Citation Impact
Citing Papers
Circulating Breast Tumor Cells Exhibit Dynamic Changes in Epithelial and Mesenchymal Composition
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Tumor Cells Circulate in the Peripheral Blood of All Major Carcinomas but not in Healthy Subjects or Patients With Nonmalignant Diseases
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Suppression of bone resorption by madindoline A, a novel nonpeptide antagonist to gp130
2002 StandoutNobel
Vigorous Premalignancy-specific Effector T Cell Response in the Bone Marrow of Patients with Monoclonal Gammopathy
2003
ERalpha-status of disseminated tumour cells in bone marrow of primary breast cancer patients
2008
Hallmarks of Cancer: The Next Generation
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Detection of breast cancer cells in the peripheral blood is positively correlated with estrogen‐receptor status and predicts for poor prognosis
2003
American Society of Clinical Oncology 2007 Update of Recommendations for the Use of Tumor Markers in Breast Cancer
2007 Standout
Her2 expression on disseminated tumor cells from bone marrow of breast cancer patients.
2005
Adjuvant bisphosphonate treatment in early breast cancer: meta-analyses of individual patient data from randomised trials
2015
Endogenous human microRNAs that suppress breast cancer metastasis
2008 StandoutNature
Dissecting the metastatic cascade
2004
Patterns of metastatic breast carcinoma: influence of tumour histological grade
2004
Cellular and molecular basis of preferential metastasis of breast cancer to bone
2000
TGF-β signaling blockade inhibits PTHrP secretion by breast cancer cells and bone metastases development
1999
Fracture healing in the elderly patient
2006
Genes that mediate breast cancer metastasis to the brain
2009 StandoutNature
Stemming bone loss by suppressing apoptosis
1999
Bone marrow micrometastases in 109 breast cancer patients: Correlations with clinical and pathological features and prognosis
1997
Prognostic Significance of Occult Bone Marrow Micrometastases of Breast Cancer Detected by Quantitative Polymerase Chain Reaction for Cytokeratin 19 mRNA
2000
Mammaglobin Gene Expression: A Superior Marker of Breast Cancer Cells in Peripheral Blood in Comparison to Epidermal-Growth-Factor Receptor and Cytokeratin-19
2000
Detection of Breast Cancer micrometastases in peripheral blood using immunomagnetic separation and immunocytochemistry
2001
Cancer to bone: a fatal attraction
2011 Standout
Minimal Residual Disease in Bone Marrow and Peripheral Blood of Patients with Metastatic Breast Cancer
2003
The Cathepsin K Inhibitor Odanacatib Suppresses Bone Resorption in Women With Breast Cancer and Established Bone Metastases: Results of a 4-Week, Double-Blind, Randomized, Controlled Trial
2010
Mediators of vascular remodelling co-opted for sequential steps in lung metastasis
2007 Nature
Active immunization against cancer with dendritic cells: The near future
2001 StandoutNobel
Peripheral blood circulating cytokeratin-19 mRNA-positive cells after the completion of adjuvant chemotherapy in patients with operable breast cancer
2003
REVIEW: Detection of circulating breast cancer cells by reverse transcriptase polymerase chain reaction (RT-PCR)
2000
Use of radionuclides for the palliation of bone metastases
2000
Dissemination and growth of cancer cells in metastatic sites
2002 Standout
A real-time quantitative reverse transcriptase polymerase chain reaction (RT–PCR) to detect breast carcinoma cells in peripheral blood
2001
TGF-β1–induced migration of bone mesenchymal stem cells couples bone resorption with formation
2009 Standout
Imaging transforming growth factor-β signaling dynamics and therapeutic response in breast cancer bone metastasis
2009
DETECTION OF DISSEMINATED TUMOR CELLS IN PERIPHERAL BLOOD
2005
Regulation of the gp80 and gp130 subunits of the IL-6 receptor by sex steroids in the murine bone marrow.
1997
Evaluation of breast tumour cell contamination in the bone marrow and leukapheresis collections by RT‐PCR for cytokeratin‐19 mRNA
1998
Isolation of rare circulating tumour cells in cancer patients by microchip technology
2007 StandoutNature
Bone metastases from breast carcinoma: histopathological – radiological correlations and prognostic features
2003
Prognostic relevance of urokinase plasminogen activator detection in micrometastatic cells in the bone marrow of patients with primary breast cancer
1997
Models, mechanisms and clinical evidence for cancer dormancy
2007
Antigen-specific Tregs control T cell responses against a limited repertoire of tumor antigens in patients with colorectal carcinoma
2009
Cytokine production in the bone marrow microenvironment: failure to demonstrate estrogen regulation in early postmenopausal women.
1996
Significance, detection and markers of disseminated breast cancer cells
2006
Circulating tumour cells in breast cancer
2004
A concept for the standardized detection of disseminated tumor cells in bone marrow from patients with primary breast cancer and its clinical implementation
2006
Prognostic value of bone marrow biopsy in operable breast cancer patients at the time of initial diagnosis: Results of a 20-year median follow-up
1998
Tumour invasion and metastasis initiated by microRNA-10b in breast cancer
2007 StandoutNature
PD-1 and PD-L1 Immune Checkpoint Blockade to Treat Breast Cancer
2016 Standout
Bone Marrow, Cytokines, and Bone Remodeling — Emerging Insights into the Pathophysiology of Osteoporosis
1995
OPGL is a key regulator of osteoclastogenesis, lymphocyte development and lymph-node organogenesis
1999 StandoutNature
Principles of adoptive T cell cancer therapy
2007
Molecular Determinants of Occult Metastatic Tumor Cells in Bone Marrow
2001
Cytokines, bone remodeling, and estrogen deficiency: a 1998 update
1998
Tumour heterogeneity and cancer cell plasticity
2013 StandoutNature
Evaluation of Factors Related to Late Recurrence - Later than 10 Years after the Initial Treatment - in Primary Breast Cancer
2013 Standout
Cytokeratin-Positive Cells in the Bone Marrow and Survival of Patients with Stage I, II, or III Breast Cancer
2000
Cancer vaccines: between the idea and the reality
2003
Osteoclast differentiation and activation
2003 StandoutNature
Interleukin‐6 maintains bone marrow‐derived mesenchymal stem cell stemness by an ERK1/2‐dependent mechanism
2009
Prognostic relevance of cathepsin D detection in micrometastatic cells in the bone marrow of patients with primary breast cancer
1998
The evolving role of bisphosphonates
2001
The causes and consequences of genetic heterogeneity in cancer evolution
2013 StandoutNature
Transfection of MDA-MB-231 human breast carcinoma cells with bone sialoprotein (BSP) stimulates migration and invasion in vitro and growth of primary and secondary tumors in nude mice
2004
Coupling of angiogenesis and osteogenesis by a specific vessel subtype in bone
2014 StandoutNature
Solitary cancer cells as a possible source of tumour dormancy?
2001
Cancer immunotherapy comes of age
2011 StandoutNature
Ineffectiveness of Doxorubicin Treatment on Solitary Dormant Mammary Carcinoma Cells or Late-developing Metastases
2003
Metastasis to bone: causes, consequences and therapeutic opportunities
2002 Standout
Sensitive detection of circulating breast cancer cells by reverse-transcriptase polymerase chain reaction of maspin gene
1996
Telomere length in leukocytes correlates with bone mineral density and is shorter in women with osteoporosis
2007
Dormancy in breast cancer
2012
Bone marrow micrometastases in breast cancer patients
1999
Future directions of bone-targeted therapy for metastatic breast cancer
2010
Osteopontin: An Effector and an Effect of Tumor Metastasis
2010
Glypican-1 identifies cancer exosomes and detects early pancreatic cancer
2015 StandoutNature
Bone metastasis: the importance of the neighbourhood
2016
Outcome of primary-breast-cancer patients with micrometastases: a long-term follow-up study
1999
The role of senescent cells in ageing
2014 StandoutNature
Clonal evolution in cancer
2012 StandoutNature
The Hallmarks of Aging
2013 Standout
Osteogenesis and Bone-Marrow-Derived Cells
2001
Tumour cell detection in the bone marrow of breast cancer patients at primary therapy: results of a 3-year median follow-up
1994
Detection, clinical relevance and specific biological properties of disseminating tumour cells
2008
Enrichment methods to detect bone marrow micrometastases in breast carcinoma patients: clinical relevance
2004
Immunocytochemical detection of isolated epithelial cells in bone marrow: non-specific staining and contribution by plasma cells directly reactive to alkaline phosphatase
1998
Metastatic colonization by circulating tumour cells
2016 StandoutNature
Missed micrometastatic disease in breast cancer
2004
Estrogen’s bone-protective effects may involve differential IL-1 receptor regulation in human osteoclast-like cells
1999
Genes that mediate breast cancer metastasis to lung
2005 StandoutNature
Comprehensive Integration of Single-Cell Data
2019 Standout
The Role of IL‐6 Type Cytokines and Their Receptors in Boneaa
1998
Novel approaches to target the microenvironment of bone metastasis
2021
CCL2 recruits inflammatory monocytes to facilitate breast-tumour metastasis
2011 StandoutNature
Breast cancer metastasis: markers and models
2005 Standout
Small integrin-binding ligand N-linked glycoproteins (SIBLINGs): multifunctional proteins in cancer
2008
Detection of cytokeratin-positive cells in the bone marrow of breast cancer patients undergoing adjuvant therapy
2005
Reliable and Sensitive Identification of Occult Tumor Cells Using the Improved Rare Event Imaging System
2004
ASCO 2006 Update of Recommendations for the Use of Tumor Markers in Gastrointestinal Cancer
2006
Genomic Profiling of Viable and Proliferative Micrometastatic Cells from Early-Stage Breast Cancer Patients
2004
Detection of Isolated Tumor Cells in Bone Marrow Is an Independent Prognostic Factor in Breast Cancer
2003
Most Early Disseminated Cancer Cells Detected in Bone Marrow of Breast Cancer Patients Have a Putative Breast Cancer Stem Cell Phenotype
2006
Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications
2001 Standout
Lack of Effect of Adjuvant Chemotherapy on the Elimination of Single Dormant Tumor Cells in Bone Marrow of High-Risk Breast Cancer Patients
2000
Telomere length is paternally inherited and is associated with parental lifespan
2007 StandoutNobel
In Vitro Secretion of Cytokines by Human Bone Marrow: Effects of Age and Estrogen Status1
1998
Reporting Recommendations for Tumor Marker Prognostic Studies
2005
The bisphosphonate ibandronate promotes apoptosis in MDA-MB-231 human breast cancer cells in bone metastases.
2001
Advancing Treatment for Metastatic Bone Cancer: Consensus Recommendations from the Second Cambridge Conference
2008
Bone Resorption by Osteoclasts
2000 StandoutScience
A Perspective on Cancer Cell Metastasis
2011 StandoutScience
Simultaneous Immunohistochemical Detection of Tumor Cells in Lymph Nodes and Bone Marrow Aspirates in Breast Cancer and Its Correlation With Other Prognostic Factors
2001
Micrometastatic Disease and Metastatic Outgrowth: Clinical Issues and Experimental Approaches
2009
The Effect of a Single Dose of Osteoprotegerin in Postmenopausal Women
2001
Human memory T cells from the bone marrow are resting and maintain long-lasting systemic memory
2014
Cancer Immunoediting: Integrating Immunity’s Roles in Cancer Suppression and Promotion
2011 StandoutScience
Bisphosphonate treatment inhibits the growth of prostate cancer cells.
2001
A rare-cell detector for cancer
2004
Hypoxia-inducible factor 1-dependent expression of adenosine receptor 2B promotes breast cancer stem cell enrichment
2018 StandoutNobel
Tumor Cell Interactions With the Microvasculature
2001
Time independence of the prognostic impact of tumor cell detection in the bone marrow of primary breast cancer patients.
2001
Metastatic bone disease: clinical features, pathophysiology and treatment strategies
2001 Standout
Molecular Detection of Cytokeratin-19–Positive Cells in the Peripheral Blood of Patients With Operable Breast Cancer: Evaluation of Their Prognostic Significance
2002
Effect of zoledronate on persisting isolated tumour cells in patients with early breast cancer.
2010
Total Synthesis of (+)-Madindoline A and (−)-Madindoline B, Potent, Selective Inhibitors of Interleukin 6. Determination of the Relative and Absolute Configurations
2000 StandoutNobel
Immune-mediated dormancy: an equilibrium with cancer
2008
Electrochemiluminescence (ECL)
2004 Standout
Chemotherapy induces enrichment of CD47 + /CD73 + /PDL1 + immune evasive triple-negative breast cancer cells
2018 StandoutNobel
Birth and Death of Bone Cells: Basic Regulatory Mechanisms and Implications for the Pathogenesis and Treatment of Osteoporosis*
2000 Standout
Clinical Significance of Immunocytochemical Detection of Tumor Cells Using Digital Microscopy in Peripheral Blood and Bone Marrow of Breast Cancer Patients
2004
Avoiding horror autotoxicus: The importance of dendritic cells in peripheral T cell tolerance
2002 StandoutNobel
Predictive and Prognostic Value of Peripheral Blood Cytokeratin-19 mRNA-Positive Cells Detected by Real-Time Polymerase Chain Reaction in Node-Negative Breast Cancer Patients
2006
HTLV-1 Tax transgenic mice develop spontaneous osteolytic bone metastases prevented by osteoclast inhibition
2005
Anti-CCR4 mAb selectively depletes effector-type FoxP3+CD4+regulatory T cells, evoking antitumor immune responses in humans
2013 StandoutNobel
BRCA1-IRIS promotes human tumor progression through PTEN blockade and HIF-1α activation
2018 StandoutNobel
Marrow Stromal Cells as Stem Cells for Nonhematopoietic Tissues
1997 StandoutScience
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Detection of Circulating Tumor Cells by Reverse Transcriptase Polymerase Chain Reaction of Maspin in Patients With Breast Cancer Undergoing Conventional-Dose Chemotherapy
2000
Systematic Review of Microsatellite Instability and Colorectal Cancer Prognosis
2005
Bisphosphonates inhibit breast and prostate carcinoma cell invasion, an early event in the formation of bone metastases.
2000
Adjuvant Clodronate Treatment Does Not Reduce the Frequency of Skeletal Metastases in Node-Positive Breast Cancer Patients: 5-Year Results of a Randomized Controlled Trial
2001
Immunotherapy: Bewitched, Bothered, and Bewildered No More
2004 StandoutScienceNobel
IL-6 as a drug discovery target
1998
HIF-1 regulates CD47 expression in breast cancer cells to promote evasion of phagocytosis and maintenance of cancer stem cells
2015 StandoutNobel
Comparative Analysis of Micrometastasis to the Bone Marrow and Lymph Nodes of Node-Negative Breast Cancer Patients Receiving No Adjuvant Therapy
2001
Rational Design of Bisphosphonate Lipid-like Materials for mRNA Delivery to the Bone Microenvironment
2022 StandoutNobel
Isolated Tumor Cells in Bone Marrow Three Years after Diagnosis in Disease-Free Breast Cancer Patients Predict Unfavorable Clinical Outcome1
2004
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
Detection of Breast Cancer Cells in the Bone Marrow or Peripheral Blood: Methods and Prognostic Significance
2000
A Mouse Model of Human Breast Cancer Metastasis to Human Bone
2005
Circulating Tumor Cells and Bone Marrow Micrometastasis
2008
The Effects of Androgen Deficiency on Murine Bone Remodeling and Bone Mineral Density Are Mediated via Cells of the Osteoblastic Lineage*
1997
Response of Circulating Tumor Cells to Systemic Therapy in Patients With Metastatic Breast Cancer: Comparison of Quantitative Polymerase Chain Reaction and Immunocytochemical Techniques
2000
Detection and clinical implications of early systemic tumor cell dissemination in breast cancer.
2003
Detection of occult metastatic breast cancer cells in blood by a multimolecular marker assay: correlation with clinical stage of disease.
2001
Works of Ingo Diel being referenced
Therapy of human tumors in NOD/SCID mice with patient-derived reactivated memory T cells from bone marrow
2001
Adjuvant oral clodronate improves the overall survival of primary breast cancer patients with micrometastases to the bone marrow—a long-term follow-up
2008
Serum bone sialoprotein as a marker of tumour burden and neoplastic bone involvement and as a prognostic factor in multiple myeloma
2001
Concentrations of insulin-like growth factor (IGF)-I, -II, and IGF binding protein-4, and -5 in human bone cell conditioned medium do not change with age
2000
Age-associated changes in the stimulatory effect of transforming growth factor beta on human osteogenic colony formation
1999
Expression of Interleukin-6 (IL-6) and IL-6 receptor mRNA in human bone samples from pre- and postmenopausal women
2002
Detection of tumor cells in bone marrow of patients with primary breast cancer: a prognostic factor for distant metastasis.
1992
Treatment of Metastatic Bone Disease in Breast Cancer: Bisphosphonates
2000
Bisphosphonates and the prevention of metastasis
2000
Reduction in New Metastases in Breast Cancer with Adjuvant Clodronate Treatment
1998
Intravenous ibandronate reduces the incidence of skeletal complications in patients with breast cancer and bone metastases
2003
Analysis of sensitivity and specificity of cytokeratin 19 reverse transcriptase/polymerase chain reaction for detection of occult breast cancer in bone marrow and leukapheresis products
1999
Prognostic factors for skeletal relapse in breast cancer
2001
Current use of bisphosphonates in oncology. International Bone and Cancer Study Group.
1998
Prognostische Bedeutung des Tumorzellnachweises im Knochenmark von Patientinnen mit Mammakarzinom
1990
Results of iliac crest biopsies taken from 1465 patients with primary breast cancer
1998
Metastatic breast cancer: clinical course, prognosis and therapy related to the first site of metastasis
2000
Oral ibandronate reduces the risk of skeletal complications in breast cancer patients with metastatic bone disease: results from two randomised, placebo-controlled phase III studies
2004
Standardization of the immunocytochemical detection of cancer cells in BM and blood: I. establishment of objective criteria for the evaluation of immunostained cells
1999
Micrometastatic Breast Cancer Cells in Bone Marrow at Primary Surgery: Prognostic Value in Comparison With Nodal Status
1996
Prognostic Value of Disseminated Tumor Cells in the Bone Marrow of Patients with Operable Primary Breast Cancer: A Long-term Follow-up Study
2012
Bone marrow and lymph node assessment for minimal residual disease in patients with breast cancer
2000
Concentration of Transforming Growth Factor Beta in Human Bone Tissue: Relationship to Age, Menopause, Bone Turnover, and Bone Volume
1998
Influence of adjuvant hormone therapy and chemotherapy on the immune system analysed in the bone marrow of patients with breast cancer.
2003
Enrichment of memory T cells and other profound immunological changes in the bone marrow from untreated breast cancer patients
2001
Bone marrow staging for breast cancer: Is it better than axillary node dissection?
2001
Micrometastatic tumor cells in bone marrow versus nodal status in breast cancer—Impact on prognosis in patients with primary breast cancer
1995
Increased cytokine secretion by human bone marrow cells after menopause or discontinuation of estrogen replacement.
1995
Mitogenic responsiveness of human bone cells in vitro to hormones and growth factors decreases with age
1993
Concentration of Insulin-Like Growth Factor (IGF)-I and -II in Iliac Crest Bone Matrix from Pre- and Postmenopausal Women: Relationship to Age, Menopause, Bone Turnover, Bone Volume, and Circulating IGFs1
1998
Reliable and sensitive analysis of occult bone marrow metastases using automated cellular imaging.
2000
Transforming growth factor β (TGF-β) levels in the conditioned media of human bone cells: relationship to donor age, bone volume, and concentration of TGF-β in human bone matrix in vivo
1999
Adjuvant clodronate treatment improves the overall survival of primary breast cancer patients with micrometastases to bone marrow - a longtime follow-up
2004