Citation Impact
Citing Papers
Targeting of Diacylglycerol Degradation to M1 Muscarinic Receptors by ß-Arrestins
2007 StandoutScienceNobel
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
1992 StandoutNatureNobel
Use of cytochalasin B to distinguish between early and late events in neutrophil activation
1980
G Protein-coupled Receptor Kinase and β-Arrestin-mediated Desensitization of the Angiotensin II Type 1A Receptor Elucidated by Diacylglycerol Dynamics
2006 StandoutNobel
Immunochemical identification of protein kinase C isozymes as products of discrete genes
1987
Functions of Sphingolipids and Sphingolipid Breakdown Products in Cellular Regulation
1989 Science
Protein kinase C and T cell activation
1990
The molecular heterogeneity of protein kinase C and its implications for cellular regulation
1988 StandoutNature
Metabolic effects of short‐chain ceramide and glucosylceramide on sphingolipids and protein kinase C
1992
The generation of diversity and pattern in animal development
1992 StandoutNobel
Interleukin-1 stimulates diacylglycerol production in T lymphocytes by a novel mechanism
1988
Overproduction of protein kinase C causesdisordered growth control in rat fibroblasts
1988
Molecular Events Mediating T Cell Activation
1990
Disappearance of diacylglycerol kinase translocation in ras-transformed cells
1988
Activation of Human Neutrophil NADPH Oxidase by Phosphatidic Acid or Diacylglycerol in a Cell-free System
1999
A fourth type of rabbit protein kinase C
1988
Crystal structure of the β2 adrenergic receptor–Gs protein complex
2011 StandoutNatureNobel
α-Synuclein Cooperates with CSPα in Preventing Neurodegeneration
2005 StandoutNobel
The drosophila gastrulation gene concertina encodes a Gα-like protein
1991 StandoutNobel
[10] Assays for G-protein regulation of phospholipase C activity
1994
Enhanced Phagocytosis through Inhibition of de Novo Ceramide Synthesis
2003 StandoutNobel
FMRFamide reverses protein phosphorylation produced by 5-HT and cAMP in Aplysia sensory neurons
1989 StandoutNatureNobel
Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold
1995 StandoutNobel
Effect of harvesting methods, growth conditions and growth phase on diacylglycerol levels in cultured human adherent cells
1988
Injection of the cAMP-responsive element into the nucleus of Aplysia sensory neurons blocks long-term facilitation
1990 StandoutNatureNobel
Cell-permeable Ceramides Prevent the Activation of Phospholipase D by ADP-ribosylation Factor and RhoA
1997
Emptying of intracellular Ca2+ stores releases a novel small messenger that stimulates Ca2+ influx
1993 StandoutNatureNobel
Alkyl-linked diglycerides inhibit protein kinase C activation by diacylglycerols
1988
Altered growth regulation and enhanced tumorigenicity of NIH 3T3 fibroblasts transfected with protein kinase C-I cDNA
1988
The rat brain synucleins; family of proteins transiently associated with neuronal membrane
1991
Source and role of diacylglycerol formed during phagocytosis of opsonized yeast particles and associated respiratory burst in human neutrophils
1991
The heterogeneity of protein kinase C in various rat tissues
1988
Hippocampal protein kinase C activity is reduced in poor spatial learners
1990
Local and Systemic Effects of Intradermal Recombinant Interferon-γ in Patients with Lepromatous Leprosy
1986 StandoutNobel
Synergistic effect of A23187 and a phorbol ester on amylase secretion from rabbit pancreatic acini
1984
Protein kinase C regulates ionic conductance in hippocampal pyramidal neurons: electrophysiological effects of phorbol esters.
1985
Regulation of sn-1,2-diacylglycerol second-messenger formation in thrombin-stimulated human platelets. Potentiation by protein kinase C inhibitors
1990
Rapid internalization of the transferrin receptor in K562 cells is triggered by ligand binding or treatment with a phorbol ester.
1984
Molecular species analysis of a product of phospholipase D activation. Phosphatidylethanol is formed from phosphatidylcholine in phorbol ester- and bradykinin-stimulated PC12 cells.
1992
Ca2+-dependent and -independent release of neurotransmitters from PC12 cells: a role for protein kinase C activation?
1984
Phorbol ester- and diacylglycerol-mediated desensitization of cardiac beta-adrenergic receptors.
1985
Activation of a Plasma Membrane–Associated Neutral Sphingomyelinase and Concomitant Ceramide Accumulation During IgG-Dependent Phagocytosis in Human Polymorphonuclear Leukocytes
1998 StandoutNobel
Protein kinase C phosphorylates pp60src at a novel site
1985
Choline-linked Phosphoglycerides
1989
Phospholipase D catalyzes phospholipid metabolism in chemotactic peptide-stimulated HL-60 granulocytes.
1988
Heterogeneous localization of protein kinase C in rat brain: autoradiographic analysis of phorbol ester receptor binding
1986
The long and the short of long–term memory—a molecular framework
1986 StandoutNatureNobel
Phorbol ester induces desensitization of adenylate cyclase and phosphorylation of the beta-adrenergic receptor in turkey erythrocytes.
1984
Modulation of renal epithelial cell growth by glucosylceramide. Association with protein kinase C, sphingosine, and diacylglycerol.
1991
Phosphorylation of receptors for insulin and insulin-like growth factor I. Effects of hormones and phorbol esters.
1986
Sphingosine inhibits phosphatidate phosphohydrolase in human neutrophils by a protein kinase C-independent mechanism
1991
Modulation of the free sphingosine levels in human neutrophils by phorbol esters and other factors.
1988
Isozymic forms of rat brain Ca2+-activated and phospholipid-dependent protein kinase.
1986
Decreased tyrosine kinase activity of insulin receptor isolated from rat adipocytes rendered insulin-resistant by catecholamine treatment in vitro
1986
Immunochemical evidence that three protein kinase C isozymes increase in abundance during HL-60 differentiation induced by dimethyl sulfoxide and retinoic acid.
1988
Role of T3 surface molecules in human T-cell activation: T3-dependent activation results in an increase in cytoplasmic free calcium.
1984
Ceramide regulates oxidant release in adherent human neutrophils
1994
Differences in the sites of phosphorylation of the insulin receptor in vivo and in vitro.
1985
Characterization of the sites phosphorylated on tyrosine hydroxylase by Ca2+ and phospholipid‐dependent protein kinase, calmodulin‐dependent multiprotein kinase and cyclic AMP‐dependent protein kinase
1985
Phospholipase D activation in a cell-free system from human neutrophils by phorbol 12-myristate 13-acetate and guanosine 5'-O-(3-thiotriphosphate). Activation is calcium dependent and requires protein factors in both the plasma membrane and cytosol.
1991
Phorbol esters and beta-adrenergic agonists mediate desensitization of adenylate cyclase in rat glioma C6 cells by distinct mechanisms.
1985
The Role of Protein Kinase C in Transmembrane Signalling
1986
Phorbol esters modulate insulin receptor phosphorylation and insulin action in cultured hepatoma cells.
1984
Amiloride inhibits phorbol ester-stimulated Na+/H+ exchange and protein kinase C. An amiloride analog selectively inhibits Na+/H+ exchange.
1985
Activation of protein kinase C by Triton X-100 mixed micelles containing diacylglycerol and phosphatidylserine.
1985
Interferon-alpha selectively activates the beta isoform of protein kinase C through phosphatidylcholine hydrolysis.
1990
Bombesin stimulates distinct time-dependent changes in the sn-1,2-diradylglycerol molecular species profile from Swiss 3T3 fibroblasts as analysed by 3,5-dinitrobenzoyl derivatization and h.p.l.c. separation
1993
Effect of phorbol 12-myristate 13-acetate and its analogue 4 alpha-phorbol 12,13-didecanoate on protein phosphorylation and lysosomal enzyme release in rabbit neutrophils.
1984
Diacylglycerol stimulates DNA synthesis and cell division in mouse 3T3 cells: role of Ca2+-sensitive phospholipid-dependent protein kinase.
1984
Activation of the human neutrophil nicotinamide adenine dinucleotide phosphate (NADPH)-oxidase by protein kinase C.
1985
A novel phorbol ester receptor/protein kinase, nPKC, distantly related to the protein kinase C family
1988
Platelet-derived growth factor mimics phorbol diester action on epidermal growth factor receptor phosphorylation at threonine-654.
1985
Kinetic analysis of 1,2-diacylglycerol mass levels in cultured fibroblasts. Comparison of stimulation by alpha-thrombin and epidermal growth factor.
1988
The Role of the T3/Antigen Receptor Complex in T-Cell Activation
1986
Sphingosine inhibition of protein kinase C activity and of phorbol dibutyrate binding in vitro and in human platelets.
1986
Involvement of GTP-binding proteins in actin polymerization in human neutrophils.
1990
Down-regulation of protein kinase C is due to an increased rate of degradation
1987
Regulation of transmembrane signaling by receptor phosphorylation
1987 StandoutNobel
Phospholipase D-mediated diradylglycerol formation coincides with H2O2 and lactoferrin release in adherent human neutrophils.
1994
Prooxidant States and Tumor Promotion
1985 StandoutScience
Diacylglycerol metabolism in mast cells. Analysis of lipid metabolic pathways using molecular species analysis of intermediates.
1987
Cell Signalling Through Phospholipid Metabolism
1986
A specific inhibitor of phosphatidylinositol 3-kinase, 2-(4-morpholinyl)-8-phenyl-4H-1-benzopyran-4-one (LY294002).
1994 Standout
Ectopic Expression of the Serotonin 1c Receptor and the Triggering of Malignant Transformation
1989 StandoutScienceNobel
sn-1,2-Dioctanoylglycerol. A cell-permeable diacylglycerol that mimics phorbol diester action on the epidermal growth factor receptor and mitogenesis.
1985
Protein kinase C: Rapid enzyme purification and substrate-dependence of the diacylglycerol effect
1984
Multiple doses of diacylglycerol and calcium ionophore are necessary to activate AP-1 enhancer activity and induce markers of macrophage differentiation.
1990
Stimulus-response coupling in insulin-secreting HIT cells. Effects of secretagogues on cytosolic Ca2+, diacylglycerol, and protein kinase C activity.
1990
Intracellular Signaling by Hydrolysis of Phospholipids and Activation of Protein Kinase C
1992 StandoutScience
Tumor-promoting phorbol diesters mediate phosphorylation of the epidermal growth factor receptor.
1984
Purification to homogeneity of protein kinase C from bovine brain-identity with the phorbol ester receptor.
1984
Exogenous sn-1,2-diacylglycerols containing saturated fatty acids function as bioregulators of protein kinase C in human platelets.
1985
Phosphatidylcholine Hydrolysis by Phospholipase D Determines Phosphatidate and Diglyceride Levels in Chemotactic Peptide-stimulated Human Neutrophils
1989
Clonal Deletion Versus Clonal Anergy: The Role of the Thymus in Inducing Self Tolerance
1990 StandoutScienceNobel
The dependence on Ca2+ of phosphatidylinositol breakdown and enzyme secretion in rabbit neutrophils stimulated by formylmethionyl-leucylphenylalanine or ionomycin
1981
β-Adrenergic Receptor Kinase: Primary Structure Delineates a Multigene Family
1989 StandoutScienceNobel
Isolation of the oncogene and epidermal growth factor-induced transin gene: complex control in rat fibroblasts.
1986
Desensitization of the turkey erythrocyte beta-adrenergic receptor in a cell-free system. Evidence that multiple protein kinases can phosphorylate and desensitize the receptor.
1985
Activation of protein kinase C by oleic acid. Determination and analysis of inhibition by detergent micelles and physiologic membranes: requirement for free oleate.
1992
Postnatal development of a brain-specific subspecies of protein kinase C in rat
1988
Molecular Cloning and Characterization of a Novel Human Diacylglycerol Kinase ζ
1996
Control of Ca2+ entry into HL60 and U937 human leukaemia cells by the filling state of the intracellular Ca2+ stores
1993
Protein kinase C phosphorylation of the EGF receptor at a threonine residue close to the cytoplasmic face of the plasma membrane
1984 Nature
Transmembrane signaling pathways involved in phagocytosis and associated activation of NADPH oxidase mediated by FcγRs in human neutrophils
1993
Molecular and Cellular Mechanisms of Leukocyte Chemotaxis
1981 Science
Tumor-promoting phorbol esters increase the Km of the ATP-binding site of the insulin receptor kinase from rat adipocytes.
1986
Cell type-specific expression of protein kinase C isozymes in the rabbit cerebellum.
1988
Regulation of Phospholipase D in HL-60 Granulocytes
1989
Molecular species analysis of mitogen-stimulated 1,2-diglycerides in fibroblasts. Comparison of alpha-thrombin, epidermal growth factor, and platelet-derived growth factor.
1990
Activation, desensitization, and recycling of frog erythrocyte beta-adrenergic receptors. Differential perturbation by in situ trypsinization.
1984 StandoutNobel
Isolation of a calcium-dependent 35-kilodalton substrate for the epidermal growth factor receptor/kinase from A-431 cells.
1984 StandoutNobel
Pancreatic amylase secretion and cytoplasmic free calcium. Effects of ionomycin, phorbol dibutyrate and diacylglycerols alone and in combination
1985
The role of protein kinase C in cell surface signal transduction and tumour promotion
1984 StandoutNature
Transmembrane signaling by interferon alpha involves diacylglycerol production and activation of the epsilon isoform of protein kinase C in Daudi cells.
1991
Photoaffinity labeling of the beta-adrenergic receptor.
1981 StandoutNobel
Sphingomyelin turnover induced by vitamin D3 in HL-60 cells
1989
Insulin- and phorbol ester-stimulated phosphorylation of ribosomal protein S6.
1985
The regulation and cellular functions of phosphatidylcholine hydrolysis
1990
Activation of a Plasma Membrane–Associated Neutral Sphingomyelinase and Concomitant Ceramide Accumulation During IgG-Dependent Phagocytosis in Human Polymorphonuclear Leukocytes
1998 StandoutNobel
Pleiotropic loss of activation pathways in a T-cell receptor α-chain deletion variant of a cytolytic T-cell clone
1987 StandoutNatureNobel
Phorbol myristate acetate stimulates ATP-dependent calcium transport by the plasma membrane of neutrophils.
1984
Bipartite Ca 2+ -Binding Motif in C 2 Domains of Synaptotagmin and Protein Kinase C
1996 StandoutScienceNobel
Sphingosine Blocks Human Polymorphonuclear Leukocyte Phagocytosis Through Inhibition of Mitogen-Activated Protein Kinase Activation
1999 StandoutNobel
Vasopressin induces V1 receptors to activate phosphatidylinositol- and phosphatidylcholine-specific phospholipase C and stimulates the release of arachidonic acid by at least two pathways in the smooth muscle cell line, A-10.
1988
Phorbol ester causes desensitization of gonadotropin-responsive adenylate cyclase in a murine Leydig tumor cell line.
1985
Isolation of cDNA clones encoding protein kinase C: evidence for a protein kinase C-related gene family.
1987
Quantitative Changes in Polyphosphoinositides 1,2-Diacylglycerol and Inositol 1,4,5-Trisphosphate by Platelet-derived Growth Factor and Prostaglandin F2α
1989
An early decrease in phosphatidylinositol turnover occurs on induction of friend cell differentiation and precedes the decrease in c-myc expression
1985
1,2-Didecanoylglycerol and Phorbol 12,13-Dibutyrate Enhance Anterior Pituitary Hormone Secretionin Vitro
1985
Regulation of the epidermal growth factor receptor by phosphorylation
1985
Phosphorylation of a chromaffin granule-binding protein by protein kinase C.
1985
Ca2+-dependent and phorbol ester activating phosphorylation of a 36K-dalton protein of rat basophilic leukemia cell membranes and immunoprecipitation of the phosphorylated protein with IgE-anti IgE system
1984
Stimulation of Phosphatidylcholine Hydrolysis, Diacylglycerol Release, and Arachidonic Acid Production by Oncogenic Ras Is a Consequence of Protein Kinase C Activation
1989
Identification of sphingomyelin turnover as an effector mechanism for the action of tumor necrosis factor alpha and gamma-interferon. Specific role in cell differentiation.
1991
Mass measurement of inositol 1,4,5-trisphosphate and sn-1,2-diacylglycerol in bombesin-stimulated Swiss 3T3 mouse fibroblasts
1990
Intracellular Ca2+ and phorbol esters synergistically inhibit internalization of epidermal growth factor in pancreatic acini
1984
Pure β-adrenergic receptor: the single polypeptide confers catecholamine responsiveness to adenylate cyclase
1983 StandoutNatureNobel
Targeting the Receptor-G q Interface to Inhibit in Vivo Pressure Overload Myocardial Hypertrophy
1998 StandoutScienceNobel
Dual actions of phorbol esters on cytosolic free Ca2+ concentrations and reconstitution with ionomycin of acute thyrotropin-releasing hormone responses.
1985
Isolation and characterization of PKC-L, a new member of the protein kinase C-related gene family specifically expressed in lung, skin, and heart.
1991
Role of ceramide as a lipid mediator of 1 alpha,25-dihydroxyvitamin D3-induced HL-60 cell differentiation.
1990
Activation of Protein Kinase C by Naturally Occurring Ether-linked Diglycerides
1989
The phorbol ester, TPA inhibits glucagon‐stimulated adenylate cyclase activity
1984
Altered signal transduction in erbB-transformed cells. Implication of enhanced inositol phospholipid metabolism in erbB-induced transformation.
1987
Association of sequestered beta-adrenergic receptors with the plasma membrane: A novel mechanism for receptor down regulation
1984 StandoutNobel
Ceramide inhibition of phospholipase D and its relationship to RhoA and ARF1 translocation in GTPγS-stimulated polymorphonuclear leukocytes
2003 StandoutNobel
Intracellular Ca2+ and protein kinase C interact to regulate alpha 1-adrenergic- and bradykinin receptor-stimulated phospholipase A2 activation in Madin-Darby canine kidney cells
1991
Bidirectional control of cytosolic free calcium by thyrotropin-releasing hormone in pituitary cells
1985 Nature
Functional alteration of the beta-adrenergic receptor during desensitization of mammalian adenylate cyclase by beta-agonists.
1984
Is Cytosolic Ionized Calcium Regulating Neutrophil Activation?
1983 StandoutScienceNobel
Interactions between cyclic AMP‐ and phorbol ester‐dependent phosphorylation systems in S49 mouse lymphoma cells
1985
Protein kinase C activity appears to be required for the synthesis of platelet-activating factor and leukotriene B4 by human neutrophils.
1987
Studies and Perspectives of Protein Kinase C
1986 StandoutScience
Differential distribution of protein kinase C isozymes in the various regions of brain.
1987
Phorbol esters inhibit the fMet-Leu-Phe- and leukotriene B4-stimulated calcium mobilization and enzyme secretion in rabbit neutrophils.
1985
A Potential Second Messenger Role for Unsaturated Fatty Acids: Activation of Ca 2+ -Dependent Protein Kinase
1984 Science
Ceramide Inhibits IgG-Dependent Phagocytosis in Human Polymorphonuclear Leukocytes
1997 StandoutNobel
Cloning and expression of multiple protein kinase C cDNAs
1986
Evidence for the role of phosphorylase kinase, protein kinase C, and other Ca2+-sensitive protein kinases in the response of hepatocytes to angiotensin II and vasopressin.
1984
A model for intracellular translocation of protein kinase C involving synergism between Ca2+ and phorbol esters
1985 Nature
Characterization of protein kinase C and its role in catecholamine secretion from bovine adrenal-medullary cells
1985
Neuronal inhibition by the peptide FMRFamide involves opening of S K+ channels
1987 StandoutNatureNobel
Chemotactic peptide stimulated endogenous arachidonic acid metabolism in HL60 granulocytes
1981
Synaptotagmin: a Calcium Sensor on the Synaptic Vesicle Surface
1992 StandoutScienceNobel
Receptor class desensitization of leukocyte chemoattractant receptors.
1991
Sequences and Factors: A Guide to MHC Class-II Transcription
1992
Cardiac Function in Mice Overexpressing the β-Adrenergic Receptor Kinase or a βARK Inhibitor
1995 StandoutScienceNobel
Effects of a phorbol ester and diacyglycerols on secretion of mucin and arginine esterase by rat submandibular gland cells
1986
Phorbol ester effects on neurotransmission: interaction with neurotransmitters and calcium in smooth muscle.
1985
Maintenance of in Vivo Tolerance by Persistence of Antigen
1992 StandoutScienceNobel
The Complete Primary Structure of Protein Kinase C—the Major Phorbol Ester Receptor
1986 Science
Protein kinase C as a possible receptor protein of tumor-promoting phorbol esters.
1983
Phorbol esters stimulate the phosphorylation of receptors for insulin and somatomedin C.
1983
Protein kinase C activation induces conductance changes in Hermissenda photoreceptors like those seen in associative learning
1986 Nature
Multiphasic generation of diacylglycerol in thrombin-activated human platelets
1992
Modification of glycogen synthase activity in isolated rat hepatocytes by tumor-promoting phorbol esters: evidence for differential regulation of glycogen synthase and phosphorylase.
1983
Interleukin-1-mediated PGE2 production and sphingomyelin metabolism. Evidence for the regulation of cyclooxygenase gene expression by sphingosine and ceramide.
1992
12-0-Tetradecanoyl Phorbol-13-Acetate Stimulates Rat Growth Hormone (GH) Release through Different Pathways from that of Human Pancreatic GH-Releasing Factor*
1985
A genetic pathway for the specification of the vulval cell lineages of Caenorhabditis elegans
1987 StandoutNatureNobel
Inhibition of hCG‐stimulated adenylate cyclase in purified mouse Leydig cells by the phorbol ester PMA
1985
Generation of Calcium Oscillations in Fibroblasts by Positive Feedback Between Calcium and IP 3
1991 StandoutScienceNobel
Protein kinase C phosphorylates the synthetic peptide Arg-Arg-Lys-Ala-Ser-Gly-Pro-Pro-Val in the presence of phospholipid plus either Ca2+ or a phorbol ester tumor promoter
1984
Specificity and mechanism of protein kinase C activation by sn-1,2-diacylglycerols.
1986
Phorbol esters potentiate tyrosine phosphorylation of epidermal growth factor receptors in A431 membranes by a calcium-independent mechanism.
1984
A cDNA encoding protein kinase C identifies two species of mRNA in brain and GH3 cells.
1986
Complement receptor-mediated phagocytosis is associated with accumulation of phosphatidylcholine-derived diglyceride in human neutrophils. Involvement of phospholipase D and direct evidence for a positive feedback signal of protein kinase.
1992
Synergistic activation of type III protein kinase C by cis-fatty acid and diacylglycerol
1992
Metabolic rate of membrane-permeant diacylglycerol and its relation to human resting T-lymphocyte activation.
1991
Myocardial expression of a constitutively active alpha 1B-adrenergic receptor in transgenic mice induces cardiac hypertrophy.
1994 StandoutNobel
Protein kinase C catalyzes phosphorylation of guanylate cyclase in vitro.
1985
Antagonism of Catecholamine Receptor Signaling by Expression of Cytoplasmic Domains of the Receptors
1993 StandoutScienceNobel
Mechanism of phorbol diester-induced regulation of surface transferrin receptor involves the action of activated protein kinase C and an intact cytoskeleton.
1985
Involvement of Protein Kinase C in Platelet-activating Factor-stimulated Diacylglycerol Accumulation in Murine Peritoneal Macrophages
1989
Phorbol ester and diacylglycerol induce protein phosphorylation at tyrosine
1983 Nature
C-kinase phosphorylates the epidermal growth factor receptor and reduces its epidermal growth factor-stimulated tyrosine protein kinase activity.
1984
Possible involvement of protein kinase C and calcium ion in growth factor-induced expression of c-myc oncogene in Swiss 3T3 fibroblasts.
1986
Molecular mechanisms of receptor desensitization using the β-adrenergic receptor-coupled adenylate cyclase system as a model
1985 StandoutNatureNobel
Tumor Necrosis Factor-α Activates the Sphingomyelin Signal Transduction Pathway in a Cell-Free System
1992 Science
An activator of protein kinase C (phorbol‐12‐myristate‐13‐acetate) augments 2‐chloroadenosine‐elicited accumulation of cyclic AMP in guinea pig cerebral cortical particulate preparations
1985
Characterization of protein kinase C in early Xenopus embryogenesis
1990
Dimerization: An Emerging Concept for G Protein–Coupled Receptor Ontogeny and Function
2002
Phosphorylation of hepatic 3-hydroxy-3-methylglutaryl coenzyme A reductase and modulation of its enzymic activity by calcium-activated and phospholipid-dependent protein kinase.
1985
Epidermal growth factor and potent phorbol tumor promoters induce epidermal growth factor receptor phosphorylation in a similar but distinctively different manner in human epidermoid carcinoma A431 cells.
1984
Phosphorylation of the glucose transporter in vitro and in vivo by protein kinase C
1985 Nature
On the Biological Occurrence and Regulation of 1-Acyl and 1-O-Alkyl-diradylglycerols in Human Neutrophils
1989
Phorbol esters induce differentiation in a pre-B-lymphocyte cell line by enhancing Na+/H+ exchange.
1984
A phorbol ester and A23187 act synergistically to release acetylcholine from the guinea pig ileum
1984
Turnover of Inositol Phospholipids and Signal Transduction
1984 Science
Regulation of the Ets-Related Transcription Factor Elf-1 by Binding to the Retinoblastoma Protein
1993 StandoutScienceNobel
Inhibition of receptor-mediated release of arachidonic acid by pertussis toxin
1984 StandoutNobel
Phosphorylation of bovine cardiac C-protein by protein kinase C
1985
A Region of Adenylyl Cyclase 2 Critical for Regulation by G Protein βγ Subunits
1995 StandoutScienceNobel
The Nature and Regulation of the Insulin Receptor: Structure and Function
1985
Purified rat brain calcium- and phospholipid-dependent protein kinase phosphorylates ribosomal protein S6.
1983
Dissociation of protein kinase C activation from phorbol ester-induced maturation of HL-60 leukemia cells.
1985
Phospholipid Turnover in Hormone Action
1984
Characterization of a ceramide-activated protein kinase: stimulation by tumor necrosis factor alpha.
1991
Response : Nitric Oxide and Arginine-Evoked Insulin Secretion
1992 StandoutScienceNobel
Phosphorylation of glycogen synthase by the Ca2+- and phospholipid-activated protein kinase (protein kinase C).
1984
Role of protein kinase C in diacylglycerol-mediated induction of ornithine decarboxylase and reduction of epidermal growth factor binding.
1985
Protein kinase C phosphorylates the inhibitory guanine‐nucleotide‐binding regulatory component and apparently suppresses its function in hormonal inhibition of adenylate cyclase
1985 StandoutNobel
Insulin-like effects of epidermal growth factor and insulin-like growth factor-I on [3H]2-deoxyglucose uptake, diacylglycerol generation and protein kinase C activation in BC3H-1 myocytes
1989
A single form of protein kinase C is expressed in bovine adrenocortical tissue, as compared to four chromatographically resolved isozymes in rat brain
1987
Works of J E Niedel being referenced
Transcription interruption may be a common mechanism of c-myc regulation during HL-60 differentiation
1988
Cyclic Nucleotide-induced Maturation of Human Promyelocytic Leukemia Cells
1982
Formyl peptide chemotactic receptor. Evidence for an active proteolytic fragment.
1983
Quantitative measurement of sn-1,2-diacylglycerols present in platelets, hepatocytes, and ras- and sis-transformed normal rat kidney cells.
1986
Phorbol diesters and dioctanoylglycerol stimulate accumulation of both diacylglycerols and alkylacylglycerols in human neutrophils.
1988
Cytochalasin B enhancement of the diacylglycerol response in formyl peptide-stimulated neutrophils.
1986
Vinculin, a cytoskeletal substrate of protein kinase C.
1983
Phorbol Diesters and Cellular Differentiation<xref ref-type="fn" rid="FN5">5</xref>
1984
Diacylglycerols mimic phorbol diester induction of leukemic cell differentiation.
1985
Diacylglycerol accumulation and superoxide anion production in stimulated human neutrophils.
1987
Dioctanoylglycerol and phorbol esters regulate transcription of c-myc in human promyelocytic leukemia cells.
1988
Covalent affinity labeling of the formyl peptide chemotactic receptor.
1980
Conversion of a gonadotropin-releasing hormone antagonist to an agonist
1982 Nature
Distinct patterns of expression of different protein kinase C mRNAs in rat tissues
1987
Induction of myeloid differentiation of HL-60 cells with naphthalene sulfonamide calmodulin antagonists.
1986
Pertussis toxin inhibits chemotactic peptide-stimulated generation of inositol phosphates and lysosomal enzyme secretion in human leukemic (HL-60) cells.
1985
Possible mechanism of phorbol diester-induced maturation of human promyelocytic leukemia cells.
1984
Quantitative measurement of sn-1,2-diacylglycerols
1987
Formyl Peptide Chemotactic Receptors of Leukocytes and Macrophages
1980
Dynamics of the Diradylglycerol Responses of Stimulated Phagocytes
1989
Receptor-Mediated Internalization of Fluorescent Chemotactic Peptide by Human Neutrophils
1979 Science
Phorbol diester receptor copurifies with protein kinase C.
1983
B cell activation. IV. Induction of cell membrane depolarization and hyper-I-A expression by phorbol diesters suggests a role for protein kinase C in murine B lymphocyte activation.
1984
Differential stimulation of the respiratory burst and lysosomal enzyme secretion in human polymorphonuclear leukocytes by synthetic diacylglycerols.
1986
Receptor-mediated uptake and degradation of 125I-chemotactic peptide by human neutrophils.
1979
Cytosolic calcium regulates phorbol diester binding affinity in intact phagocytes.
1986
A subpopulation of cultured human promyelocytic leukemia cells (HL-60) displays the formyl peptide chemotactic receptor.
1980
Diacylglycerol mass measurements in stimulated HL-60 phagocytes.
1987