Standout Papers

Epidermal Growth Factor (EGF)-induced Generation of Hydrogen Peroxide 1997 2026 2006 2016 1.0k
  1. Epidermal Growth Factor (EGF)-induced Generation of Hydrogen Peroxide (1997)
    Yun Soo Bae, Sang Won Kang et al. Journal of Biological Chemistry

Citation Impact

Citing Papers

Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signaling
2010
A monomeric G protein-coupled receptor isolated in a high-density lipoprotein particle efficiently activates its G protein
2007 StandoutNobel
In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter
2010 StandoutNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Lysine Acetylation Targets Protein Complexes and Co-Regulates Major Cellular Functions
2009 StandoutScience
Strategy for Dual-Analyte Luciferin Imaging: In Vivo Bioluminescence Detection of Hydrogen Peroxide and Caspase Activity in a Murine Model of Acute Inflammation
2013 StandoutNobel
Inhibition of lactate dehydrogenase A induces oxidative stress and inhibits tumor progression
2010 StandoutNobel
Protein Kinase B Activation by Reactive Oxygen Species Is Independent of Tyrosine Kinase Receptor Phosphorylation and Requires Src Activity
2003
Hallmarks of Cancer: The Next Generation
2011 Standout
Hydrogen peroxide sensing, signaling and regulation of transcription factors
2014
Cancer Cell Metabolism
2011
The DNA-damage response in human biology and disease
2009 StandoutNature
Cell mechanics and the cytoskeleton
2010 StandoutNature
Peroxide-dependent sulfenylation of the EGFR catalytic site enhances kinase activity
2011
Structure of the TRPA1 ion channel suggests regulatory mechanisms
2015 StandoutNatureNobel
Positive feedback interactions between microtubule and actin dynamics during cell motility
1999
Distinct Roles of Thioredoxin in the Cytoplasm and in the Nucleus
1999
Oxyl radicals, redox-sensitive signalling cascades and antioxidants
2007 Standout
Ferroptosis as a p53-mediated activity during tumour suppression
2015 StandoutNature
Roles of Superoxide Radical Anion in Signal Transduction Mediated by Reversible Regulation of Protein-tyrosine Phosphatase 1B
1999
Thiol chemistry and specificity in redox signaling
2008
Oxygen radicals and signaling
1998
Free radicals, metals and antioxidants in oxidative stress-induced cancer
2006 Standout
Reversible Inactivation of the Tumor Suppressor PTEN by H2O2
2002
Oncogenic kinase signalling
2001 StandoutNature
Fluorescent probes for nitric oxide and hydrogen peroxide in cell signaling
2007
Oxidative stress and gene regulation
2000
Relating biochemistry and function in the myosin superfamily
2003
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Phospholipid Hydroperoxides Are Substrates for Non-selenium Glutathione Peroxidase
1999
Molecular imaging of hydrogen peroxide produced for cell signaling
2007
Redox regulation of PI 3-kinase signalling via inactivation of PTEN
2003
Genome-scale transcriptional activation by an engineered CRISPR-Cas9 complex
2014 StandoutNature
Ras Proteins Induce Senescence by Altering the Intracellular Levels of Reactive Oxygen Species
1999
Reversible Inactivation of Protein-tyrosine Phosphatase 1B in A431 Cells Stimulated with Epidermal Growth Factor
1998
Platelet-derived Growth Factor-induced H2O2 Production Requires the Activation of Phosphatidylinositol 3-Kinase
2000
REDD1, a Developmentally Regulated Transcriptional Target of p63 and p53, Links p63 to Regulation of Reactive Oxygen Species
2002
Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatases
2001
Novel homologs of gp91phox
2000
Nerve Growth Factor-induced Neuronal Differentiation Requires Generation of Rac1-regulated Reactive Oxygen Species
2000
Mice with Targeted Mutation of Peroxiredoxin 6 Develop Normally but Are Susceptible to Oxidative Stress
2003
Insulin Signaling Is Inhibited by Micromolar Concentrations of H2O2
1999
Essential role for the peroxiredoxin Prdx1 in erythrocyte antioxidant defence and tumour suppression
2003 Nature
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
ROS Function in Redox Signaling and Oxidative Stress
2014 Standout
Antioxidant enzymes and human diseases
1999 Standout
Redox regulation of protein tyrosine phosphatase 1B involves a sulphenyl-amide intermediate
2003 Nature
Myosin IIB Is Unconventionally Conventional
2003
Role of Oxidative Modifications in Atherosclerosis
2004 Standout
Oxidative stress-inducible proteins in macrophages
1999
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Regulation of cancer cell metabolism
2011 Standout
The Inactivation Mechanism of Low Molecular Weight Phosphotyrosine-protein Phosphatase by H2O2
1998
Tyrosine Phosphorylation Regulates H2O2Production in Lung Fibroblasts Stimulated by Transforming Growth Factor β1
1998
Actin-Based Cell Motility and Cell Locomotion
1996 Standout
Cell transformation by the superoxide-generating oxidase Mox1
1999 Nature
Regulation of protein function by S‐glutathiolation in response to oxidative and nitrosative stress
2000
Salmonella typhi uses CFTR to enter intestinal epithelial cells
1998 StandoutNatureNobel
Reactive Oxygen Species and Antioxidants in Signal Transduction and Gene Expression
2009
Oncogenic Mutations Counteract Intrinsic Disorder in the EGFR Kinase and Promote Receptor Dimerization
2012 StandoutNobel
Identification of Proteins Containing Cysteine Residues That Are Sensitive to Oxidation by Hydrogen Peroxide at Neutral pH
2000
Disease-associated Mutations and Alternative Splicing Alter the Enzymatic and Motile Activity of Nonmuscle Myosins II-B and II-C
2005
Cloning and Characterization of a Lysosomal Phospholipase A2, 1-O-Acylceramide Synthase
2002
Beyond LDL oxidation: ROS in vascular signal transduction
2003
Peroxiredoxin Functions as a Peroxidase and a Regulator and Sensor of Local Peroxides
2011
Role of sulfiredoxin as a regulator of peroxiredoxin function and regulation of its expression
2012
Regulation of Phosphoinositide-specific Phospholipase C Isozymes
1997
A Nuclear-Localized Fluorescent Hydrogen Peroxide Probe for Monitoring Sirtuin-Mediated Oxidative Stress Responses In Vivo
2011
Oxidants, oxidative stress and the biology of ageing
2000 StandoutNature
Epidermal growth factor receptors: critical mediators of multiple receptor pathways
1999
Histone deacetylase inhibitors: molecular mechanisms of action
2007
Imaging Dynamic Redox Changes in Mammalian Cells with Green Fluorescent Protein Indicators
2004 StandoutNobel
Calcium-independent phospholipase A2: structure and function
2000
Reactive oxygen species have a causal role in multiple forms of insulin resistance
2006 StandoutNature
Redox Regulation of Cellular Signalling
1999
Reactive Oxygen Species- and Dimerization-induced Activation of Apoptosis Signal-regulating Kinase 1 in Tumor Necrosis Factor-α Signal Transduction
1998
Regulation of PDGF signalling and vascular remodelling by peroxiredoxin II
2005 Nature
Advances in our understanding of peroxiredoxin, a multifunctional, mammalian redox protein
2002
Human p21-activated kinase (Pak1) regulates actin organization in mammalian cells
1997
Quantitative reactivity profiling predicts functional cysteines in proteomes
2010 StandoutNatureNobel
Emerging roles of thioredoxin cycle enzymes in the central nervous system
2005
Reversible Oxidation and Inactivation of Protein Tyrosine Phosphatases In Vivo
2002
CED-1 Is a Transmembrane Receptor that Mediates Cell Corpse Engulfment in C. elegans
2001 StandoutNobel
Identification of a 120 kd hair-bundle myosin located near stereociliary tips
1993
The expanding superfamily of phospholipase A2 enzymes: classification and characterization
2000 Standout
ZAP-70-dependent and -independent Activation of Erk in Jurkat T Cells
1998
Unconventional myosins
1992
Cellular mechanisms and physiological consequences of redox-dependent signalling
2014 Standout
Signalization and cytoskeleton activity through myosin IB during the early steps of phagocytosis in Entamoeba histolytica: a proteomic approach
2005
Reactivity of biologically important thiol compounds with superoxide and hydrogen peroxide
1999
CLIP170-like tip1p Spatially Organizes Microtubular Dynamics in Fission Yeast
2000 StandoutNobel
Reactive Oxygen Species as Downstream Mediators of Angiogenic Signaling by Vascular Endothelial Growth Factor Receptor-2/KDR
2002
Protein kinase C signaling and oxidative stress
2000
1-Cysteine peroxiredoxin: A dual-function enzyme with peroxidase and acidic Ca2+-independent phospholipase A2 activities
2010
Cellular Regulation by Hydrogen Peroxide
2003
Matrix Elasticity Directs Stem Cell Lineage Specification
2006 Standout
Isoforms of mammalian peroxiredoxin that reduce peroxides in presence of thioredoxin
1999
Inactivation of Human Peroxiredoxin I during Catalysis as the Result of the Oxidation of the Catalytic Site Cysteine to Cysteine-sulfinic Acid
2002
Cell Signaling by Receptor Tyrosine Kinases
2000 Standout
Inactivation of Peroxiredoxin I by Phosphorylation Allows Localized H2O2 Accumulation for Cell Signaling
2010
Functions and Mechanisms of Redox Regulation of Cysteine-Based Phosphatases
2005
Controlled Elimination of Intracellular H 2 O2: Regulation of Peroxiredoxin, Catalase, and Glutathione Peroxidase via Post-translational Modification
2005
Electrostatic origin of the unidirectionality of walking myosin V motors
2013 StandoutNobel
Reactive oxygen species in tumor progression
2005
Molecular mechanisms of nonmuscle myosin-II regulation
1999
A Palette of Fluorescent Probes with Varying Emission Colors for Imaging Hydrogen Peroxide Signaling in Living Cells
2010
Signaling pathways in phagocytosis
1999
First in Class, Potent, and Orally Bioavailable NADPH Oxidase Isoform 4 (Nox4) Inhibitors for the Treatment of Idiopathic Pulmonary Fibrosis
2010
Myosin IIB Is Required for Growth Cone Motility
2001
Myosin is involved in postmitotic cell spreading.
1995
Tissue distribution and subcellular localization of mammalian myosin I.
1992
Identification, characterization and cloning of myr 1, a mammalian myosin-I.
1993
Hydrogen peroxide mediates the cell growth and transformation caused by the mitogenic oxidase Nox1
2001
Prolonged Production of Reactive Oxygen Species in Response to B Cell Receptor Stimulation Promotes B Cell Activation and Proliferation
2012
The Major Target of the Endogenously Generated Reactive Oxygen Species in Response to Insulin Stimulation Is Phosphatase and Tensin Homolog and Not Phosphoinositide-3 Kinase (PI-3 Kinase) in the PI-3 Kinase/Akt Pathway
2004
H2O2-dependent Activation of GCLC-ARE4 Reporter Occurs by Mitogen-activated Protein Kinase Pathways without Oxidation of Cellular Glutathione or Thioredoxin-1
2004
Redox Regulation of Epidermal Growth Factor Receptor Signaling through Cysteine Oxidation
2012
Prx1 Suppresses Radiation-Induced c-Jun NH2-Terminal Kinase Signaling in Lung Cancer Cells through Interaction with the Glutathione S-Transferase Pi/c-Jun NH2-Terminal Kinase Complex
2006
Thioredoxin
2003
Actin-dependent motile forces and cell motility
1994
Reversing the Inactivation of Peroxiredoxins Caused by Cysteine Sulfinic Acid Formation
2003 Science
Energy Substrate Modulates Mitochondrial Structure and Oxidative Capacity in Cancer Cells
2004
Reactive oxygen species in cell signaling
2000 Standout
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
Tissue Cells Feel and Respond to the Stiffness of Their Substrate
2005 StandoutScience
The NAD(P)H Oxidase Homolog Nox4 Modulates Insulin-Stimulated Generation of H2O2 and Plays an Integral Role in Insulin Signal Transduction
2004
Mitochondrial Fission, Fusion, and Stress
2012 StandoutScience
Signal transduction by reactive oxygen species
2011 Standout
Role for Mitochondrial Oxidants as Regulators of Cellular Metabolism
2000
Orchestrating Redox Signaling Networks through Regulatory Cysteine Switches
2009
Domain structure of a mammalian myosin I beta.
1994 StandoutNobel
Prostaglandins and Leukotrienes: Advances in Eicosanoid Biology
2001 StandoutScience
Serotonin stimulates mitogen-activated protein kinase activity through the formation of superoxide anion
1999
Wound Healing--Aiming for Perfect Skin Regeneration
1997 StandoutScience
Cysteine-Mediated Redox Signaling: Chemistry, Biology, and Tools for Discovery
2013
Polymerizing Microtubules Activate Site-directed F-Actin Assembly in Nerve Growth Cones
1999
Rho GTPases and the Actin Cytoskeleton
1998 StandoutScience
Oxidative Stress: An Essential Factor in the Pathogenesis of Gastrointestinal Mucosal Diseases
2014 Standout
Organelle-Targetable Fluorescent Probes for Imaging Hydrogen Peroxide in Living Cells via SNAP-Tag Protein Labeling
2010
CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES
1997 Standout
Reversible oxidation and inactivation of the tumor suppressor PTEN in cells stimulated with peptide growth factors
2004
A crucial role for Nox 1 in redox‐dependent regulation of Wnt‐β‐catenin signaling
2012
Employment of the Epidermal Growth Factor Receptor in Growth Factor–Independent Signaling Pathways
1999
Peroxiredoxin Evolution and the Regulation of Hydrogen Peroxide Signaling
2003 Science
Involvement of lipoxygenase in lysophosphatidic acid-stimulated hydrogen peroxide release in human HaCaT keratinocytes
2000
Cancer Genome Landscapes
2013 StandoutScience
Reactive oxygen species are critical for the growth and differentiation of medullary thyroid carcinoma cells.
2000
Spacious phagosome formation within mouse macrophages correlates with Salmonella serotype pathogenicity and host susceptibility
1995
Ca2+Sensitivity of Smooth Muscle and Nonmuscle Myosin II: Modulated by G Proteins, Kinases, and Myosin Phosphatase
2003 Standout
Localization and specificity of the phospholipid and actin binding sites on the tail of Acanthamoeba myosin IC
1992
Reactive Oxygen Species: A Breath of Life or Death?
2007
Imaging the glycome
2008 StandoutNobel
Cytoplasmic dynamics of myosin IIA and IIB: spatial ‘sorting’ of isoforms in locomoting cells
1998
Rapid Phosphorylation of Heterogeneous Nuclear Ribonucleoprotein C1/C2 in Response to Physiologic Levels of Hydrogen Peroxide in Human Endothelial Cells
2002
Reactive oxygen species, cell signaling, and cell injury
2000
Ras‐dependent and ‐independent regulation of reactive oxygen species by mitogenic growth factors and TGF‐β1
2000
Activation of the JAK-STAT pathway by reactive oxygen species
1998
Induction of Endothelial NO Synthase by Hydrogen Peroxide via a Ca 2+ /Calmodulin-Dependent Protein Kinase II/Janus Kinase 2–Dependent Pathway
2001
Phospholipase A2Enzymes: Physical Structure, Biological Function, Disease Implication, Chemical Inhibition, and Therapeutic Intervention
2011 Standout
myoA of Aspergillus nidulans encodes an essential myosin I required for secretion and polarized growth.
1995
Mammalian myosin I alpha, I beta, and I gamma: new widely expressed genes of the myosin I family.
1993
Molecular Basis for Interactions of G Protein βγ Subunits with Effectors
1998 StandoutScienceNobel
From Sulfenylation to Sulfhydration: What a Thiolate Needs to Tolerate
2012
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Free Radicals in the Physiological Control of Cell Function
2002 Standout
Myosin-I moves actin filaments on a phospholipid substrate: implications for membrane targeting.
1992
Regulation of ROS signal transduction by NADPH oxidase 4 localization
2008

Works of Ivan Baines being referenced

Identification of a New Type of Mammalian Peroxiredoxin That Forms an Intramolecular Disulfide as a Reaction Intermediate
2000
Localization of actobindin, profilin I, profilin II, and phosphatidylinositol-4,5-bisphosphate (PIP2) inAcanthamoeba castellanii
1998
Inhibition of contractile vacuole function in vivo by antibodies against myosin-I
1993 Nature
Dynamic localization of myosin‐I to endocytic structures in Acanthamoeba
2002
Characterization of a Mammalian Peroxiredoxin That Contains One Conserved Cysteine
1998
Epidermal Growth Factor (EGF)-induced Generation of Hydrogen Peroxide
1997 Standout
Xenopus nonmuscle myosin heavy chain isoforms have different subcellular localizations and enzymatic activities.
1996
Immunolocalization of myosin I heavy chain kinase in Acanthamoeba castellanii and binding of purified kinase to isolated plasma membranes.
1991
Differential localization of Acanthamoeba myosin I isoforms.
1992
[2] Purification of myosin I and myosin I heavy chain kinase from Acanthamoeba castellanii
1991
Localization of myosin IC and myosin II in Acanthamoeba castellanii by indirect immunofluorescence and immunogold electron microscopy.
1990
Mammalian Peroxiredoxin Isoforms Can Reduce Hydrogen Peroxide Generated in Response to Growth Factors and Tumor Necrosis Factor-α
1998
Rankless by CCL
2026