Citation Impact
Citing Papers
Targeting of Diacylglycerol Degradation to M1 Muscarinic Receptors by ß-Arrestins
2007 StandoutScienceNobel
Hallmarks of Cancer: The Next Generation
2011 Standout
Regulated import and degradation of a cytosolic protein in the yeast vacuole
1991 StandoutNatureNobel
From molecular to modular cell biology
1999 StandoutNatureNobel
Control of M-phase by maturation-promoting factor
1990
Ordering S phase and M phase in the cell cycle
1994 StandoutNobel
Activators and effectors of ras p21 proteins
1994
Hepatocyte growth factor/scatter factor—Met signaling in tumorigenicity and invasion/metastasis
1996
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
The complexity of Raf-1 regulation
1997
In VivoRegulation of Cytostatic Activity inXenopusMetaphase II-Arrested Oocytes
1997
MAP kinase kinase kinase, MAP kinase kinase and MAP kinase
1994
Differential Regulation of Raf-1, A-Raf, and B-Raf by Oncogenic Ras and Tyrosine Kinases
1997
Instability and decay of the primary structure of DNA
1993 StandoutNatureNobel
The protein kinase mos activates MAP kinase kinase in vitro and stimulates the MAP kinase pathway in mammalian somatic cells in vivo
1993 StandoutNobel
A novel p34cdc2-binding and activating protein that is necessary and sufficient to trigger G2/M progression in Xenopus oocytes
1999
The ubiquitin-proteasome proteolytic pathway
1994 StandoutNobel
The cyclin B2 component of MPF is a substrate for the c-mosxe proto-oncogene product
1990
Raf meets Ras: completing the framework of a signal transduction pathway
1994
Requirement for Ras in Raf activation is overcome by targeting Raf to the plasma membrane
1994 Nature
The CpG dinucleotide and human genetic disease
1988
Mitogen‐activated protein kinase (MAP kinase) activation in Xenopus oocytes: Roles of MPF and protein synthesis
1993
Real-time visualization of cell cycle-dependent changes in microtubule dynamics in cytoplasmic extracts
1990
Meiotic maturation in Xenopus requires polyadenylation of multiple mRNAs
1998
What does mos do in oocytes and somatic cells?
1997
The Hallmarks of Cancer
2000 Standout
Parthenogenetic activation of oocytes in c-mos-deficient mice
1994 Nature
Relationship of CDK-activating kinase and RNA polymerase II CTD kinase TFIIH/TFIIK
1994 StandoutNobel
Positional cloning of the mouse obese gene and its human homologue
1994 StandoutNature
Mechanism of Activation of the RAF-ERK Signaling Pathway by Oncogenic Mutations of B-RAF
2004 Standout
Interaction of 14-3-3 with Signaling Proteins Is Mediated by the Recognition of Phosphoserine
1996 Standout
Visualizing the mechanical activation of Src
2005 StandoutNatureNobel
A MAP kinase-dependent spindle assembly checkpoint in Xenopus egg extracts
1994
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
1993 StandoutNobel
Meiotic initiation by the mos protein in Xenopus
1992 Nature
Mos and the cell cycle: the molecular basis of the transformed phenotype
1993
Progesterone but not ras requires MPF for in vivo activation of MAPK and S6 KII: MAPK is an essential conexion point of both signaling pathways
1994
Immune Checkpoint Targeting in Cancer Therapy: Toward Combination Strategies with Curative Potential
2015 StandoutNobel
Weakly Polar Interactions In Proteins
1988
Regulation of the meiotic cell cycle in oocytes
2000
Crystal structure of the Hhal DNA methyltransferase complexed with S-adenosyl-l-methionine
1993 StandoutNobel
Activation of B-Raf kinase requires phosphorylation of the conserved residues Thr598 and Ser601
2000
Activation of Raf-1 by 14-3-3 proteins
1994 Nature
Cyclin is a component of maturation-promoting factor from Xenopus
1990 StandoutNobel
The Recruitment of Raf-1 to Membranes Is Mediated by Direct Interaction with Phosphatidic Acid and Is Independent of Association with Ras
2000
Serine and tyrosine phosphorylations cooperate in Raf-1, but not B-Raf activation
1999
Molecular themes in oncogenesis
1991 StandoutNobel
Cell-free apoptosis in Xenopus egg extracts: Inhibition by Bcl-2 and requirement for an organelle fraction enriched in mitochondria
1994
The mos proto‐oncogene product: Its role in oocyte maturation, metaphase arrest, and neoplastic transformation
1992
Polyadenylation of c-mos mRNA as a control point in Xenopus meiotic maturation
1995 Nature
Eph receptors and ephrins in cancer: bidirectional signalling and beyond
2010
Crystal Structure of the Hepatitis C Virus NS3 Protease Domain Complexed with a Synthetic NS4A Cofactor Peptide
1996 StandoutNobel
Xenopus oocytes and the biochemistry of cell division
1990
Lipid Phosphate Phosphatases 1 and 3 Are Localized in Distinct Lipid Rafts
2006
Multiple roles of eph receptors and ephrins in neural development
2001
Regulation by HIV Rev depends upon recognition of splice sites
1989 StandoutNobel
Purification and Characterization of REKS from Xenopus Eggs
1995
Do the poly(A) tail and 3′ untranslated region control mRNA translation?
1990
Disruption of c-mos causes parthenogenetic development of unfertilized mouse eggs
1994 StandoutNatureNobel
The receptor encoded by the human C‐MET oncogene is expressed in hepatocytes, epithelial cells and solid tumors
1991
Hsp90 is required for c-Mos activation and biphasic MAP kinase activation in Xenopus oocytes
2000
Crystallographic Analysis of the Recognition of a Nuclear Localization Signal by the Nuclear Import Factor Karyopherin α
1998 StandoutNobel
The c-mos proto-oncogene product is a cytostatic factor responsible for meiotic arrest in vertebrate eggs
1989 Nature
Xenopus oocyte maturation: new lessons from a good egg
1999
Independent inactivation of MPF and cytostatic factor (Mos) upon fertilization of Xenopus eggs
1991 StandoutNatureNobel
Speedy: a novel cell cycle regulator of the G2/M transition
1999
The critical role of the MAP kinase pathway in meiosis II in Xenopus oocytes is mediated by p90Rsk
2000
Insulin disrupts β-adrenergic signalling to protein kinase A in adipocytes
2005 StandoutNatureNobel
Activation of the Raf-1 kinase cascade by coumermycin-induced dimerization
1996 Nature
Specific proteolysis of the c-mos proto-oncogene product by calpain on fertilization of Xenopus eggs
1989 Nature
Positive and negative regulation of Raf kinase activity and function by phosphorylation
2001
Induction of metaphase arrest in cleaving Xenopus embryos by MAP kinase
1993 Science
Temporal order of S phase and mitosis in fission yeast is determined by the state of the p34cdc2-mitotic B cyclin complex
1994 StandoutNobel
Reversal of Raf-1 Activation by Purified and Membrane-Associated Protein Phosphatases
1995 Science
Requirement of mosXe Protein Kinase for Meiotic Maturation of Xenopus Oocytes Induced by a cdc2 Mutant Lacking Regulatory Phosphorylation Sites
1992
Requirement for the MAP kinase kinase/MAP kinase cascade in Xenopus oocyte maturation.
1994
Mechanisms of Xenopus oocyte maturation
1997
The met Proto-Oncogene Receptor and Lumen Formation
1992 Science
MPF Amplification inXenopusOocyte Extracts Depends on a Two-Step Activation of Cdc25 Phosphatase
1998
Regulation of Raf-1 kinase activity by the 14-3-3 family of proteins.
1995
Interaction of the Protein Kinase Raf-1 with 14-3-3 Proteins
1994 Science
Ability of the c- mos Product to Associate with and Phosphorylate Tubulin
1991 Science
Meaningful relationships: the regulation of the Ras/Raf/MEK/ERK pathway by protein interactions
2000
Analysis of the early embryonic cell cycles of Xenopus; regulation of cell cycle length by Xe-wee1 and Mos
1998
Regulation of Rous sarcoma virus RNA splicing and stability.
1988
Targeted mutations in the Caenorhabditis elegans POU homeo box gene ceh-18 cause defects in oocyte cell cycle arrest, gonad migration, and epidermal differentiation.
1994 StandoutNobel
Xenopus oocyte maturation does not require new cyclin synthesis.
1991 StandoutNobel
Effects of the v-mos oncogene on Xenopus development: meiotic induction in oocytes and mitotic arrest in cleaving embryos.
1990
Two Distinct Mechanisms Control the Accumulation of Cyclin B1 and Mos inXenopusOocytes in Response to Progesterone
1999
Memory Suppressor Genes: Inhibitory Constraints on the Storage of Long-Term Memory
1998 StandoutScienceNobel
Complementation of the Mitotic Activator, p80 cdc25 , by a Human Protein-tyrosine Phosphatase
1990 StandoutScienceNobel
Evidence that Mos protein may not act directly on cyclin.
1992
Cell Cycle Control and Cancer
1994 StandoutScienceNobel
Mos is required for MAP kinase activation and is involved in microtubule organization during meiotic maturation in the mouse
1996 StandoutNobel
The c-mos proto-oncogene protein kinase turns on and maintains the activity of MAP kinase, but not MPF, in cell-free extracts of Xenopus oocytes and eggs.
1993 StandoutNobel
Newly synthesized protein(s) must associate with p34cdc2 to activate MAP kinase and MPF during progesterone-induced maturation of Xenopus oocytes.
1995 StandoutNobel
Translational control by cytoplasmic polyadenylation of c-mos mRNA is necessary for oocyte maturation in the mouse.
1994
Biochemical and biological analysis of Mek1 phosphorylation site mutants.
1995
Suppression of DNA replication via Mos function during meiotic divisions in Xenopus oocytes.
1994
Cyclin B in Xenopus oocytes: implications for the mechanism of pre-MPF activation.
1991
Mos stimulates MAP kinase in Xenopus oocytes and activates a MAP kinase kinase in vitro.
1993
Meiosis-specific cell cycle regulation in maturing Xenopus oocytes
1994
On the synthesis and destruction of A- and B-type cyclins during oogenesis and meiotic maturation in Xenopus laevis.
1991 StandoutNobel
Degradation of Mos by the N-terminal proline (Pro2)-dependent ubiquitin pathway on fertilization of Xenopus eggs: possible significance of natural selection for Pro2 in Mos.
1993
Membrane Localization of Phosphatidylinositol 3-Kinase Is Sufficient To Activate Multiple Signal-Transducing Kinase Pathways
1996
CELLULAR FUNCTIONS REGULATED BY SRC FAMILY KINASES
1997 Standout
The induction of oocyte maturation: transmembrane signaling events and regulation of the cell cycle
1989
Identification of the Hepatocyte Growth Factor Receptor As the c- met Proto-Oncogene Product
1991 StandoutScience
Anatomy and Dynamics of a Supramolecular Membrane Protein Cluster
2007 StandoutScienceNobel
Mos Stimulates MAP Kinase in Xenopus Oocytes and Activates a MAP Kinase Kinase In Vitro
1993
Hepatocyte growth factor/scatter factor is an autocrine factor for human normal bronchial epithelial and lung carcinoma cells.
1993
The requirements for protein synthesis and degradation, and the control of destruction of cyclins A and B in the meiotic and mitotic cell cycles of the clam embryo.
1992 StandoutNobel
Raf-1 Protein Kinase Is Important for Progesterone-Induced Xenopus Oocyte Maturation and Acts Downstream of mos
1993
Regulation of Raf-1-Dependent Signaling during Early Xenopus Development
1995
Tumor Rejection After Direct Costimulation of CD8 + T Cells by B7-Transfected Melanoma Cells
1993 StandoutScienceNobel
The ksr-1 gene encodes a novel protein kinase involved in Ras-mediated signaling in C. elegans
1995 StandoutNobel
CpG-rich islands and the function of DNA methylation
1986 StandoutNature
Identification and early activation of a Xenopus laevis p70s6k following progesterone-induced meiotic maturation.
1992
Mos induces the in vitro activation of mitogen-activated protein kinases in lysates of frog oocytes and mammalian somatic cells.
1993
Mitogen-activated protein kinase kinase is required for the mos-induced metaphase arrest.
1994
Activation of p34cdc2 kinase by cyclin A.
1991
Raf-1 interacts with Fyn and Src in a non-phosphotyrosine-dependent manner
1994
New B-type cyclin synthesis is required between meiosis I and II duringXenopusoocyte maturation
2001 StandoutNobel
Scatter factor/hepatocyte growth factor and its receptor, the c-met tyrosine kinase, can mediate a signal exchange between mesenchyme and epithelia during mouse development.
1993
14-3-3 Is Not Essential for Raf-1 Function: Identification of Raf-1 Proteins That Are Biologically Activated in a 14-3-3- and Ras-Independent Manner
1995
Raf-1 protein kinase is important for progesterone-induced Xenopus oocyte maturation and acts downstream of mos.
1993
Cell cycle arrest and c-mos
1992 StandoutNatureNobel
The von Hippel-Lindau Tumor Suppressor Gene Inhibits Hepatocyte Growth Factor/Scatter Factor-Induced Invasion and Branching Morphogenesis in Renal Carcinoma Cells
1999 StandoutNobel
The Met Proto-Oncogene Mesenchymal to Epithelial Cell Conversion
1994 Science
Dissociation of MAP kinase activation and MPF activation in hormone-stimulated maturation of Xenopus oocytes
1999
Progression from meiosis I to meiosis II in Xenopus oocytes requires de novo translation of the mosxe protooncogene.
1991
The mutationally activated Met receptor mediates motility and metastasis
1998
The ‘second-codon rule’ and autophosphorylation govern the stability and activity of Mos during the meiotic cell cycle in Xenopus oocytes.
1992
Requirement of mosXe protein kinase for meiotic maturation of Xenopus oocytes induced by a cdc2 mutant lacking regulatory phosphorylation sites.
1992
Translocation of C. elegans CED-4 to Nuclear Membranes During Programmed Cell Death
2000 StandoutScienceNobel
Mammalian Mitogen-Activated Protein Kinase Signal Transduction Pathways Activated by Stress and Inflammation
2001 Standout
Invasiveness and metastasis of NIH 3T3 cells induced by Met-hepatocyte growth factor/scatter factor autocrine stimulation.
1994
Signal Transduction and Signal Modulation by Cell Adhesion Receptors: The Role of Integrins, Cadherins, Immunoglobulin-Cell Adhesion Molecules, and Selectins
1998
The 3'-untranslated regions of c-mos and cyclin mRNAs stimulate translation by regulating cytoplasmic polyadenylation.
1994 StandoutNobel
Tpl-2 acts in concert with Ras and Raf-1 to activate mitogen-activated protein kinase.
1994
SynCAM, a Synaptic Adhesion Molecule That Drives Synapse Assembly
2002 StandoutScienceNobel
p40MO15, a cdc2-related protein kinase involved in negative regulation of meiotic maturation of Xenopus oocytes.
1990
Works of Ira Daar being referenced
Structure, tissue-specific expression, and transforming activity of the mouse met protooncogene.
1990
Mos and Ras: Two Oncoproteins That Display M-phase Activity
1991
EphrinB1 controls cell–cell junctions through the Par polarity complex
2008
ephrinB1 signals from the cell surface to the nucleus by recruitment of STAT3
2007
Characterization of the functional gene and several processed pseudogenes in the human triosephosphate isomerase gene family.
1985
A characterization of cytostatic factor activity from Xenopus eggs and c-mos-transformed cells.
1991
Critical tyrosine residues regulate the enzymatic and biological activity of Raf-1 kinase.
1993
Human triose-phosphate isomerase deficiency: a single amino acid substitution results in a thermolabile enzyme.
1986
Protein kinase A acts at multiple points to inhibit Xenopus oocyte maturation.
1994
The ras Oncoprotein and M-Phase Activity
1991 Science
Fibroblast Growth Factor Receptor-Mediated Rescue of x-Ephrin B1-Induced Cell Dissociation in XenopusEmbryos
2000
Premature translation termination mediates triosephosphate isomerase mRNA degradation.
1988
The Product of the mos Proto-Oncogene as a Candidate "Initiator" for Oocyte Maturation
1989 Science
pp39mos Is Associated with p34cdc2 Kinase in c-mosxe-Transformed NIH 3T3 Cells
1992
The lipid phosphatase LPP3 regulates extra-embryonic vasculogenesis and axis patterning
2003
Inhibition of mos-induced oocyte maturation by protein kinase A.
1993
Requirement for Raf and MAP kinase function during the meiotic maturation of Xenopus oocytes
1993
Mutagenic analysis of functional domains of the mos proto-oncogene and identification of the sites important for MAPK activation and DNA binding.
1995
Premature Translation Termination Mediates Triosephosphate Isomerase mRNA Degradation
1988
Loss of cell adhesion in Xenopus laevis embryos mediated by the cytoplasmic domain of XLerk, an erythropoietin-producing hepatocellular ligand
1998
pp39mos is associated with p34cdc2 kinase in c-mosxe-transformed NIH 3T3 cells.
1992
mos gene transforming efficiencies correlate with oocyte maturation and cytostatic factor activities.
1991