Irene Bolea

Hypoxia and intra-complex genetic suppressors rescue complex I mutants by a shared mechanism

Novel multi-target-directed ligands for Alzheimer's disease: Combining cholinesterase inhibitors and 5-HT 6 receptor antagonists. Design, synthesis and biological evaluation

N-Propargylpiperidines with naphthalene-2-carboxamide or naphthalene-2-sulfonamide moieties: Potential multifunctional anti-Alzheimer’s agents

The amyloid cascade hypothesis for Alzheimer's disease: an appraisal for the development of therapeutics

Trends in GPCR drug discovery: new agents, targets and indications

Cocoa Agronomy, Quality, Nutritional, and Health Aspects

NAD+ Regeneration Rescues Lifespan, but Not Ataxia, in a Mouse Model of Brain Mitochondrial Complex I Dysfunction

Pharmaceutical and medicinal significance of sulfur (SVI)-Containing motifs for drug discovery: A critical review

Anti-Aβ Drug Screening Platform Using Human iPS Cell-Derived Neurons for the Treatment of Alzheimer's Disease

Alzheimer's disease: clinical trials and drug development

Neurovascular pathways to neurodegeneration in Alzheimer's disease and other disorders

Synthesis and Evaluation of Multi-Target-Directed Ligands against Alzheimer’s Disease Based on the Fusion of Donepezil and Ebselen

Asymmetric Counter-Anion-Directed Aminomethylation: Synthesis of Chiral β-Amino Acids via Trapping of an Enol Intermediate

Development of Multifunctional Molecules as Potential Therapeutic Candidates for Alzheimer’s Disease, Parkinson’s Disease, and Amyotrophic Lateral Sclerosis in the Last Decade

Molecular Docking: Shifting Paradigms in Drug Discovery

Status, supply chain and processing of cocoa - A review

Catalytic Asymmetric Synthesis of Unprotected β²-Amino Acids

Reactive Oxygen Species (ROS)-Based Nanomedicine

Religious Orders Study and Rush Memory and Aging Project

A perspective on multi‐target drug discovery and design for complex diseases

Polypharmacology: Challenges and Opportunities in Drug Discovery

Relation of DASH- and Mediterranean-like dietary patterns to cognitive decline in older persons

LMN diet, rich in polyphenols and polyunsaturated fatty acids, improves mouse cognitive decline associated with aging and Alzheimer's disease

Multi-Target Directed Donepezil-Like Ligands for Alzheimer's Disease

Multipotent MAO and cholinesterase inhibitors for the treatment of Alzheimer's disease: Synthesis, pharmacological analysis and molecular modeling of heterocyclic substituted alkyl and cycloalkyl propargyl amine

Design, synthesis, pharmacological evaluation, QSAR analysis, molecular modeling and ADMET of novel donepezil–indolyl hybrids as multipotent cholinesterase/monoamine oxidase inhibitors for the potential treatment of Alzheimer's disease

Synthesis, Biological Evaluation, and Molecular Modeling of Donepezil and N-[(5-(Benzyloxy)-1-methyl-1H-indol-2-yl)methyl]-N-methylprop-2-yn-1-amine Hybrids as New Multipotent Cholinesterase/Monoamine Oxidase Inhibitors for the Treatment of Alzheimer’s Disease

P2‐238: Modulation of catecholaminergic and cholinergic neurons in mice fed with LMN diet, rich in polyphenols and polyunsaturated fatty acids

A Diet Enriched in Polyphenols and Polyunsaturated Fatty Acids, LMN Diet, Induces Neurogenesis in the Subventricular Zone and Hippocampus of Adult Mouse Brain

Defined neuronal populations drive fatal phenotype in a mouse model of Leigh syndrome