Citation Impact
Citing Papers
Control of Regulatory T Cell Development by the Transcription Factor Foxp3
2003 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
2005 StandoutScience
Inducible costimulator is required for type 2 antibody isotype switching but not T helper cell type 2 responses in chronic nematode infection
2005 StandoutNobel
Structure of the human TRPM4 ion channel in a lipid nanodisc
2017 StandoutScienceNobel
Selective blockade of inhibitory Fcγ receptor enables human dendritic cell maturation with IL-12p70 production and immunity to antibody-coated tumor cells
2005 StandoutNobel
Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130
2002 StandoutNobel
Functional diversity of helper T lymphocytes
1996 StandoutNature
Crystal structure at 2.2 Å resolution of the pleckstrin homology domain from human dynamin
1994
Cloning and Characterization of the Murine Toll-like Receptor 5 (Tlr5) Gene: Sequence and mRNA Expression Studies in Salmonella-Susceptible MOLF/Ei Mice
2000
WAF1, a potential mediator of p53 tumor suppression
1993 Standout
Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation
1999 StandoutNature
Class Switch Recombination and Somatic Hypermutation in Early Mouse B Cells Are Mediated by B Cell and Toll-like Receptors
2007 StandoutNobel
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
extradenticle, a regulator of homeotic gene activity, is a homolog of the homeobox-containing human proto-oncogene pbx1
1993 StandoutNobel
Inhibition of acute lymphoblastic leukaemia by a Jak-2 inhibitor
1996 Nature
SHIP Modulates Immune Receptor Responses by Regulating Membrane Association of Btk
1998
The PH domain: a common piece in the structural pathcwork of signalling proteins
1993
The immune responses in CD40-deficient mice: Impaired immunoglobulin class switching and germinal center formation
1994
The innate immune response to bacterial flagellin is mediated by Toll-like receptor 5
2001 StandoutNature
Defective B-1 Cell Development and Impaired Immunity against Angiostrongylus cantonensis in IL-5Rα-Deficient Mice
1996
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
1996 StandoutNatureNobel
Inhibition of glycogen synthase kinase-3 by insulin mediated by protein kinase B
1995 StandoutNature
AID Is Required for c-myc/IgH Chromosome Translocations In Vivo
2004 StandoutNobel
Marginal zone B cells exhibit unique activation, proliferative and immunoglobulin secretory responses
1997
The Oncogenic Cysteine-rich LIM domain protein Rbtn2 is essential for erythroid development
1994 StandoutNobel
Cyclins and oncogenesis
1993
Solution structure of a pleckstrin-homology domain
1994 Nature
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Structure of the pleckstrin homology domain from β-spectrin
1994 Nature
A comparative analysis of B cell-mediated myelin oligodendrocyte glycoprotein-experimental autoimmune encephalomyelitis pathogenesis in B cell-deficient mice reveals an effect on demyelination
2002
Chromosomal translocation t(1;19) results in synthesis of a homeobox fusion mRNA that codes for a potential chimeric transcription factor
1990
Chromosomal translocations in human cancer
1994 Nature
The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase
1995 Standout
Structure of the human APO‐1 gene
1994
Crystal structure of the pleckstrin homology domain from dynamin
1994
Identification of a cold receptor reveals a general role for TRP channels in thermosensation
2002 StandoutNatureNobel
Mitogenic Signaling via G Protein-Coupled Receptors
1996 StandoutNobel
In situ class switching and differentiation to IgA-producing cells in the gut lamina propria
2001 StandoutNatureNobel
TRPM2
2014
The spectrum of mutations in Btk that cause X-linked agammaglobulinemia
1995
Segmental expression of Hoxb-1 is controlled by a highly conserved autoregulatory loop dependent upon exd/pbx
1995 StandoutNobel
The Fas Death Factor
1995 StandoutScience
Activation of bruton's tyrosine kinase (BTK) by a point mutation in its pleckstrin homology (PH) domain
1995
The repertoire of human germline vH sequences reveals about fifty groups of VH segments with different hypervariable loops
1992 StandoutNobel
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
Homeodomain-DNA recognition
1994 StandoutNobel
PH domain: the first anniversary
1994
The Primary Immunodeficiencies
1995
Defective B cell development and function in Btk-deficient mice
1995
Are Complex Behaviors Specified by Dedicated Regulatory Genes? Reasoning from Drosophila
2001 StandoutNobel
Suppressor of cytokine signaling 1 negatively regulates Toll-like receptor signaling by mediating Mal degradation
2006
Structure of the high affinity complex of inositol trisphosphate with a phospholipase C pleckstrin homology domain
1995
Pleckstrin homology domains bind to phosphatidylinositol-4,5-bisphosphate
1994 Nature
A new regulatory motif in cell-cycle control causing specific inhibition of cyclin D/CDK4
1993 StandoutNature
Genetic Alterations of Cyclins, Cyclin-Dependent Kinases, and Cdk Inhibitors in Human Cancer
1996
The Tumor Necrosis Factor Ligand and Receptor Families
1996 StandoutNobel
Accumulation of premutagenic DNA lesions in mice defective in removal of oxidative base damage
1999 StandoutNobel
Binding of Bruton's tyrosine kinase to Fyn, Lyn, or Hck through a Src homology 3 domain-mediated interaction.
1994 Nobel
GENETIC DISSECTION OF SEXUAL BEHAVIOR IN DROSOPHILA MELANOGASTER
1997
The pleckstrin homology domain of Bruton tyrosine kinase interacts with protein kinase C.
1994
Genomic organization of IgH gene compared with the expression of Bcl-2 gene in t(14;18)-positive lymphoma
1991 StandoutNobel
Receptor-tyrosine-kinase- and Gβγ-mediated MAP kinase activation by a common signalling pathway
1995 StandoutNatureNobel
Deletion within the Src homology domain 3 of Bruton's tyrosine kinase resulting in X-linked agammaglobulinemia (XLA).
1994
Cancer Cell Cycles
1996 StandoutScience
Targeting G βγ signaling in arterial vascular smooth muscle proliferation: A novel strategy to limit restenosis
1999 StandoutNobel
Binding of beta gamma subunits of heterotrimeric G proteins to the PH domain of Bruton tyrosine kinase.
1994
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Crystal structure of Toll-like receptor adaptor MAL/TIRAP reveals the molecular basis for signal transduction and disease protection
2011 StandoutNobel
Functionally active targeting domain of the beta-adrenergic receptor kinase: an inhibitor of G beta gamma-mediated stimulation of type II adenylyl cyclase.
1994 StandoutNobel
Cellular and molecular characterization of the scurfy mouse mutant.
1999 StandoutNobel
Characterization of a candidate bcl-1 gene.
1991
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
B cell-deficient mice do not develop type II collagen-induced arthritis (CIA)
1998
Src Family Protein Tyrosine Kinases Induce Autoactivation of Bruton's Tyrosine Kinase
1995
ESOP-1, a secreted protein expressed in the hematopoietic, nervous, and reproductive systems of embryonic and adult mice
2000 StandoutNobel
Activation of Tsk and Btk tyrosine kinases by G protein beta gamma subunits.
1995
Immunocyte Ca 2+ Influx System Mediated by LTRPC2
2001 Science
Cellular and Molecular Characterization of the scurfy Mouse Mutant
1999 StandoutNobel
T-Independent Immune Response: New Aspects of B Cell Biology
2000 StandoutScienceNobel
Abnormal B lymphocyte development and autoimmunity in hypoxia-inducible factor 1α-deficient chimeric mice
2002 StandoutNobel
Xid -Like Immunodeficiency in Mice with Disruption of the p85α Subunit of Phosphoinositide 3-Kinase
1999 Science
Cellular Function of Phosphoinositide 3-Kinases: Implications for Development, Immunity, Homeostasis, and Cancer
2001
Solution structure of pleckstrin homology domain of dynamin by heteronuclear NMR spectroscopy.
1995
Genetic control of blood pressure and the angiotensinogen locus.
1995 StandoutNobel
AH/PH Domain-Mediated Interaction between Akt Molecules and Its Potential Role in Akt Regulation
1995
Chromosome Aberrations and Cancer
1991 Science
Activation of BTK by a Phosphorylation Mechanism Initiated by SRC Family Kinases
1996 Science
Current status of cytogenetic research in childhood acute lymphoblastic leukemia
1993
Augmented Expression of a Human Gene for 8-oxoguanine DNA Glycosylase (MutM) in B Lymphocytes of the Dark Zone in Lymph Node Germinal Centers
1997
The chromosomal distribution of mouse odorant receptor genes.
1996 StandoutNobel
A Genetic Linkage Map of the Mouse: Current Applications and Future Prospects
1993 Science
γ3 Gene-Disrupted Mice Selectively Deficient in the Dominant IgG Subclass Made to Bacterial Polysaccharides. II. Increased Susceptibility to Fatal Pneumococcal Sepsis Due to Absence of Anti-Polysaccharide IgG3 Is Corrected by Induction of Anti-Polysaccharide IgG1
2002
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 StandoutScienceNobel
Molecular Basis for Interactions of G Protein βγ Subunits with Effectors
1998 StandoutScienceNobel
Defective Lymphoid Development in Mice Lacking Jak3
1995 StandoutScienceNobel
Regulation of Cell Death Protease Caspase-9 by Phosphorylation
1998 StandoutScience
Works of J. Christopher Grimaldi being referenced
CD38 unresponsiveness of xid B cells implicates Bruton's tyrosine kinase (btk) as a regulator of CD38 induced signal transduction
1995
Signaling through murine CD38 is impaired in antigen receptor‐unresponsive B cells
1995
Murine CD38: an immunoregulatory ectoenzyme
1995
A new approach to the study of haematopoietic development in the yolk sac and embryoid bodies
1995
Lack of detectable somatic hypermutation in the V region of the Ig H chain gene of a human chronic B lymphocytic leukemia.
1988
Mutation of Unique Region of Bruton's Tyrosine Kinase in Immunodeficient XID Mice
1993 Science
An additional breakpoint region in the BCL-1 locus associated with the t(11;14)(q13;q32) translocation of B-lymphocytic malignancy
1989
The t(5;14) chromosomal translocation in a case of acute lymphocytic leukemia joins the interleukin-3 gene to the immunoglobulin heavy chain gene
1989
Genomic structure and chromosomal mapping of the murine CD40 gene.
1992
An additional breakpoint region in the BCL-1 locus associated with the t(11;14)(q13;q32) translocation of B-lymphocytic malignancy
1989
Formation and Hydrolysis of Cyclic ADP-Ribose Catalyzed by Lymphocyte Antigen CD38
1993 Science