Citation Impact
Citing Papers
Histone demethylase KDM6A directly senses oxygen to control chromatin and cell fate
2019 StandoutScienceNobel
Hypoxia-Inducible Factor-2α Correlates to Distant Recurrence and Poor Outcome in Invasive Breast Cancer
2008
Hypoxia-inducible factors and RAB22A mediate formation of microvesicles that stimulate breast cancer invasion and metastasis
2014 StandoutNobel
Induction of ID2 Expression by Hypoxia-inducible Factor-1
2004
Hypoxia-inducible factor 2α (HIF-2α) heterozygous-null mice exhibit exaggerated carotid body sensitivity to hypoxia, breathing instability, and hypertension
2011 StandoutNobel
High-resolution genome-wide mapping of HIF-binding sites by ChIP-seq
2011 StandoutNobel
Involvement of oxygen-sensing pathways in physiologic and pathologic erythropoiesis
2009 StandoutNobel
HIF-2α regulates Oct-4: effects of hypoxia on stem cell function, embryonic development, and tumor growth
2006
Hallmarks of Cancer: The Next Generation
2011 Standout
Genome-wide Association of Hypoxia-inducible Factor (HIF)-1α and HIF-2α DNA Binding with Expression Profiling of Hypoxia-inducible Transcripts
2009 StandoutNobel
The role of hypoxia-inducible factors in tumorigenesis
2008
Hypoxia induces the breast cancer stem cell phenotype by HIF-dependent and ALKBH5-mediated m 6 A-demethylation of NANOG mRNA
2016 StandoutNobel
Passing the baton: the HIF switch
2012
TET1-Mediated Hydroxymethylation Facilitates Hypoxic Gene Induction in Neuroblastoma
2014
Hypoxia-Inducible Factors in Physiology and Medicine
2012 StandoutNobel
Biology of hypoxia-inducible factor-2α in development and disease
2008
Hypoxia Requires Notch Signaling to Maintain the Undifferentiated Cell State
2005
Tuning the Transcriptional Response to Hypoxia by Inhibiting Hypoxia-inducible Factor (HIF) Prolyl and Asparaginyl Hydroxylases
2016 StandoutNobel
Cancer Evolution and the Limits of Predictability in Precision Cancer Medicine
2016
Methylation-dependent regulation of HIF-1α stability restricts retinal and tumour angiogenesis
2016
Lymphoma-Specific Genetic Aberrations in Microvascular Endothelial Cells in B-Cell Lymphomas
2004
A view on drug resistance in cancer
2019 StandoutNature
The Histone Demethylases JMJD1A and JMJD2B Are Transcriptional Targets of Hypoxia-inducible Factor HIF
2008
The von Hippel–Lindau tumour suppressor protein: O2 sensing and cancer
2008 StandoutNobel
Molecular mechanisms of epithelial–mesenchymal transition
2014 Standout
Recruitment of HIF-1α and HIF-2α to common target genes is differentially regulated in neuroblastoma: HIF-2α promotes an aggressive phenotype
2006
Spermidine/Spermine-N1-Acetyltransferase 2 Is an Essential Component of the Ubiquitin Ligase Complex That Regulates Hypoxia-inducible Factor 1α
2007 StandoutNobel
Classification of chromosome segregation errors in cancer
2008
Clonal Heterogeneity and Tumor Evolution: Past, Present, and the Future
2017 Standout
Metastasis and stem cell pathways
2007
The bone marrow at the crossroads of blood and immunity
2011
The mini-driver model of polygenic cancer evolution
2015 StandoutNobel
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
Notch signaling in neuroblastoma
2004
Hippo Pathway in Organ Size Control, Tissue Homeostasis, and Cancer
2015 Standout
Hallmarks of cancer: Interactions with the tumor stroma
2010
Fumarate and Succinate Regulate Expression of Hypoxia-inducible Genes via TET Enzymes
2015 StandoutNobel
What a difference a hydroxyl makes: mutant IDH, (R)-2-hydroxyglutarate, and cancer
2013 StandoutNobel
Epigenetics in cancer
2009 Standout
Hypoxia-inducible factor–dependent breast cancer–mesenchymal stem cell bidirectional signaling promotes metastasis
2012 StandoutNobel
HIF-1 and hypoxic response: the plot thickens
2003
Four-and-a-Half LIM Domain Proteins Inhibit Transactivation by Hypoxia-inducible Factor 1
2012 StandoutNobel
Hypoxia inducible factor (HIF)‐2α is required for the development of the catecholaminergic phenotype of sympathoadrenal cells
2009
Requirement of the histone demethylase LSD1 in Snai1-mediated transcriptional repression during epithelial-mesenchymal transition
2010
Modulating Notch signaling by pathway-intrinsic and pathway-extrinsic mechanisms
2008
Hypoxic gene expression and metastasis
2004
Principles and Strategies for Developing Network Models in Cancer
2011
EMT: 2016
2016 Standout
Asparaginyl Hydroxylation of the Notch Ankyrin Repeat Domain by Factor Inhibiting Hypoxia-inducible Factor
2007 StandoutNobel
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
LSD1 demethylates HIF1α to inhibit hydroxylation and ubiquitin-mediated degradation in tumor angiogenesis
2017
Epithelioid Hemangioendothelioma: clinicopathologic, immunhistochemical, and molecular genetic analysis of 39 cases
2014
HIF-1 Regulates Cytochrome Oxidase Subunits to Optimize Efficiency of Respiration in Hypoxic Cells
2007 StandoutNobel
Opportunities in discovery and delivery of anticancer drugs targeting mitochondria and cancer cell metabolism☆
2009
Hsp70 and CHIP Selectively Mediate Ubiquitination and Degradation of Hypoxia-inducible Factor (HIF)-1α but Not HIF-2α
2009 StandoutNobel
Basic and Therapeutic Aspects of Angiogenesis
2011 Standout
The Canonical Notch Signaling Pathway: Unfolding the Activation Mechanism
2009 Standout
Oxygen Sensing, Homeostasis, and Disease
2011 StandoutNobel
Oxygen Sensing by Metazoans: The Central Role of the HIF Hydroxylase Pathway
2008 StandoutNobel
Multipolar Spindle Pole Coalescence Is a Major Source of Kinetochore Mis-Attachment and Chromosome Mis-Segregation in Cancer Cells
2009
Angiogenesis as a therapeutic target
2005 StandoutNature
Epigenetic Regulation of EMT: The Snail Story
2014
Spermidine/Spermine N1-Acetyltransferase-1 Binds to Hypoxia-inducible Factor-1α (HIF-1α) and RACK1 and Promotes Ubiquitination and Degradation of HIF-1α
2007 StandoutNobel
The paradox of arsenic: molecular mechanisms of cell transformation and chemotherapeutic effects
2002
Histone lysine methylation and demethylation pathways in cancer
2010
Chaperone-mediated Autophagy Targets Hypoxia-inducible Factor-1α (HIF-1α) for Lysosomal Degradation
2013 StandoutNobel
Clues from cell metabolism
2010 StandoutNatureNobel
HIF-1α is required for development of the sympathetic nervous system
2019 StandoutNobel
Life with Oxygen
2007 StandoutScienceNobel
Cancer stem cells from colorectal cancer-derived cell lines
2010
Digoxin and other cardiac glycosides inhibit HIF-1α synthesis and block tumor growth
2008 StandoutNobel
Reversal of Histone Methylation: Biochemical and Molecular Mechanisms of Histone Demethylases
2010
Posttranslational hydroxylation of ankyrin repeats in IκB proteins by the hypoxia-inducible factor (HIF) asparaginyl hydroxylase, factor inhibiting HIF (FIH)
2006 StandoutNobel
Hypoxia-Inducible Factor-1-Independent Regulation of Vascular Endothelial Growth Factor by Hypoxia in Colon Cancer
2004
Adaptive and Maladaptive Cardiorespiratory Responses to Continuous and Intermittent Hypoxia Mediated by Hypoxia-Inducible Factors 1 and 2
2012 StandoutNobel
Organogenesis in a dish: Modeling development and disease using organoid technologies
2014 StandoutScience
Transcriptional regulation of vascular endothelial cell responses to hypoxia by HIF-1
2004 StandoutNobel
Spermidine in health and disease
2018 StandoutScience
The Ecology of Arsenic
2003 StandoutScience
Endothelial Hypoxia-Inducible Factor-2α Is Required for the Maintenance of Airway Microvasculature
2019 StandoutNobel
Methylation of hypoxia-inducible factor (HIF)-1α by G9a/GLP inhibits HIF-1 transcriptional activity and cell migration
2018 StandoutNobel
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Hypoxia-inducible factor-dependent signaling between triple-negative breast cancer cells and mesenchymal stem cells promotes macrophage recruitment
2014 StandoutNobel
Hypoxia and HIF1α Repress the Differentiative Effects of BMPs in High-Grade Glioma
2008
Histone deacetylase 10 promotes autophagy-mediated cell survival
2013
Distinct breast cancer stem/progenitor cell populations require either HIF1α or loss of PHD3 to expand under hypoxic conditions
2015
Hypoxia: a key player in antitumor immune response. A Review in the Theme: Cellular Responses to Hypoxia
2015
Works of Ingrid Øra being referenced
Lysine-Specific Demethylase 1 Is Strongly Expressed in Poorly Differentiated Neuroblastoma: Implications for Therapy
2009
The basic helix-loop-helix transcription factor dHAND, a marker gene for the developing human sympathetic nervous system, is expressed in both high- and low-stage neuroblastomas.
1999
High levels of HIF‐2α highlight an immature neural crest‐like neuroblastoma cell cohort located in a perivascular niche
2008
NF1 Is a Tumor Suppressor in Neuroblastoma that Determines Retinoic Acid Response and Disease Outcome
2010
Hypoxia-induced dedifferentiation in neuroblastoma cells
2003
Copy number defects of G1‐Cell cycle genes in neuroblastoma are frequent and correlate with high expression of E2F target genes and a poor prognosis
2011
Hypoxia alters gene expression in human neuroblastoma cells toward an immature and neural crest-like phenotype
2002
A novel SERPINE1–FOSB fusion gene results in transcriptional up‐regulation of FOSB in pseudomyogenic haemangioendothelioma
2013
Generation of trisomies in cancer cells by multipolar mitosis and incomplete cytokinesis
2010
Arsenic Trioxide Inhibits Neuroblastoma Growth in Vivo and Promotes Apoptotic Cell Death in Vitro
2000
Defective Chromosome Segregation and Telomere Dysfunction in Aggressive Wilms' Tumors
2007