Citation Impact
Citing Papers
Monofunctional Platinum–DNA Adducts Are Strong Inhibitors of Transcription and Substrates for Nucleotide Excision Repair in Live Mammalian Cells
2011
MET Amplification Leads to Gefitinib Resistance in Lung Cancer by Activating ERBB3 Signaling
2007 StandoutScience
The mucin-selective protease StcE enables molecular and functional analysis of human cancer-associated mucins
2019 StandoutNobel
X-linked cholestasis in mouse due to mutations of the P4-ATPase ATP11C
2011 StandoutNobel
An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins
2020 StandoutNobel
Marked Genomic Differences Characterize Primary and Secondary Glioblastoma Subtypes and Identify Two Distinct Molecular and Clinical Secondary Glioblastoma Entities
2006
Regulation of phosphoinositide 3-kinase expression in health and disease
2009
Moderated estimation of fold change and dispersion for RNA-seq data with DESeq2
2014 Standout
Detection of Clonal and Subclonal Copy-Number Variants in Cell-Free DNA from Patients with Breast Cancer Using a Massively Multiplexed PCR Methodology
2015
Comprehensive molecular portraits of human breast tumours
2012 StandoutNature
The functional loss of the retinoblastoma tumour suppressor is a common event in basal-like and luminal B breast carcinomas
2008
Germline BRCA1 Mutations and a Basal Epithelial Phenotype in Breast Cancer
2003
Comprehensive genomic characterization defines human glioblastoma genes and core pathways
2008 StandoutNature
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
The lncRNA MIR31HG regulates p16INK4A expression to modulate senescence
2015
An integrated encyclopedia of DNA elements in the human genome
2012 StandoutNature
Computational identification of hepatitis C virus associated microRNA-mRNA regulatory modules in human livers
2009
Gene expression profiling predicts clinical outcome of breast cancer
2002 StandoutNature
The DNA-damage response in human biology and disease
2009 StandoutNature
IDH1andIDH2Mutations in Gliomas
2009 Standout
Circular RNAs are a large class of animal RNAs with regulatory potency
2013 StandoutNature
The rise of regulatory RNA
2014
Treatment triumphs
2014 StandoutNatureNobel
Changes in the Expression of Nephrin Gene and Protein in Experimental Diabetic Nephropathy
2001
Lineage-Specific Gene Duplication and Loss in Human and Great Ape Evolution
2004
9p21 DNA variants associated with coronary artery disease impair interferon-γ signalling response
2011 Nature
P53-regulated long non-coding RNA TUG1 affects cell proliferation in human non-small cell lung cancer, partly through epigenetically regulating HOXB7 expression
2014
Genomic Alterations in Liquid Biopsies from Patients with Bladder Cancer
2016
A genome-wide comparison of recent chimpanzee and human segmental duplications
2005 StandoutNatureNobel
Genetic instabilities in human cancers
1998 StandoutNature
A new mathematical model for relative quantification in real-time RT-PCR
2001 Standout
Long Noncoding RNAs in Cancer Pathways
2016 Standout
Smad-dependent and Smad-independent pathways in TGF-β family signalling
2003 StandoutNature
Allelic loss at 1p and 19q frequently occurs in association and may represent early oncogenic events in oligodendroglial tumors
1995
Epidermal growth factor receptor: mechanisms of activation and signalling
2003
ERβ Impedes Prostate Cancer EMT by Destabilizing HIF-1α and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading
2010
Cryo-EM structure of the protein-conducting ERAD channel Hrd1 in complex with Hrd3
2017 StandoutNatureNobel
Detection of ubiquitous and heterogeneous mutations in cell-free DNA from patients with early-stage non-small-cell lung cancer
2016
Analyzing real-time PCR data by the comparative CT method
2008 Standout
TAM Receptors Are Pleiotropic Inhibitors of the Innate Immune Response
2007
BRAFV600E remodels the melanocyte transcriptome and induces BANCR to regulate melanoma cell migration
2012
Significance, detection and markers of disseminated breast cancer cells
2006
The Two-Handed E Box Binding Zinc Finger Protein SIP1 Downregulates E-Cadherin and Induces Invasion
2001
Expression of Linear and Novel Circular Forms of an INK4/ARF-Associated Non-Coding RNA Correlates with Atherosclerosis Risk
2010
Long Noncoding RNAs in Cancer: From Function to Translation
2015
High resolution analysis of DNA copy number variation using comparative genomic hybridization to microarrays
1998 Standout
How stem cells age and why this makes us grow old
2007
Large non-coding RNAs: missing links in cancer?
2010
Integrated genomic characterization of endometrial carcinoma
2013 StandoutNature
Liquid biopsies come of age: towards implementation of circulating tumour DNA
2017 Standout
Differentiation of mammary tumors and reduction in metastasis upon Malat1 lncRNA loss
2015
Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes
2002 Standout
Junk DNA and the long non-coding RNA twist in cancer genetics
2015
Transactivation of miR-34a by p53 Broadly Influences Gene Expression and Promotes Apoptosis
2007 Standout
Standardization and quality control studies of ‘real-time’ quantitative reverse transcriptase polymerase chain reaction of fusion gene transcripts for residual disease detection in leukemia – A Europe Against Cancer Program
2003
A diverse range of gene products are effectors of the type I interferon antiviral response
2011 StandoutNatureNobel
Origin and physiological roles of inflammation
2008 StandoutNature
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
The Shortest Telomere, Not Average Telomere Length, Is Critical for Cell Viability and Chromosome Stability
2001 StandoutNobel
DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis
2020 StandoutNatureNobel
Interplay of p53 and DNA-repair protein XRCC4 in tumorigenesis, genomic stability and development
2000 Nature
MUC1-C oncoprotein as a target in breast cancer: activation of signaling pathways and therapeutic approaches
2012
The Hallmarks of Aging
2013 Standout
CHD5 Is a Tumor Suppressor at Human 1p36
2007
Transcriptome sequencing across a prostate cancer cohort identifies PCAT-1, an unannotated lincRNA implicated in disease progression
2011
Multicolour spectral karyotyping of mouse chromosomes
1996
Genome-scale analysis of aberrant DNA methylation in colorectal cancer
2011
Effect of experimental treatment on housekeeping gene expression: validation by real-time, quantitative RT-PCR
2000
Hepatic Stellate Cells Secrete Angiopoietin 1 That Induces Angiogenesis in Liver Fibrosis
2008
Cancer vaccines and carbohydrate epitopes
2011
Alternatively Spliced Nephrin in Experimental Glomerular Disease of the Rat
2000
DNA Ligase IV Deficiency in Mice Leads to Defective Neurogenesis and Embryonic Lethality via the p53 Pathway
2000
Hepatic Stellate Cells: Protean, Multifunctional, and Enigmatic Cells of the Liver
2008 Standout
25 years of interferon-based treatment of chronic hepatitis C: an epoch coming to an end
2013
Genetic Alterations of Cyclins, Cyclin-Dependent Kinases, and Cdk Inhibitors in Human Cancer
1996
Activating Mutations in the Epidermal Growth Factor Receptor Underlying Responsiveness of Non–Small-Cell Lung Cancer to Gefitinib
2004 Standout
Analysis of Relative Gene Expression Data Using Real-Time Quantitative PCR and the 2−ΔΔCT Method
2001 Standout
Robustly detecting differential expression in RNA sequencing data using observation weights
2014
Hepatitis C Virus RNA Functionally Sequesters miR-122
2015 StandoutNobel
Absolute quantification of mRNA using real-time reverse transcription polymerase chain reaction assays
2000 Standout
Phenanthriplatin, a monofunctional DNA-binding platinum anticancer drug candidate with unusual potency and cellular activity profile
2012
Protease-activated receptor 1 (PAR1) signalling desensitization is counteracted via PAR4 signalling in human platelets
2011 StandoutNobel
Novel interferon-β-induced gene expression in peripheral blood cells
2007
The Next Generation of Platinum Drugs: Targeted Pt(II) Agents, Nanoparticle Delivery, and Pt(IV) Prodrugs
2016 Standout
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
Monofunctional and Higher-Valent Platinum Anticancer Agents
2013
Inhibition of the Met Receptor in Mesothelioma
2005
A niche that triggers aggressiveness within BRCA1-IRIS overexpressing triple negative tumors is supported by reciprocal interactions with the microenvironment
2017
A potent transrepression domain in the retinoblastoma protein induces a cell cycle arrest when bound to E2F sites.
1995 StandoutNobel
Third row transition metals for the treatment of cancer
2015
Diabetic nephropathy is markedly enhanced in mice lacking the bradykinin B2 receptor
2004 StandoutNobel
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Cancer Cell Cycles
1996 StandoutScience
The MIQE Guidelines: Minimum Information for Publication of Quantitative Real-Time PCR Experiments
2009 Standout
Hypoxia-inducible factors regulate pluripotency factor expression by ZNF217- and ALKBH5-mediated modulation of RNA methylation in breast cancer cells
2016 StandoutNobel
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
The hereditary renal cell carcinoma 3;8 translocation fuses FHIT to a patched- related gene, TRC8
1998
A Monofunctional Platinum Complex Coordinated to a Rhodium Metalloinsertor Selectively Binds Mismatched DNA in the Minor Groove
2015
Why the kidney glomerulus does not clog: A gel permeation/diffusion hypothesis of renal function
2003 StandoutNobel
Molecular genetic analysis of oligodendroglial tumors shows preferential allelic deletions on 19q and 1p.
1994
Cancer Genome Landscapes
2013 StandoutScience
Clathrin-mediated Endocytosis of MUC1 Is Modulated by Its Glycosylation State
2000
Galectins: Multitask signaling molecules linking fibroblast, endothelial and immune cell programs in the tumor microenvironment
2018
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Allelotyping of ductal carcinoma in situ of the breast: deletion of loci on 8p, 13q, 16q, 17p and 17q.
1995
Understanding and improving platinum anticancer drugs--phenanthriplatin.
2014
Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation
2009 StandoutScience
Growth suppression by p18, a p16INK4/MTS1- and p14INK4B/MTS2-related CDK6 inhibitor, correlates with wild-type pRb function.
1994
The Chiral Potential of Phenanthriplatin and Its Influence on Guanine Binding
2014
The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease
2006 StandoutScience
Works of Ivan Bièche being referenced
ZNF217 Is a Marker of Poor Prognosis in Breast Cancer That Drives Epithelial–Mesenchymal Transition and Invasion
2012
A Six-Gene Signature Predicting Breast Cancer Lung Metastasis
2008
Molecular Profiling of Inflammatory Breast Cancer
2004
Characterization of a Germ-Line Deletion, Including the Entire INK4/ARF Locus, in a Melanoma-Neural System Tumor Family: Identification of ANRIL , an Antisense Noncoding RNA Whose Expression Coclusters with ARF
2007
Loss of heterozygosity at 13q14 correlates with RB1 gene underexpression in human breast cancer.
2000
Anaplastic oligodendrogliomas with 1p19q codeletion have a proneural gene expression profile
2008
Two distinct amplified regions at 17q11-q21 involved in human primary breast cancer.
1996
Prognostic value of maspin mRNA expression in ERα-positive postmenopausal breast carcinomas
2003
CD133, CD15/SSEA-1, CD34 or side populations do not resume tumor-initiating properties of long-term cultured cancer stem cells from human malignant glio-neuronal tumors
2010
Liver Gene Expression Signature of Mild Fibrosis in Patients With Chronic Hepatitis C
2005
Novel approach to quantitative polymerase chain reaction using real-time detection: Application to the detection of gene amplification in breast cancer
1998
A quantitative gene expression study suggests a role for angiopoietins in focal nodular hyperplasia
2003
Elevated growth-arrest-specific protein 6 plasma levels in patients with severe sepsis
2005
Brief communications oncogene amplification per se: An independent prognostic factor in human breast cancer
1994
Liver gene expression signature to predict response to pegylated interferon plus ribavirin combination therapy in patients with chronic hepatitis C
2007
Inter-laboratory quality control for hormone-dependent gene expression in human breast tumors using real-time reverse transcription-polymerase chain reaction
2004
Epigenetic inactivation of SLIT3 and SLIT1 genes in human cancers
2004
Molecular profiling of early stage liver fibrosis in patients with chronic hepatitis C virus infection
2004
MUC1 Mucin Gene, Transcripts, and Protein in Adenomas and Papillary Carcinomas of the Thyroid
1997
VEGF overexpression in clinically localized prostate tumors and neuropilin-1 overexpression in metastatic forms
2000
A gene dosage effect is responsible for high overexpression of the MUC1 gene observed in human breast tumors
1997
Genetic alterations in breast cancer
1995
Molecular analysis of the FHIT gene in human prostate cancer
1998
Loss of heterozygosity on chromosome 7q and aggressive primary breast cancer
1992
11q13 Amplification in local recurrence of human primary breast cancer
1995
OTX008, a selective small-molecule inhibitor of galectin-1, downregulates cancer cell proliferation, invasion and tumour angiogenesis
2014
Quantification of TEL–AML1 transcript for minimal residual disease assessment in childhood acute lymphoblastic leukaemia
2001
CXC chemokines located in the 4q21 region are up-regulated in breast cancer
2007
Genetics, Genomics, and Proteomics: Implications for the Diagnosis and the Treatment of Chronic Hepatitis C
2007
Role of Noncoding RNA ANRIL in Genesis of Plexiform Neurofibromas in Neurofibromatosis Type 1
2011
Circulating tumor DNA as a non‐invasive substitute to metastasis biopsy for tumor genotyping and personalized medicine in a prospective trial across all tumor types
2014
A tumor suppressor gene on chromosome 1p32-pter controls the amplification of MYC family genes in breast cancer.
1994
Major improvement in the efficacy of BRCA1 mutation screening using morphoclinical features of breast cancer.
2000
An intronic polymorphism in the PAR-1 gene is associated with platelet receptor density and the response to SFLLRN
2003
Two distinct regions involved in 1p deletion in human primary breast cancer.
1993
ANTICANCER ACTIVITY OF PYRIPLATIN, A MONOFUNCTIONAL CATIONIC PLATINUM(II) COMPOUND, IN HUMAN CANCER CELLS
2011
Association Analysis Indicates That a Variant GATA-Binding Site in the PIK3CB Promoter Is a Cis-Acting Expression Quantitative Trait Locus for This Gene and Attenuates Insulin Resistance in Obese Children
2007
Expression analysis of estrogen receptor alpha coregulators in breast carcinoma: evidence that NCOR1 expression is predictive of the response to tamoxifen.
2003
IL-1β produced by aggressive breast cancer cells is one of the factors that dictate their interactions with mesenchymal stem cells through chemokine production
2015
TaqMan PCR-based Gene Dosage Assay for Predictive Testing in Individuals from a Cancer Family with INK4 Locus Haploinsufficiency
1999
The HOXB7 protein renders breast cancer cells resistant to tamoxifen through activation of the EGFR pathway
2011
(C-A)n microsatellite repeat D7S522 is the most commonly deleted region in human primary breast cancer.
1994
Real-Time Reverse Transcription-PCR Assay for Future Management of ERBB2-based Clinical Applications
1999
Alteration of Met protooncogene product expression and prognosis in breast carcinomas.
1999
Gene expression and hepatitis C virus infection
2008
ANRIL , a long, noncoding RNA, is an unexpected major hotspot in GWAS
2010
Quantitation of MYC gene expression in sporadic breast tumors with a real-time reverse transcription-PCR assay.
1999