telomere sequence (TTAGGG)n among vertebrates.
1989
The XRCC2 and XRCC3 repair genes are required for chromosome stability in mammalian cells
1999
Cloning human telomeric DNA fragments into Saccharomyces cerevisiae using a yeast-artificial-chromosome vector.
1989
Telomere Staining of Human Chromosomes and the Mechanism of Radiation-Induced Dicentric Formation
1989
Ordered tandem arrangement of chromosomes in the sperm heads of monotreme mammals.
1996
The centromere-kinetochore complex: a repeat subunit model.
1991
A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.
1988 Standout