Citation Impact
Citing Papers
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
2018 StandoutNobel
Discovery of a New Bacterial Polyketide Biosynthetic Pathway
2001
Structures of MLSBK Antibiotics Bound to Mutated Large Ribosomal Subunits Provide a Structural Explanation for Resistance
2005 StandoutNobel
Engineering natural products using combinatorial biosynthesis and biocatalysis
2008
The diversity of naturally produced organohalogens
2003
Trends in Antimicrobial Drug Development: Implications for the Future
2004
The Structures of Four Macrolide Antibiotics Bound to the Large Ribosomal Subunit
2002 StandoutNobel
RNA, the first macromolecular catalyst: the ribosome is a ribozyme
2003 StandoutNobel
Glyceryl‐S‐Acyl Carrier Protein as an Intermediate in the Biosynthesis of Tetronate Antibiotics
2007
Deep-sea natural products
2008
Bad Bugs, No Drugs: No ESKAPE! An Update from the Infectious Diseases Society of America
2008 Standout
The involvement of RNA in ribosome function
2002 StandoutNatureNobel
The Structures of Antibiotics Bound to the E Site Region of the 50 S Ribosomal Subunit of Haloarcula marismortui: 13-Deoxytedanolide and Girodazole
2007 StandoutNobel
UCSF Chimera—A visualization system for exploratory research and analysis
2004 Standout
Natural products to drugs: natural product-derived compounds in clinical trials
2008 Standout
Trends in the search for bioactive microbial metabolites
1992 StandoutNobel
U2504 Determines the Species Specificity of the A-Site Cleft Antibiotics:
2009 StandoutNobel
On the structural basis of peptide‐bond formation and antibiotic resistance from atomic structures of the large ribosomal subunit
2004 StandoutNobel
Atroposelective Synthesis of Axially Chiral Biaryl Compounds
2005 Standout
Daptomycin: From the Mountain to the Clinic, with Essential Help from Francis Tally, MD
2010
Cascade Reactions in Total Synthesis
2006 Standout
Ribosomal crystallography: a flexible nucleotide anchoring tRNA translocation, facilitates peptide‐bond formation, chirality discrimination and antibiotics synergism
2004 StandoutNobel
A crevice adjoining the ribosome tunnel: Hints for cotranslational folding
2005 StandoutNobel
Structures of Five Antibiotics Bound at the Peptidyl Transferase Center of the Large Ribosomal Subunit
2003 StandoutNobel
Isolation and Identification of Three New 5-Alkenyl-3,3(2H)-furanones from Two Streptomyces species using a Genomic Screening Approach
2006 StandoutNobel
The Roles of Ribosomal Proteins in the Structure Assembly, and Evolution of the Large Ribosomal Subunit
2004 StandoutNobel
Antibacterial drug discovery in the resistance era
2016 StandoutNature
The Biosynthetic Logic of Polyketide Diversity
2009 Standout
One-pot access to l-5,6-dihalotryptophans and l-alknyltryptophans using tryptophan synthase
2016
Comprehensive genetic selection revealed essential bases in the peptidyl-transferase center
2006 StandoutNobel
23S rRNA base pair 2057–2611 determines ketolide susceptibility and fitness cost of the macrolide resistance mutation 2058A→G
2005 StandoutNobel
Drug Discovery and Natural Products: End of an Era or an Endless Frontier?
2009 StandoutScience
Structures of Triacetyloleandomycin and Mycalamide A Bind to the Large Ribosomal Subunit of Haloarcula marismortui
2009 StandoutNobel
23S rRNA 2058A→G Alteration Mediates Ketolide Resistance in Combination with Deletion in L22
2006 StandoutNobel
Synthese von 3‐α‐Chlorvinylcephalosporinen
1991
Antibiotic resistance is ancient
2011 StandoutNature
The Structural Basis of Large Ribosomal Subunit Function
2003 StandoutNobel
Chemical parameters influencing fine-tuning in the binding of macrolide antibiotics to the ribosomal tunnel
2007 StandoutNobel
Engineering enzymes for noncanonical amino acid synthesis
2018 StandoutNobel
Inhibition of peptide bond formation by pleuromutilins: the structure of the 50S ribosomal subunit from Deinococcus radiodurans in complex with tiamulin
2004 StandoutNobel
Naturally Occurring Cyclohexane Epoxides: Sources, Biological Activities, and Synthesis
2004
Antibiotics acting on the translational machinery
2003 StandoutNobel
Sampling the Antibiotic Resistome
2006 StandoutScience
Use of Lawesson's Reagent in Organic Syntheses
2007 Standout
Microbial metabolites: 45 years of wandering, wondering and discovering
2011 StandoutNobel
The First One-Pot Synthesis of l -7-Iodotryptophan from 7-Iodoindole and Serine, and an Improved Synthesis of Other l -7-Halotryptophans
2014
Unlocking Reactivity of TrpB: A General Biocatalytic Platform for Synthesis of Tryptophan Analogues
2017 StandoutNobel
Diversifying Vancomycin via Chemoenzymatic Strategies
2005
Structure-Based Strategies for Drug Design and Discovery
1992 Science
Structural and Biochemical Studies of a Fluoroacetyl-CoA-Specific Thioesterase Reveal a Molecular Basis for Fluorine Selectivity
2010 StandoutNobel
Chemie, Biologie und medizinische Anwendungen der Glycopeptid-Antibiotika
1999
Diverse and abundant antibiotic resistance genes in Chinese swine farms
2013 Standout
STUDIES ON PENICILLINASE INHIBITORS PRODUCED BY MICROORGANISMS
1972 StandoutNobel
Ribosome-binding activities and antimicrobial activities of tylosin and its related compounds.
1983 StandoutNobel
Structural basis for cross-resistance to ribosomal PTC antibiotics
2008 StandoutNobel
Synthesis of β-Branched Tryptophan Analogues Using an Engineered Subunit of Tryptophan Synthase
2016 StandoutNobel
Functional Oligothiophenes: Molecular Design for Multidimensional Nanoarchitectures and Their Applications
2009 Standout
Properties and Synthetic Utility ofN-Substituted Benzotriazoles
1998 Standout
A Panel of TrpB Biocatalysts Derived from Tryptophan Synthase through the Transfer of Mutations that Mimic Allosteric Activation
2016 StandoutNobel
New iminophosphorane-mediated synthesis of thieno[3′,2′:4,5]thieno[3,2-d]pyrimidin-4(3H)-ones and 5H-2,3-dithia-5,7-diaza-cyclopenta[c,d]indenes
2008
In Vitro and In Vivo Activity of Penicillinase Inhibitor KA-107 Against Staphylococcus aureus FS-1277
1973 StandoutNobel
Screening and Isolation of Penicillinase Inhibitor, KA-107
1973 Nobel
ANTIBIOTICS TARGETING RIBOSOMES: Resistance, Selectivity, Synergism, and Cellular Regulation
2005 StandoutNobel
Origins and Evolution of Antibiotic Resistance
2010 Standout
Cu-Catalyzed Azide−Alkyne Cycloaddition
2008 StandoutNobel
Synthesis of New Polyfused Thienopyrimidine, Thienopyridine, Thienothiazine, Thienoxazine, and Thienodiazepine Derivatives
2003
Works of J. L. OTT being referenced
Synthesis and evaluation of tylosin-related macrolides modified at the aldehyde function: a new series of orally effective antibiotics
1988
Structure-activity studies of 20-deoxo-20-amino derivatives of tylosin-related macrolides.
1989
A80915, a new antibiotic complex produced by Streptomyces aculeolatus. Discovery, taxonomy, fermentation, isolation, characterization, and antibacterial evaluation.
1990
Oral absorption of cephalosproin antibiotics 2. Expanded structure-activity relationships of 7-arylacetamido-3-substituted cephalosporins
1988
Synthesis and antibacterial evaluation of N-alkyl vancomycins.
1989
Synthesis and antimicrobial evaluation of 20-deoxo-20(3,5-dimethylpiperidin-1-yl)desmycosin (tilmicosin, EL-870) and related cyclic amino derivatives.
1989
Synthesis and antibacterial activity of N-acyl vancomycins.
1988
Enzymatic and chemical modifications of lipopeptide antibiotic A21978C: The synthesis and evaluation of daptomycin (LY146032).
1988
Structure-activity studies among 16-membered macrolide antibiotics related to tylosin.
1982
Chemistry of cephalosporin antibiotics. 28. Preparation and biological activity of 3-(substituted)vinyl cephalosporins
1975
Orally absorbable cephalosporin antibiotics. 2. Structure-activity studies of bicyclic glycine derivatives of 7-aminodeacetoxycephalosporanic acid
1985
IN VITRO AND IN VIVO METHODOLOGY FOR DETECTING AND EVALUATING INHIBITORS OF TRANSFER OF RESISTANCE FACTORS
1971