Citation Impact
Citing Papers
CTLA-4 Control over Foxp3 + Regulatory T Cell Function
2008 StandoutScienceNobel
Differential use of endoplasmic reticulum membrane for phagocytosis in J774 macrophages
2005 StandoutNobel
Dishevelled 2 Recruits ß-Arrestin 2 to Mediate Wnt5A-Stimulated Endocytosis of Frizzled 4
2003 StandoutScienceNobel
Keeping G Proteins at Bay: A Complex Between G Protein-Coupled Receptor Kinase 2 and Gßγ
2003 StandoutScienceNobel
Programmed cell death 1 ligand 1 and tumor-infiltrating CD8 + T lymphocytes are prognostic factors of human ovarian cancer
2007 StandoutNobel
CTLA-4 up-regulation of lymphocyte function-associated antigen 1 adhesion and clustering as an alternate basis for coreceptor function
2005
Constitutive Clathrin-mediated Endocytosis of CTLA-4 Persists during T Cell Activation
2012
Confusing signals: Recent progress in CTLA-4 biology
2015
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Cargo Selection in Vesicular Transport: The Making and Breaking of a Coat
2002
Activation of Store-Operated Ca2+ Current in Xenopus Oocytes Requires SNAP-25 but Not a Diffusible Messenger
1999 StandoutNobel
The role of CD28 and cytotoxic T‐lymphocyte antigen‐4 (CTLA‐4) in regulatory T‐cell biology
2006
COPII-Coated Vesicle Formation Reconstituted with Purified Coat Proteins and Chemically Defined Liposomes
1998 StandoutNobel
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Linking cargo to vesicle formation: receptor tail interactions with coat proteins
1997
A Primer on Vesicle Budding
1999 StandoutNobel
Three ways to make a vesicle
2000
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
1997 StandoutNatureNobel
The reverse stop-signal model for CTLA4 function
2008
Comparison of the Intracellular Trafficking Itinerary of CTLA-4 Orthologues
2013
Signalling through the lipid products of phosphoinositide-3-OH kinase
1997 Nature
Coupling of Coat Assembly and Vesicle Budding to Packaging of Putative Cargo Receptors
1999 StandoutNobel
Multiple Cargo Binding Sites on the COPII Subunit Sec24p Ensure Capture of Diverse Membrane Proteins into Transport Vesicles
2003 StandoutNobel
Phosphatidylinositol-(4,5)-Bisphosphate Regulates Sorting Signal Recognition by the Clathrin-Associated Adaptor Complex AP2
2005
CTLA-4: new insights into its biological function and use in tumor immunotherapy
2002 StandoutNobel
Structure of clathrin coat with bound Hsc70 and auxilin: mechanism of Hsc70-facilitated disassembly
2009
The Interaction of β-Arrestin with the AP-2 Adaptor Is Required for the Clustering of β2-Adrenergic Receptor into Clathrin-coated Pits
2000
Identification of Sites Required for Down-regulation of Na+/H+ Exchanger NHE3 Activity by cAMP-dependent Protein Kinase
1997
The role of lipid signaling in constitutive membrane traffic
1997
Single-molecule analysis of a molecular disassemblase reveals the mechanism of Hsc70-driven clathrin uncoating
2011
Generation of Coated Intermediates of Clathrin-Mediated Endocytosis on Protein-Free Liposomes
1998
Clathrin functions in the absence of heterotetrameric adaptors and AP180-related proteins in yeast
1999
Clathrin Adaptor epsinR Is Required for Retrograde Sorting on Early Endosomal Membranes
2004
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
A di-leucine-based motif in the cytoplasmic tail of LIMP-II and tyrosinase mediates selective binding of AP-3
1998
Design of biologically active binary protein 2D materials
2021 StandoutNatureNobel
Association of Dishevelled with the Clathrin AP-2 Adaptor Is Required for Frizzled Endocytosis and Planar Cell Polarity Signaling
2007
The emerging role of CTLA4 as a cell-extrinsic regulator of T cell responses
2011
Adaptable adaptors for coated vesicles
2004
CTLA4 gene polymorphism and autoimmunity
2005
The Activity of the Epithelial Sodium Channel Is Regulated by Clathrin-mediated Endocytosis
1997
Sar1p N-Terminal Helix Initiates Membrane Curvature and Completes the Fission of a COPII Vesicle
2005 StandoutNobel
Restoring function in exhausted CD8 T cells during chronic viral infection
2005 StandoutNatureNobel
Molecular Architecture and Functional Model of the Endocytic AP2 Complex
2002
Adaptor-related proteins
2001
The Role of the Pleckstrin Homology Domain in Membrane Targeting and Activation of Phospholipase Cβ1
2000
CD28 and CTLA‐4 coreceptor expression and signal transduction
2009
Molecular mechanism and physiological functions of clathrin-mediated endocytosis
2011 Standout
Distinct Saturable Pathways for the Endocytosis of Different Tyrosine Motifs
1998 StandoutNobel
Mannose 6-phosphate receptors: new twists in the tale
2003
A Third Specificity‐Determining Site in μ2 Adaptin for Sequences Upstream of YxxΦ Sorting Motifs
2001
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
The β2-adrenergic receptor interacts with the Na+/H+-exchanger regulatory factor to control Na+/H+ exchange
1998 StandoutNatureNobel
Distinct Cellular Mechanisms Underlie Anti-CTLA-4 and Anti-PD-1 Checkpoint Blockade
2017 StandoutNobel
Sorting through the Cell Biology of Alzheimer's Disease: Intracellular Pathways to Pathogenesis
2006
Cytotoxic T Lymphocyte Antigen-4 Accumulation in the Immunological Synapse Is Regulated by TCR Signal Strength
2002 StandoutNobel
Lysosome-targeting chimaeras for degradation of extracellular proteins
2020 StandoutNatureNobel
Tyrosine Phosphatase SHP-2 Binding to CTLA-4: Absence of Direct YVKM/YFIP Motif Recognition
2000
Receptor Heterodimerization Modulates Endocytosis through Collaborative and Competitive Mechanisms
2019
Polarized trafficking and surface expression of the AQP4 water channel are coordinated by serial and regulated interactions with different clathrin-adaptor complexes
2001
Synaptotagmin Regulation of Coated Pit Assembly
2000 StandoutNobel
Endocytosis by Random Initiation and Stabilization of Clathrin-Coated Pits
2004
Intrinsically disordered proteins drive membrane curvature
2015
Slc15a4, AP-3, and Hermansky-Pudlak syndrome proteins are required for Toll-like receptor signaling in plasmacytoid dendritic cells
2010 StandoutNobel
The yeasts Rho1p and Pkc1p regulate the transport of chitin synthase III (Chs3p) from internal stores to the plasma membrane
2003 StandoutNobel
Coatomer, Arf1p, and nucleotide are required to bud coat protein complex I-coated vesicles from large synthetic liposomes
1998 StandoutNobel
B7x: A widely expressed B7 family member that inhibits T cell activation
2003 StandoutNobel
A single internalization signal from the di-leucine family is critical for constitutive endocytosis of the type II TGF-β receptor
2001
Clathrin-mediated endocytosis in AP-2–depleted cells
2003
Sorting of Mannose 6-Phosphate Receptors Mediated by the GGAs
2001 Science
Nonoverlapping roles of PD-1 and FoxP3 in maintaining immune tolerance in a novel autoimmune pancreatitis mouse model
2016 StandoutNobel
Interaction of CTLA-4 with AP50, a clathrin-coated pit adaptor protein
1997 StandoutNobel
AP-2 Recruitment to Synaptotagmin Stimulated by Tyrosine-Based Endocytic Motifs
1999 Science
Regulation of Cell Surface Expression of CTLA-4 by Secretion of CTLA-4-Containing Lysosomes Upon Activation of CD4+ T Cells
2000
A sequential mechanism for clathrin cage disassembly by 70-kDa heat-shock cognate protein (Hsc70) and auxilin
2011
Physiological [Ca2+]i level and pump-leak turnover in intact red cells measured using an incorporated Ca chelator
1982 StandoutNatureNobel
A vesicle carrier that mediates peroxisome protein traffic from the endoplasmic reticulum
2010 StandoutNobel
Transforming Growth Factor-β Receptors Interact with AP2 by Direct Binding to β2 Subunit
2002
Cell intrinsic mechanisms of T‐cell inhibition and application to cancer therapy
2008 StandoutNobel
Adaptors for Clathrin-Mediated Traffic
1999
Structural Analysis of CTLA-4 Function In Vivo
2000
Efficient Export of the Vesicular Stomatitis Virus G Protein from the Endoplasmic Reticulum Requires a Signal in the Cytoplasmic Tail That Includes Both Tyrosine-based and Di-acidic Motifs
2000
Tyrosine 201 of the cytoplasmic tail of CTLA ‐4 critically affects T regulatory cell suppressive function
2014
Focal Exocytosis of Vamp3-Containing Vesicles at Sites of Phagosome Formation
2000
Induction of autoimmune disease by deletion of CTLA-4 in mice in adulthood
2016 StandoutNobel
Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity
2000 StandoutNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
ADAPTORS FOR CLATHRIN COATS: Structure and Function
2004
Biologic activity of cytotoxic T lymphocyte-associated antigen 4 antibody blockade in previously vaccinated metastatic melanoma and ovarian carcinoma patients
2003 StandoutNobel
CLATHRIN-COATED VESICLE FORMATION AND PROTEIN SORTING: An Integrated Process
1997
B7-H3 and B7x are highly expressed in human prostate cancer and associated with disease spread and poor outcome
2007 StandoutNobel
UNC-11, aCaenorhabditis elegansAP180 Homologue, Regulates the Size and Protein Composition of Synaptic Vesicles
1999
CD28 Receptor Endocytosis Is Targeted by Mutations That Disrupt Phosphatidylinositol 3-Kinase Binding and Costimulation
1998
Endosomal sorting of readily releasable synaptic vesicles
2010 StandoutNobel
Amyloid precursor protein (APP) traffics from the cell surface via endosomes for amyloid β (Aβ) production in the trans -Golgi network
2012 StandoutNobel
Costimulatory Receptors in a Teleost Fish: Typical CD28, Elusive CTLA4
2006
PD-1 and CTLA-4 combination blockade expands infiltrating T cells and reduces regulatory T and myeloid cells within B16 melanoma tumors
2010 StandoutNobel
CTLA-4-Mediated Inhibition in Regulation of T Cell Responses: Mechanisms and Manipulation in Tumor Immunotherapy
2001 StandoutNobel
Treg-expressed CTLA-4 depletes CD80/CD86 by trogocytosis, releasing free PD-L1 on antigen-presenting cells
2021 StandoutNobel
Effects of 2-(4-Morpholinyl)-8-Phenyl-4H-1-Benzopyran-4-One on Synaptic Vesicle Cycling at the Frog Neuromuscular Junction
2002
Delayed onset of brain edema and mislocalization of aquaporin-4 in dystrophin-null transgenic mice
2002 StandoutNobel
A Structural Explanation for the Recognition of Tyrosine-Based Endocytotic Signals
1998 Science
gp25L/emp24/p24 Protein Family Members of the cis-Golgi Network Bind Both COP I and II Coatomer
1998
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 StandoutScienceNobel
Structure of the Sec23p/24p and Sec13p/31p complexes of COPII
2001 StandoutNobel
Involvement of PD-L1 on tumor cells in the escape from host immune system and tumor immunotherapy by PD-L1 blockade
2002 StandoutNobel
The determination of the free magnesium level in the human red blood cell by 31P NMR.
1978
ß-Arrestin 2 Mediates Endocytosis of Type III TGF-ß Receptor and Down-Regulation of Its Signaling
2003 StandoutScienceNobel
Differential control of human Treg and effector T cells in tumor immunity by Fc-engineered anti–CTLA-4 antibody
2018 StandoutNobel
Works of Iris Rapoport being referenced
Cytolytic T Lymphocyte-Associated Antigen-4 and the TCRζ/CD3 Complex, But Not CD28, Interact with Clathrin Adaptor Complexes AP-1 and AP-2
1999
A dileucine motif in HIV-1 Nef is essential for sorting into clathrin-coated pits and for downregulation of CD4
1998
Dileucine-based sorting signals bind to the beta chain of AP-1 at a site distinct and regulated differently from the tyrosine-based motif-binding site
1998
The μ2 Subunit of the Clathrin Adaptor AP‐2 Binds to FDNPVY and YppØ Sorting Signals at Distinct Sites
2002
Regulatory interactions in the recognition of endocytic sorting signals by AP-2 complexes
1997
Cytolytic T lymphocyte-associated antigen-4 and the TCR zeta/CD3 complex, but not CD28, interact with clathrin adaptor complexes AP-1 and AP-2.
1999
Sequence requirements for the recognition of tyrosine-based endocytic signals by clathrin AP-2 complexes.
1996
L1 endocytosis is controlled by a phosphorylation-dephosphorylation cycle stimulated by outside-in signaling by L1
2002
A Motif in the Clathrin Heavy Chain Required for the Hsc70/Auxilin Uncoating Reaction
2007
Response of the glycolysis of human erythrocytes to the transition from the oxygenated to the deoxygenated state at constant intracellular pH
1976