Citation Impact
Citing Papers
Predominant Autoantibody Production by Early Human B Cell Precursors
2003 StandoutScience
Diversification, not use, of the immunoglobulin VH gene repertoire is restricted in DiGeorge syndrome.
1993 StandoutNobel
Rheumatoid Factor as a Potentiator of Anti–Citrullinated Protein Antibody–Mediated Inflammation in Rheumatoid Arthritis
2014
B cells in rheumatoid arthritis.
2000
The human immunoglobulin VH7 gene family consists of a small, polymorphic group of six to eight gene segments dispersed throughout the VH locus
1993
Linking class-switch recombination with somatic hypermutation
2001 StandoutNobel
The human immunoglobulin x locus. Characterization of the duplicated O regions
1991
Molecular structure of eight human autoreactive monoclonal antibodies
2001
By-passing immunization
1991 StandoutNobel
The human cord blood antibody repertoire. Frequent usage of the VH7 gene family
1992
Rheumatoid arthritis
2018 Standout
Rheumatoid arthritis
2016 Standout
Glycosylation and rheumatic disease
1999
Targeting by affinity–matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform
1997 StandoutNobel
Stromal Fibroblasts Present in Invasive Human Breast Carcinomas Promote Tumor Growth and Angiogenesis through Elevated SDF-1/CXCL12 Secretion
2005 Standout
Interleukin-10-Producing Plasmablasts Exert Regulatory Function in Autoimmune Inflammation
2014 StandoutNobel
Human Immunoglobulin Heavy-Chain Variable Region Genes: Organization, Polymorphism, and Expression
1991
Structure and physical map of 64 variable segments in the 3′ 0.8–megabase region of the human immunoglobulin heavy–chain locus
1993 StandoutNobel
Somatic mutation and memory
1993
Hepatitis C Virus, B-cell Proliferation and Lymphomas
2002
Delta-induced Notch Signaling Mediated by RBP-J Inhibits MyoD Expression and Myogenesis
1999 StandoutNobel
Why does inflammation persist: a dominant role for the stromal microenvironment?
2002
Methods for measurement of antibody/antigen affinity based on ELISA and RIA
1993
Efficacy of B-Cell–Targeted Therapy with Rituximab in Patients with Rheumatoid Arthritis
2004 Standout
Ectopic Lymphoid Structures Support Ongoing Production of Class-Switched Autoantibodies in Rheumatoid Synovium
2009
HAPPY mapping of a YAC reveals alternative haplotypes in the human immunoglobulin VHlocus
1993 StandoutNobel
The Pathogenesis of Rheumatoid Arthritis
2011 Standout
B-Cell Depletion with Rituximab in Relapsing–Remitting Multiple Sclerosis
2008 Standout
Antigen-driven clonal proliferation of B cells within the target tissue of an autoimmune disease. The salivary glands of patients with Sjögren's syndrome.
1998
Molecular basis of an autoantibody-associated restriction fragment length polymorphism that confers susceptibility to autoimmune diseases.
1991
Glycans in cancer and inflammation — potential for therapeutics and diagnostics
2005 StandoutNobel
Evolving concepts of rheumatoid arthritis
2003 StandoutNature
Organization of the Human Immunoglobulin Heavy-Chain Locus
1996
Complete sequence of the genes encoding the VH and VL regions of low- and high- affinity monoclonal lgM and lgA1 rheumatoid factors produced by CD5+ B cells from a rheumatoid arthritis patient
1991
The human immunoglobulin x locus. Characterization of the duplicated A regions
1992
Physical map of the 3′ region of the human immunoglobulin heavy chain locus: clustering of autoantibody-related variable segments in one haplotype.
1991 StandoutNobel
Combinatorial infection andin vivorecombination: a strategy for making large phage antibody repertoires
1993 StandoutNobel
Structure of human IgM rheumatoid factor Fab bound to its autoantigen IgG Fc reveals a novel topology of antibody—antigen interaction
1997
An Antibody Fragment from a Phage Display Library Competes for Ligand Binding to the Low Density Lipoprotein Receptor Family and Inhibits Rhinovirus Infection
1995 StandoutNobel
A human monoclonal IgA rheumatoid factor using the VkIV light chain gene
1992
Germline variable region gene segment derivation of human monoclonal anti-Rh(D) antibodies. Evidence for affinity maturation by somatic hypermutation and repertoire shift.
1992 StandoutNobel
By–Passing Immunization: Building High Affinity Human Antibodies by Chain Shuffling
1992 StandoutNobel
Human Antibody Fragments Specific for Human Blood Group Antigens from a Phage Display Library
1993 StandoutNobel
Retroviral vectors displaying functional antibody fragments
1993 StandoutNobel
Rheumatoid Factor Autoantibodies in Health and Diseasea
1997
Lymphoid neogenesis in chronic inflammatory diseases
2006
Role of B Cells in the Pathogenesis of Rheumatoid Arthritis
2001
The repertoire of human germline vH sequences reveals about fifty groups of VH segments with different hypervariable loops
1992 StandoutNobel
Structural repertoire of the human VH segments
1992 StandoutNobel
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
Chromatin–IgG complexes activate B cells by dual engagement of IgM and Toll-like receptors
2002 StandoutNature
Presence of a population of CD20+,CD38? B lymphocytes with defective proliferative responsiveness in the synovial compartment of patients with rheumatoid arthritis
2001
Guiding the Selection of Human Antibodies from Phage Display Repertoires to a Single Epitope of an Antigen
1994 StandoutNobel
Class Switch Recombination and Hypermutation Require Activation-Induced Cytidine Deaminase (AID), a Potential RNA Editing Enzyme
2000 StandoutNobel
In-cell PCR from mRNA: amplifying and linking the rearranged immunoglobulin heavy and light chain V-genes within single cells
1992 StandoutNobel
PATHOGENESIS OF RHEUMATOID ARTHRITIS
2001
Restricted use of fetal VH3 immunoglobulin genes by unselected B cells in the adult. Predominance of 56p1-like VH genes in common variable immunodeficiency.
1992
AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements
2007 StandoutNobel
Differential usage of an Ig heavy chain variable region gene by human B- cell tumors
1993
A map of the human immunoglobulin VH locus completed by analysis of the telomeric region of chromosome 14q
1994 StandoutNobel
Do self‐perpetuating B lymphocytes drive human autoimmune disease?
1999
A hallmark of active class switch recombination: Transcripts directed by I promoters on looped-out circular DNAs
2001 StandoutNobel
Idiotypic vaccination against human B-cell lymphoma. Rescue of variable region gene sequences from biopsy material for assembly as single-chain Fv personal vaccines
1994 StandoutNobel
Sequence analysis of the immunoglobulin antigen receptor of hepatitis C virus–associated non-Hodgkin lymphomas suggests that the malignant cells are derived from the rheumatoid factor–producing cells that occur mainly in type II cryoglobulinemia
2000
Clonal expansion of immunoglobulin M+CD27+ B cells in HCV-associated mixed cryoglobulinemia
2007 StandoutNobel
Molecular characterization of five human anti-human immunodeficiency virus type 1 antibody heavy chains reveals extensive somatic mutation typical of an antigen-driven immune response.
1991
Differentiation of B cells in the nonlymphoid tissue of the synovial membrane of patients with rheumatoid arthritis.
1996
Clonal B cells in patients with hepatitis C virus–associated mixed cryoglobulinemia contain an expanded anergic CD21low B-cell subset
2011 StandoutNobel
PD-1 and LAG-3 inhibitory co-receptors act synergistically to prevent autoimmunity in mice
2011 StandoutNobel
Distinct Effector Cytokine Profiles of Memory and Naive Human B Cell Subsets and Implication in Multiple Sclerosis
2007
Sustained improvement in rheumatoid arthritis following a protocol designed to deplete B lymphocytes
2001
Antibody fragments from a ‘single pot’ phage display library as immunochemical reagents.
1994 StandoutNobel
Human rheumatoid factor cross-idiotypes. IV. Studies on WA XId-positive IgM without rheumatoid factor activity provide evidence that the WA XId is not unique to rheumatoid factors and is distinct from the 17.109 and G6 XIds.
1993
Autoantigen-Specific B Cell Activation in FAS-Deficient Rheumatoid Factor Immunoglobulin Transgenic Mice
1999
Somatic Hypermutation, Clonal Diversity, and Preferential Expression of the VH 51p1/VL kv325 Immunoglobulin Gene Combination in Hepatitis C Virus–Associated Immunocytomas
1998
Activation and Differentiation of Autoreactive B-1 Cells by Interleukin 10 Induce Autoimmune Hemolytic Anemia in Fas-deficient Antierythrocyte Immunoglobulin Transgenic Mice
2002 StandoutNobel
Clonally-related Immunoglobulin VH Domains and Nonrandom Use of DH Gene Segments in Rheumatoid Arthritis Synovium
1998
Making Antibodies by Phage Display Technology
1994 StandoutNobel
Accumulation of Clonally Related B Lymphocytes in the Cerebrospinal Fluid of Multiple Sclerosis Patients
2000
Among B cell non-Hodgkin's lymphomas, MALT lymphomas express a unique antibody repertoire with frequent rheumatoid factor reactivity
2005
Alymphoplasia (aly)-Type Nuclear Factor κB–Inducing Kinase (Nik) Causes Defects in Secondary Lymphoid Tissue Chemokine Receptor Signaling and Homing of Peritoneal Cells to the Gut-Associated Lymphatic Tissue System
2000 StandoutNobel
B Lymphocytes Induce the Formation of Follicular Dendritic Cell Clusters in a Lymphotoxin α–dependent Fashion
1998
The Combinatorial Synthesis of Bicyclic Privileged Structures or Privileged Substructures
2003 Standout
Interaction between Synovial Inflammatory Tissue and Bone Marrow in Rheumatoid Arthritis
2005
Human rheumatoid B-1a (CD5+ B) cells make somatically hypermutated high affinity IgM rheumatoid factors.
1993
Distinct contribution of IL-6, TNF-α, IL-1, and IL-10 to T cell–mediated spontaneous autoimmune arthritis in mice
2004 StandoutNobel
The Complete Nucleotide Sequence of the Human Immunoglobulin Heavy Chain Variable Region Locus
1998 StandoutNobel
IgM and IgA Rheumatoid Factors Purified from Rheumatoid Arthritis Sera Boost the Fc Receptor– and Complement-Dependent Effector Functions of the Disease-Specific Anti–Citrullinated Protein Autoantibodies
2015
Molecular evolution of proteins on filamentous phage. Mimicking the strategy of the immune system.
1992 StandoutNobel
Clonal evolution of a follicular lymphoma: evidence for antigen selection.
1992
Works of Ingrid Randen being referenced
The Binding of Synovial Tissue‐Derived Human Monoclonal Immunoglobulin M Rheumatoid Factor to Immunoglobulin G Preparations of Differing Galactose Content
1994
The Identification of Germinal Centres and Follicular Dendritic Cell Networks in Rheumatoid Synovial Tissue
1995
V‐GENE Repertoire and Hypermutation of Rheumatoid Factors Produced in Rheumatoid Synovial Inflammation and Immunized Healthy Donorsa
1995
Rheumatoid factors isolated from patients with autoimmune disorders are derived from germline genes distinct from those encoding the Wa, Po, and Bla cross-reactive idiotypes.
1991
B Lymphocytes, B Cell Clones and Rheumatoid Factor Antibodies in Rheumatoid Inflammation
1988
Complementarity‐determining region 2 is implicated in the binding of staphylococcal protein A to human immunoglobulin VHIII variable regions
1993
Human monoclonal rheumatoid factors derived from the polyclonal repertoire of rheumatoid synovial tissue: Incidence of cross‐reactive idiotopes and expression of VH and Vϰ subgroups
1990
Synovial IgG rheumatoid factors show evidence of an antigen‐driven immune response and a shift in the V gene repertoire compared to IgM rheumatoid factors
1993
Variable region gene usage of human monoclonal rheumatoid factors derived from healthy donors following immunization
1994
The complete nucleotide sequences of the heavy chain variable regions of six monospecific rheumatoid factors derived from Epstein-Barr virus-transformed B cells isolated from the synovial tissue of patients with rheumatoid arthritis. Further evidence that some autoantibodies are unmutated copies of germ line genes.
1990
Three New Cross‐Reacting Idiotopes as Markers for the Products of Two Distinct Human VH3 Genes Expressed in the Early Repertoire
1994
Rheumatoid Factor V Genes from Patients with Rheumatoid Arthritis are Diverse and Show Evidence of an Antigen‐Driven Response
1992
Human Monoclonal Antibodies against Blood Group Antigens Preferentially Express a VH4‐21 Variable Region Gene‐Associated Epitope
1991
Clonally related IgM rheumatoid factors undergo affinity maturation in the rheumatoid synovial tissue
1992
Human monoclonal rheumatoid factors derived from the polyclonal repertoire of rheumatoid synovial tissue: production and characterization.
1989
Structural restriction in the heavy chain CDR3 of human rheumatoid factors.
1995
Mapping studies reveal unique epitopes on IgG recognized by rheumatoid arthritis-derived monoclonal rheumatoid factors.
1993
Probing of the rheumatoid factor (RF) V gene repertoire in rheumatoid arthritis (RA) by hybridoma clones.
1991
Control of autoantibody affinity by selection against amino acid replacements in the complementarity-determining regions.
1994
Nucleotide sequence analysis of the V regions of two IgM cold agglutinins. Evidence that the VH4-21 gene segment is responsible for the major cross-reactive idiotype.
1991