Citation Impact
Citing Papers
Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition
2013 StandoutScience
The Transcription Factor Snail Induces Tumor Cell Invasion through Modulation of the Epithelial Cell Differentiation Program
2005
MicroRNA-200c mitigates invasiveness and restores sensitivity to microtubule-targeting chemotherapeutic agents
2009
Glycogen synthase kinase-3 is an endogenous inhibitor of Snail transcription
2005
SNAI1 Is Required for Tumor Growth and Lymph Node Metastasis of Human Breast Carcinoma MDA-MB-231 Cells
2007
High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells
2005 StandoutScience
Brachyury, a Driver of the Epithelial–Mesenchymal Transition, Is Overexpressed in Human Lung Tumors: An Opportunity for Novel Interventions against Lung Cancer
2012
Endothelin-1 Promotes Epithelial-to-Mesenchymal Transition in Human Ovarian Cancer Cells
2005
Kruppel-Like Factor 8 Induces Epithelial to Mesenchymal Transition and Epithelial Cell Invasion
2007
Reassessing Epithelial to Mesenchymal Transition as a Prerequisite for Carcinoma Invasion and Metastasis
2006
Highly Recurrent TERT Promoter Mutations in Human Melanoma
2013 StandoutScience
Suppression of the Epithelial–Mesenchymal Transition by Grainyhead-like-2
2012
A Novel Tankyrase Small-Molecule Inhibitor Suppresses APC Mutation–Driven Colorectal Tumor Growth
2013
An emerging role for class I bHLH E2-2 proteins in EMT regulation and tumor progression
2010
Slug expression is an independent prognostic parameter for poor survival in colorectal carcinoma patients
2006
miR-30 inhibits TGF-β1-induced epithelial-to-mesenchymal transition in hepatocyte by targeting Snail1
2011
Concordant Regulation of Gene Expression by Hypoxia and 2-Oxoglutarate-dependent Dioxygenase Inhibition
2006 StandoutNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
The class I bHLH factors E2-2A and E2-2B regulate EMT
2009
Transforming Growth Factor β-1 Induces Snail Transcription Factor in Epithelial Cell Lines
2003
Mouse Snail Is a Target Gene for HIF
2011
Inflammation and EMT: an alliance towards organ fibrosis and cancer progression
2009
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
The Hypoxia-controlled FBXL14 Ubiquitin Ligase Targets SNAIL1 for Proteasome Degradation
2009
Distinct EMT programs control normal mammary stem cells and tumour-initiating cells
2015 Nature
Slug is overexpressed in gastric carcinomas and may act synergistically with SIP1 and Snail in the down‐regulation of E‐cadherin
2007
Control of somatic tissue differentiation by the long non-coding RNA TINCR
2012 StandoutNature
HMGA2 Maintains Oncogenic RAS-Induced Epithelial-Mesenchymal Transition in Human Pancreatic Cancer Cells
2009
Unraveling signalling cascades for the Snail family of transcription factors
2004
Involvement of Members of the Cadherin Superfamily in Cancer
2009
A comparison of epithelial-to-mesenchymal transition and re-epithelialization
2012
Bile acids as carcinogens in human gastrointestinal cancers
2004
The Genetic Signatures of Noncoding RNAs
2009
ZEB1 represses E-cadherin and induces an EMT by recruiting the SWI/SNF chromatin-remodeling protein BRG1
2010
Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits
2009 Standout
Long non-coding RNAs in nervous system function and disease
2010
Circular RNAs are a large class of animal RNAs with regulatory potency
2013 StandoutNature
Can we safely target the WNT pathway?
2014
Stabilization of Snail by NF-κB Is Required for Inflammation-Induced Cell Migration and Invasion
2009
Non-coding RNAs as regulators of embryogenesis
2011
Expression of Snail protein in tumor–stroma interface
2006
Snai1 and Snai2 collaborate on tumor growth and metastasis properties of mouse skin carcinoma cell lines
2008
Snail silencing effectively suppresses tumour growth and invasiveness
2006
Modular regulatory principles of large non-coding RNAs
2012 StandoutNature
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
E-cadherin mutation and Snail overexpression as alternative mechanisms of E-cadherin inactivation in synovial sarcoma
2004
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
The role of long non-coding RNAs in genome formatting and expression
2015
Precision microbiome reconstitution restores bile acid mediated resistance to Clostridium difficile
2014 StandoutNature
Downregulation of caveolin-1 function by EGF leads to the loss of E-cadherin, increased transcriptional activity of β-catenin, and enhanced tumor cell invasion
2003
The Molecular Basis of Vitamin D Receptor and β-Catenin Crossregulation
2006
Wnt signaling in cancer
2016 Standout
Snail1 transcriptional repressor binds to its own promoter and controls its expression
2006
Claudin-1 regulates cellular transformation and metastatic behavior in colon cancer
2005
Lower levels of nuclear β‐catenin predict for a poorer prognosis in localized prostate cancer
2004
Snail and Slug are major determinants of ovarian cancer invasiveness at the transcription level
2005
RNA in unexpected places: long non-coding RNA functions in diverse cellular contexts
2013
New potential therapeutic targets to combat epithelial tumor invasion
2006
Raf 1 represses expression of the tight junction protein occludin via activation of the zinc-finger transcription factor slug
2006
WNT signalling pathways as therapeutic targets in cancer
2012 Standout
The emerging role of lncRNAs in cancer
2015 Standout
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
The expression levels of the transcriptional regulators p300 and CtBP modulate the correlations between SNAIL, ZEB1, E‐cadherin and vitamin D receptor in human colon carcinomas
2006
Long noncoding RNAs: Re-writing dogmas of RNA processing and stability
2015
Modulation of oxidative stress as an anticancer strategy
2013 Standout
Role of the epithelial-mesenchymal transition regulator Slug in primary human cancers
2009
Vitamin D Deficiency
2007 Standout
A ceRNA Hypothesis: The Rosetta Stone of a Hidden RNA Language?
2011 Standout
DeltaEF1 is a transcriptional repressor of E-cadherin and regulates epithelial plasticity in breast cancer cells
2005 Standout
Tankyrase-targeted therapeutics: expanding opportunities in the PARP family
2012
NF-κB represses E-cadherin expression and enhances epithelial to mesenchymal transition of mammary epithelial cells: potential involvement of ZEB-1 and ZEB-2
2006
ERβ Impedes Prostate Cancer EMT by Destabilizing HIF-1α and Inhibiting VEGF-Mediated Snail Nuclear Localization: Implications for Gleason Grading
2010
Androgen regulation of prostasin gene expression is mediated by sterol-regulatory element-binding proteins and SLUG
2006
The multilayered complexity of ceRNA crosstalk and competition
2014 StandoutNature
Snail in the frame of malignant tumor recurrence
2006
TGF-β and epithelial-to-mesenchymal transitions
2005
Paricalcitol Attenuates Renal Interstitial Fibrosis in Obstructive Nephropathy
2006
Bypassing cellular EGF receptor dependence through epithelial-to-mesenchymal-like transitions
2008
Epithelial-Mesenchymal Transition in tumor microenvironment
2011
Transcriptional regulation of cadherins during development and carcinogenesis
2004
Tight junction proteins
2002
A Long Noncoding RNA Controls Muscle Differentiation by Functioning as a Competing Endogenous RNA
2011 Standout
Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis
2015
FOXOs: signalling integrators for homeostasis maintenance
2013
Emergence of the Phosphoinositide 3-Kinase-Akt- Mammalian Target of Rapamycin Axis in Transforming Growth Factor-β-Induced Epithelial-Mesenchymal Transition
2010
Zinc transporter LIVI controls epithelial-mesenchymal transition in zebrafish gastrula organizer
2004 Nature
E-cadherin, β-catenin, and ZEB1 in malignant progression of cancer
2009
Noncoding RNA in development
2008
Large non-coding RNAs: missing links in cancer?
2010
Cis-acting noncoding RNAs: friends and foes
2012
Natural RNA circles function as efficient microRNA sponges
2013 StandoutNature
Immunity, Inflammation, and Cancer
2010 Standout
MUC1: A multifunctional cell surface component of reproductive tissue epithelia
2004
How to make a melanoma: what do we know of the primary clonal events?
2008
A long noncoding RNA maintains active chromatin to coordinate homeotic gene expression
2011 StandoutNature
Defining the E-Cadherin Repressor Interactome in Epithelial-Mesenchymal Transition: The PMC42 Model as a Case Study
2010
Vitamin D
2005
Human occludin is a hepatitis C virus entry factor required for infection of mouse cells
2009 StandoutNatureNobel
Snail, Zeb and bHLH factors in tumour progression: an alliance against the epithelial phenotype?
2007 Standout
Emerging Biological Principles of Metastasis
2017 Standout
Ajuba LIM Proteins Are Snail/Slug Corepressors Required for Neural Crest Development in Xenopus
2008
Slug Regulates Integrin Expression and Cell Proliferation in Human Epidermal Keratinocytes
2006
EMT: 2016
2016 Standout
Targeting metastasis
2016
Junk DNA and the long non-coding RNA twist in cancer genetics
2015
Epithelial-to-mesenchymal transition of peritoneal mesothelial cells is regulated by an ERK/NF-κB/Snail1 pathway
2008
Claudin-1 is a hepatitis C virus co-receptor required for a late step in entry
2007 StandoutNatureNobel
Unique features of long non-coding RNA biogenesis and function
2015 Standout
Wnt-dependent Regulation of the E-cadherin Repressor Snail
2005
Snail1 is stabilized by O‐GlcNAc modification in hyperglycaemic condition
2010
The hallmarks of cancer
2012 Standout
F-box proteins: Keeping the epithelial-to-mesenchymal transition (EMT) in check
2015
EMT-activating transcription factors in cancer: beyond EMT and tumor invasiveness
2012
Exosomes facilitate therapeutic targeting of oncogenic KRAS in pancreatic cancer
2017 StandoutNature
Molecular signature and therapeutic perspective of the epithelial-to-mesenchymal transitions in epithelial cancers
2008
Thymosin β4 triggers an epithelial–mesenchymal transition in colorectal carcinoma by upregulating integrin-linked kinase
2006
Transmembrane proteins of tight junctions
2007
Interaction with Suv39H1 is critical for Snail-mediated E-cadherin repression in breast cancer
2012
E-cadherin and vitamin D receptor regulation by SNAIL and ZEB1 in colon cancer: clinicopathological correlations
2005
Role of CK1 in GSK3β-mediated phosphorylation and degradation of Snail
2010
A Novel Network Integrating a miRNA-203/SNAI1 Feedback Loop which Regulates Epithelial to Mesenchymal Transition
2012
Lats2 kinase potentiates Snail1 activity by promoting nuclear retention upon phosphorylation
2011
Dual regulation of Snail by GSK-3β-mediated phosphorylation in control of epithelial–mesenchymal transition
2004
eEF1A Mediates the Nuclear Export of SNAG-Containing Proteins via the Exportin5-Aminoacyl-tRNA Complex
2013
A molecular role for lysyl oxidase‐like 2 enzyme in Snail regulation and tumor progression
2005
The SNAG domain of Snail1 functions as a molecular hook for recruiting lysine‐specific demethylase 1
2010
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Evolutionary functional analysis and molecular regulation of the ZEB transcription factors
2012
Long non-coding RNA HOTAIR reprograms chromatin state to promote cancer metastasis
2010 StandoutNature
Mouse cDNA microarray analysis uncovers Slug targets in mouse embryonic fibroblasts
2005
lincRNAs act in the circuitry controlling pluripotency and differentiation
2011 StandoutNature
Snail controls differentiation of hepatocytes by repressing HNF4α expression
2006
Raf plus TGFβ-dependent EMT is initiated by endocytosis and lysosomal degradation of E-cadherin
2006
TGF-β-induced epithelial to mesenchymal transition
2009 Standout
UDP-glucose accelerates SNAI1 mRNA decay and impairs lung cancer metastasis
2019 Nature
Gene regulation by antisense transcription
2013
Epithelial–mesenchymal transitions in development and pathologies
2003
Non-coding RNAs take centre stage in epithelial-to-mesenchymal transition
2008
Long noncoding RNAs: functional surprises from the RNA world
2009 Standout
miRNA‐dependent gene silencing involving Ago2‐mediated cleavage of a circular antisense RNA
2011
Long non-coding RNAs: insights into functions
2009 Standout
Regulatory networks defining EMT during cancer initiation and progression
2013 Standout
Transcriptional regulation of cell polarity in EMT and cancer
2008
MEMO1, a new IRS1-interacting protein, induces epithelial–mesenchymal transition in mammary epithelial cells
2012
Overexpression of NBS1 induces epithelial–mesenchymal transition and co-expression of NBS1 and Snail predicts metastasis of head and neck cancer
2006
The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells
2008 Standout
CD44 splice isoform switching in human and mouse epithelium is essential for epithelial-mesenchymal transition and breast cancer progression
2011
Functional Cooperation between Snail1 and Twist in the Regulation of ZEB1 Expression during Epithelial to Mesenchymal Transition
2011
LncRNA: A link between RNA and cancer
2014
Analysis of the E-Cadherin Repressor Snail in Primary Human Cancers
2007
MicroRNA-146a directs the symmetric division of Snail-dominant colorectal cancer stem cells
2014
Convergence of Wnt, ß-Catenin, and Cadherin Pathways
2004 StandoutScience
TGF-β–induced epithelial-to-mesenchymal transition proceeds through stepwise activation of multiple feedback loops
2014
Genome Regulation by Long Noncoding RNAs
2012 Standout
Snail-dependent and -independent Epithelial-Mesenchymal Transition in Oral Squamous Carcinoma Cells
2006
RNA–protein analysis using a conditional CRISPR nuclease
2013 StandoutNobel
Zeb1 links epithelial-mesenchymal transition and cellular senescence
2008
The Snail genes as inducers of cell movement and survival: implications in development and cancer
2005
The Transcription Factor ZEB1 Is Aberrantly Expressed in Aggressive Uterine Cancers
2006
The transcription factors Slug and Snail act as repressors of Claudin-1 expression in epithelial cells
2006
Repression of Prostaglandin Dehydrogenase by Epidermal Growth Factor and Snail Increases Prostaglandin E2 and Promotes Cancer Progression
2006
Involvement of Ets-1 transcription factor in inducing matrix metalloproteinase-2 expression by epithelial-mesenchymal transition in human squamous carcinoma cells
2006
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Snail blocks the cell cycle and confers resistance to cell death
2004
Notch signaling mediates hypoxia-induced tumor cell migration and invasion
2008
Tumor Budding: The Name is EMT. Partial EMT.
2016
Pak1 Phosphorylation of Snail, a Master Regulator of Epithelial-to-Mesenchyme Transition, Modulates Snail's Subcellular Localization and Functions
2005
Polycomb Complex 2 Is Required for E-cadherin Repression by the Snail1 Transcription Factor
2008
Constitutively Active Type I Insulin-Like Growth Factor Receptor Causes Transformation and Xenograft Growth of Immortalized Mammary Epithelial Cells and Is Accompanied by an Epithelial-to-Mesenchymal Transition Mediated by NF-κB and Snail
2007
MicroRNA-based regulation of epithelial–hybrid–mesenchymal fate determination
2013
The Ins and Outs of the Epithelial to Mesenchymal Transition in Health and Disease
2011
Hepatocyte-Derived Snail1 Propagates Liver Fibrosis Progression
2011
The Role of Vitamin D in Cancer Prevention
2005 Standout
Metabolic reprogramming and cancer progression
2020 StandoutScience
Cancer development induced by graded expression of Snail in mice
2005
Cyclooxygenase-2–Dependent Regulation of E-Cadherin: Prostaglandin E2 Induces Transcriptional Repressors ZEB1 and Snail in Non–Small Cell Lung Cancer
2006
Chemically tunable mucin chimeras assembled on living cells
2015 StandoutNobel
Snail and Slug Mediate Radioresistance and Chemoresistance by Antagonizing p53-Mediated Apoptosis and Acquiring a Stem-Like Phenotype in Ovarian Cancer Cells
2009
Long Non-Coding RNAs: Challenges for Diagnosis and Therapies
2013
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Expression and nuclear localization of Snail, an E-cadherin repressor, in adenocarcinomas of the upper gastrointestinal tract
2005
Upregulation of MMP-9 in MDCK epithelial cell line in response to expression of the Snail transcription factor
2005
Insulin-like Growth Factor-I–Dependent Up-regulation of ZEB1 Drives Epithelial-to-Mesenchymal Transition in Human Prostate Cancer Cells
2008
Epithelial Plasticity: A Common Theme in Embryonic and Cancer Cells
2013 StandoutScience
Slug Expression in the E-cadherin Preserved Tumors Is Related to Prognosis in Patients with Esophageal Squamous Cell Carcinoma
2005
Stability of the hybrid epithelial/mesenchymal phenotype
2016
Repression of PTEN Phosphatase by Snail1 Transcriptional Factor during Gamma Radiation-Induced Apoptosis
2008
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Noncalcemic Actions of Vitamin D Receptor Ligands
2005
Epithelial to Mesenchymal Transition Is a Determinant of Sensitivity of Non–Small-Cell Lung Carcinoma Cell Lines and Xenografts to Epidermal Growth Factor Receptor Inhibition
2005
Loss of homotypic cell adhesion by epithelial-mesenchymal transition or mutation limits sensitivity to epidermal growth factor receptor inhibition
2007
Canonical Wnt signaling regulates Slug activity and links epithelial–mesenchymal transition with epigenetic Breast Cancer 1, Early Onset (BRCA1) repression
2012
Transcription RepressorSlugPromotes Carcinoma Invasion and Predicts Outcome of Patients with Lung Adenocarcinoma
2005
Epithelial versus Mesenchymal Phenotype Determines In vitro Sensitivity and Predicts Clinical Activity of Erlotinib in Lung Cancer Patients
2005
Characterization of Snail nuclear import pathways as representatives of C2H2 zinc finger transcription factors
2009
The epithelial–mesenchymal transition: new insights in signaling, development, and disease
2006 Standout
Slug stability is dynamically regulated during neural crest development by the F-box protein Ppa
2006
Works of Isabel Puig being referenced
β-catenin confers resistance to PI3K and AKT inhibitors and subverts FOXO3a to promote metastasis in colon cancer
2012
Regulation of Snail transcription during epithelial to mesenchymal transition of tumor cells
2004
A natural antisense transcript regulates Zeb2/Sip1 gene expression during Snail1-induced epithelial–mesenchymal transition
2008
Activation of NF-κB by Akt upregulates Snail expression and induces epithelium mesenchyme transition
2007
The transcription factor SNAIL represses vitamin D receptor expression and responsiveness in human colon cancer
2004
Wilms' Tumor Protein Induces an Epithelial-Mesenchymal Hybrid Differentiation State in Clear Cell Renal Cell Carcinoma
2014
Snail Induction of Epithelial to Mesenchymal Transition in Tumor Cells Is Accompanied by MUC1 Repression andZEB1 Expression
2002
Phosphorylation Regulates the Subcellular Location and Activity of the Snail Transcriptional Repressor
2003
Vitamin D3 promotes the differentiation of colon carcinoma cells by the induction of E-cadherin and the inhibition of β-catenin signaling
2001