Citation Impact
Citing Papers
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
A role for DNA-mediated charge transport in regulating p53: Oxidation of the DNA-bound protein from a distance
2007
ZBTB1 is a determinant of lymphoid development
2011 StandoutNobel
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
2010 StandoutNobel
The regulation of cellular metabolism by tumor suppressor p53
2013
Tp53-induced Glycolysis and Apoptosis Regulator (TIGAR) Protects Glioma Cells from Starvation-induced Cell Death by Up-regulating Respiration and Improving Cellular Redox Homeostasis
2012
Genome-wide features of neuroendocrine regulation in Drosophila by the basic helix-loop-helix transcription factor DIMMED
2015 StandoutNobel
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
ATM-dependent suppression of stress signaling reduces vascular disease in metabolic syndrome
2006
Linking functional decline of telomeres, mitochondria and stem cells during ageing
2010 Nature
The DNA-damage response in human biology and disease
2009 StandoutNature
Regulation of AIF expression by p53
2006
The role of nuclear lamin B1 in cell proliferation and senescence
2011
The General Transcription Machinery and General Cofactors
2006
X4 and R5 HIV-1 Have Distinct Post-entry Requirements for Uracil DNA Glycosylase during Infection of Primary Cells
2010 StandoutNobel
Telomerase Reverse Transcriptase Delays Aging in Cancer-Resistant Mice
2008
mTOR Signaling in Growth Control and Disease
2012 Standout
MYC on the Path to Cancer
2012 Standout
A view on drug resistance in cancer
2019 StandoutNature
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
Gain of Function of a p53 Hot Spot Mutation in a Mouse Model of Li-Fraumeni Syndrome
2004
p53 Regulates Hematopoietic Stem Cell Quiescence
2009
TIGAR, a p53-Inducible Regulator of Glycolysis and Apoptosis
2006 Standout
p53 polymorphisms: cancer implications
2009
p53 and metabolism
2009
HIF-Dependent Antitumorigenic Effect of Antioxidants In Vivo
2007 StandoutNobel
The genetics of ageing
2010 StandoutNature
Molecular mechanisms of drug resistance
2005
When mutants gain new powers: news from the mutant p53 field
2009
Hallmarks of aging: An expanding universe
2023 Standout
HIF-1 mediates metabolic responses to intratumoral hypoxia and oncogenic mutations
2013 StandoutNobel
p53: new roles in metabolism
2007
A role for mitochondria in NLRP3 inflammasome activation
2010 StandoutNature
Increased Oxidative Metabolism in the Li–Fraumeni Syndrome
2013
Cellular Senescence in Cancer and Aging
2007 Standout
Clearance of p16Ink4a-positive senescent cells delays ageing-associated disorders
2011 StandoutNature
Transcriptional activities of mutant p53: When mutations are more than a loss
2004
Axis of ageing: telomeres, p53 and mitochondria
2012
ROS and p53: A versatile partnership
2008
Autophagy: Renovation of Cells and Tissues
2011 Standout
ROS Function in Redox Signaling and Oxidative Stress
2014 Standout
New plays in the p53 theater
2010
Hydrogen Peroxide Sensing and Signaling
2007
mTOR Signaling in Growth, Metabolism, and Disease
2017 Standout
Blinded by the Light: The Growing Complexity of p53
2009 Standout
The dark side of a tumor suppressor: anti-apoptotic p53
2008
ROS as signalling molecules: mechanisms that generate specificity in ROS homeostasis
2007 Standout
Defective CFTR induces aggresome formation and lung inflammation in cystic fibrosis through ROS-mediated autophagy inhibition
2010
PRIMA-1 Reactivates Mutant p53 by Covalent Binding to the Core Domain
2009
Anti‐aging activity of the Ink4/Arf locus
2009
The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
2010
p53 in health and disease
2007 Standout
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
The Role of Chromatin during Transcription
2007 Standout
Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System
2014 StandoutNobel
Modulation of intracellular ROS levels by TIGAR controls autophagy
2009
The ATM protein kinase and cellular redox signaling: beyond the DNA damage response
2011
The Inflammasomes
2010 Standout
Delayed ageing through damage protection by the Arf/p53 pathway
2007 Nature
The role of senescent cells in ageing
2014 StandoutNature
The Hallmarks of Aging
2013 Standout
Growth-Inhibitory and Tumor- Suppressive Functions of p53 Depend on Its Repression of CD44 Expression
2008
p53 Target Genes Sestrin1 and Sestrin2 Connect Genotoxic Stress and mTOR Signaling
2008
Evolution and Functions of Long Noncoding RNAs
2009 Standout
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Naturally occurring p16Ink4a-positive cells shorten healthy lifespan
2016 StandoutNature
Targeting cancer cells by ROS-mediated mechanisms: a radical therapeutic approach?
2009 Standout
Transcriptional Paradigms in Mammalian Mitochondrial Biogenesis and Function
2008
Frailty in elderly people
2013 Standout
Spatial partitioning of the regulatory landscape of the X-inactivation centre
2012 StandoutNature
The imprinted Air ncRNA is an atypical RNAPII transcript that evades splicing and escapes nuclear export
2006
Autophagy in immunity and inflammation
2011 StandoutNature
p53 and disease: when the guardian angel fails
2006
The first 30 years of p53: growing ever more complex
2009 Standout
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
2009 StandoutNature
Glutaminase 2, a novel p53 target gene regulating energy metabolism and antioxidant function
2010
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Pomegranate fruit juice for chemoprevention and chemotherapy of prostate cancer
2005 Standout
Phosphate-activated glutaminase (GLS2), a p53-inducible regulator of glutamine metabolism and reactive oxygen species
2010
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
2014 Standout
Metabolic reprogramming and cancer progression
2020 StandoutScience
Structure of P-Glycoprotein Reveals a Molecular Basis for Poly-Specific Drug Binding
2009 StandoutScience
Antioxidants Accelerate Lung Cancer Progression in Mice
2014
The Two Faces of Reactive Oxygen Species in Cancer
2016
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
Inhibition of Pyruvate Kinase M2 by Reactive Oxygen Species Contributes to Cellular Antioxidant Responses
2011 Science
Photopharmacology: Beyond Proof of Principle
2014 StandoutNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Sestrins Inhibit mTORC1 Kinase Activation through the GATOR Complex
2014
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
“Inverse Drug Discovery” Strategy To Identify Proteins That Are Targeted by Latent Electrophiles As Exemplified by Aryl Fluorosulfates
2017 StandoutNobel
The Arf/p53 Pathway in Cancer and Aging
2008
Fluorodeoxyuridine Modulates Cellular Expression of the DNA Base Excision Repair Enzyme Uracil-DNA Glycosylase
2006
Works of J. E. Kravchenko being referenced
Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway
2008
Novel gain of function activity of p53 mutants: activation of the dUTPase gene expression leading to resistance to 5-fluorouracil
2002
Androgen regulates apoptosis induced by TNFR family ligands via multiple signaling pathways in LNCaP
2005
The antioxidant function of the p53 tumor suppressor
2005
Transcription of mammalian messenger RNAs by a nuclear RNA polymerase of mitochondrial origin
2005 Nature