Citation Impact
Citing Papers
Preferential Generation of Follicular B Helper T Cells from Foxp3 + T Cells in Gut Peyer's Patches
2009 StandoutScienceNobel
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
Innate and Adaptive Immunity Cooperate Flexibly to Maintain Host-Microbiota Mutualism
2009 StandoutScienceNobel
Predominant Autoantibody Production by Early Human B Cell Precursors
2003 StandoutScience
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Role of CXCR5 and CCR7 in Follicular Th Cell Positioning and Appearance of a Programmed Cell Death Gene-1High Germinal Center-Associated Subpopulation
2007
Molecular mechanisms for B lymphocyte selection: induction and regulation of antigen-receptor-mediated apoptosis of mature B cells in normal mice and their defect in autoimmunity-prone mice
1994 StandoutNobel
Competition for follicular niches excludes self-reactive cells from the recirculating B-cell repertoire
1994 Nature
Anti‐immunoglobulins induce death by apoptosis in WEHI‐231 B lymphoma cells
1990
Positive and negative selection events during B lymphopoiesis
1995
ICOS co-stimulatory receptor is essential for T-cell activation and function
2001 StandoutNatureNobel
Clonal deletion of B lymphocytes in a transgenic mouse bearing anti-MHC class I antibody genes
1989 Nature
Origin of Murine B Cell Lineages
1993
CD22 blockade restores homeostatic microglial phagocytosis in ageing brains
2019 StandoutNatureNobel
Marginal-zone B cells
2002
Control of B-cell responses by Toll-like receptors
2005 Nature
Differential activation of transcription factors induced by Ca2+ response amplitude and duration
1997 Nature
Cells’ Perception of Position in a Concentration Gradient
1998 StandoutNobel
T and B cell Tolerance and Responses to Viral Antigens in Transgenic Mice: Implications for the Pathogenesis of Autoimmune versus Immunopathological Disease
1991
Regulatory T Cells
2000 StandoutNobel
Stable Expression and Somatic Hypermutation of Antibody V Regions in B-Cell Developmental Pathways
1989
Role of HIF-1α in hypoxia-mediated apoptosis, cell proliferation and tumour angiogenesis
1998 StandoutNatureNobel
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
ATP11C is critical for the internalization of phosphatidylserine and differentiation of B lymphocytes
2011
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
Different Nuclear Signals Are Activated by the B Cell Receptor during Positive Versus Negative Signaling
1997
The level of CD8 expression can determine the outcome of thymic selection
1992 StandoutNobel
Peripheral Tolerance in Transgenic Mice: Tolerance to Class II MHC and non‐MHC Transgene Antigens
1991
Positive Selection from Newly Formed to Marginal Zone B Cells Depends on the Rate of Clonal Production, CD19, and btk
2000
Tolerance, Danger, and the Extended Family
1994 Standout
CD22 is a negative regulator of B-cell receptor signalling
1997 Nobel
Follicular B helper T cells in antibody responses and autoimmunity
2005
Immature B cells from human and mouse bone marrow can change their surface light chain expression
1995
Immunoglobulin heavy chain expression shapes the B cell receptor repertoire in human B cell development
2001
Gene Switching and the Stability of Odorant Receptor Gene Choice
2004 StandoutNobel
Expression of anti-DNA immunoglobulin transgenes in non-autoimmune mice
1991 Nature
CD4: Collaborator in immune recognition and HIV infection
1990 StandoutNobel
T‐Cell Tolerance in Transgenic Mice Expressing Major Histocompatibility Class I Molecules in Defined Tissues
1989
Signaling thresholds and interclonal competition in preimmune B‐cell selection
1997
T Cell–Mediated Elimination of B7.2 Transgenic B Cells
1997 StandoutNobel
CD21highIgMhigh Splenic B Cells Enriched in the Marginal Zone: Distinct Phenotypes and Functions
1999
Expansion or Elimination of B Cells In Vivo: Dual Roles for CD40- and Fas (CD95)-Ligands Modulated by the B Cell Antigen Receptor
1996
Toll-like receptors: balancing host resistance with immune tolerance
2003
Antigen-induced exclusion from follicles and anergy are separate and complementary processes that influence peripheral B cell fate
1995
Continued RAG expression in late stages of B cell development and no apparent re-induction after immunizion
1999 Nature
Hypermutation generating the sheep immunoglobulin repertoire is an antigen-independent process
1995
Acquisition of immunologic self-tolerance
1989
B-cell apoptosis induced by antigen receptor crosslinking is blocked by a T-cell signal through CD40
1993 StandoutNatureNobel
In situ class switching and differentiation to IgA-producing cells in the gut lamina propria
2001 StandoutNatureNobel
Peripheral deletion of self-reactive B cells
1991 Nature
Cell-permeant caged InsP3 ester shows that Ca2+ spike frequency can optimize gene expression
1998 StandoutNatureNobel
Virus-induced autoantibody response to a transgenic viral antigen
1990 StandoutNatureNobel
The P4-type ATPase ATP11C is essential for B lymphopoiesis in adult bone marrow
2011 StandoutNobel
Self-Tolerance Checkpoints in B Lymphocyte Development
1995
Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice
1992 StandoutNatureNobel
Clonal selection and learning in the antibody system
1996 StandoutNature
Deletion of SHIP or SHP-1 Reveals Two Distinct Pathways for Inhibitory Signaling
1997
A Dominant Complement Fixation Pathway for Pneumococcal Polysaccharides Initiated by SIGN-R1 Interacting with C1q
2006 StandoutNobel
Abnormal B lymphocyte delevopment, activation, and differentiation in mice that lack or overexpress the CD19 signal transduction molecule
1995
Antigen-receptor cross-linking induces peritoneal B-cell apoptosis in normal but not autoimmunity-prone mice
1994 StandoutNobel
CD95 (Fas)-dependent elimination of self-reactive B cells upon interaction with CD4+T cells
1995 Nature
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
Dendritic cells and the control of immunity
1998 StandoutNatureNobel
Cellular and Molecular Mechanisms of B Lymphocyte Tolerance
1992
Transgenic Mice and Analysis of B-Cell Tolerance
1992
The role of the bcl-2/ced-9 gene family in cancer and general implications of defects in cell death control for tumourigenesis and resistance to chemotherapy
1997
Elimination of self-reactive B lymphocytes proceeds in two stages: Arrested development and cell death
1993
The site and stage of anti-DNA B-cell deletion
1995 Nature
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
Extrathymic positive selection of αβ T-cell precursors in nude mice
1992 StandoutNatureNobel
Abrogation of TGFβ Signaling in T Cells Leads to Spontaneous T Cell Differentiation and Autoimmune Disease
2000
Aire regulates negative selection of organ-specific T cells
2003
AID is required to initiate Nbs1/γ-H2AX focus formation and mutations at sites of class switching
2001 StandoutNatureNobel
Clonal anergy induced in mature Vβ6+ T lymphocytes on immunizing Mls-1b mice with Mls-1a expressing cells
1989 Nature
The bcl-2 gene product inhibits clonal deletion of self-reactive B lymphocytes in the periphery but not in the bone marrow.
1993 StandoutNobel
Receptor editing in self-reactive bone marrow B cells.
1993
Repression of B7.2 on Self-reactive B Cells Is Essential to Prevent Proliferation and Allow Fas-mediated Deletion by CD4+ T Cells
1998 StandoutNobel
Breakdown of B cell tolerance in a mouse model of systemic lupus erythematosus.
1995
A transgenic model of autoimmune hemolytic anemia.
1992 StandoutNobel
Hyperresponsive B Cells in CD22-Deficient Mice
1996 Science
Peripheral Selection of the T Cell Repertoire
1991 Science
A Nondeletional Mechanism of Thymic Self Tolerance
1989 StandoutScienceNobel
Receptor editing: an approach by autoreactive B cells to escape tolerance.
1993
Induction of classical transplantation tolerance in the adult.
1989
C3d of Complement as a Molecular Adjuvant: Bridging Innate and Acquired Immunity
1996 Science
Homeostasis and Self-Tolerance in the Immune System: Turning Lymphocytes off
1998 Science
Immunoglobulin signal transduction guides the specificity of B cell-T cell interactions and is blocked in tolerant self-reactive B cells.
1994
Viral Superantigen Drives Extrafollicular and Follicular B Cell Differentiation Leading to Virus-specific Antibody Production
1997
Clonal Deletion Versus Clonal Anergy: The Role of the Thymus in Inducing Self Tolerance
1990 StandoutScienceNobel
Influence of immunoglobulin heavy- and light-chain expression on B-cell differentiation.
1994
Cross-linking of membrane immunoglobulin D, in the absence of T cell help, kills mature B cells in vivo.
1995
RAG-2-deficient blastocyst complementation: an assay of gene function in lymphocyte development.
1993
THE ROLE OF COMPLEMENT AND COMPLEMENT RECEPTORS IN INDUCTION AND REGULATION OF IMMUNITY
1998
T Cell Studies in a Peptide-Induced Model of Systemic Lupus Erythematosus
2001 StandoutNobel
Contribution of Receptor Editing to the Antibody Repertoire
2001 Science
Production, specificity, and functionality of monoclonal antibodies to specific peptide–major histocompatibility complex class II complexes formed by processing of exogenous protein
1997
Expression Levels of B Cell Surface Immunoglobulin Regulate Efficiency of Allelic Exclusion and Size of Autoreactive B-1 Cell Compartment
1999 StandoutNobel
The fate of self-reactive B cells depends primarily on the degree of antigen receptor engagement and availability of T cell help.
1996
B cells acquire antigen from target cells after synapse formation
2001 Nature
B lymphocytes may escape tolerance by revising their antigen receptors.
1993
Developmental regulation of the Bcl-2 protein and susceptibility to cell death in B lymphocytes.
1994
Oral administration of lipopolysaccharides activates B-1 cells in the peritoneal cavity and lamina propria of the gut and induces autoimmune symptoms in an autoantibody transgenic mouse.
1994 StandoutNobel
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
B Cell Development Pathways
2001
Resting and anergic B cells are defective in CD28-dependent costimulation of naive CD4+ T cells.
1994
Most peripheral B cells in mice are ligand selected.
1991
Transport of Peptide-MHC Class II Complexes in Developing Dendritic Cells
2000 StandoutScienceNobel
"Diabodies": small bivalent and bispecific antibody fragments.
1993 StandoutNobel
Seppuku and Autoimmunity
1992 StandoutScienceNobel
T-Independent Immune Response: New Aspects of B Cell Biology
2000 StandoutScienceNobel
Receptor Selection in B and T Lymphocytes
2000
PD-1 immunoreceptor inhibits B cell receptor-mediated signaling by recruiting src homology 2-domain-containing tyrosine phosphatase 2 to phosphotyrosine
2001 StandoutNobel
T Cell Accumulation in B Cell Follicles Is Regulated by Dendritic Cells and Is Independent of B Cell Activation
2003
Maintenance of in Vivo Tolerance by Persistence of Antigen
1992 StandoutScienceNobel
Anergic self-reactive B cells present self antigen and respond normally to CD40-dependent T-cell signals but are defective in antigen-receptor-mediated functions.
1994
Prevention of Scrapie Pathogenesis by Transgenic Expression of Anti-Prion Protein Antibodies
2001 Science
Concurrent engagement of CD40 and the antigen receptor protects naive and memory human B cells from APO-1/Fas-mediated apoptosis.
1996
Small B cells as antigen-presenting cells in the induction of tolerance to soluble protein antigens.
1992
Somatic Hypermutation in the Absence of DNA-Dependent Protein Kinase Catalytic Subunit (DNA-Pkcs) or Recombination-Activating Gene (Rag)1 Activity
2000
Genes, pathways and checkpoints in lymphocyte development and homeostasis
2005
Adjuvant-Enhanced Antibody Responses in the Absence of Toll-Like Receptor Signaling
2006 StandoutScienceNobel
Tolerant B Lymphocytes Acquire Resistance to Fas-mediated Apoptosis after Treatment with Interleukin 4 but Not after Treatment with Specific Antigen Unless a Surface Immunoglobulin Threshold Is Exceeded
1998
Programmed cell death by bcl-2-dependent and independent mechanisms in B lymphoma cells.
1993
Inducible Costimulator Protein (Icos) Controls T Helper Cell Subset Polarization after Virus and Parasite Infection
2000
Human anti-self antibodies with high specificity from phage display libraries.
1993
Works of J. Crosbie being referenced
Clonal Silencing of Self-reactive B Lymphocytes in a Transgenic Mouse Model
1989
Altered immunoglobulin expression and functional silencing of self-reactive B lymphocytes in transgenic mice
1988 Nature
Self Tolerance in the B‐Cell Repertoire
1991
Induction of self-tolerance in mature peripheral B lymphocytes
1989 Nature
Elimination from peripheral lymphoid tissues of self-reactive B lymphocytes recognizing membrane-bound antigens
1991 Nature
Immunoglobulin M and D antigen receptors are both capable of mediating B lymphocyte activation, deletion, or anergy after interaction with specific antigen.
1992
B Cell Receptor–independent Stimuli Trigger Immunoglobulin (Ig) Class Switch Recombination and Production of IgG Autoantibodies by Anergic Self-Reactive B Cells
2003
Induction of Self-Rolerance in T Cells But Not B Cells of Transgenic Mice Expressing Little Self Antigen
1991 Science