Citation Impact
Citing Papers
A "Silent" Polymorphism in the MDR 1 Gene Changes Substrate Specificity
2006 StandoutScience
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
MRP2 (ABCC2) transports taxanes and confers paclitaxel resistance and both processes are stimulated by probenecid
2005
Analysis of methotrexate and folate transport by multidrug resistance protein 4 (ABCC4): MRP4 is a component of the methotrexate efflux system.
2002
Multidrug resistance proteins MRP3, MRP1, and MRP2 in lung cancer: correlation of protein levels with drug response and messenger RNA levels.
2001
Expression of human MRP6, a homologue of the multidrug resistance protein gene MRP1, in tissues and cancer cells.
1999
Transport of amphipathic anions by human multidrug resistance protein 3.
2000
Expression of multidrug resistance protein-related genes in lung cancer: correlation with drug response.
1999
Overexpression of the ATP-binding cassette half-transporter, ABCG2 (Mxr/BCrp/ABCP1), in flavopiridol-resistant human breast cancer cells.
2001
The catalytic cycle of P‐glycoprotein
1995
P-glycoprotein and multidrug resistance protein activities in relation to treatment outcome in acute myeloid leukemia.
2000
The MRP family of drug efflux pumps
2003
Treatment with inhibitors of caspases, that are substrates of drug transporters, selectively permits chemotherapy-induced apoptosis in multidrug-resistant cells but protects normal cells
2001
Expression of multidrug resistance protein-3 (multispecific organic anion transporter-D) in human embryonic kidney 293 cells confers resistance to anticancer agents.
1999
Tissue and Cell Distribution of the Multidrug Resistance-Associated Protein (MRP) in Mouse Intestine and Kidney
1999
High expression of MDR1, MRP1, and MRP3 in the hepatic progenitor cell compartment and hepatocytes in severe human liver disease
2003
A Family of Drug Transporters: the Multidrug Resistance-Associated Proteins
2000
Reduced drug accumulation and multidrug resistance in human breast cancer cells without associated P-glycoprotein or MRP overexpression
1997
Inhibition of endosomal sequestration of basic anticancer drugs: influence on cytotoxicity and tissue penetration
2006
Functional Multidrug Resistance Protein (MRP1) Lacking the N-terminal Transmembrane Domain
1998
Induction ofMRP/GS-X pump and cellular resistance to anticancer prostaglandins
1996 StandoutNobel
A canalicular multispecific organic anion transporter (cMOAT) antisense cDNA enhances drug sensitivity in human hepatic cancer cells.
1997
Coordinated Induction of / Pump and γ-Glutamylcysteine Synthetase by Heavy Metals in Human Leukemia Cells
1996
Analysis of the Drug Resistance Profile of Multidrug Resistance Protein 7 (ABCC10)
2004
ATP-dependent 17β-Estradiol 17-(β-D-Glucuronide) Transport by Multidrug Resistance Protein (MRP)
1996
Reversal of a novel multidrug resistance mechanism in human colon carcinoma cells by fumitremorgin C.
1998
Mutation of Trp1254 in the Multispecific Organic Anion Transporter, Multidrug Resistance Protein 2 (MRP2) (ABCC2), Alters Substrate Specificity and Results in Loss of Methotrexate Transport Activity
2001
Phase I and pharmacokinetic study of paclitaxel in combination with biricodar, a novel agent that reverses multidrug resistance conferred by overexpression of both MDR1 and MRP.
1998
ATP-Dependent Efflux of CPT-11 and SN-38 by the Multidrug Resistance Protein (MRP) and Its Inhibition by PAK-104P
1999
Multidrug resistance in cancer: role of ATP–dependent transporters
2002 Standout
Multidrug resistance proteins: role of P-glycoprotein, MRP1, MRP2, and BCRP (ABCG2) in tissue defense
2004
Quantitative reverse transcriptase-polymerase chain reaction measured expression of MDR1 and MRP in primary breast carcinoma.
1998
Simultaneous Activity of MRP1 and Pgp Is Correlated With In Vitro Resistance to Daunorubicin and With In Vivo Resistance in Adult Acute Myeloid Leukemia
1999
Human Multidrug Resistance Associated Protein 4 Confers Resistance to Camptothecins
2005
Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: a Southwest Oncology Group Study.
1999
pABC11 (Also Known as MOAT-C and MRP5), a Member of the ABC Family of Proteins, Has Anion Transporter Activity but Does Not Confer Multidrug Resistance When Overexpressed in Human Embryonic Kidney 293 Cells
1999
Characterization of the drug resistance and transport properties of multidrug resistance protein 6 (MRP6, ABCC6).
2002
Structural, mechanistic and clinical aspects of MRP1
1999
Immunohistochemical detection of multidrug resistance protein in human lung cancer and normal lung.
1998
Characterization of Drug Transport by the Human Multidrug Resistance Protein 3 (ABCC3)
2001
Congenital Jaundice in Rats with a Mutation in a Multidrug Resistance-Associated Protein Gene
1996 Science
Increased sensitivity to anticancer drugs and decreased inflammatory response in mice lacking the multidrug resistance-associated protein
1997
ATP‐ and glutathione‐dependent transport of chemotherapeutic drugs by the multidrug resistance protein MRP1
1999
Basolateral localization and export activity of the human multidrug resistance-associated protein in polarized pig kidney cells.
1996
Drug Resistance and ATP-Dependent Conjugate Transport Mediated by the Apical Multidrug Resistance Protein, MRP2, Permanently Expressed in Human and Canine Cells
1999
MRP3, an organic anion transporter able to transport anti-cancer drugs
1999
Diagnostics of multidrug resistance in cancer
1998
The multidrug-resistant phenotype associated with overexpression of the new ABC half-transporter, MXR (ABCG2)
2000
MRP and MDR1 gene expression in primary breast carcinomas.
1996
Drug Resistance-Associated Marker Lrp for Prediction of Response to Chemotherapy and Prognoses in Advanced Ovarian Carcinoma
1995
Families of arsenic transporters
1999
Comparison of the Functional Characteristics of the Nucleotide Binding Domains of Multidrug Resistance Protein 1
2000
Multidrug Resistance in Breast Cancer: a Meta-analysis of MDR1/gp170 Expression and Its Possible Functional Significance
1997
Transport of the β-O-Glucuronide Conjugate of the Tobacco-specific Carcinogen 4-(Methylnitrosamino)-1-(3-pyridyl)-1-butanol (NNAL) by the Multidrug Resistance Protein 1 (MRP1)
2001
Molecular identification of a renal urate–anion exchanger that regulates blood urate levels
2002 StandoutNature
Positively Cooperative Sites for Drug Transport by P‐Glycoprotein with Distinct Drug Specificities
1997
A view on drug resistance in cancer
2019 StandoutNature
ABC-ATPases, adaptable energy generators fuelling transmembrane movement of a variety of molecules in organisms from bacteria to humans
1999
Biasing the content of hippocampal replay during sleep
2012
Repopulation of cancer cells during therapy: an important cause of treatment failure
2005
Phase I crossover study of paclitaxel with r-verapamil in patients with metastatic breast cancer.
1996
Cyclosporins as drug resistance modifiers
1992
Complete in vivo reversal of P‐glycoprotein pump function in the blood‐brain barrier visualized with positron emission tomography
1998
Tissue Distribution and Induction of Human Multidrug Resistant Protein 3
2002
Conjugate export pumps of the multidrug resistance protein (MRP) family: localization, substrate specificity, and MRP2-mediated drug resistance
1999
Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
1993 Standout
Multidrug resistance protein 1 protects the choroid plexus epithelium and contributes to the blood-cerebrospinal fluid barrier
2000
A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome
1997
Differential and Simultaneous Adenosine Di- and Triphosphate Binding by MutS
2003 StandoutNobel
Hydrolytically Deficient MutS E694A Is Defective in the MutL-dependent Activation of MutH and in the Mismatch-dependent Assembly of the MutS · MutL · Heteroduplex Complex
2003 StandoutNobel
Drug penetration in solid tumours
2006 Standout
The value of the MDR1 reversal agent PSC-833 in addition to daunorubicin and cytarabine in the treatment of elderly patients with previously untreated acute myeloid leukemia (AML), in relation to MDR1 status at diagnosis
2005
Hepatobiliary secretion of organic compounds; molecular mechanisms of membrane transport
1995
Overlapping substrate specificities and tissue distribution of cytochrome P450 3A and P‐glycoprotein: Implications for drug delivery and activity in cancer chemotherapy
1995
The C. elegans Cell Corpse Engulfment Gene ced-7 Encodes a Protein Similar to ABC Transporters
1998 StandoutNobel
Human-level control through deep reinforcement learning
2015 StandoutNatureNobel
Metabolism and action of amino acid analog anti-cancer agents
1990
Allosteric Interactions between the Two Non-equivalent Nucleotide Binding Domains of Multidrug Resistance Protein MRP1
2000
The memory function of sleep
2010 Standout
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
Analysis of the MRP4 Drug Resistance Profile in Transfected NIH3T3 Cells
2000
A functional assay for detection of the mitoxantrone resistance protein, MXR (ABCG2)
2001
Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer
2004 Standout
The Yeast Cadmium Factor Protein (YCF1) Is a Vacuolar Glutathione S-Conjugate Pump
1996
Circadian Expression of Clock Genes in Human Oral Mucosa and Skin
2001
Transport properties of the multidrug resistance‐associated protein (MRP) in human tumour cells
1996
99mTc-sestamibi is a substrate for P-glycoprotein and the multidrug resistance-associated protein
1998
Reversal of multidrug resistance by B859-35, a metabolite of B859-35, niguldipine, verapamil and nitrendipine
1992
Transport of Cyclic Nucleotides and Estradiol 17-β-d-Glucuronide by Multidrug Resistance Protein 4
2001
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Targeting multidrug resistance in cancer
2006 Standout
Expression of P-Glycoprotein in High-Grade Osteosarcomas in Relation to Clinical Outcome
1995
The biology of the P-glycoproteins
1995
Effect of Multidrug Resistance-Reversing Agents on Transporting Activity of Human Canalicular Multispecific Organic Anion Transporter
1999
Expression Cloning and Characterization of a Novel Multispecific Organic Anion Transporter
1997
Malignant Gliomas in Adults
2008 Standout
Preferential expression and activity of multidrug resistance gene 1 product (P-glycoprotein), a functionally active efflux pump, in human CD8 + T cells: A role in cytotoxic effector function
1992
Incidence of P-glycoprotein overexpression and multidrug resistance (MDR) reversal in adult soft tissue sarcoma
2000
The Human ATP-Binding Cassette (ABC) Transporter Superfamily
2001
Drug target validation and identification of secondary drug target effects using DNA microarrays
1998 StandoutNobel
Examination by laser scanning confocal fluorescence imaging microscopy of the subcellular localisation of anthracyclines in parent and multidrug resistant cell lines
1993
Meta-analysis of radiation therapy with and without adjuvant chemotherapy for malignant gliomas in adults
1993
P-glycoprotein expression at diagnosis may not be a primary mechanism of therapeutic failure in childhood rhabdomyosarcoma.
1996
From MDR to MXR: new understanding of multidrug resistance systems, their properties and clinical significance
2001
Imaging Dynamic Redox Changes in Mammalian Cells with Green Fluorescent Protein Indicators
2004 StandoutNobel
Biochemistry of arsenic detoxification
2002
Interactions of the Human Multidrug Resistance Proteins MRP1 and MRP2 with Organic Anions
2000
Calcein assay for multidrug resistance reliably predicts therapy response and survival rate in acute myeloid leukaemia
2001
Flow Cytometric Measurement of Functional and Phenotypic P-Glycoprotein
2005
Pharmacological considerations in the modulation of multidrug resistance
1996
Relationships between carboplatin exposure and tumor response and toxicity in patients with ovarian cancer.
1992 Standout
Multidrug resistance related molecules in human and murine lung
2002
Expression of the multidrug resistance-associated protein (MRP) gene in primary non-small-cell lung cancer
1996
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
2003 Standout
Drug export activity of the human canalicular multispecific organic anion transporter in polarized kidney MDCK cells expressing cMOAT (MRP2) cDNA.
1998
Differential Specificities and Simultaneous Occupancy of Human MutSα Nucleotide Binding Sites
2004 StandoutNobel
Inhibitory effect of the reversal agents V-104, GF120918 and Pluronic L61 on MDR1 Pgp-, MRP1- and MRP2-mediated transport
2000
The prognostic significance of expression of the multidrug resistance-associated protein (MRP) in primary breast cancer
1997
Sequence-dependent growth inhibition and DNA damage formation by the irinotecan–5-fluorouracil combination in human colon carcinoma cell lines
1999
Intratumor distribution of doxorubicin following i.v. administration of drug encapsulated in egg phosphatidylcholine/cholesterol liposomes
1997
MDR3 P-glycoprotein, a Phosphatidylcholine Translocase, Transports Several Cytotoxic Drugs and Directly Interacts with Drugs as Judged by Interference with Nucleotide Trapping
2000
ABC transporters in lipid transport
2000
NF-κB functions as a tumour promoter in inflammation-associated cancer
2004 StandoutNature
Transport of glutathione prostaglandin A conjugates by the multidrug resistance protein 1
1997
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
2003 StandoutNature
MOAT-E (ARA) is a full-length MRP/cMOAT subfamily transporter expressed in kidney and liver
1999
Improving Penetration in Tumors With Nanoassemblies of Phospholipids and Doxorubicin
2007
Development of Multidrug-Resistance Convertors: Sense or Nonsense?
2000
Buthionine sulphoximine-mediated sensitisation of etoposide-resistant human breast cancer MCF7 cells overexpressing the multidrug resistance-associated protein involves increased drug accumulation
1995
Angiogenesis as a therapeutic target
2005 StandoutNature
Multidrug Resistance Protein (MRP)-mediated Transport of Leukotriene C4 and Chemotherapeutic Agents in Membrane Vesicles
1996
The reversal of multidrug resistance: an update
2003
Drug Resistance and the Solid Tumor Microenvironment
2007 Standout
Decreased accumulation of [14c]carboplatin in human cisplatin-resistant cells results from reduced energy-dependent uptake
2000
Multidrug Resistance Protein 1 (MRP1, ABCC1) Mediates Resistance to Mitoxantrone via Glutathione-Dependent Drug Efflux
2006
Camptothecins: from bench research to hospital wards.
1994
Expression of the MRP gene-encoded conjugate export pump in liver and its selective absence from the canalicular membrane in transport-deficient mutant hepatocytes.
1995
The Role of ABC Transporters in Clinical Practice
2003
Mammalian drug efflux transporters of the ATP binding cassette (ABC) family: an overview
2012 Standout
Anti-cancer-prostaglandin-induced cell-cycle arrest and its modulation by an inhibitor of the ATP-dependent glutathione S-conjugate export pump (GS-X pump)
1998 StandoutNobel
Association of CYP 3 A 4 genotype with treatment-related leukemia
1998
Breast Cancer Resistance Protein in Drug Resistance of Primitive CD34+38− Cells in Acute Myeloid Leukemia
2005
Antifolate resistance mediated by the multidrug resistance proteins MRP1 and MRP2.
1999
Isolation of MOAT-B, a widely expressed multidrug resistance-associated protein/canalicular multispecific organic anion transporter-related transporter.
1998
The E23 early gene of Drosophila encodes an ecdysone-inducible ATP-binding cassette transporter capable of repressing ecdysone-mediated gene activation
2000
FOLFIRINOX versus Gemcitabine for Metastatic Pancreatic Cancer
2011 Standout
Nuclear Receptors and Lipid Physiology: Opening the X-Files
2001 StandoutScience
Levels of multidrug resistance (MDR1) P-glycoprotein expression by human breast cancer correlate with in vitro resistance to taxol and doxorubicin.
1998
The multidrug resistance (mdr1) gene product functions as an ATP channel.
1993
Arsenite transport by mammalian aquaglyceroporins AQP7 and AQP9
2002 StandoutNobel
Hydrogels for Tissue Engineering
2001 Standout
Polymersomes: Tough Vesicles Made from Diblock Copolymers
1999 StandoutScience
Interaction of an alkylating camptothecin derivative with a DNA base at topoisomerase I-DNA cleavage sites.
1995 StandoutNobel
DAF-16 Target Genes That Control C. elegans Life-Span and Metabolism
2003 StandoutScienceNobel
Genistein activates CFTR Cl- channels via a tyrosine kinase- and protein phosphatase-independent mechanism
1997
Characterization of the human MDR3 P-glycoprotein and its recognition by P-glycoprotein-specific monoclonal antibodies.
1991
Phytoestrogens: epidemiology and a possible role in cancer protection.
1995 Standout
Genetic Separation of FK506 Susceptibility and Drug Transport in the Yeast Pdr5 ATP-binding Cassette Multidrug Resistance Transporter
1998
Involvement of P-glycoprotein in the transmembrane transport of interleukin-2 (IL-2), IL-4, and interferon-gamma in normal human T lymphocytes
1996
In vitro and in vivo reversal of P-glycoprotein-mediated multidrug resistance by a novel potent modulator, XR9576.
2001
Mammalian ABC Transporters in Health and Disease
2002
Control of skin cancer by the circadian rhythm
2011 StandoutNobel
Characterization of Acidic Vesicles in Multidrug-resistant and Sensitive Cancer Cells by Acridine Orange Staining and Confocal Microspectrofluorometry
1997
Multidrug Resistance Protein 1 Protects the Oropharyngeal Mucosal Layer and the Testicular Tubules against Drug-induced Damage
1998
Limited penetration of anticancer drugs through tumor tissue: a potential cause of resistance of solid tumors to chemotherapy.
2002
Multiple mechanisms confer drug resistance to mitoxantrone in the human 8226 myeloma cell line.
1999
The Ecology of Arsenic
2003 StandoutScience
About Sleep's Role in Memory
2013 Standout
Expression of the multidrug resistance-associated protein (MRP) gene in human cancers.
1995
Choroid plexus epithelial expression of MDR 1 P glycoprotein and multidrug resistance-associated protein contribute to the blood–cerebrospinal-fluid drug-permeability barrier
1999
Multistage nanoparticle delivery system for deep penetration into tumor tissue
2011 StandoutNobel
The Effects of Plant Flavonoids on Mammalian Cells:Implications for Inflammation, Heart Disease, and Cancer
2000 Standout
Detection of in vivo P-glycoprotein inhibition by PSC 833 using Tc-99m sestamibi.
1997
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
2009 StandoutScience
Hypersensitization of Multidrug Resistant Human Ovarian Carcinoma Cells by Pluronic P85 Block Copolymer
1996
A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels
1998 StandoutNobel
Fumitremorgin C reverses multidrug resistance in cells transfected with the breast cancer resistance protein.
2000
Enzymatic aminoacylation of tRNA with unnatural amino acids
2006 StandoutNobel
P-Glycoprotein, a gatekeeper in the blood–brain barrier
1999
The Distribution of the Anticancer Drug Doxorubicin in Relation to Blood Vessels in Solid Tumors
2005
Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics
1999 StandoutScience
Multiple event activation of a generic prodrug trigger by antibody catalysis
1999 StandoutNobel
Overexpression of the gene encoding the multidrug resistance-associated protein results in increased ATP-dependent glutathione S-conjugate transport.
1994
Transmembrane Inhibitors of P-Glycoprotein, an ABC Transporter
2005
Characterization of vincristine transport by the M(r) 190,000 multidrug resistance protein (MRP): evidence for cotransport with reduced glutathione.
1998
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Multidrug-resistance protein 5 is a multispecific organic anion transporter able to transport nucleotide analogs
2000
Pharmacological characterization of multidrug resistant MRP-transfected human tumor cells.
1994
Phase I and Pharmacokinetic Study of the Novel MDR1 and MRP1 Inhibitor Biricodar Administered Alone and in Combination With Doxorubicin
2001
ATP transduces signals from ASGM1, a glycolipid that functions as a bacterial receptor
2001 StandoutNobel
Mice with homozygous disruption of the mdr2 P-glycoprotein gene. A novel animal model for studies of nonsuppurative inflammatory cholangitis and hepatocarcinogenesis.
1994
Overexpression of the BCRP/MXR/ABCP gene in a topotecan-selected ovarian tumor cell line.
1999
Specific detection of multidrug resistance proteins MRP1, MRP2, MRP3, MRP5, and MDR3 P-glycoprotein with a panel of monoclonal antibodies.
2000
Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line
1992 StandoutScience
Quinine as a multidrug resistance inhibitor: a phase 3 multicentric randomized study in adult de novo acute myelogenous leukemia
2003
Genistein activates CFTR-mediated Cl−secretion in the murine trachea and colon
2000 StandoutNobel
Chemical Implications for Antitumor and Antiviral Prostaglandins: Reaction of Δ7-Prostaglandin A1 and Prostaglandin A1 Methyl Esters with Thiols
1997 StandoutNobel
Works of J. Lankelma being referenced
Anthracyclines modulate multidrug resistance protein (MRP) mediated organic anion transport
1997
Potent interaction of flavopiridol with MRP1
1999
Modulation by (iso)flavonoids of the ATPase activity of the multidrug resistance protein
1997
How to probe clinical tumour samples for p-glycoprotein and multidrug resistance-associated protein
1996
Theoretical and practical considerations for the measurement of P-glycoprotein function in acute myeloid leukemia
1997
Preferential Reactivation of Motivationally Relevant Information in the Ventral Striatum
2008
Do P-glycoprotein and major vault protein (MVP/LRP) expression correlate with in vitro daunorubicin resistance in acute myeloid leukemia?
1999
Genistein modulates the decreased drug accumulation in non-P-glycoprotein mediated multidrug resistant tumour cells
1993
Formation of different reaction products with single- and double-stranded DNA by the ortho-quinone and the semi-quinone free radical of etoposide (VP-16-213)
1991
P-glycoprotein drug efflux pump involved in the mechanisms of intrinsic drug resistance in various colon cancer cell lines
1991
Reactions of glutathione with the catechol, the ortho-quinone and the semi-quinone free radical of etoposide Consequences for DNA inactivation
1992
P-glycoprotein in primary acute myeloid leukemia and treatment outcome of idarubicin/cytosine arabinoside-based induction therapy
2000
Modulation by d,l-buthionine-S,R-sulphoximine of etoposide cytotoxicity on human non-small cell lung, ovarian and breast carcinoma cell lines
1992
Cortisol is transported by the multidrug resistance gene product P-glycoprotein
1993
Monoclonal antibody JSB‐1 detects a highly conserved epitope on the P‐glycoprotein associated with multi‐drug‐resistance
1988
Quantitative Determination of Factors Contributing to Doxorubicin Resistance in Multidrug-Resistant Cells
1989
Highly sensitive and specific detection of P-glycoprotein function for haematological and solid tumour cells using a novel nucleic acid stain
1997
Daunorubicin efflux against a concentration gradient in non‐P‐glycoprotein multidrug‐resistant lung‐cancer cells
1994
Correlation between functional and molecular analysis of mdr1 P‐glycoprotein in human solid‐tumor xenografts
1995
The polyoxyethylene castor oil Cremophor EL modifies multidrug resistance
1990
Functional detection of MDR1/P170 and MRP/P190-mediated multidrug resistance in tumour cells by flow cytometry
1995
Cyclosporin A and verapamil have different effects on energy metabolism in multidrug-resistant tumour cells
1990
Vinblastine and sulfinpyrazone export by the multidrug resistance protein MRP2 is associated with glutathione export
2000
Changes in subcellular doxorubicin distribution and cellular accumulation alone can largely account for doxorubicin resistance in SW-1573 lung cancer and MCF-7 breast cancer multidrug resistant tumour cells
1993
Early multidrug resistance, defined by changes in intracellular doxorubicin distribution, independent of P-glycoprotein
1991
Competitive inhibition by genistein and ATP dependence of daunorubicin transport in intact MRP overexpressing human small cell lung cancer cells
1994
The human multidrug resistance-associated protein MRP is a plasma membrane drug-efflux pump.
1994
Role of glutathione in the export of compounds from cells by the multidrug-resistance-associated protein.
1995
Distribution of multi-drug resistance-associated P-glycoprotein in normal and neoplastic human tissues
1990
Quality control of multidrug resistance assays in adult acute leukemia: correlation between assays for P-glycoprotein expression and activity
1996
Correlation of multidrug resistance with decreased drug accumulation, altered subcellular drug distribution, and increased P-glycoprotein expression in cultured SW-1573 human lung tumor cells
1990
Energy-dependent processes involved in reduced drug accumulation in multidrug-resistant human lung cancer cell lines without P-glycoprotein expression
1992
Cooperative P‐glycoprotein mediated daunorubicin transport into DNA‐loaded plasma membrane vesicles
1994
Role of the semi-quinone free radical of the anti-tumour agent etoposide (VP-16-213) in the inactivation of single- and double-stranded ΦX174 DNA
1990
Daunomycin accumulation in resistant tumor cells as a screening model for resistance modifying drugs: Role of protein binding
1987
Doxorubicin gradients in human breast cancer.
1999
Diurnal variation in the therapeutic efficacy of 5-fluorouracil against murine colon cancer.
1992
Concentrations of N-(Phosphonacetyl)-l-aspartate (PALA) in plasma and tears in man
1981
Methotrexate cytotoxicity: studies on its reversal by folates and nucleosides.
1981
Pharmacokinetics of 5-fluorouracil assessed with a sensitive mass spectrometric method in patients on a dose escalation schedule.
1988