Citation Impact
Citing Papers
Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition
2013 StandoutScience
Quantitative Detection of EGFR Mutations in Circulating Tumor DNA Derived from Lung Adenocarcinomas
2011
TGFα and Amphiregulin Paracrine Network Promotes Resistance to EGFR Blockade in Colorectal Cancer Cells
2014
Structures of the CXCR4 Chemokine GPCR with Small-Molecule and Cyclic Peptide Antagonists
2010 StandoutScience
Cell types in the mouse cortex and hippocampus revealed by single-cell RNA-seq
2015 StandoutScience
Nucleic acid detection with CRISPR-Cas13a/C2c2
2017 StandoutScience
Programmable RNA recognition using a CRISPR-associated Argonaute
2018 StandoutNobel
Maturation-Dependent HIV-1 Surface Protein Redistribution Revealed by Fluorescence Nanoscopy
2012 StandoutScienceNobel
Digital RNA sequencing minimizes sequence-dependent bias and amplification noise with optimized single-molecule barcodes
2012
Clinical Applications of Circulating Tumor Cells and Circulating Tumor DNA as Liquid Biopsy
2016
Noninvasive Detection of Response and Resistance in EGFR -Mutant Lung Cancer Using Quantitative Next-Generation Genotyping of Cell-Free Plasma DNA
2014
The Effect of Preservative and Temperature on the Analysis of Circulating Tumor DNA
2016
Detection of ultra-rare mutations by next-generation sequencing
2012
Ultrasensitive Measurement of Hotspot Mutations in Tumor DNA in Blood Using Error-Suppressed Multiplexed Deep Sequencing
2012
fastp: an ultra-fast all-in-one FASTQ preprocessor
2018 Standout
Abnormal plasma DNA profiles in early ovarian cancer using a non-invasive prenatal testing platform: implications for cancer screening
2016
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Changes in Colorectal Carcinoma Genomes under Anti-EGFR Therapy Identified by Whole-Genome Plasma DNA Sequencing
2014
Detection of Clonal and Subclonal Copy-Number Variants in Cell-Free DNA from Patients with Breast Cancer Using a Massively Multiplexed PCR Methodology
2015
Mutational landscape and significance across 12 major cancer types
2013 StandoutNature
Quantitative assessment of BRAF V600 mutant circulating cell-free tumor DNA as a tool for therapeutic monitoring in metastatic melanoma patients treated with BRAF/MEK inhibitors
2016
Hallmarks of Cancer: The Next Generation
2011 Standout
High Glucose Triggers Nucleotide Imbalance through O-GlcNAcylation of Key Enzymes and Induces KRAS Mutation in Pancreatic Cells
2019
Cell-free circulating tumor DNA in cancer
2016
HIV-1 Gag Processing Intermediates Trans-dominantly Interfere with HIV-1 Infectivity
2009
Protein Conformational Switches: From Nature to Design
2012
Therapy-induced tumour secretomes promote resistance and tumour progression
2015 Nature
Cancer Evolution and the Limits of Predictability in Precision Cancer Medicine
2016
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Pancreatic cancer
2004 Standout
Early stage NSCLC — challenges to implementing ctDNA-based screening and MRD detection
2018
A view on drug resistance in cancer
2019 StandoutNature
Single-cell sequencing-based technologies will revolutionize whole-organism science
2013
Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu
2008 StandoutNature
Liquid biopsy: monitoring cancer-genetics in the blood
2013
Early detection of nasopharyngeal carcinoma by plasma Epstein‐Barr virus DNA analysis in a surveillance program
2013
Circulating cell free DNA: Preanalytical considerations
2013
A Big Bang model of human colorectal tumor growth
2015
The biology and management of non-small cell lung cancer
2018 StandoutNature
Circulating Cell-Free DNA from Colorectal Cancer Patients May Reveal High KRAS or BRAF Mutation Load
2013
Integrating liquid biopsies into the management of cancer
2017
A spatial model predicts that dispersal and cell turnover limit intratumour heterogeneity
2015 Nature
Genomic Alterations in Liquid Biopsies from Patients with Bladder Cancer
2016
Circulating tumour cells and cell-free DNA as tools for managing breast cancer
2013
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
Genetic instabilities in human cancers
1998 StandoutNature
Epithelial-to-mesenchymal transition is dispensable for metastasis but induces chemoresistance in pancreatic cancer
2015 StandoutNature
Converting Cancer Therapies into Cures: Lessons from Infectious Diseases
2012
A genetic model for colorectal tumorigenesis
1990 Standout
Origins of Metastatic Traits
2013
Distant metastasis occurs late during the genetic evolution of pancreatic cancer
2010 StandoutNature
Carrier molecules and extraction of circulating tumor DNA for next generation sequencing in colorectal cancer
2016
Analysis of Circulating Tumor DNA to Monitor Metastatic Breast Cancer
2013 Standout
Systemic sclerosis
2017 Standout
Optimised Pre-Analytical Methods Improve KRAS Mutation Detection in Circulating Tumour DNA (ctDNA) from Patients with Non-Small Cell Lung Cancer (NSCLC)
2016
Tumor-associated copy number changes in the circulation of patients with prostate cancer identified through whole-genome sequencing
2013
Detection of ubiquitous and heterogeneous mutations in cell-free DNA from patients with early-stage non-small-cell lung cancer
2016
EGFR mutation detection in ctDNA from NSCLC patient plasma: A cross-platform comparison of leading technologies to support the clinical development of AZD9291
2015
CRISPR-Barcoding for Intratumor Genetic Heterogeneity Modeling and Functional Analysis of Oncogenic Driver Mutations
2016
The Long and Short of Circulating Cell-Free DNA and the Ins and Outs of Molecular Diagnostics
2016
Plasma Membrane Is the Site of Productive HIV-1 Particle Assembly
2006
Insight into the heterogeneity of breast cancer through next-generation sequencing
2011
Detecting ultralow-frequency mutations by Duplex Sequencing
2014
Whole-genome plasma sequencing reveals focal amplifications as a driving force in metastatic prostate cancer
2016
Analytical and Clinical Validation of a Digital Sequencing Panel for Quantitative, Highly Accurate Evaluation of Cell-Free Circulating Tumor DNA
2015
MX2 is an interferon-induced inhibitor of HIV-1 infection
2013 StandoutNatureNobel
Capturing intra-tumor genetic heterogeneity by de novo mutation profiling of circulating cell-free tumor DNA: a proof-of-principle
2014
Nanopore sequencing detects structural variants in cancer
2016
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Liquid biopsies come of age: towards implementation of circulating tumour DNA
2017 Standout
Cell-free DNA Comprises an In Vivo Nucleosome Footprint that Informs Its Tissues-Of-Origin
2016
Human Correlates of Provocative Questions in Pancreatic Pathology
2012
Non-invasive analysis of acquired resistance to cancer therapy by sequencing of plasma DNA
2013 Nature
Analysis of Plasma Epstein–Barr Virus DNA to Screen for Nasopharyngeal Cancer
2017
Characterizing the patterns of clonal selection in circulating tumor DNA from patients with colorectal cancer refractory to anti-EGFR treatment
2015
De novo design of bioactive protein switches
2019 StandoutNatureNobel
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Inhibition of HIV-1 Particle Assembly by 2′,3′-Cyclic-Nucleotide 3′-Phosphodiesterase
2012 StandoutNobel
An ultrasensitive method for quantitating circulating tumor DNA with broad patient coverage
2014 Standout
Direct mutation analysis by high-throughput sequencing: From germline to low-abundant, somatic variants
2011
Advances in understanding cancer genomes through second-generation sequencing
2010
Extreme Genetic Fragility of the HIV-1 Capsid
2013
Clinical validation of the detection of KRAS and BRAF mutations from circulating tumor DNA
2014
Use of cancer‐specific genomic rearrangements to quantify disease burden in plasma from patients with solid tumors
2010
Integrated digital error suppression for improved detection of circulating tumor DNA
2016
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Low Input Whole-Exome Sequencing to Determine the Representation of the Tumor Exome in Circulating DNA of Non-Small Cell Lung Cancer Patients
2016
Ultrasensitive Detection of Multiplexed Somatic Mutations Using MALDI-TOF Mass Spectrometry
2015
Clonal evolution in cancer
2012 StandoutNature
Genomic Analysis of Uterine Lavage Fluid Detects Early Endometrial Cancers and Reveals a Prevalent Landscape of Driver Mutations in Women without Histopathologic Evidence of Cancer: A Prospective Cross-Sectional Study
2016
The Hallmarks of Aging
2013 Standout
Comparative analysis of circulating tumor DNA stability In K3EDTA, Streck, and CellSave blood collection tubes
2016
Establishing the origin of metastatic deposits in the setting of multiple primary malignancies: The role of massively parallel sequencing
2013
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Origins, structures, and functions of circulating DNA in oncology
2016
Oncogene addiction in non-small cell lung cancer: Focus on ROS1 inhibition
2017
Counting absolute numbers of molecules using unique molecular identifiers
2011
Discovery and saturation analysis of cancer genes across 21 tumour types
2014 StandoutNature
Tumour evolution inferred by single-cell sequencing
2011 StandoutNature
Circulating tumor DNA analysis as a real-time method for monitoring tumor burden in melanoma patients undergoing treatment with immune checkpoint blockade
2014
Elimination of unaltered DNA in mixed clinical samples via nuclease-assisted minor-allele enrichment
2016
Performance of Streck cfDNA Blood Collection Tubes for Liquid Biopsy Testing
2016
Feedback and redundancy in receptor tyrosine kinase signaling: relevance to cancer therapies
2014
Pancreatic cancer
2011 Standout
Exploratory Analysis of TP53 Mutations in Circulating Tumour DNA as Biomarkers of Treatment Response for Patients with Relapsed High-Grade Serous Ovarian Carcinoma: A Retrospective Study
2016
Analysis of circulating tumour DNA to monitor disease burden following colorectal cancer surgery
2015
Serial monitoring of circulating tumor DNA in patients with primary breast cancer for detection of occult metastatic disease
2015
Cancer biomarkers: Written in blood
2014 Nature
Exploring the Genomes of Cancer Cells: Progress and Promise
2011 Science
Brain Tumor Mutations Detected in Cerebral Spinal Fluid
2015
Differential strand separation at critical temperature: A minimally disruptive enrichment method for low-abundance unknown DNA mutations
2012
Plasma DNA tissue mapping by genome-wide methylation sequencing for noninvasive prenatal, cancer, and transplantation assessments
2015
Maternal Plasma DNA Sequencing Reveals the Genome-Wide Genetic and Mutational Profile of the Fetus
2010
Coinhibitory Pathways in Immunotherapy for Cancer
2016
Circulating tumor DNA to monitor treatment response and detect acquired resistance in patients with metastatic melanoma
2015
Adoptive cell transfer as personalized immunotherapy for human cancer
2015 StandoutScience
Timing and heterogeneity of mutations associated with drug resistance in metastatic cancers
2014
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Tumor cell heterogeneity.
1985
Noninvasive Identification and Monitoring of Cancer Mutations by Targeted Deep Sequencing of Plasma DNA
2012
Prospective Validation of Rapid Plasma Genotyping for the Detection ofEGFRandKRASMutations in Advanced Lung Cancer
2016
Tumor clone dynamics in lethal prostate cancer
2014
Circulating tumor cells: approaches to isolation and characterization
2011
Cancer: Evolution Within a Lifetime
2014
Limited heterogeneity of known driver gene mutations among the metastases of individual patients with pancreatic cancer
2017
Structures of the CCR5 N Terminus and of a Tyrosine-Sulfated Antibody with HIV-1 gp120 and CD4
2007 Science
Changes in mutational status during third‐line treatment for metastatic colorectal cancer—Results of consecutive measurement of cell free DNA, KRAS and BRAF in the plasma
2014
Solution NMR Characterizations of Oligomerization and Dynamics of Equine Infectious Anemia Virus Matrix Protein and Its Interaction with PIP2
2008
Human Immunodeficiency Virus Type 1 Matrix Inhibits and Confers Cooperativity on Gag Precursor-Membrane Interactions
2004
Circulating Cell-Free DNA Enables Noninvasive Diagnosis of Heart Transplant Rejection
2014
The future of immune checkpoint therapy
2015 StandoutScienceNobel
Metabolic reprogramming and cancer progression
2020 StandoutScience
Cancer Genome Landscapes
2013 StandoutScience
Mutation tracking in circulating tumor DNA predicts relapse in early breast cancer
2015
Lengthening and shortening of plasma DNA in hepatocellular carcinoma patients
2015
Determination of the Structures of Symmetric Protein Oligomers from NMR Chemical Shifts and Residual Dipolar Couplings
2011 StandoutNobel
Blood-Based Analyses of Cancer: Circulating Tumor Cells and Circulating Tumor DNA
2014
Liquid Biopsies: Genotyping Circulating Tumor DNA
2014 Standout
Analysis of ESR1 mutation in circulating tumor DNA demonstrates evolution during therapy for metastatic breast cancer
2015
Noninvasive detection of cancer-associated genome-wide hypomethylation and copy number aberrations by plasma DNA bisulfite sequencing
2013
Neoantigens in cancer immunotherapy
2015 StandoutScience
Mutation profiling of tumor DNA from plasma and tumor tissue of colorectal cancer patients with a novel, high-sensitivity multiplexed mutation detection platform
2014
Multiplex Picodroplet Digital PCR to Detect KRAS Mutations in Circulating DNA from the Plasma of Colorectal Cancer Patients
2013
The Long-Term Stability of the Human Gut Microbiota
2013 StandoutScience
Accurate sampling and deep sequencing of the HIV-1 protease gene using a Primer ID
2011
Evolutionary dynamics of cancer in response to targeted combination therapy
2013
Cancer Genome Scanning in Plasma: Detection of Tumor-Associated Copy Number Aberrations, Single-Nucleotide Variants, and Tumoral Heterogeneity by Massively Parallel Sequencing
2012
Cancer immunotherapy using checkpoint blockade
2018 StandoutScience
Elicitation of structure-specific antibodies by epitope scaffolds
2010 StandoutNobel
Noninvasive Prenatal Testing and Incidental Detection of Occult Maternal Malignancies
2015
Rapid Identification of Plasma DNA Samples with Increased ctDNA Levels by a Modified FAST-SeqS Approach
2015
Works of Isaac Kinde being referenced
Entropic switch regulates myristate exposure in the HIV-1 matrix protein
2003
Detection and quantification of rare mutations with massively parallel sequencing
2011
Association of the Autoimmune Disease Scleroderma with an Immunologic Response to Cancer
2013 Science
The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers
2012 Nature
Antiviral Inhibition of the HIV-1 Capsid Protein
2003
Circulating tumor DNA as an early marker of therapeutic response in patients with metastatic colorectal cancer
2015
FAST-SeqS: A Simple and Efficient Method for the Detection of Aneuploidy by Massively Parallel Sequencing
2012
Lavage of the Uterine Cavity for Molecular Detection of Müllerian Duct Carcinomas: A Proof-of-Concept Study
2015
Development of Personalized Tumor Biomarkers Using Massively Parallel Sequencing
2010
DETECTION OF CIRCULATING TUMOR DNA IN EARLY AND LATE STAGE HUMAN MALIGNANCIES
2014
Abstract 5606: Detection of circulating tumor DNA in early and late stage human malignancies
2014
Evaluation of DNA from the Papanicolaou Test to Detect Ovarian and Endometrial Cancers
2013
Detection of Chromosomal Alterations in the Circulation of Cancer Patients with Whole-Genome Sequencing
2012