Citation Impact
Citing Papers
Confirmation of intersubunit connectivity and topology of designed protein complexes by native MS
2018 StandoutNobel
Directed evolution of the tryptophan synthase β-subunit for stand-alone function recapitulates allosteric activation
2015 StandoutNobel
Loss of conformational entropy in protein folding calculated using realistic ensembles and its implications for NMR-based calculations
2014 StandoutNobel
Innovative scattering analysis shows that hydrophobic disordered proteins are expanded in water
2017 StandoutScienceNobel
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
Origins of coevolution between residues distant in protein 3D structures
2017 StandoutNobel
Directed Evolution Mimics Allosteric Activation by Stepwise Tuning of the Conformational Ensemble
2018 StandoutNobel
Surface Sites for Engineering Allosteric Control in Proteins
2008 Science
Exploiting conformational dynamics to modulate the function of designed proteins
2023 StandoutNobel
Automated de novo prediction of native-like RNA tertiary structures
2007 StandoutNobel
Protein stability promotes evolvability
2006 StandoutNobel
Computational Stabilization of a Non‐Heme Iron Enzyme Enables Efficient Evolution of New Function
2024 StandoutNobel
Structural and Folding Dynamic Properties of the T70N Variant of Human Lysozyme
2003
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Origin of the sequence‐dependent polyproline II structure in unfolded peptides
2005
Direct measurement of protein binding energetics by isothermal titration calorimetry
2001
Atopic Dermatitis
2008 Standout
Dynamic personalities of proteins
2007 StandoutNature
Hot Spots for Allosteric Regulation on Protein Surfaces
2011
Reaching for high-hanging fruit in drug discovery at protein–protein interfaces
2007 StandoutNature
Principles of docking: An overview of search algorithms and a guide to scoring functions
2002
A Helix Propensity Scale Based on Experimental Studies of Peptides and Proteins
1998
The ensemble nature of allostery
2014 Nature
Substantial Energetic Improvement with Minimal Structural Perturbation in a High Affinity Mutant Antibody
2004
Heat Capacity Effects of Water Molecules and Ions at a Protein–DNA Interface
2004
Small‐Molecule Affinity Ligands for Protein Purification: Combined Computational Enrichment and Automated In‐line Screening of an Optically Encoded Library
2010 StandoutNobel
Phosfinder: a web server for the identification of phosphate-binding sites on protein structures
2011
Computational Enzyme Design
2013 StandoutNobel
Assessing the accuracy of physical models used in protein-folding simulations: quantitative evidence from long molecular dynamics simulations
2014
Structural Bases of Stability–function Tradeoffs in Enzymes
2002
Hot spots—A review of the protein–protein interface determinant amino‐acid residues
2007
Computational design of G Protein-Coupled Receptor allosteric signal transductions
2019
The role of dynamics in allosteric regulation
2003
Creating Small-Molecule-Dependent Switches to Modulate Biological Functions
2005
Engineering Allosteric Regulation into Biological Catalysts
2009
Anchor extension: a structure-guided approach to design cyclic peptides targeting enzyme active sites
2021 StandoutNobel
Solution Structure of Peptide Toxins That Block Mechanosensitive Ion Channels
2002
Predicting Drug‐Resistant Mutations of HIV Protease
2007 StandoutNobel
Surface-Induced Dissociation of Homotetramers with D2 Symmetry Yields their Assembly Pathways and Characterizes the Effect of Ligand Binding
2015
Small-molecule inhibitors of protein–protein interactions: progressing towards the dream
2004 Standout
Multiple diverse ligands binding at a single protein site: A matter of pre‐existing populations
2002
Immune surveillance in the skin: mechanisms and clinical consequences
2004
A “solvated rotamer” approach to modeling water‐mediated hydrogen bonds at protein–protein interfaces
2005 StandoutNobel
De novo design of bioactive protein switches
2019 StandoutNatureNobel
Photo-control of peptide helix content by an azobenzene cross-linker: steric interactions with underlying residues are not critical
2002
Energetics of Target Peptide Binding by Calmodulin Reveals Different Modes of Binding
2001
Allosteric regulation and catalysis emerge via a common route
2008
Spider toxins activate the capsaicin receptor to produce inflammatory pain
2006 StandoutNatureNobel
AutoDock4 and AutoDockTools4: Automated docking with selective receptor flexibility
2009 Standout
Ligand solvation in molecular docking
1999
Prediction of functionally important residues based solely on the computed energetics of protein structure 1 1Edited by B. Honig
2001
Binding Affinities of Host–Guest, Protein–Ligand, and Protein–Transition‐State Complexes
2003
Implications of protein flexibility for drug discovery
2003
Molecular Mechanisms of Amyloidosis
2003 Standout
Evolutionarily conserved networks of residues mediate allosteric communication in proteins
2002
Simple yet functional phosphate-loop proteins
2018 StandoutNobel
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
Structural and Energetic Basis of Allostery
2012
Functional Nucleic Acid Sensors
2009 Standout
Improving Protein Expression, Stability, and Function with ProteinMPNN
2024 StandoutNobel
Computer Simulation of Liquids
2017 Standout
Water as an Active Constituent in Cell Biology
2007 Standout
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Synthetic protein transduction domains: enhanced transduction potential in vitro and in vivo.
2001
Structure-based conformational preferences of amino acids
1999 StandoutNobel
Implicit Solvation Models: Equilibria, Structure, Spectra, and Dynamics
1999 Standout
Next Generation of Fluorine-Containing Pharmaceuticals, Compounds Currently in Phase II–III Clinical Trials of Major Pharmaceutical Companies: New Structural Trends and Therapeutic Areas
2016 Standout
Dynamic Combinatorial Chemistry
2006 Standout
Redox-Controlled Selective Docking in a [2]Catenane Host
2013 StandoutNobel
Bindungsaffinitäten von Wirt‐Gast‐, Protein‐Ligand‐ und Protein‐Übergangszustands‐Komplexen
2003
A direct comparison of helix propensity in proteins and peptides
1997
Classification of Intrinsically Disordered Regions and Proteins
2014 Standout
Reversible Photocontrol of Biological Systems by the Incorporation of Molecular Photoswitches
2013 StandoutNobel
Macromolecular Modeling with Rosetta
2008 StandoutNobel
Structure-based discovery of β 2 -adrenergic receptor ligands
2009 StandoutNobel
The structural distribution of cooperative interactions in proteins: Analysis of the native state ensemble
1998
Thermodynamic and Structural Effects of Conformational Constraints in Protein−Ligand Interactions. Entropic Paradoxy Associated with Ligand Preorganization
2009
Cancer Genome Landscapes
2013 StandoutScience
Agonism/antagonism switching in allosteric ensembles
2012
Electrostatic Basis for Enzyme Catalysis
2006 StandoutNobel
Peptide blockade of HIFα degradation modulates cellular metabolism and angiogenesis
2002 StandoutNobel
Chemistry and Biology Of Multicomponent Reactions
2012 Standout
Allosteric Modulation of Substrate Binding within a Tetracationic Molecular Receptor
2015 StandoutNobel
Structure and Mechanism of the Pepsin-Like Family of Aspartic Peptidases
2002
Improving Drug Candidates by Design: A Focus on Physicochemical Properties As a Means of Improving Compound Disposition and Safety
2011
Thermodynamics of Binding of a Low-Molecular-Weight CD4 Mimetic to HIV-1 gp120
2006
Folding of the C-terminal bacterial binding domain in statherin upon adsorption onto hydroxyapatite crystals
2006 StandoutNobel
Synthesis of bioactive protein hydrogels by genetically encoded SpyTag-SpyCatcher chemistry
2014 StandoutNobel
Redox Control of the Binding Modes of an Organic Receptor
2015 StandoutNobel
Works of Irene Luque being referenced
Structural parameterization of the binding enthalpy of small ligands
2002
Thermodynamic dissection of the binding energetics of KNI‐272, a potent HIV‐1 protease inhibitor
2000
[6] Structure-based prediction of binding affinities and molecular design of peptide ligands
1998
Structural stability of binding sites: Consequences for binding affinity and allosteric effects
2000
Structure-Based Thermodynamic Analysis of HIV-1 Protease Inhibitors
1997
Thermodynamic Basis of Resistance to HIV-1 Protease Inhibition: Calorimetric Analysis of the V82F/I84V Active Site Resistant Mutant
2000
Participation of T lymphocytes in cutaneous allergic reactions to drugs.
1998
Structure-based thermodynamic design of peptide ligands: Application to peptide inhibitors of the aspartic protease endothiapepsin
1998
Structure-based thermodynamic design of peptide ligands: application to peptide inhibitors of the aspartic protease endothiapepsin.
1998
Structural stability of binding sites: Consequences for binding affinity and allosteric effects
2000
The Linkage Between Protein Folding and Functional Cooperativity: Two Sides of the Same Coin?
2002
Identification and Characterization of Allophenylnorstatine-Based Inhibitors of Plasmepsin II, an Antimalarial Target
2002
The application of thermodynamic methods in drug design
2001
Structure-Based Thermodynamic Scale of α-Helix Propensities in Amino Acids
1996
Thermodynamic Characterization of the Folding Equilibrium of the Human Nedd4-WW4 Domain: At the Frontiers of Cooperative Folding
2009
Molecular Basis of Resistance to HIV-1 Protease Inhibition: A Plausible Hypothesis
1998