Citation Impact
Citing Papers
Distinct Roles of Autophagy in the Heart During Ischemia and Reperfusion
2007
AMP-activated protein kinase (AMPK) action in skeletal muscle via direct phosphorylation of PGC-1α
2007 Standout
Phosphorylation of ULK1 (hATG1) by AMP-Activated Protein Kinase Connects Energy Sensing to Mitophagy
2010 StandoutScience
Mechanisms underlying the resistance to diet-induced obesity in germ-free mice
2007 Standout
AMP-activated protein kinase (AMPK) β1β2 muscle null mice reveal an essential role for AMPK in maintaining mitochondrial content and glucose uptake during exercise
2011
The Kinase LKB1 Mediates Glucose Homeostasis in Liver and Therapeutic Effects of Metformin
2005 StandoutScience
EglN2 associates with the NRF 1‐ PGC 1α complex and controls mitochondrial function in breast cancer
2015 StandoutNobel
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
2011 StandoutNobel
Loss of Hypoxia-Inducible Factor Prolyl Hydroxylase Activity in Cardiomyocytes Phenocopies Ischemic Cardiomyopathy
2010 StandoutNobel
HIF Hydroxylase Pathways in Cardiovascular Physiology and Medicine
2015 StandoutNobel
AMPK regulates energy expenditure by modulating NAD+ metabolism and SIRT1 activity
2009 StandoutNature
Metabolic remodelling of the failing heart: the cardiac burn-out syndrome?
2003
Structural basis for oxygen degradation domain selectivity of the HIF prolyl hydroxylases
2016 StandoutNobel
Control of Cyclin D1 and Breast Tumorigenesis by the EglN2 Prolyl Hydroxylase
2009 StandoutNobel
Causes and Characteristics of Diabetic Cardiomyopathy
2006
The von Hippel–Lindau tumour suppressor protein: O2 sensing and cancer
2008 StandoutNobel
AMP-activated protein kinase: Ancient energy gauge provides clues to modern understanding of metabolism
2005 Standout
Use of Cells Expressing γ Subunit Variants to Identify Diverse Mechanisms of AMPK Activation
2010
Roles of individual prolyl‐4‐hydroxylase isoforms in the first 24 hours following transient focal cerebral ischaemia: insights from genetically modified mice
2012 StandoutNobel
The Failing Heart — An Engine Out of Fuel
2007 Standout
Abnormal myocardial insulin signalling in type 2 diabetes and left-ventricular dysfunction
2009
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
AMP‐activated protein kinase and cancer
2009
Energy metabolism in heart failure
2003
Cardiac hypertrophy is enhanced in PPAR -/- mice in response to chronic pressure overload
2008
AMPK: An Emerging Drug Target for Diabetes and the Metabolic Syndrome
2009
Phosphoenolpyruvate Is a Metabolic Checkpoint of Anti-tumor T Cell Responses
2015
AMP-activated protein kinase mediates ischemic glucose uptake and prevents postischemic cardiac dysfunction, apoptosis, and injury
2004
Insulin resistance, abnormal energy metabolism and increased ischemic damage in the chronically infarcted rat heart
2006
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
The NOX Family of ROS-Generating NADPH Oxidases: Physiology and Pathophysiology
2007 Standout
Activation of AMP-activated Protein Kinase Induces p53-dependent Apoptotic Cell Death in Response to Energetic Stress
2007
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Transgenesis and cardiac energetics: new insights into cardiac metabolism
2004
Obesity and Cardiovascular Disease: A Scientific Statement From the American Heart Association
2021 Standout
Regulation of cancer cell metabolism
2011 Standout
Endoplasmic Reticulum Stress and the Inflammatory Basis of Metabolic Disease
2010 Standout
Disruption of Fnip1 Reveals a Metabolic Checkpoint Controlling B Lymphocyte Development
2012 StandoutNobel
Autophagy in the Pathogenesis of Disease
2008 Standout
Crucial role for LKB1 to AMPKα2 axis in the regulation of CD36-mediated long-chain fatty acid uptake into cardiomyocytes☆
2008
Myocardial Substrate Metabolism in the Normal and Failing Heart
2005 Standout
Hearts from Mice Fed a Non-Obesogenic High-Fat Diet Exhibit Changes in Their Oxidative State, Calcium and Mitochondria in Parallel with Increased Susceptibility to Reperfusion Injury
2014
Autophagy in Human Health and Disease
2013 Standout
Myc controls transcriptional regulation of cardiac metabolism and mitochondrial biogenesis in response to pathological stress in mice
2010
Diabetes Mellitus and Heart Failure
2017
Methods in Mammalian Autophagy Research
2010 Standout
New Molecular Insights of Insulin in Diabetic Cardiomyopathy
2016
Understanding the Intersections between Metabolism and Cancer Biology
2017 Standout
AMP-activated/SNF1 protein kinases: conserved guardians of cellular energy
2007 Standout
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Apolipoprotein B Production Reduces Lipotoxic Cardiomyopathy
2004
AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1
2011 Standout
The Hallmarks of Aging
2013 Standout
TSC2 Integrates Wnt and Energy Signals via a Coordinated Phosphorylation by AMPK and GSK3 to Regulate Cell Growth
2006 Standout
Role of the nitric oxide pathway in AMPK-mediated glucose uptake and GLUT4 translocation in heart muscle
2004
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
EGLN1 Inhibition and Rerouting of α-Ketoglutarate Suffice for Remote Ischemic Protection
2016 StandoutNobel
AMPK: a nutrient and energy sensor that maintains energy homeostasis
2012 Standout
Biochemical and biophysical aspects of collagen nanostructure in the extracellular matrix
2007
Autochthonous tumors driven by Rb1 loss have an ongoing requirement for the RBP2 histone demethylase
2018 StandoutNobel
Diabetic Cardiomyopathy: Does the Type of Diabetes Matter?
2016
AMP-Activated Protein Kinase in the Heart
2007
Effect of bariatric surgery on heart failure
2017
Transverse aortic constriction leads to accelerated heart failure in mice lacking PPAR-γ coactivator 1α
2006
AMP-activated protein kinase and the metabolic syndrome
2005
Diabetic Cardiomyopathy
2018 Standout
Improvement of Cardiac Functions by Chronic Metformin Treatment Is Associated With Enhanced Cardiac Autophagy in Diabetic OVE26 Mice
2011
A Feedback Loop Involving the Phd3 Prolyl Hydroxylase Tunes the Mammalian Hypoxic Response In Vivo
2009 StandoutNobel
Pressure Overload–Induced Myocardial Hypertrophy in Mice Does Not Require gp91 phox
2004
Mechanisms for Increased Glycolysis in the Hypertrophied Rat Heart
2004
Maintaining Ancient Organelles
2015
Reactivation of Hepatic EPO Synthesis in Mice After PHD Loss
2010 StandoutScienceNobel
Somatic inactivation of the PHD2 prolyl hydroxylase causes polycythemia and congestive heart failure
2007 StandoutNobel
Regulation of ventilatory sensitivity and carotid body proliferation in hypoxia by the PHD2/HIF‐2 pathway
2015 StandoutNobel
Lethal mitochondrial cardiomyopathy in a hypomorphic Med30 mouse mutant is ameliorated by ketogenic diet
2011 StandoutNobel
Mineralocorticoid Receptor Inhibition Ameliorates the Transition to Myocardial Failure and Decreases Oxidative Stress and Inflammation in Mice With Chronic Pressure Overload
2005
On the pivotal role of PPARa in adaptation of the heart to hypoxia and why fat in the diet increases hypoxic injury
2016 StandoutNobel
AMPK: A Key Sensor of Fuel and Energy Status in Skeletal Muscle
2006
Relating tissue/organ energy expenditure to metabolic fluxes in mouse and human: experimental data integrated with mathematical modeling
2014
Inhibition of the oxygen sensor PHD2 in the liver improves survival in lactic acidosis by activating the Cori cycle
2015 StandoutNobel
Is the Failing Heart Energy Starved?
2004
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Treatment of erythropoietin deficiency in mice with systemically administered siRNA
2012 StandoutNobel
Works of Ivan Luptak being referenced
Long-Term Effects of Increased Glucose Entry on Mouse Hearts During Normal Aging and Ischemic Stress
2007
Aberrant activation of AMP-activated protein kinase remodels metabolic network in favor of cardiac glycogen storage
2007
Glucose Metabolism and Energy Homeostasis in Mouse Hearts Overexpressing Dominant Negative α2 Subunit of AMP-activated Protein Kinase
2003
Genetic loss of insulin receptors worsens cardiac efficiency in diabetes
2012
Effects of Direct Renin Inhibition on Myocardial Fibrosis and Cardiac Fibroblast Function
2013
Effects of chronic Akt activation on glucose uptake in the heart
2005
Protein remodeling of the heart ventricles in hereditary hypertriglyceridemic rat: effect of ace-inhibition
2005
Mitochondrial Reactive Oxygen Species Mediate Cardiac Structural, Functional, and Mitochondrial Consequences of Diet‐Induced Metabolic Heart Disease
2016
Cardiac-Specific Overexpression of GLUT1 Prevents the Development of Heart Failure Attributable to Pressure Overload in Mice
2002
Decreased Contractile and Metabolic Reserve in Peroxisome Proliferator–Activated Receptor-α–Null Hearts Can Be Rescued by Increasing Glucose Transport and Utilization
2005
Mitofusin-2 Maintains Mitochondrial Structure and Contributes to Stress-Induced Permeability Transition in Cardiac Myocytes
2011
Hydrogen Peroxide–Mediated SERCA Cysteine 674 Oxidation Contributes to Impaired Cardiac Myocyte Relaxation in Senescent Mouse Heart
2013