Citation Impact
Citing Papers
Complement drives Th17 cell differentiation and triggers autoimmune arthritis
2010 StandoutNobel
Programmed cell death 1 inhibits inflammatory helper T-cell development through controlling the innate immune response
2013 StandoutNobel
A noninflammatory mRNA vaccine for treatment of experimental autoimmune encephalomyelitis
2021 StandoutScienceNobel
Dendritic cell–expanded, islet-specific CD4+ CD25+ CD62L+ regulatory T cells restore normoglycemia in diabetic NOD mice
2007 StandoutNobel
Toll Pathway-Dependent Blockade of CD4 + CD25 + T Cell-Mediated Suppression by Dendritic Cells
2003 StandoutScience
Selective delivery of β cell antigen to dendritic cells in vivo leads to deletion and tolerance of autoreactive CD8 + T cells in NOD mice
2008 StandoutNobel
High prevalence of low affinity peptide–MHC II tetramer–negative effectors during polyclonal CD4+ T cell responses
2011
Homeostatic maintenance of natural Foxp3 + CD25+ CD4+ regulatory T cells by interleukin (IL)-2 and induction of autoimmune disease by IL-2 neutralization
2005 StandoutNobel
A mechanosensory complex that mediates the endothelial cell response to fluid shear stress
2005 StandoutNature
IFN-γ and IL-17 Production in Experimental Autoimmune Encephalomyelitis Depends on Local APC–T Cell Complement Production
2008
Autoimmune Th17 Cells Induced Synovial Stromal and Innate Lymphoid Cell Secretion of the Cytokine GM-CSF to Initiate and Augment Autoimmune Arthritis
2018 StandoutNobel
Bhlhe40 controls cytokine production by T cells and is essential for pathogenicity in autoimmune neuroinflammation
2014
Satb1 regulates the effector program of encephalitogenic tissue Th17 cells in chronic inflammation
2019 StandoutNobel
Transcription Factor Bhlhe40 in Immunity and Autoimmunity
2020
Re-establishing immunological self-tolerance in autoimmune disease
2012 StandoutNobel
The development of Cop 1 (Copaxone®), and innovative drug for the treatment of multiple sclerosis: personal reflections
1996
Vedolizumab as Induction and Maintenance Therapy for Ulcerative Colitis
2013 Standout
The Orphan Nuclear Receptor RORγt Directs the Differentiation Program of Proinflammatory IL-17+ T Helper Cells
2006 Standout
ICOS co-stimulatory receptor is essential for T-cell activation and function
2001 StandoutNatureNobel
Experimental in vivo and in vitro models of multiple sclerosis: EAE and beyond
2011
Regulatory T cells exert checks and balances on self tolerance and autoimmunity
2009 StandoutNobel
Immunological update on multiple sclerosis
2001
Enhancement of Th2 response in IL-6-deficient mice immunized with myelin oligodendrocyte glycoprotein
2000
Mechanisms Underlying Inflammation in Neurodegeneration
2010 Standout
A new approach for evaluating antigen-specific T cell responses to myelin antigens during the course of multiple sclerosis
2003
Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation
2014 StandoutNobel
Active induction of experimental allergic encephalomyelitis
2006
Cytokines and Chemokines as Mediators of Protection and Injury in the Central Nervous System Assessed in Transgenic Mice
2002
Reciprocal regulation of the Il9 locus by counteracting activities of transcription factors IRF1 and IRF4
2017 StandoutNobel
Multiple sclerosis candidate autoantigens except myelin oligodendrocyte glycoprotein are transcribed in human thymus
2002
PD-1/PD-L1, but not PD-1/PD-L2, interactions regulate the severity of experimental autoimmune encephalomyelitis
2006
IL-21 initiates an alternative pathway to induce proinflammatory TH17 cells
2007 StandoutNature
Increased reactivity to myelin oligodendrocyte glycoprotein peptides and epitope mapping in HLA DR2(15)+ multiple sclerosis
1998
Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1–deficient mice
2002
Multiple sclerosis
2008 Standout
On the role of tumor necrosis factor and receptors in models of multiorgan failure, rheumatoid arthritis, multiple sclerosis and inflammatory bowel disease
1999
Structural and functional features of central nervous system lymphatic vessels
2015 StandoutNature
Understanding pathogenesis and therapy of multiple sclerosis via animal models: 70 years of merits and culprits in experimental autoimmune encephalomyelitis research
2006
Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells
2006 StandoutNature
Microarray analysis of gene expression in multiple sclerosis and EAE identifies 5-lipoxygenase as a component of inflammatory lesions
2001
Interleukin-17 and Type 17 Helper T Cells
2009 Standout
The origin and application of experimental autoimmune encephalomyelitis
2007
Specificity of autoantibodies to epitopes of myelin proteins in multiple sclerosis
2002
Soluble Interleukin-6 (IL-6) Receptor/IL-6 Fusion Protein Enhances in Vitro Differentiation of Purified Rat Oligodendroglial Lineage Cells
2002
CD4 T‐cell epitopes of human α B‐crystallin
2004
IL-6-deficient mice are resistant to the induction of experimental autoimmune encephalomyelitis provoked by myelin oligodendrocyte glycoprotein
1998
Systemic Lupus Erythematosus
2011 Standout
Immunological Unresponsiveness Characterized by Increased Expression of CD5 on Peripheral T Cells Induced by Dendritic Cells In Vivo
2004
IL-6-deficient mice resist myelin oligodendrocyte glycoprotein-induced autoimmune encephalomyelitis
1998
Recognition of Commensal Microflora by Toll-Like Receptors Is Required for Intestinal Homeostasis
2004 Standout
Inflammation and cancer: back to Virchow?
2001 Standout
Dendritic Cells In Vivo: A Key Target for a New Vaccine Science
2008 StandoutNobel
Antibody Association with a Novel Model for Primary Progressive Multiple Sclerosis: Induction of Relapsing‐Remitting and Progressive Forms of EAE in H2S Mouse Strains
2000
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Multiple Sclerosis
2000 Standout
Multiple sclerosis: B- and T-cell responses to the extracellular domain of the myelin oligodendrocyte glycoprotein
1999
In vitro evidence that subcutaneous administration of glatiramer acetate induces hyporesponsive T cells in patients with multiple sclerosis
2003
Immune Tolerance to Myelin Proteins
2003
Enhancement of EAE and induction of autoantibodies to T-cell epitopes in mice infected with a recombinant vaccinia virus encoding myelin proteolipid protein
1997
Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
2024 StandoutNobel
IL-6 plays a crucial role in the induction phase of myelin oligodendrocyte glycoprotein 35–55 induced experimental autoimmune encephalomyelitis
1999
CD62L Is Required on Effector Cells for Local Interactions in the CNS to Cause Myelin Damage in Experimental Allergic Encephalomyelitis
2001
TGF-β-induced Foxp3 inhibits TH17 cell differentiation by antagonizing RORγt function
2008 StandoutNature
B cells regulate autoimmunity by provision of IL-10
2002
An Immunomodulatory Molecule of Symbiotic Bacteria Directs Maturation of the Host Immune System
2005 Standout
T‐ and B‐cell responses to myelin oligodendrocyte glycoprotein in experimental autoimmune encephalomyelitis and multiple sclerosis
2001
Myelin Oligodendrocyte Glycoprotein–specific T Cell Receptor Transgenic Mice Develop Spontaneous Autoimmune Optic Neuritis
2003
Kinetics and Cellular Origin of Cytokines in the Central Nervous System: Insight into Mechanisms of Myelin Oligodendrocyte Glycoprotein-Induced Experimental Autoimmune Encephalomyelitis
2000
Structural Basis for Gluten Intolerance in Celiac Sprue
2002 StandoutScience
Intensified and protective CD4+ T cell immunity in mice with anti–dendritic cell HIV gag fusion antibody vaccine
2006 StandoutNobel
Expansion of FOXP3high regulatory T cells by human dendritic cells (DCs) in vitro and after injection of cytokine-matured DCs in myeloma patients
2006 StandoutNobel
Cis3/Socs3/Ssi3 Plays a Negative Regulatory Role in Stat3 Activation and Intestinal Inflammation
2001
Differential Effects of IL-21 during Initiation and Progression of Autoimmunity against Neuroantigen
2005
Induction and Suppression of an Autoimmune Disease by Oligomerized T Cell Epitopes
2000
IL-6 Inhibits the Tolerogenic Function of CD8α+ Dendritic Cells Expressing Indoleamine 2,3-Dioxygenase
2001
Multiple Sclerosis
2018 Standout
Antagonizing the α4β1 Integrin, but Not α4β7, Inhibits Leukocytic Infiltration of the Central Nervous System in Rhesus Monkey Experimental Autoimmune Encephalomyelitis
2013
IL-17 and Th17 Cells
2009 Standout
Type I Diabetes and Multiple Sclerosis Patients Target Islet Plus Central Nervous System Autoantigens; Nonimmunized Nonobese Diabetic Mice Can Develop Autoimmune Encephalitis
2001
Natural Recovery and Protection from Autoimmune Encephalomyelitis: Contribution of CD4+CD25+ Regulatory Cells within the Central Nervous System
2005
IMMUNOLOGY OF MULTIPLE SCLEROSIS
2005 Standout
The Linkage of Innate to Adaptive Immunity via Maturing Dendritic Cells In Vivo Requires CD40 Ligation in Addition to Antigen Presentation and CD80/86 Costimulation
2004 StandoutNobel
Cytokine Storm
2020 Standout
Inflammatory Blockade Restores Adult Hippocampal Neurogenesis
2003 StandoutScience
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Biology of Oligodendrocyte and Myelin in the Mammalian Central Nervous System
2001 Standout
Superantigen overcomes resistance of IL‐6‐deficient mice towards MOG‐induced EAE by a TNFR1 controlled pathway
2001
Regulation of Experimental Autoimmune Encephalomyelitis by Natural Killer (NK) Cells
1997
Increased CD8+ Cytotoxic T Cell Responses to Myelin Basic Protein in Multiple Sclerosis
2004
Cutting Edge: CD4+CD25+ Regulatory T Cells Suppress Antigen-Specific Autoreactive Immune Responses and Central Nervous System Inflammation During Active Experimental Autoimmune Encephalomyelitis
2002
High prevalence of autoreactive, neuroantigen-specific CD8+ T cells in multiple sclerosis revealed by novel flow cytometric assay
2004
A Critical Role for Lymphotoxin in Experimental Allergic Encephalomyelitis
1997
In vivo expansion of T reg cells with IL-2–mAb complexes: induction of resistance to EAE and long-term acceptance of islet allografts without immunosuppression
2009
Receptor for advanced glycation end products (RAGE) regulates sepsis but not the adaptive immune response
2004 Standout
Tolerogenic Dendritic Cells
2003 StandoutNobel
Flt3L controls the development of radiosensitive dendritic cells in the meninges and choroid plexus of the steady-state mouse brain
2011 StandoutNobel
B cell depletion therapy ameliorates autoimmune disease through ablation of IL-6–producing B cells
2012
Tissue-specific expression of B7x protects from CD4 T cell–mediated autoimmunity
2011 StandoutNobel
Antigen targeting to dendritic cells elicits long-lived T cell help for antibody responses
2006 StandoutNobel
A distinct subpopulation of CD25−T-follicular regulatory cells localizes in the germinal centers
2017 StandoutNobel
Myelin Antigen-Specific CD8+ T Cells Are Encephalitogenic and Produce Severe Disease in C57BL/6 Mice
2001
Extended use of glatiramer acetate (Copaxone) is well tolerated and maintains its clinical effect on multiple sclerosis relapse rate and degree of disability
1998
IL-6-Deficient Mice Are Resistant to Experimental Autoimmune Encephalomyelitis: Roles of IL-6 in the Activation and Differentiation of Autoreactive T Cells
1998
Altered vascular permeability and early onset of experimental autoimmune encephalomyelitis in PECAM-1–deficient mice
2002
The Human T Cell Response to Myelin Oligodendrocyte Glycoprotein: A Multiple Sclerosis Family-Based Study
2002
High Immunogenicity of Intracellular Myelin Oligodendrocyte Glycoprotein Epitopes
2002
Works of Itzhack Mendel being referenced
Chronic relapsing experimental autoimmune encephalomyelitis with a delayed onset and an atypical clinical course, induced in PL/J mice by myelin oligodendrocyte glycoprotein (MOG)‐derived peptide: Preliminary analysis of MOG T cell epitopes
1995
Predominance of the autoimmune response to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis: Reactivity to the extracellular domain of MOG is directed against three main regions
1997
A myelin oligodendrocyte glycoprotein peptide induces typical chronic experimental autoimmune encephalomyelitis in H‐2b mice: Fine specificity and T cell receptor Vβ expression of encephalitogenic T cells
1995
The central nervous sytem-specific myelin oligodendrocytic basic protein (MOBP) is encephalitogenic and a potential target antigen in multiple sclerosis (MS)
2000
The autoimmune reactivity to myelin oligodendrocyte glycoprotein (MOG) in multiple sclerosis is potentially pathogenic: Effect of copolymer 1 on MOG-induced disease
1996
Interleukin‐6 functions in autoimmune encephalomyelitis: a study in gene‐targeted mice
1998