Citation Impact
Citing Papers
( R )-2-Hydroxyglutarate Is Sufficient to Promote Leukemogenesis and Its Effects Are Reversible
2013 StandoutScienceNobel
TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms
1991
cDNA cloning and chromosomal localization of the human α‐adrenergic receptor kinase
1991 StandoutNobel
MicroRNAs
2004 Standout
Stem cells, cancer, and cancer stem cells
2001 StandoutNature
Establishment and characterization of a unique human cell line that proliferates dependently on GM‐CSF, IL‐3, or erythropoietin
1989
Increased Radiosensitivity and the Basic Defect in Ataxia Telangiectasia
1989
The level of CD8 expression can determine the outcome of thymic selection
1992 StandoutNobel
AID Is Required for c-myc/IgH Chromosome Translocations In Vivo
2004 StandoutNobel
The t(4;11) chromosome translocation of human acute leukemias fuses the ALL-1 gene, related to Drosophila trithorax, to the AF-4 gene
1992
Reshaping human antibodies for therapy
1988 StandoutNatureNobel
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Molecular Biology and Function of CD4 and CD8
1989
Fusion of the dominant negative transcription regulator CHOP with a novel gene FUS by translocation t(12;16) in malignant liposarcoma
1993
Caenorhabditis elegans CED-9 protein is a bifunctional cell-death inhibitor
1997 StandoutNatureNobel
Translational activation of the lck proto-oncogene
1988 StandoutNatureNobel
Control of c-myc Regulation in Normal and Neoplastic Cells
1991
C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2
1994 StandoutNobel
Activation of C. elegans cell death protein CED-9 by an ammo-acid substitution in a domain conserved in Bcl-2
1994 StandoutNatureNobel
Philadelphia chromosomal breakpoints are clustered within a limited region, bcr, on chromosome 22
1984 Standout
Degradation of nuclear oncoproteins by the ubiquitin system in vitro.
1991 StandoutNobel
Treatment of Cutaneous T-Cell Lymphoma by Extracorporeal Photochemotherapy
1987 Standout
Checkpoints: Controls That Ensure the Order of Cell Cycle Events
1989 StandoutScienceNobel
The human T-cell receptor α-chain gene maps to chromosome 14
1985 StandoutNatureNobel
Analysis of the 3' flanking region of the human c-myc gene in lymphomas with the t(8;22) and t(2;8) chromosomal translocations
1986
Activation of a translocated human c-myc gene by an enhancer in the immunoglobulin heavy-chain locus
1984 StandoutNatureNobel
Human Breast Cancer: Correlation of Relapse and Survival with Amplification of the HER-2/neuOncogene
1987 StandoutScience
Involvement of c-myc in MuLV-induced T cell lymphomas in mice: frequency and mechanisms of activation.
1984
An appraisal of the application of recombinant DNA techniques to chromosome defects
1985
Activation Of Cellular Oncogenes in Hemopoietic Cells by Chromosome Translocation
1986
Cutaneous T Cell Lymphoma
1986
A cluster of chromosome 11p13 translocations found via distinct D-D and D-D-J rearrangements of the human T cell receptor delta chain gene.
1988
The t(11;14)(p15;q11) in a T-Cell Acute Lymphoblastic Leukemia Cell Line Activates Multiple Transcripts, Including Ttg-1, a Gene Encoding a Potential Zinc Finger Protein
1989
Murine T lymphomas with retroviral inserts in the chromosomal 15 locus for plasmacytoma variant translocations
1985 Nature
Transcriptionally active c- myc oncogene is contained within NIARD, a DNA sequence associated with chromosome translocations in B-cell neoplasia
1983
The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein.
1989
THE MOLECULAR GENETICS OF CELLULAR ONCOGENES
1984
Granulocyte colony-stimulating factor gene transfer suppresses tumorigenicity of a murine adenocarcinoma in vivo.
1991
Amplification of N- myc in Untreated Human Neuroblastomas Correlates with Advanced Disease Stage
1984 StandoutScienceNobel
Isolation of the proto-oncogene c-myb from D. melanogaster
1985 StandoutNobel
Distinctive Chromosomal Abnormalities in Histologic Subtypes of Non-Hodgkin's Lymphoma
1982
Diagnostic and prognostic significance of Sezary cells in peripheral blood smears from patients with cutaneous T cell lymphoma
1985
Cell type-specific enhancer element associated with a mouse MHC gene, Eβ
1984 StandoutNatureNobel
Association of Multiple Copies of the N-mycOncogene with Rapid Progression of Neuroblastomas
1985 Standout
Nucleotide sequence of the human N-myc gene.
1986 StandoutNobel
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Amplification and Rearrangement of Hu- ets -1 in Leukemia and Lymphoma with Involvement of 11q23
1986 Science
Chromosome translocation can occur on either side of the c-myc oncogene in Burkitt lymphoma cells
1984 Nature
Papillomavirus sequences integrate near cellular oncogenes in some cervical carcinomas.
1987
Mammalian mediator of transcriptional regulation and its possible role as an end-point of signal transduction pathways
1998 StandoutNobel
Amplification of the c- myb Oncogene in a Case of Human Acute Myelogenous Leukemia
1984 Science
Polymorphisms of a human variable heavy chain gene show linkage with constant heavy chain genes.
1984 StandoutNobel
Expression of a translocated c-abl gene in hybrids of mouse fibroblasts and chronic myelogenous leukaemia cells
1986 Nature
Variant (6;15) translocations in murine plasmacytomas involve a chromosome 15 locus at least 72 kb from the c-myc oncogene.
1985
Aberrant c-myc RNAs of Burkitt's lymphoma cells have longer half-lives.
1985
Human c-myc onc gene is located on the region of chromosome 8 that is translocated in Burkitt lymphoma cells.
1982
LAG-3, a novel lymphocyte activation gene closely related to CD4.
1990
A cellular oncogene (c-Ki-ras) is amplified, overexpressed, and located within karyotypic abnormalities in mouse adrenocortical tumour cells
1983 StandoutNatureNobel
Amplified C lambda and c-abl genes are on the same marker chromosome in K562 leukemia cells.
1983
Analysis of the structure, transcripts, and protein products of bcl-2, the gene involved in human follicular lymphoma.
1986
Identification of nuclear proteins encoded by viral and cellular myc oncogenes
1983 StandoutNatureNobel
Photochemotherapy for cutaneous T cell lymphoma
1984
Chromosome 8 breakpoint far 3′ of the c-myc oncogene in a Burkitt's lymphoma 2;8 variant translocation is equivalent to the murine pvt-1 locus.
1986
Variant (6 ; 15) translocation in a murine plasmacytoma occurs near an immunoglobulin κ gene but far from the myc oncogene
1984 Nature
Evolution of tumours and the impact of molecular oncology
1985 Nature
Deregulation of c-myc gene expression in human colon carcinoma is not accompanied by amplification or rearrangement of the gene.
1985
Germ-Line Transmission of a c- abl Mutation Produced by Targeted Gene Disruption in ES Cells
1989 Science
Proviral Integration Site Mis-1 in Rat Thymomas Corresponds to the pvt-1 Translocation Breakpoint in Murine Plasmacytomas
1986
Chromatin structure around the c-myc gene in Burkitt lymphomas with upstream and downstream translocation points.
1985
Enzymatic Amplification of β-Globin Genomic Sequences and Restriction Site Analysis for Diagnosis of Sickle Cell Anemia
1985 StandoutScienceNobel
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
Localization of a lymphocyte-specific protein tyrosine kinase gene (lck) at a site of frequent chromosomal abnormalities in human lymphomas.
1986
The mechanism of chromosomal translocation t(11;14) involving the T-cell receptor C delta locus on human chromosome 14q11 and a transcribed region of chromosome 11p15.
1988
Enhanced expression of the human gene N-myc consequent to amplification of DNA may contribute to malignant progression of neuroblastoma.
1984 StandoutNobel
Identification of a human transcription unit affected by the variant chromosomal translocations 2;8 and 8;22 of Burkitt lymphoma.
1989 StandoutNobel
T-Cell Receptor Gene Rearrangements as Clinical Markers of Human T-Cell Lymphomas
1985
A lymphocyte-specific protein-tyrosine kinase gene is rearranged and overexpressed in the murine T cell lymphoma LSTRA
1985 StandoutNobel
Lambda lg constant region genes are translocated to chromosome 8 in Burkitt's lymphoma with t(8:22
1983
The future of immune checkpoint therapy
2015 StandoutScienceNobel
Normal Development of Mice Deficient in β 2 M, MCClass I Proteins, and CD8 + T Cells
1990 StandoutScienceNobel
The gene encoding the T-cell surface protein T4 is located on human chromosome 12.
1986 StandoutNobel
Viruses in Human Cancers
1991 StandoutScienceNobel
Sequence of a human immunoglobulin gamma 3 heavy chain constant region gene: comparison with the other human Cγgenes
1986
Fusion of DNA region to murine immunoglobulin heavy chain locus corresponds to plasmacytoma-associated chromosome translocation.
1983
Homogeneously staining chromosomal regions contain amplified copies of an abundantly expressed cellular oncogene (c-myc) in malignant neuroendocrine cells from a human colon carcinoma.
1983 StandoutNobel
Activation of MYC in a masked t(8;17) translocation results in an aggressive B-cell leukemia.
1989
Truncation of exon 1 from the c-myc gene results in prolonged c-myc mRNa stability.
1985
The Molecular Genetics of Cancer
1987 StandoutScienceNobel
B Lineage—Specific Interactions of an Immunoglobulin Enhancer with Cellular Factors in Vivo
1985 StandoutScienceNobel
Translocation joins c-myc and immunoglobulin γ1 genes in a Burkitt lymphoma revealing a third exon in the c-myc oncogene
1983 Nature
The bcl-2 candidate proto-oncogene product is a 24-kilodalton integral-membrane protein highly expressed in lymphoid cell lines and lymphomas carrying the t(14;18) translocation.
1989
Chromosome studies in adult T-cell leukemia in Japan: significance of trisomy 7
1981
Differential expression of the normal and of the translocated human c-myc oncogenes in B cells.
1983
A cellular gene encodes scrapie PrP 27-30 protein
1985 StandoutNobel
Cellular myc oncogene is altered by chromosome translocation to an immunoglobulin locus in murine plasmacytomas and is rearranged similarly in human Burkitt lymphomas.
1983
Amplification and expression of a cellular oncogene (c-myc) in human gastric adenocarcinoma cells.
1985
Chromosome Aberrations and Cancer
1991 Science
Current status of cytogenetic research in childhood acute lymphoblastic leukemia
1993
Translocation and Rearrangements of the c- myc Oncogene Locus in Human Undifferentiated B-Cell Lymphomas
1983 Science
Basal and human papillomavirus E6 oncoprotein-induced degradation of Myc proteins by the ubiquitin pathway
1998 StandoutNobel
Oncogene Amplification in Tumor Cells
1986
A 14;18 and an 8;14 chromosome translocation in a cell line derived from an acute B-cell leukemia.
1984
Cell-type-specific contacts to immunoglobulin enhancers in nuclei
1985 StandoutNatureNobel
Synthesis of Kappa Light Chains by Cell Lines Containing an 8;22 Chromosomal Translocation Derived from a Male Homosexual with Burkitt's Lymphoma
1983 Science
Cytogenetic studies on patients with chronic T cell leukemia/lymphoma
1984
Clinical and biologic features of childhood T-cell leukemia with the t(11;14)
1991
Transcriptional activation of the translocated c- myc oncogene in Burkitt lymphoma
1983
Expression of N-myc in teratocarcinoma stem cells and mouse embryos
1985 StandoutNatureNobel
Generation of a Variant T(2;8) Translocation of Burkitt's Lymphoma by Site-Specific Recombination via the Kappa Light-Chain Joining Signals
1987
A human chromosome 8 region with abnormalities in B cell, HTLV-I+ T cell and c-myc amplified tumours.
1987
Molecular Cloning of the Chromosomal Breakpoint of B-Cell Lymphomas and Leukemias with the t(11;14) Chromosome Translocation
1984 Science
Human c-fos oncogene mapped within chromosomal region 14q21----q31.
1984
Amplification of the c-myc oncogene in one of five human breast carcinoma cell lines.
1984
Human N-myc gene contributes to neoplastic transformation of mammalian cells in culture
1985 StandoutNatureNobel
Works of J Finan being referenced
The human V pre B gene is located on chromosome 22 near a cluster of $${\text{V}}_{\lambda _1 } $$ gene segments
1988
Molecular analysis of a t(7;14)(g35;g32) chromosome translocation in a T cell leukemia of a patient with ataxia telangiectasia
1988
Growth factor requirements of childhood acute leukemia: establishment of GM-CSF-dependent cell lines
1987
Clonal Characteristics of Cutaneous T Cell Lymphomas: Cytogenetic Evidence from Blood, Lymph Nodes, and Skin
1982
Association of amplified oncogene c-myc with an abnormally banded chromosome 8 in a human leukaemia cell line
1983 Nature
Molecular cloning and characterization of a cDNA for human granulocyte colony-stimulating factor (G-CSF) from a glioblastoma multiforme cell line and localization of the G-CSF gene to chromosome band 17q21.
1987
The chromosome 14 breakpoint in neoplastic B cells with the t(11;14) translocation involves the immunoglobulin heavy chain locus.
1984
Locus of the α-Chain of the T-Cell Receptor Is Split by Chromosome Translocation in T-Cell Leukemias
1985 Science
Clustering of breakpoints on chromosome 10 in acute T-cell leukemias with the t(10;14) chromosome translocation.
1989
Deregulation of c- myc by Translocation of the α-Locus of the T-Cell Receptor in T-Cell Leukemias
1986 Science
The gene encoding the T4 antigen maps to human chromosome 12.
1986
Isochromosome 17 in Atypical Myeloproliferative and Lymphoproliferative Disorders2
1977
Karyotypic differences between primary cultures and cell lines from tumors with the human T-cell leukemia virus.
1984
Sequence analysis of the MYC oncogene involved in the t(8;14)(q24;q11) chromosome translocation in a human leukemia T-cell line indicates that putative regulatory regions are not altered.
1988
Translocation of an immunoglobulin kappa locus to a region 3' of an unrearranged c-myc oncogene enhances c-myc transcription.
1983
Alpha-chain locus of the T-cell antigen receptor is involved in the t(10;14) chromosome translocation of T-cell acute lymphocytic leukemia.
1987
Heterogeneity of chromosome 22 breakpoint in Philadelphia-positive (Ph+) acute lymphocytic leukemia.
1986
Translocation of immunoglobulin VH genes in Burkitt lymphoma.
1982
The nerve growth factor receptor gene is at human chromosome region 17q12-17q22, distal to the chromosome 17 breakpoint in acute leukemias.
1986
Preleukemia and leukemia with 12p− and 19q+ chromosome alterations following alkeran therapy
1985
Cytogenetics of chronic T cell leukemia, including two patients with a 14q+ translocation
1978
A human c-erbA oncogene homologue is closely proximal to the chromosome 17 breakpoint in acute promyelocytic leukemia.
1984
Molecular analysis of a t(14;14) translocation in leukemic T-cells of an ataxia telangiectasia patient.
1989
Transcriptional activation of an unrearranged and untranslocated c-myc oncogene by translocation of a C lambda locus in Burkitt.
1983
Proliferation, differentiation, and cytogenetics of chronic leukemic B lymphocytes cultured with mitomycin-treated normal cells
1981
Suppression of the normal mouse c-myc oncogene in human lymphoma cells
1985 Nature