Citation Impact
Citing Papers
Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway
2012 StandoutScience
5′-triphosphate RNA requires base-paired structures to activate antiviral signaling via RIG-I
2009
Inhibition of Interferon Signaling by Rabies Virus Phosphoprotein P: Activation-Dependent Binding of STAT1 and STAT2
2006
Hepatitis C virus protease NS3/4A cleaves mitochondrial antiviral signaling protein off the mitochondria to evade innate immunity
2005
Endosomal TLR signaling is required for anti-nucleic acid and rheumatoid factor autoantibodies in lupus
2009 StandoutNobel
Double-Stranded RNA Is Produced by Positive-Strand RNA Viruses and DNA Viruses but Not in Detectable Amounts by Negative-Strand RNA Viruses
2006
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
2016 StandoutNobel
Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125
2007
Disruption of innate immunity due to mitochondrial targeting of a picornaviral protease precursor
2007
The RNA Helicase Lgp2 Inhibits TLR-Independent Sensing of Viral Replication by Retinoic Acid-Inducible Gene-I
2005
Cutting Edge: Roles of Caspase-8 and Caspase-10 in Innate Immune Responses to Double-Stranded RNA
2006
The Regulation of Type I Interferon Production by Paramyxoviruses
2009
Paramyxovirus Disruption of Interferon Signal Transduction: STATus Report
2009
IFN-λ: Novel Antiviral Cytokines
2006
Antiviral innate immunity pathways
2006
Toll-like Receptor-dependent and -independent Viperin Gene Expression and Counter-regulation by PRDI-binding Factor-1/BLIMP1
2006
SEC14L2 enables pan-genotype HCV replication in cell culture
2015 StandoutNatureNobel
AIM2 recognizes cytosolic dsDNA and forms a caspase-1-activating inflammasome with ASC
2009 StandoutNature
Chromatin Modifications and Their Function
2007 Standout
Recognition of RNA virus by RIG-I results in activation of CARD9 and inflammasome signaling for interleukin 1β production
2009
RIG-I-like receptors: their regulation and roles in RNA sensing
2020
Human ADAR1 Prevents Endogenous RNA from Triggering Translational Shutdown
2018 StandoutNobel
Cytoplasmic Listeria monocytogenes stimulates IFN‐β synthesis without requiring the adapter protein MAVS
2006
Evasion of intracellular host defence by hepatitis C virus
2005 Nature
Expression of paramyxovirus V proteins promotes replication and spread of hepatitis C virus in cultures of primary human fetal liver cells
2010 StandoutNobel
Histone H3 and H4 Ubiquitylation by the CUL4-DDB-ROC1 Ubiquitin Ligase Facilitates Cellular Response to DNA Damage
2006
A Toll-like receptor–independent antiviral response induced by double-stranded B-form DNA
2005
Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity
2014 StandoutNobel
Recognition of microorganisms and activation of the immune response
2007 StandoutNature
Intracellular pattern recognition receptors in the host response
2006 Nature
Pattern Recognition Receptors and Inflammation
2010 Standout
The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation
2008
NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice
2012 StandoutNature
CRL4s: the CUL4-RING E3 ubiquitin ligases
2009
Triggering the Innate Antiviral Response through IRF-3 Activation
2007
Recognition of viruses by cytoplasmic sensors
2010
Synthetic Double-Stranded RNAs Are Adjuvants for the Induction of T Helper 1 and Humoral Immune Responses to Human Papillomavirus in Rhesus Macaques
2009 StandoutNobel
Nuclear factor-κB in cancer development and progression
2006 StandoutNature
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
2005 StandoutNature
Intrinsic Immunity Shapes Viral Resistance of Stem Cells
2017 StandoutNobel
The V Proteins of Simian Virus 5 and Other Paramyxoviruses Inhibit Induction of Interferon-β
2002
Select Paramyxoviral V Proteins Inhibit IRF3 Activation by Acting as Alternative Substrates for Inhibitor of κB Kinase ϵ (IKKe)/TBK1
2008
IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction
2005 Standout
Measles virus V protein blocks interferon (IFN)‐α/β but not IFN‐γ signaling by inhibiting STAT1 and STAT2 phosphorylation
2003
Innate immune recognition of viral infection
2006 Standout
Interferons and viruses: an evolutionary arms race of molecular interactions
2015 StandoutNobel
Interferon signalling network in innate defence
2006
Regulation of Antiviral Innate Immune Responses by RIG-I Family of RNA Helicases
2007
Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif
2006
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
The C Proteins of Human Parainfluenza Virus Type 1 Block IFN Signaling by Binding and Retaining Stat1 in Perinuclear Aggregates at the Late Endosome
2012
Genetics and pathogenesis of inflammatory bowel disease
2011 StandoutNature
Nucleic acid‐mediated inflammatory diseases
2008
Ten Strategies of Interferon Evasion by Viruses
2017
PKR Transduces MDA5-Dependent Signals for Type I IFN Induction
2016
Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses
2006 StandoutNature
Optineurin Negatively Regulates the Induction of IFNβ in Response to RNA Virus Infection
2010
Manipulation of the nuclear factor-κB pathway and the innate immune response by viruses
2006
Measles virus V protein blocks Jak1-mediated phosphorylation of STAT1 to escape IFN-α/β signaling
2007
Convergent Evolution of Escape from Hepaciviral Antagonism in Primates
2012
Identification and Characterization of MAVS, a Mitochondrial Antiviral Signaling Protein that Activates NF-κB and IRF3
2005 Standout
Mouse STAT2 Restricts Early Dengue Virus Replication
2010
5,6-Dimethylxanthenone-4-acetic Acid (DMXAA) Activates Stimulator of Interferon Gene (STING)-dependent Innate Immune Pathways and Is Regulated by Mitochondrial Membrane Potential
2012
The Yin and Yang of type I interferon activity in bacterial infection
2005
Processing of Genome 5′ Termini as a Strategy of Negative-Strand RNA Viruses to Avoid RIG-I-Dependent Interferon Induction
2008
NLRP3 inflammasomes are required for atherogenesis and activated by cholesterol crystals
2010 StandoutNature
STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling
2008 StandoutNature
The ubiquitin kinase PINK1 recruits autophagy receptors to induce mitophagy
2015 StandoutNature
Pathogen Recognition and Innate Immunity
2006 Standout
Cytosolic 5′-Triphosphate Ended Viral Leader Transcript of Measles Virus as Activator of the RIG I-Mediated Interferon Response
2007
STING regulates intracellular DNA-mediated, type I interferon-dependent innate immunity
2009 StandoutNature
Recognition of Cytosolic DNA Activates an IRF3-Dependent Innate Immune Response
2006
Inhibition of IFN-α/β signaling by two discrete peptides within measles virus V protein that specifically bind STAT1 and STAT2
2008
Host Innate Immune Receptors and Beyond: Making Sense of Microbial Infections
2008
STAT Protein Interference and Suppression of Cytokine Signal Transduction by Measles Virus V Protein
2003
Characterization of the Amino Acid Residues of Sendai Virus C Protein That Are Critically Involved in Its Interferon Antagonism and RNA Synthesis Down-Regulation
2004
Paramyxovirus V Proteins Interact with the RNA Helicase LGP2 To Inhibit RIG-I-Dependent Interferon Induction
2012
A Shared Interface Mediates Paramyxovirus Interference with Antiviral RNA Helicases MDA5 and LGP2
2009
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
2011 StandoutNobel
Pathogen Recognition and Inflammatory Signaling in Innate Immune Defenses
2009 Standout
Autoantibodies make a U-turn
2005
Shared and Unique Functions of the DExD/H-Box Helicases RIG-I, MDA5, and LGP2 in Antiviral Innate Immunity
2005
Dengue reporter viruses reveal viral dynamics in interferon receptor-deficient mice and sensitivity to interferon effectors in vitro
2012 StandoutNobel
Length-dependent recognition of double-stranded ribonucleic acids by retinoic acid–inducible gene-I and melanoma differentiation–associated gene 5
2008
Ramshackle (Brwd3) promotes light-induced ubiquitylation of Drosophila Cryptochrome by DDB1-CUL4-ROC1 E3 ligase complex
2013 StandoutNobel
Activation of Innate Defense against a Paramyxovirus Is Mediated by RIG-I and TLR7 and TLR8 in a Cell-Type-Specific Manner
2005
Viral evasion and subversion of pattern-recognition receptor signalling
2008
Ultrastructural analysis of hepatitis C virus particles
2013 StandoutNobel
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1β production
2008 StandoutNature
Modeling host interactions with hepatitis B virus using primary and induced pluripotent stem cell-derived hepatocellular systems
2014 StandoutNobel
Characterization of nonprimate hepacivirus and construction of a functional molecular clone
2015 StandoutNobel
Ebola Virus VP35 Protein Binds Double-Stranded RNA and Inhibits Alpha/Beta Interferon Production Induced by RIG-I Signaling
2006
Recognition of viruses by innate immunity
2007
Modeling hepatitis C virus infection using human induced pluripotent stem cells
2012 StandoutNobel
Comparable T helper 1 (Th1) and CD8 T-cell immunity by targeting HIV gag p24 to CD8 dendritic cells within antibodies to Langerin, DEC205, and Clec9A
2011 StandoutNobel
Dissociation of Paramyxovirus Interferon Evasion Activities: Universal and Virus-Specific Requirements for Conserved V Protein Amino Acids in MDA5 Interference
2010
West Nile Virus Evades Activation of Interferon Regulatory Factor 3 through RIG-I-Dependent and -Independent Pathways without Antagonizing Host Defense Signaling
2006
Nipah Virus V and W Proteins Have a Common STAT1-Binding Domain yet Inhibit STAT1 Activation from the Cytoplasmic and Nuclear Compartments, Respectively
2004
The Caenorhabditis elegans ARIP-4 DNA helicase couples mitochondrial surveillance to immune, detoxification, and antiviral pathways
2022 StandoutNobel
Simian Virus 5 V Protein Acts as an Adaptor, Linking DDB1 to STAT2, To Facilitate the Ubiquitination of STAT1
2005
Differential Induction of Type I Interferon Responses in Myeloid Dendritic Cells by Mosquito and Mammalian-Cell-Derived Alphaviruses
2006
RNAi-mediated immunity provides strong protection against the negative-strand RNA vesicular stomatitis virus in Drosophila
2010 StandoutNobel
Inhibition of Retinoic Acid-Inducible Gene I-Mediated Induction of Beta Interferon by the NS1 Protein of Influenza A Virus
2006
STAT3 Ubiquitylation and Degradation by Mumps Virus Suppress Cytokine and Oncogene Signaling
2003
Measles Virus C Protein Interferes with Beta Interferon Transcription in the Nucleus
2011
The Inflammasomes: Guardians of the Body
2009 Standout
Essential role of mda-5 in type I IFN responses to polyriboinosinic:polyribocytidylic acid and encephalomyocarditis picornavirus
2006 StandoutNobel
IFN-α regulates Toll-like receptor-mediated IL-27 gene expression in human macrophages
2007
Dengue Virus Inhibits Alpha Interferon Signaling by Reducing STAT2 Expression
2005
Inhibition of Interferon Regulatory Factor 3 Activation by Paramyxovirus V Protein
2012
Fas-Associated Death Domain-Containing Protein-Mediated Antiviral Innate Immune Signaling Involves the Regulation of Irf7
2007
5'-Triphosphate RNA Is the Ligand for RIG-I
2006 StandoutScience
Inhibition of Toll-Like Receptor 7- and 9-Mediated Alpha/Beta Interferon Production in Human Plasmacytoid Dendritic Cells by Respiratory Syncytial Virus and Measles Virus
2005
STAT2 Is a Primary Target for Measles Virus V Protein-Mediated Alpha/Beta Interferon Signaling Inhibition
2008
Persistent hepatitis C virus infection in microscale primary human hepatocyte cultures
2010 StandoutNobel
TLR3 Is Essential for the Induction of Protective Immunity against Punta Toro Virus Infection by the Double-Stranded RNA (dsRNA), Poly(I:C12U), but not Poly(I:C): Differential Recognition of Synthetic dsRNA Molecules
2007
Nuclear Localization of the Nipah Virus W Protein Allows for Inhibition of both Virus- and Toll-Like Receptor 3-Triggered Signaling Pathways
2005
Nipah Virus Edits Its P Gene at High Frequency To Express the V and W Proteins
2009
The STAT2 Activation Process Is a Crucial Target of Sendai Virus C Protein for the Blockade of Alpha Interferon Signaling
2003
The microbial mimic poly IC induces durable and protective CD4+T cell immunity together with a dendritic cell targeted vaccine
2008 StandoutNobel
The Death Domain Superfamily in Intracellular Signaling of Apoptosis and Inflammation
2007
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
ATP-sensitive potassium channel (K ATP )–dependent regulation of cardiotropic viral infections
2011 StandoutNobel
Works of J. Andrejeva being referenced
Differences in Interferon Sensitivity and Biological Properties of Two Related Isolates of Simian Virus 5: A Model for Virus Persistence
2002
mda-5, but not RIG-I, is a common target for paramyxovirus V proteins
2006
The p127 Subunit (DDB1) of the UV-DNA Damage Repair Binding Protein Is Essential for the Targeted Degradation of STAT1 by the V Protein of the Paramyxovirus Simian Virus 5
2002
Degradation of STAT1 and STAT2 by the V Proteins of Simian Virus 5 and Human Parainfluenza Virus Type 2, Respectively: Consequences for Virus Replication in the Presence of Alpha/Beta and Gamma Interferons
2002
The V proteins of paramyxoviruses bind the IFN-inducible RNA helicase, mda-5, and inhibit its activation of the IFN -β promoter
2004
Mechanism of mda-5 Inhibition by Paramyxovirus V Proteins
2008