Citation Impact
Citing Papers
Systematic Genetic Analysis with Ordered Arrays of Yeast Deletion Mutants
2001 StandoutScience
A "Silent" Polymorphism in the MDR 1 Gene Changes Substrate Specificity
2006 StandoutScience
miR-15 and miR-16 induce apoptosis by targeting BCL2
2005 Standout
Soluble interleukin-2 receptor in Crohn's disease: relation of serum concentrations to disease activity.
1990
Phase I and pharmacokinetic study of paclitaxel in combination with biricodar, a novel agent that reverses multidrug resistance conferred by overexpression of both MDR1 and MRP.
1998
Multidrug resistance in cancer: role of ATP–dependent transporters
2002 Standout
Quantitative reverse transcriptase-polymerase chain reaction measured expression of MDR1 and MRP in primary breast carcinoma.
1998
Expression of the multidrug resistance proteins MRP2 and MRP3 in human hepatocellular carcinoma
2001
MRP and MDR1 gene expression in primary breast carcinomas.
1996
Chitosan nanoparticles as delivery systems for doxorubicin
2001
Multidrug Resistance in Breast Cancer: a Meta-analysis of MDR1/gp170 Expression and Its Possible Functional Significance
1997
The Concept of Synthetic Lethality in the Context of Anticancer Therapy
2005 StandoutNobel
Transplantation of Normal and Leukemic Human Bone Marrow into Immune‐Deficient Mice: Development of Animal Models for Human Hematopoiesis
1991
P-glycoproteins in pathology: The multidrug resistance gene family in humans
1990
P-glycoprotein: from genomics to mechanism
2003
Disruption of the mouse mdr1a P-glycoprotein gene leads to a deficiency in the blood-brain barrier and to increased sensitivity to drugs
1994 Standout
Inhibition of lysosomal acid sphingomyelinase by agents which reverse multidrug resistance
1995
From amplification to function: the case of the MDR1 gene
1992
Impaired expansion of mouse B cell progenitors lacking Btk
1995
The prognostic significance of proliferating cell nuclear antigen, epidermal growth factor receptor, andmdr gene expression in colorectal cancer
1993
Patterns of cross-resistance in a multidrug-resistant small-cell lung carcinoma cell line
1990
Homozygous disruption of the murine MDR2 P-glycoprotein gene leads to a complete absence of phospholipid from bile and to liver disease
1993 Standout
Choosing anticancer drug targets in the postgenomic era
1999 StandoutNobel
PEO-PPO Block Copolymers for Passive Micellar Targeting and Overcoming Multidrug Resistance in Cancer Therapy
2011
A cell initiating human acute myeloid leukaemia after transplantation into SCID mice
1994 StandoutNature
Immunohistochemical detection of multidrug resistance associated P-glycoprotein in tumour and stromal cells of human cancers
1990
Multidrug resistance (mdr) genes in human cancer
1991
Colocalization of X-Linked Agammaglobulinemia and X-Linked Immunodeficiency Genes
1993 Science
Isolation and Function of Human Dendritic Cells
1994
Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer
2004 Standout
Viral interference with antibody and complement
1998
Developmental regulation of MHC class II transport in mouse dendritic cells
1997 StandoutNatureNobel
Role of the retinoblastoma protein in the pathogenesis of human cancer.
1997 StandoutNobel
Expression and activity of P-glycoprotein, a multidrug efflux pump, in human hematopoietic stem cells
1991
Crohn's disease
1987
Inflammatory Bowel Disease
1991 Standout
Complete cDNA sequences encoding the Chinese hamster P-glycoprotein gene family
1991
Expression of P-Glycoprotein in High-Grade Osteosarcomas in Relation to Clinical Outcome
1995
The biology of the P-glycoproteins
1995
Characterization of Phosphorylation-defective Mutants of Human P-glycoprotein Expressed in Mammalian Cells
1996
P-Glycoprotein gene (MDR1) cDNA from human adrenal: Normal P-glycoprotein carries Gly185 with an altered pattern of multidrug resistance
1989
Eukaryotic DNA topoisomerases I
1995
Protein modules and signalling networks
1995 StandoutNature
Incidence of P-glycoprotein overexpression and multidrug resistance (MDR) reversal in adult soft tissue sarcoma
2000
Apoptosis
2002 Standout
Clinical trials of p-glycoprotein reversal in solid tumours
1996
Quantitative expression patterns of multidrug‐resistance P‐glycoprotein (MDR1) and differentially spliced cystic‐fibrosis transmembrane‐conductance regulator mRNA transcripts in human epithelia
1992
P-glycoprotein expression at diagnosis may not be a primary mechanism of therapeutic failure in childhood rhabdomyosarcoma.
1996
Multidrug Resistance: A Novel Class of Membrane-Associated Transport Proteins is Identified
1991
Antigen-induced apoptotic death of Ly-1 B cells responsible for autoimmune disease in transgenic mice
1992 StandoutNatureNobel
Complement
2001 Standout
Expression of the multidrug resistance-associated protein (MRP) gene in primary non-small-cell lung cancer
1996
Genomic Aberrations and Survival in Chronic Lymphocytic Leukemia
2000 Standout
Kaposi's Sarcoma–Associated Herpesvirus-Like DNA Sequences in AIDS-Related Body-Cavity–Based Lymphomas
1995 Standout
p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
1993 Standout
A common E2F-1 and p73 pathway mediates cell death induced by TCR activation
2000 StandoutNatureNobel
Effects of Uracil Incorporation, DNA Mismatches, and Abasic Sites on Cleavage and Religation Activities of Mammalian Topoisomerase I
1997 StandoutNobel
Multidrug-Resistant Gene Expression in Small-Cell Lung Cancer
1997
Mutations in the Cystic Fibrosis Gene in Patients with Congenital Absence of the Vas Deferens
1995 Standout
Stem cell-derived polarized hepatocytes
2020 StandoutNobel
P-glycoprotein, multidrug resistance and tumor progression
1994
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
2001 Standout
Function and Regulation of the Human Multidrug Resistance Gene
1992
Structural Aspects and Heterogeneity of Immunoglobulin Fc Receptors
1981
Biologic Correlates of 18Fluorodeoxyglucose Uptake in Human Breast Cancer Measured by Positron Emission Tomography
2002 StandoutNobel
Development and Physiology of LY‐1 B and its Human Homolog, LEU‐1 B
1986
The Bcl-2 Protein Family: Arbiters of Cell Survival
1998 StandoutScience
Multidrug resistance-associated protein in acute myeloid leukemia: No impact on treatment outcome.
1997
Distribution of multi-drug resistance-associated P-glycoprotein in normal and neoplastic human tissues
1990
Selective killing of transformed cells by cyclin/cyclin-dependent kinase 2 antagonists
1999 StandoutNobel
Multiple genetic lesions in acquired immunodeficiency syndrome-related non-Hodgkin‧s lymphoma
1993
Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity in vivo
2000 Standout
How cancer cells evade chemotherapy: sixteenth Richard and Hinda Rosenthal Foundation Award Lecture.
1993
Levels of multidrug resistance (MDR1) P-glycoprotein expression by human breast cancer correlate with in vitro resistance to taxol and doxorubicin.
1998
Positron Emission Tomography Using [18F]-Fluorodeoxy-d -Glucose to Predict the Pathologic Response of Breast Cancer to Primary Chemotherapy
2000
Overexpression of the multidrug resistance gene mdr3 in spontaneous and chemically induced mouse hepatocellular carcinomas.
1990
Monoclonal antibody to an external epitope of the human mdr1 P-glycoprotein.
1993
Nonviral Vectors for Gene Delivery
2008 Standout
Detection of P-glycoprotein isoforms by gene-specific monoclonal antibodies.
1990
Degradable Controlled-Release Polymers and Polymeric Nanoparticles: Mechanisms of Controlling Drug Release
2016 Standout
In vivo detection of multidrug-resistant (MDR1) phenotype by technetium-99m sestamibi scan in untreated breast cancer patients
1997
Regulation of mdr RNA levels in response to cytotoxic drugs in rodent cells.
1990
Functional analysis of chimeric genes obtained by exchanging homologous domains of the mouse mdr1 and mdr2 genes.
1991
Kinase requirements in human cells: III. Altered kinase requirements inVHL−/− cancer cells detected in a pilot synthetic lethal screen
2008 StandoutNobel
Requirement for p53 and p21 to Sustain G 2 Arrest After DNA Damage
1998 StandoutScience
Inhibition of phosphatidylinositide 3-kinase enhances gemcitabine-induced apoptosis in human pancreatic cancer cells.
2000
Loss of p73 gene expression in leukemias/lymphomas due to hypermethylation.
1999
Functions of Ceramide in Coordinating Cellular Responses to Stress
1996 StandoutScience
Endocytosis and the recycling of plasma membrane.
1983 StandoutNobel
Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes [see comments]
1992
Oral administration of lipopolysaccharides activates B-1 cells in the peritoneal cavity and lamina propria of the gut and induces autoimmune symptoms in an autoantibody transgenic mouse.
1994 StandoutNobel
p53 gene mutation in B-cell chronic lymphocytic leukemia is associated with drug resistance and is independent of MDR1/MDR3 gene expression
1993
Structure and expression of the human MDR (P-glycoprotein) gene family.
1989
Quantitative analysis of MDR1 (multidrug resistance) gene expression in human tumors by polymerase chain reaction.
1990
P-glycoprotein expression and function in circulating blood cells from normal volunteers
1994
The Dendritic Cell Receptor for Endocytosis, Dec-205, Can Recycle and Enhance Antigen Presentation via Major Histocompatibility Complex Class II–Positive Lysosomal Compartments
2000 StandoutNobel
Expression of the multidrug resistance-associated protein (MRP) gene in human cancers.
1995
High Levels of a Major Histocompatibility Complex II–Self Peptide Complex on Dendritic Cells from the T Cell Areas of Lymph Nodes
1997 StandoutNobel
Cell cycle deregulation in B-cell lymphomas
2003
A physiologic function for p-glycoprotein (MDR-1) during the migration of dendritic cells from skin via afferent lymphatic vessels
1998 StandoutNobel
Frequent incidence of somatic mutations in translocated BCL2 oncogenes of non-Hodgkin's lymphomas
1992
Itk Negatively Regulates Induction of T Cell Proliferation by CD28 Costimulation
1997 StandoutNobel
Alterations of the Immune System in Ulcerative Colitis and Crohn's Disease
1988
Internalization and degradation of macrophage Fc receptors during receptor-mediated phagocytosis.
1983 StandoutNobel
A phase I trial of doxorubicin, paclitaxel, and valspodar (PSC 833), a modulator of multidrug resistance.
2001
Pharmacogenomics: Translating Functional Genomics into Rational Therapeutics
1999 StandoutScience
Integrating Genetic Approaches into the Discovery of Anticancer Drugs
1997 StandoutScienceNobel
Presentation of a Viral T Cell Epitope Expressed in the CDR3 Region of a Self Immunoglobulin Molecule
1993 StandoutScienceNobel
Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody.
1992
Chitosan Chemistry and Pharmaceutical Perspectives
2004 Standout
Expression and activity of the multidrug resistance P-glycoprotein in human peripheral blood lymphocytes [see comments]
1992
Pathogenesis of Dengue: Challenges to Molecular Biology
1988 StandoutScience
Effects of Breeding Environments on Generation and Activation of Autoreactive B-1 Cells in Anti-red Blood Cell Autoantibody Transgenic Mice
1997 StandoutNobel
Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line
1992 StandoutScience
Works of J Cossman being referenced
Expression of Multidrug Resistance Gene in Human Cancers
1989
Detection of occult follicular lymphoma by specific DNA amplification
1988
Suppression of Immunoglobulin Synthesis by Lymphocyte Subpopulations in Patients With Crohn's Disease
1984
Antigen presentation by Hodgkin's disease cells.
1985
Inactivation of the retinoblastoma gene in human lymphoid neoplasms
1991
Possible role of Fc receptors on cells infected and transformed by herpesvirus: escape from immune cytolysis
1978
Role of the thymus in directing the development of a subset of B lymphocytes.
1982