Citation Impact
Citing Papers
Association of PD-1, PD-1 Ligands, and Other Features of the Tumor Immune Microenvironment with Response to Anti–PD-1 Therapy
2014 Standout
CTLA4 blockade expands FoxP3+ regulatory and activated effector CD4+ T cells in a dose-dependent fashion
2008 StandoutNobel
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
Enterocolitis in Patients With Cancer After Antibody Blockade of Cytotoxic T-Lymphocyte–Associated Antigen 4
2006
The gut microbiota and host health: a new clinical frontier
2015 Standout
The role of bile acids in functional GI disorders
2014
Bile acid transporters
2009
Multidrug resistance in cancer: role of ATP–dependent transporters
2002 Standout
Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis
2005 Standout
Gut Microbiota Regulates Bile Acid Metabolism by Reducing the Levels of Tauro-beta-muricholic Acid, a Naturally Occurring FXR Antagonist
2013 Standout
Single‐institution experience with ipilimumab in advanced melanoma patients in the compassionate use setting
2010 StandoutNobel
Microbiota Modification with Probiotics Induces Hepatic Bile Acid Synthesis via Downregulation of the Fxr-Fgf15 Axis in Mice
2014
Pleiotropic Roles of Bile Acids in Metabolism
2013
Changes of Intestinal Functions in Liver Cirrhosis
2016 Standout
Liver disease caused by failure to racemize trihydroxycholestanoic acid: Gene mutation and effect of bile acid therapy
2003
Bowel Disorders
2016 Standout
REGULATION OF BILE ACID BIOSYNTHESIS
1999
Cystic fibrosis
2016 Standout
Accurate enzymatic measurement of fecal bile acids in patients with malabsorption
2003
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
Pancreatic enzyme replacement therapy for people with cystic fibrosis
2014
Identification of a new inborn error in bile acid synthesis: mutation of the oxysterol 7alpha-hydroxylase gene causes severe neonatal liver disease.
1998
Detection of Δ4-3-oxo-steroid 5β-reductase deficiency by LC–ESI-MS/MS measurement of urinary bile acids
2012
Identification of a Bile Acid-responsive Element in the Human Ileal Bile Acid-binding Protein Gene
1999
BILE ACID TRANSPORT
1999
The bile acid synthetic gene 3β-hydroxy-Δ5-C27-steroid oxidoreductase is mutated in progressive intrahepatic cholestasis
2000
Determination of progesterone and 17-hydroxyprogesterone by high performance liquid chromatography after pre-column derivatization with 4,4-difluoro-5,7-dimethyl-4-bora-3a,4a- diaza-s-indacene-3-propionohydrazide
1998
INBORN ERRORS OF BILE ACID BIOSYNTHESIS AND TRANSPORT
1999
A Regulatory Cascade of the Nuclear Receptors FXR, SHP-1, and LRH-1 Represses Bile Acid Biosynthesis
2000 Standout
Role of Bile Acids and Bile Acid Receptors in Metabolic Regulation
2009
Increased Bile Acid Biosynthesis Is Associated With Irritable Bowel Syndrome With Diarrhea
2012
Reactive oxygen species and peroxisomes: Struggling for balance
2009
Indigenous Bacteria from the Gut Microbiota Regulate Host Serotonin Biosynthesis
2015 Standout
Targeted Disruption of the Nuclear Receptor FXR/BAR Impairs Bile Acid and Lipid Homeostasis
2000 Standout
Mendelian randomization: genetic anchors for causal inference in epidemiological studies
2014 Standout
Lipids and lipid-based formulations: optimizing the oral delivery of lipophilic drugs
2007 Standout
Diet–microbiota interactions as moderators of human metabolism
2016 StandoutNature
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
2016 Standout
Diet rapidly and reproducibly alters the human gut microbiome
2013 StandoutNature
Coordinate Transcriptional Regulation of Transport and Metabolism
2005
Farnesoid X nuclear receptor ligand obeticholic acid for non-cirrhotic, non-alcoholic steatohepatitis (FLINT): a multicentre, randomised, placebo-controlled trial
2014 Standout
Negative regulators of T‐cell activation: potential targets for therapeutic intervention in cancer, autoimmune disease, and persistent infections
2009 StandoutNobel
The blockade of immune checkpoints in cancer immunotherapy
2012 Standout
The serum protein α2–Heremans-Schmid glycoprotein/fetuin-A is a systemically acting inhibitor of ectopic calcification
2003 Standout
Intestinal Crosstalk between Bile Acids and Microbiota and Its Impact on Host Metabolism
2016 Standout
Sex differences in immune responses
2016 Standout
Mendelian randomization: prospects, potentials, and limitations
2004
Characterization, cDNA Cloning, and Functional Expression of Mouse Heal Sodium-Dependent Bile Acid Transporter
1999
New insights into bile acid transport
1998
Drug Transport and Targeting
2002
Bile Acids: Chemistry, Pathochemistry, Biology, Pathobiology, and Therapeutics
2008
Bile acid biosynthesis
1992
Disruption of the Oxysterol 7α-Hydroxylase Gene in Mice
2000
Stem cell-derived polarized hepatocytes
2020 StandoutNobel
The pros, cons, and many unknowns of probiotics
2019 Standout
Gut microbiota in human metabolic health and disease
2020 Standout
The Complex Role of Estrogens in Inflammation
2007 Standout
The Golden Age of Transfer Hydrogenation
2015 Standout
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
Christian Raetz: Scientist and Friend Extraordinaire
2013 StandoutNobel
Deciphering the nuclear bile acid receptor FXR paradigm
2010
Identification of Farnesoid X Receptor β as a Novel Mammalian Nuclear Receptor Sensing Lanosterol
2003 StandoutNobel
Molecular Control of Immune/Inflammatory Responses: Interactions Between Nuclear Factor-κB and Steroid Receptor-Signaling Pathways
1999
The Enzymes, Regulation, and Genetics of Bile Acid Synthesis
2003 Standout
Apical Sodium Dependent Bile Acid Transporter (ASBT, SLC10A2): A Potential Prodrug Target
2006
The B7 Family and Cancer Therapy: Costimulation and Coinhibition
2007 StandoutNobel
Mutations in the MDR 3 gene cause progressive familial intrahepatic cholestasis
1998
Peroxisome biogenesis disorders: Biological, clinical and pathophysiological perspectives
2013
Cell intrinsic mechanisms of T‐cell inhibition and application to cancer therapy
2008 StandoutNobel
Bile Salt Transporters: Molecular Characterization, Function, and Regulation
2003
Immunologic and clinical effects of antibody blockade of cytotoxic T lymphocyte-associated antigen 4 in previously vaccinated cancer patients
2008 StandoutNobel
Management of Immune-Related Adverse Events and Kinetics of Response With Ipilimumab
2012 Standout
Genetic identification of HSD-1, a conserved steroidogenic enzyme that directs larval development inCaenorhabditis elegans
2008 StandoutNobel
LXRS AND FXR: The Yin and Yang of Cholesterol and Fat Metabolism
2005
BODIPY Dyes and Their Derivatives: Syntheses and Spectroscopic Properties
2007 Standout
Antiinflammatory Action of Glucocorticoids — New Mechanisms for Old Drugs
2005 Standout
Bile Acids: Natural Ligands for an Orphan Nuclear Receptor
1999 StandoutScience
Direct organocatalytic stereoselective transfer hydrogenation of conjugated olefins of steroids
2013
Reactive Oxygen Species in Metabolic and Inflammatory Signaling
2018 Standout
Host-Gut Microbiota Metabolic Interactions
2012 StandoutScience
Functional Significance of Cell Volume Regulatory Mechanisms
1998 Standout
A Pilot Trial of CTLA-4 Blockade with Human Anti-CTLA-4 in Patients with Hormone-Refractory Prostate Cancer
2007 StandoutNobel
Taurine: Its Biological Role and Clinical Implications
1985
Unique double-ring structure of the peroxisomal Pex1/Pex6 ATPase complex revealed by cryo-electron microscopy
2015 StandoutNobel
Identification of a Nuclear Receptor for Bile Acids
1999 StandoutScience
Maternal-Fetal Calcium and Bone Metabolism During Pregnancy, Puerperium, and Lactation*
1997
Works of J E Heubi being referenced
Bile Acid Synthetic Defects and Liver Disease
2000
Enteral metronidazole for the prevention of graft versus host disease in pediatric marrow transplant recipients: results of a pilot study
2004
Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2).
1997
Adaptive response of the enterohepatic circulation of bile acids to extrahepatic cholestasis
1996
Intestinal calcium absorption of women during lactation and after weaning
1996
Delta 4-3-oxosteroid 5 beta-reductase deficiency described in identical twins with neonatal hepatitis. A new inborn error in bile acid synthesis.
1988
246 EUR-1008 (a new pancraetic enzyme product, PEP) was shown to be safe and effective in cystic fibrosis (CF) patients with exocrine pancreatic insufficiency (EPI)
2007
Switching CF patients from previous pancreatic enzyme replacement therapy to ZENPEP™ (pancrelipase delayed-release capsules) improves symptom control of exocrine pancreatic insufficiency (EPI)
2010
Glucocorticoids upregulate taurocholate transport by ileal brush-border membrane
1997
Downregulation of taurocholate transport by ileal BBM and liver BLM in biliary-diverted rats
1994
A PEX10 defect in a patient with no detectable defect in peroxisome assembly or metabolism in cultured fibroblasts
2008
Postnatal development of intestinal bile salt transport in the guinea pig
1982