Citation Impact
Citing Papers
In Vitro Evaluation of the Disposition of A Novel Cysteine Protease Inhibitor
2000
Cardiovascular and Metabolic Alterations in Mice Lacking Both β1- and β2-Adrenergic Receptors
1999 StandoutNobel
Drug Interactions with Grapefruit Juice
1997
Bayesian Forecasting and Prediction of Tacrolimus Concentrations in Pediatric Liver and Adult Renal Transplant Recipients
2003
Predicting Oral Absorption and Bioavailability
2003
Increased tacrolimus levels in a pediatric renal transplant patient attributed to chronic diarrhea
2000
Mechanism of Inhibition of Protein-tyrosine Phosphatases by Vanadate and Pervanadate
1997 Standout
Vanadate-stimulated oxidation of NAD(P)H
1989
The influence of drug-like concepts on decision-making in medicinal chemistry
2007 Standout
Sirolimus, but not the structurally related RAD (everolimus), enhances the negative effects of cyclosporine on mitochondrial metabolism in the rat brain
2001
Effects of the Antifungal Agents on Oxidative Drug Metabolism
2000
Regulation of force and intracellular calcium transients by cyclic AMP generated by forskolin, MDL 17,043 and isoprenaline, and its modulation by muscarinic receptor agents: a novel mechanism for accentuated antagonism
1989
Vanadate-stimulated oxidation of NAD(P)H in the presence of biological membranes and other sources of O2−
1990
Free radicals, metals and antioxidants in oxidative stress-induced cancer
2006 Standout
Posaconazole or Fluconazole for Prophylaxis in Severe Graft-versus-Host Disease
2007 Standout
Cytochrome P450 3A
1999
Elevated tacrolimus trough levels in association with mycophenolate mofetil-induced diarrhea: A case report
2001
Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease
2004 Standout
Mechanisms of Clinically Relevant Drug Interactions Associated with Tacrolimus
2002
Nanoparticles Enhance Therapeutic Efficiency by Selectively Increased Local Drug Dose in Experimental Colitis in Rats
2005
Tephrostratigraphy and the Acheulian to Middle Stone Age transition in the Kapthurin Formation, Kenya
2002
Microemulsion-based media as novel drug delivery systems
2000 Standout
Nanoparticles in inflammatory bowel disease: Particle targeting versus pH-sensitive delivery
2006
The pharmacokinetics and metabolic disposition of tacrolimus: A comparison across ethnic groups
2001
PLGA-based nanoparticles: An overview of biomedical applications
2012 Standout
A New Substrate Specificity for Acyl Transferase Domains of the Ascomycin Polyketide Synthase in Streptomyces hygroscopicus
2002
P‐glycoprotein and Drug Therapy in Organ Transplantation
1999
New discoveries of Australopithecus at Maka in Ethiopia
1993 Nature
Pharmacokinetics of tacrolimus during the early phase after heart transplantation
2001
Role of P-Glycoprotein and Cytochrome P450 3A in Limiting Oral Absorption of Peptides and Peptidomimetics†
1998
2007 Guidelines for the Management of Arterial Hypertension
2007 Standout
The Renal H-K-ATPase:Physiological Significance and Role in Potassium Homeostasis
1993
Targeting multidrug resistance in cancer
2006 Standout
Allergic Rhinitis and Its Impact on Asthma
2001 Standout
COMBINED IMMUNOSUPPRESSION WITH CYCLOSPORINE (NEORAL) AND SDZ RAD IN NON-HUMAN PRIMATE LUNG TRANSPLANTATION: SYSTEMATIC PHARMACOKINETIC-BASED TRIALS TO IMPROVE EFFICACY AND TOLERABILITY 1
2000
Lineage-Specific Expansions of Retroviral Insertions within the Genomes of African Great Apes but Not Humans and Orangutans
2005 StandoutNobel
Geology and palaeontology of the Late Miocene Middle Awash valley, Afar rift, Ethiopia
2001 Nature
Antimicrobial activity of metals: mechanisms, molecular targets and applications
2013 Standout
Clinical Pharmacokinetics and Pharmacodynamics of Tacrolimus in Solid Organ Transplantation
2004 Standout
Early human use of marine resources and pigment in South Africa during the Middle Pleistocene
2007 StandoutNature
Polyphenols: food sources and bioavailability
2004 Standout
Negative chronotropic and inotropic effects exerted by diadenosine hexaphosphate (AP6A) via A1‐adenosine receptors
1996
Sequence diversity in CYP3A promoters and characterization of the genetic basis of polymorphic CYP3A5 expression
2001 Standout
α-Adrenoceptors
1994
Lack of a Clinically Significant Pharmacokinetic Interaction between Fenofibrate and Pravastatin in Healthy Volunteers
2000
The Multifunctional Fish Gill: Dominant Site of Gas Exchange, Osmoregulation, Acid-Base Regulation, and Excretion of Nitrogenous Waste
2004 Standout
Ezetimibe
2005
Human Cytochrome P450 Enzymes: A Status Report Summarizing Their Reactions, Substrates, Inducers, and Inhibitors
1997
Increased tacrolimus levels during diarrhea
2001
The revolution that wasn't: a new interpretation of the origin of modern human behavior
2000 Standout
Micropatterned coculture of primary human hepatocytes and supportive cells for the study of hepatotropic pathogens
2015 StandoutNobel
HepaRG human hepatic cell line utility as a surrogate for primary human hepatocytes in drug metabolism assessment in vitro
2010
Cytochrome P450 enzymes in drug metabolism: Regulation of gene expression, enzyme activities, and impact of genetic variation
2013 Standout
Inhibition of H+,K+-ATPase by hinesol, a major component of So-jutsu, by interaction with enzyme in the E1 state
2000
THE EFFECT OF GUT METABOLISM ON TACROLIMUS BIOAVAILABILITY IN RENALTRANSPLANT RECIPIENTS1,2
2001
In vitro antitrypanosomal activity of plant terpenes against Trypanosoma brucei
2011 StandoutNobel
Immunotherapy in Elderly Transplant Recipients
2009
Rotavirus infection as cause of tacrolimus elevation in solid‐organ‐transplanted children
2001
The Biosynthetic Logic of Polyketide Diversity
2009 Standout
Developmental Pharmacology — Drug Disposition, Action, and Therapy in Infants and Children
2003 Standout
Glucose-6-Phosphate Dehydrogenase in the Pentose Phosphate Pathway Is Localized in Vanadocytes of the Vanadium-Rich Ascidian,Ascidia sydneiensis samea
1998
Vanadate blocks cyclic AMP-induced Stimulation of sodium and water transport in amphibian epithelia
1979 Nature
Contributions of hepatic and intestinal metabolism and P-glycoprotein to cyclosporine and tacrolimus oral drug delivery
1997
Cardiac α-adrenoceptors: postjunctional and prejunctional
1986
Alpha-Adrenergic Receptor Subtypes
1980 StandoutNobel
Activation of adenylate cyclase by vanadate
1979 Nature
Characterization of A1 adenosine receptors in atrial and ventricular myocardium from diseased human hearts.
1989
Two distinct subfractions in isolated Saccharomyces cerevisiae plasma membranes
1983 StandoutNobel
Receptors for Purines and Pyrimidines
1998 Standout
Effect of a New FunctionalCYP3A4Polymorphism on Calcineurin Inhibitors‘ Dose Requirements and Trough Blood Levels in Stable Renal Transplant Patients
2011
Alpha1-adrenergic receptors in guinea pig myocardium: Identification by binding of a new radioligand, (3H)-prazosin
1979
Sex Differences in Pharmacokinetics and Pharmacodynamics
2004
African climate change and faunal evolution during the Pliocene–Pleistocene
2004 Standout
Fluorine and Fluorinated Motifs in the Design and Application of Bioisosteres for Drug Design
2018 Standout
Fire As an Engineering Tool of Early Modern Humans
2009 StandoutScience
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Chronic heart failure in the guinea pig increases cardiac α1- and β-adrenoceptors
1980
Emergence of Modern Human Behavior: Middle Stone Age Engravings from South Africa
2002 StandoutScience
Molecular Properties That Influence the Oral Bioavailability of Drug Candidates
2002 Standout
Ages for the Middle Stone Age of Southern Africa: Implications for Human Behavior and Dispersal
2008 StandoutScience
African Homo erectus : Old Radiometric Ages and Young Oldowan Assemblages in the Middle Awash Valley, Ethiopia
1994 Science
Alpha-adrenergic receptors in liver membranes: Delineation with subtype selective radioligands
1981 StandoutNobel
IN VITRO AND IN VIVO DRUG INTERACTIONS INVOLVING HUMAN CYP3A
1998
Electron paramagnetic resonance studies and insulin-like effects of vanadium in rat adipocytes
1981
Imidazole derivatives, part IX selective reactions of functionalized imidazo[1,2-a]pyridines: stereospecific synthesis of 5,6-dihydroimidazo[1,2-a]pyridines
1994
Glutathione reduces cytoplasmic vanadate mechanism and physiological implications
1980
Molecular biological approaches to the accumulation and reduction of vanadium by ascidians
2003
Adenosine‐activated potassium current in smooth muscle cells isolated from the pig coronary artery.
1993
Vanadate — a new tool for biologists
1979 Nature
Stereoselective Cyclopropanation Reactions
2003 Standout
A Howiesons Poort tradition of engraving ostrich eggshell containers dated to 60,000 years ago at Diepkloof Rock Shelter, South Africa
2010 Standout
Practice Guidelines for the Diagnosis and Management of Aspergillosis: 2016 Update by the Infectious Diseases Society of America
2016 Standout
The fate of cytoplasmic vanadium. Implications on (NA,K)-ATPase inhibition.
1979
Is the Role of the Small Intestine in First-Pass Metabolism Overemphasized?
1999
Targeted disruption of the mouse beta1-adrenergic receptor gene: developmental and cardiovascular effects.
1996 StandoutNobel
Early evidence of San material culture represented by organic artifacts from Border Cave, South Africa
2012 Standout
The Chemistry and Biochemistry of Vanadium and the Biological Activities Exerted by Vanadium Compounds
2004 Standout
Alterations in dynamic heart rate control in the β1-adrenergic receptor knockout mouse
1998 StandoutNobel
19F and 31P NMR spectroscopy of G protein alpha subunits. Mechanism of activation by Al3+ and F-
1991 StandoutNobel
Mechanisms of Action of Vanadium
1984
Systemic Antifungal Agents
1998
Cytochrome P4503APolymorphisms and Immunosuppressive Drugs: An Update
2007
Inhibition of membrane phosphotyrosyl-protein phosphatase activity by vanadate
1982 StandoutNobel
Insulin-like stimulation of glucose oxidation in rat adipocytes by vanadyl (IV) ions
1980 Nature
Effect of Vanadate on Elevated Blood Glucose and Depressed Cardiac Performance of Diabetic Rats
1985 Science
Herbal Modulation of P‐Glycoprotein
2004
The role of metals in carcinogenesis: biochemistry and metabolism.
1981
The insulin-mimetic effects of vanadate in isolated rat adipocytes. Dissociation from effects of vanadate as a (Na+-K+)ATPase inhibitor.
1980
Molecular Mechanisms of Myocardial Remodeling
1999 Standout
Implications of Recent Clinical Trials for the National Cholesterol Education Program Adult Treatment Panel III Guidelines
2004 Standout
INSIGHTS FROM IN VIVO MODIFICATION OF ADRENERGIC RECEPTOR GENE EXPRESSION
1998 StandoutNobel
Decreased Catecholamine Sensitivity and β-Adrenergic-Receptor Density in Failing Human Hearts
1982 Standout
Structural Alert/Reactive Metabolite Concept as Applied in Medicinal Chemistry to Mitigate the Risk of Idiosyncratic Drug Toxicity: A Perspective Based on the Critical Examination of Trends in the Top 200 Drugs Marketed in the United States
2011
Aquaporins in the Kidney: From Molecules to Medicine
2002 StandoutNobel
Increased tacrolimus levels during diarrhea
2001
Irreversible Inhibitors of Serine, Cysteine, and Threonine Proteases
2002 Standout
A New Functional CYP3A4 Intron 6 Polymorphism Significantly Affects Tacrolimus Pharmacokinetics in Kidney Transplant Recipients
2011
Increase of Gi alpha in human hearts with dilated but not ischemic cardiomyopathy.
1990
Works of Ingelore Hackbarth being referenced
Metabolism of the immunosuppressant tacrolimus in the small intestine: cytochrome P450, drug interactions, and interindividual variability.
1995
Small Intestinal Metabolism of the 3-Hydroxy-3-methylglutaryl-Coenzyme A Reductase Inhibitor Lovastatin and Comparison with Pravastatin
1999
Adenosine inhibition of catecholamine-induced increase in force of contraction in guinea-pig atrial and ventricular heart preparations. Evidence against a cyclic AMP- and cyclic GMP-dependent effect.
1984
Metabolism of the macrolide immunosuppressant, tacrolimus, by the pig gut mucosa in the Ussing chamber
1996
Drug Interactions and Interindividual Variability of Ciclosporin Metabolism in the Small Intestine
1996
Mechanism of gastric antisecretory effect of SCH 28080
1986
Stimulatory effect of vanadate on (Na+ + K+)-ATPase activity and on 3H-ouabain-binding in a cat heart cell membrane preparation
1979 Nature
The positive inotropic effect of phenylephrine in the presence of propranolol. Increase in time to peak force and in relaxation time without increase in c-AMP
1978
Comparison of Cytochrome P-450-Dependent Metabolism and Drug Interactions of the 3-Hydroxy-3-methylglutaryl-CoA Reductase Inhibitors Lovastatin and Pravastatin in the Liver
1999
Metabolism and Transport of the Macrolide Immunosuppressant Sirolimus in the Small Intestine
1998
Positive inotropism of vanadate in cat papillary muscle
1978 Nature
Effects of vanadate on the c-AMP system of the heart
1980
Effect of vanadate on myocardial force of contraction
1980
Purified cardiac cell membranes with high (Na+ + K+) ATPase activity contain significant NADH-vanadate reductase activity
1979 Nature