Standout Papers
Citation Impact
Citing Papers
Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy
2012 StandoutScienceNobel
Formylglycine-generating enzyme binds substrate directly at a mononuclear Cu(I) center to initiate O 2 activation
2019 StandoutNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
The Human SepSecS-tRNA Sec Complex Reveals the Mechanism of Selenocysteine Formation
2009 StandoutScienceNobel
A small-molecule switch for Golgi sulfotransferases
2004 StandoutNobel
The use of mRNA display to select high-affinity protein-binding peptides
2001 StandoutNobel
Crystal Structure of Argonaute and Its Implications for RISC Slicer Activity
2004 Science
Incorporation of azides into recombinant proteins for chemoselective modification by the Staudinger ligation
2001 StandoutNobel
Expansive discovery of chemically diverse structured macrocyclic oligoamides
2024 StandoutScienceNobel
Structural diversity of heparan sulfate binding domains in chemokines
2002
Heparin-Protein Interactions
2002 Standout
Interdomain interactions within the gene 3 protein of filamentous phage
1999 StandoutNobel
The relationship between peptide structure and antibacterial activity
2003
Nicastrin Functions as a γ-Secretase-Substrate Receptor
2005 StandoutNobel
An ion mobility–mass spectrometry investigation of monocyte chemoattractant protein-1
2009
phenix.mr_rosetta: molecular replacement and model rebuilding with Phenix and Rosetta
2012 StandoutNobel
From one amino acid to another: tRNA-dependent amino acid biosynthesis
2008
Inference of Macromolecular Assemblies from Crystalline State
2007 Standout
Three-dimensional structure of human γ-secretase
2014 Nature
The Solution Structures of the Human β-Defensins Lead to a Better Understanding of the Potent Bactericidal Activity of HBD3 against Staphylococcus aureus
2002
Structure of the type IL -asparaginase from the hyperthermophilic archaeonPyrococcus horikoshiiat 2.16 Å resolution
2005
A general method for the unbiased improvement of solution NMR structures by the use of related X-Ray data, the AUREMOL-ISIC algorithm
2006
Structural and biochemical studies of retroviral proteases
2000
Crystal structure of the two N-terminal domains of g3p from filamentous phage fd at 1.9 Å: evidence for conformational lability 1 1Edited by J. M. Thornton
1999
Structure of the Type VI Secretion System Contractile Sheath
2015 StandoutNobel
The changing of the guard: Molecular diversity and rapid evolution of β-defensins
2006
Defensins: antimicrobial peptides of innate immunity
2003 Standout
Peptide ligation and its application to protein engineering
1999
Tumor-infiltrating dendritic cell precursors recruited by a β-defensin contribute to vasculogenesis under the influence of Vegf-A
2004
The road to fully programmable protein catalysis
2022 StandoutNatureNobel
Structure-Activity Relationships in Defensin Dimers
2004
Structure and assembly of filamentous bacteriophages
2014
MicroRNAs: Target Recognition and Regulatory Functions
2009 Standout
Construction of molecular assemblies via docking: Modeling of tetramers with D2 symmetry
2003
β‐Defensins chemoattract macrophages and mast cells but not lymphocytes and dendritic cells: CCR6 is not involved
2007
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
A short history ofSHELX
2007 Standout
Foreign DNA capture during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
Structure of human MIP-3α chemokine
2006
Analysis of the C. elegans Argonaute Family Reveals that Distinct Argonautes Act Sequentially during RNAi
2006 StandoutNobel
Functional Analysis of the α-Defensin Disulfide Array in Mouse Cryptdin-4
2004
High-resolution structure prediction and the crystallographic phase problem
2007 StandoutNatureNobel
Understanding nature's catalytic toolkit
2005
Antimicrobial peptides: pore formers or metabolic inhibitors in bacteria?
2005 Standout
Continuous directed evolution of aminoacyl-tRNA synthetases
2017
Can innate immunity be enhanced to treat microbial infections?
2004
Analysis and Separation of Residues Important for the Chemoattractant and Antimicrobial Activities of β-Defensin 3
2008 StandoutNobel
Compositional engineering of perovskite materials for high-performance solar cells
2015 StandoutNature
Identification and Biological Characterization of Mouse β-Defensin 14, the Orthologue of Human β-Defensin 3
2008
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Mutational Analysis of the Fractalkine Chemokine Domain
2001
Retroviral Integrases Promote Fraying of Viral DNA Ends
2011
Recent advances in magic angle spinning solid state NMR of membrane proteins
2014
The CC chemokine CCL20 and its receptor CCR6
2003
Structure determination of human and murine β‐defensins reveals structural conservation in the absence of significant sequence similarity
2001
Isolation and Characterization of Human μ-Defensin-3, a Novel Human Inducible Peptide Antibiotic
2001
Mammalian defensins in the antimicrobial immune response
2005 Standout
Does NMR Mean “Not for Molecular Replacement”? Using NMR-Based Search Models to Solve Protein Crystal Structures
2000
Primate defensins
2004
Filamentous phage are released from the bacterial membrane by a two-step mechanism involving a short C-terminal fragment of pIII 1 1Edited by M. Gottesman
1999
Site-specific polymer modification of therapeutic proteins
2005
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
Combinatorial protein reagents to manipulate protein function
2000
Validation of protein models from Cα coordinates alone
1997
Multidimensional signatures in antimicrobial peptides
2004
Accurate design of megadalton-scale two-component icosahedral protein complexes
2016 StandoutScienceNobel
Prediction of the structure of symmetrical protein assemblies
2007 StandoutNobel
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Conformational Preferences of Linear β-Defensins Are Revealed by Ion Mobility-Mass Spectrometry
2010 StandoutNobel
Structure of the STRA6 receptor for retinol uptake
2016 StandoutScienceNobel
β-Defensins in Lung Host Defense
2002
Covalent Dimer Species of β-Defensin Defr1 Display Potent Antimicrobial Activity against Multidrug-Resistant Bacterial Pathogens
2007
Defective lymphocyte chemotaxis in β-arrestin2- and GRK6-deficient mice
2002 StandoutNobel
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Chemical Glycobiology
2001 StandoutScienceNobel
Characterisation of DEFB107 by mass spectrometry: Lessons from an anti-antimicrobial defensin
2006
IL-17 and Th17 Cells
2009 Standout
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
Coot: model-building tools for molecular graphics
2004 Standout
Advances, Interactions, and Future Developments in the CNS, Phenix, and Rosetta Structural Biology Software Systems
2013 StandoutNobel
A bacterial Argonaute with noncanonical guide RNA specificity
2016 StandoutNobel
High thermodynamic stability of parametrically designed helical bundles
2014 StandoutScienceNobel
Site-specific chemical modification of recombinant proteins produced in mammalian cells by using the genetically encoded aldehyde tag
2009 StandoutNobel
Synthesis of Native Proteins by Chemical Ligation
2000
Accurate protein structure modeling using sparse NMR data and homologous structure information
2012 StandoutNobel
Update 1 of: Proteases Universally Recognize Beta Strands In Their Active Sites
2010
The NMR–Rosetta capsid model of M13 bacteriophage reveals a quadrupled hydrophobic packing epitope
2015 StandoutNobel
The hydrogen bond and crystal engineering
1993 Standout
Interface engineering of highly efficient perovskite solar cells
2014 StandoutScience
Receptor-mediated dimerization of JAK2 FERM domains is required for JAK2 activation
2018
Artificial β-defensin based on a minimal defensin template
2009
Structure−Activity Relation of Human β-Defensin 3: Influence of Disulfide Bonds and Cysteine Substitution on Antimicrobial Activity and Cytotoxicity
2005
Differential Regulation of β-Defensin Expression in Human Skin by Microbial Stimuli
2005
A chemical approach to unraveling the biological function of the glycosylphosphatidylinositol anchor
2007 StandoutNobel
The Androgen-Regulated Epididymal Sperm-Binding Protein, Human β-Defensin 118 (DEFB118) (Formerly ESC42), Is an Antimicrobial β-Defensin
2004
Structural insight into TRPV5 channel function and modulation
2019 StandoutNobel
Polysialic acid governs T-cell development by regulating progenitor access to the thymus
2009 StandoutNobel
Structural basis for Zika envelope domain III recognition by a germline version of a recurrent neutralizing antibody
2020 StandoutNobel
REGULATION OF PROTEIN FUNCTION BY GLYCOSAMINOGLYCANS—AS EXEMPLIFIED BY CHEMOKINES
2003
Filamentous Phage Display in the New Millennium
2005
Chemical Synthesis of Lymphotactin: A Glycosylated Chemokine with a C-Terminal Mucin-Like Domain
2001 StandoutNobel
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Comparative Studies on Retroviral Proteases: Substrate Specificity
2010
Works of J. Łubkowski being referenced
Engineering disulfide bridges to dissect antimicrobial and chemotactic activities of human β-defensin 3
2003
Do bacterial l-asparaginases utilize a catalytic triad Thr-Tyr-Glu?
2001
Resonance Assignment and Three-Dimensional Structure Determination of a Human α-Defensin, HNP-1, by Solid-State NMR
2010
The Structure of Human β-Defensin-1
2001
The Structure of Human Macrophage Inflammatory Protein-3α/CCL20
2002
Human Defensins: Synthesis and Structural Properties
2007
The structure of MCP-1 in two crystal forms provides a rare example of variable quaternary interactions
1997
The structural basis of phage display elucidated by the crystal structure of the N-terminal domains of g3p
1998
Total chemical synthesis and high-resolution crystal structure of the potent anti-HIV protein AOP-RANTES
1999
Human β-defensins
2006
Refined crystal structure of Acinetobacter glutaminasificans glutaminase–asparaginase
1994
Toward a universal inhibitor of retroviral proteases: Comparative analysis of the interactions of LP‐130 complexed with proteases from HIV‐1, FIV, and EIAV
1998
A covalently bound catalytic intermediate in Escherichia coli asparaginase : Crystal structure of a Thr‐89‐Val mutant
1996
Atomic resolution structure ofErwinia chrysanthemiL -asparaginase
2002
Structural Characterization of Pseudomonas 7A Glutaminase-Asparaginase
1994
Filamentous phage infection: crystal structure of g3p in complex with its coreceptor, the C-terminal domain of TolA
1999
Structure of an inhibitor complex of the proteinase from feline immunodeficiency virus
1995
Decamers observed in the crystals of bovine pancreatic trypsin inhibitor
1999
Synthesis and characterization of human α ‐defensins 4‐6
2004
Crystal Structure and Amino Acid Sequence of Wolinella Succinogenesl ‐Asparaginase
1996
Crystal Structure of a Complex of the Intracellular Domain of Interferon λ Receptor 1 (IFNLR1) and the FERM/SH2 Domains of Human JAK1
2016
The Crystal Structure of the Chemokine Domain of Fractalkine Shows a Novel Quaternary Arrangement
2000
Studies of the Biological Properties of Human β-Defensin 1
2006
Crystal structure of XMRV protease differs from the structures of other retropepsins
2011 StandoutNobel
The oligomerization domain of p53: Crystal structure of the trigonal form
1996
The Structure of Human β-Defensin-2 Shows Evidence of Higher Order Oligomerization
2000
Electrostatic energy in chloride salts of mononitrogen organic bases
1991
Atomic Resolution Structures of the Core Domain of Avian Sarcoma Virus Integrase and Its D64N Mutant,
1999
Crystal Structures of the Inactive D30N Mutant of Feline Immunodeficiency Virus Protease Complexed with a Substrate and an Inhibitor,
1997
Structure of the catalytic domain of avian sarcoma virus integrase with a bound HIV-1 integrase-targeted inhibitor
1998
Many chemokines including CCL20/MIP-3α display antimicrobial activity
2003
Structural Basis for the Activity and Substrate Specificity of Erwinia chrysanthemi l -Asparaginase,
2001
Antimicrobial Characterization of Human β-Defensin 3 Derivatives
2003
From pro defensins to defensins: synthesis and characterization of human neutrophil pro α‐defensin‐1 and its mature domain
2003
Thermal properties, thermolysis and thermochemistry of alkanaminium iodides
1990
A Remote Arene-Binding Site on Prostate Specific Membrane Antigen Revealed by Antibody-Recruiting Small Molecules
2010
The crystal structure of met-rantes: comparison with native rantes and aop-rantes
2000
Multiple Roles of Antimicrobial Defensins, Cathelicidins, and Eosinophil-Derived Neurotoxin in Host Defense
2004