Citation Impact
Citing Papers
Frequent Nonrandom Activation of Germ-Line Genes in Human Cancer
2004
Epigenetic memory of active gene transcription is inherited through somatic cell nuclear transfer
2005 StandoutNobel
Genetic Unmasking of an Epigenetically Silenced microRNA in Human Cancer Cells
2007
Conversion of 5-Methylcytosine to 5-Hydroxymethylcytosine in Mammalian DNA by MLL Partner TET1
2009 StandoutScience
The Human let-7a-3 Locus Contains an Epigenetically Regulated MicroRNA Gene with Oncogenic Function
2007
Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis
2012 StandoutNobel
Jagged1-mediated Notch activation induces epithelial-to-mesenchymal transition through Slug-induced repression of E-cadherin
2007
Genetic Disruption of Cytosine DNA Methyltransferase Enzymes Induces Chromosomal Instability in Human Cancer Cells
2005
Tet-Mediated Formation of 5-Carboxylcytosine and Its Excision by TDG in Mammalian DNA
2011 StandoutScience
Epigenetics provides a new generation of oncogenes and tumour-suppressor genes
2006
Genome-scale DNA methylation maps of pluripotent and differentiated cells
2008 StandoutNature
Phenotypic plasticity and the epigenetics of human disease
2007 Nature
DNA Damage Signaling Triggers Degradation of Histone Methyltransferases through APC/CCdh1 in Senescent Cells
2011
Elements of cancer immunity and the cancer–immune set point
2017 StandoutNature
Oncology Meets Immunology: The Cancer-Immunity Cycle
2013 Standout
DNA hypermethylation in tumorigenesis: epigenetics joins genetics
2000
The history of cancer epigenetics
2004 Standout
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
DNA methylation patterns and epigenetic memory
2002 Standout
Chromatin Modifications and Their Function
2007 Standout
Epithelial-Mesenchymal Transitions in Development and Disease
2009 Standout
Epigenetics in human disease and prospects for epigenetic therapy
2004 StandoutNature
Distribution, silencing potential and evolutionary impact of promoter DNA methylation in the human genome
2007 StandoutNobel
Obesity-induced gut microbial metabolite promotes liver cancer through senescence secretome
2013 StandoutNature
The ICF syndrome, a DNA methyltransferase 3B deficiency and immunodeficiency disease
2003
Proliferation, cell cycle and apoptosis in cancer
2001 StandoutNature
Influence of tumour micro-environment heterogeneity on therapeutic response
2013 StandoutNature
DNA methylation in health and disease
2000
DNMT1 is required to maintain CpG methylation and aberrant gene silencing in human cancer cells
2002
Loss of genomic methylation causes p53-dependent apoptosis and epigenetic deregulation
2001
MPDL3280A (anti-PD-L1) treatment leads to clinical activity in metastatic bladder cancer
2014 StandoutNature
Epigenetics in Cancer
2008 Standout
Dnmt3a and Dnmt3b Are Transcriptional Repressors That Exhibit Unique Localization Properties to Heterochromatin
2001
The complex language of chromatin regulation during transcription
2007 StandoutNature
Methylation matters
2001
The key to development: interpreting the histone code?
2005
Maintenance of self‐renewal ability of mouse embryonic stem cells in the absence of DNA methyltransferases Dnmt1, Dnmt3a and Dnmt3b
2006
Histone demethylation by a family of JmjC domain-containing proteins
2005 StandoutNature
Distinct epigenetic changes in the stromal cells of breast cancers
2005
The epigenetics of cancer etiology
2004
Transgenerational Stability of the Arabidopsis Epigenome Is Coordinated by CG Methylation
2007
Gadd45a promotes epigenetic gene activation by repair-mediated DNA demethylation
2007 Nature
Aberrant patterns of DNA methylation, chromatin formation and gene expression in cancer
2001
Direct interaction between DNMT1 and G9a coordinates DNA and histone methylation during replication
2006
Mechanisms of drug combinations: interaction and network perspectives
2009 Standout
Gene Silencing in Cancer in Association with Promoter Hypermethylation
2003 Standout
TET enzymes, TDG and the dynamics of DNA demethylation
2013 StandoutNature
Epigenetic disruption of ribosomal RNA genes and nucleolar architecture in DNA methyltransferase 1 (Dnmt1) deficient cells
2007
The diverse functions of histone lysine methylation
2005 Standout
Epigenetic regulation of gene expression: how the genome integrates intrinsic and environmental signals
2003 Standout
Genome maintenance mechanisms for preventing cancer
2001 StandoutNature
Highly Integrated Single-Base Resolution Maps of the Epigenome in Arabidopsis
2008 Standout
Decitabine—Bedside to bench
2006
Polycomb complexes repress developmental regulators in murine embryonic stem cells
2006 StandoutNature
The Polycomb group protein EZH2 directly controls DNA methylation
2005 StandoutNature
Insights into social insects from the genome of the honeybee Apis mellifera
2006 StandoutNature
Above and Within the Genome: Epigenetics Past and Present
2001
Escape from gene silencing in ICF syndrome: evidence for advanced replication time as a major determinant
2000
The role of MET1 in RNA-directed de novoand maintenance methylation of CG dinucleotides
2004
The age of cancer
2000 Nature
Role of Tet proteins in 5mC to 5hmC conversion, ES-cell self-renewal and inner cell mass specification
2010 StandoutNature
The Retinoblastoma Binding Protein RBP2 Is an H3K4 Demethylase
2007 StandoutNobel
A stem cell–like chromatin pattern may predispose tumor suppressor genes to DNA hypermethylation and heritable silencing
2007
Chromatin modification and epigenetic reprogramming in mammalian development
2002
Human DNA methylomes at base resolution show widespread epigenomic differences
2009 StandoutNature
VEGF in Signaling and Disease: Beyond Discovery and Development
2019 Standout
The fundamental role of epigenetic events in cancer
2002 Standout
A 3D Map of the Human Genome at Kilobase Resolution Reveals Principles of Chromatin Looping
2014 Standout
In vitro reprogramming of fibroblasts into a pluripotent ES-cell-like state
2007 StandoutNature
Linking the epigenetic ‘language’ of covalent histone modifications to cancer
2004
Relationship between Gene Body DNA Methylation and Intragenic H3K9me3 and H3K36me3 Chromatin Marks
2011
MGMT Gene Silencing and Benefit from Temozolomide in Glioblastoma
2005 Standout
Nuclear Reprogramming in Cells
2008 StandoutScienceNobel
Immune Modulation in Cancer with Antibodies
2013 StandoutNobel
Loss of imprinting in colorectal cancer linked to hypomethylation of H19 and IGF2.
2002
Opposing effects of DNA hypomethylation on intestinal and liver carcinogenesis
2005
Genome sequencing and analysis of the model grass Brachypodium distachyon
2010 StandoutNature
Epigenetic Reprogramming in Mammalian Development
2001 StandoutScience
Overexpression of a splice variant of DNA methyltransferase 3b, DNMT3b4, associated with DNA hypomethylation on pericentromeric satellite regions during human hepatocarcinogenesis
2002
Establishment and Maintenance of Genomic Methylation Patterns in Mouse Embryonic Stem Cells by Dnmt3a and Dnmt3b
2003
Broken Limits to Life Expectancy
2002 StandoutScience
Inhibition of DNA methylation and histone deacetylation prevents murine lung cancer.
2003
Frequent hypomethylation of multiple genes overexpressed in pancreatic ductal adenocarcinoma.
2003
Cancer Genome Landscapes
2013 StandoutScience
Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression
2012 StandoutNobel
Neoantigens in cancer immunotherapy
2015 StandoutScience
A DNA insulator prevents repression of a targeted X-linked transgene but not its random or imprinted X inactivation
2006 StandoutNobel
Real-time in vivo imaging of p16Ink4a reveals cross talk with p53
2009
CpG Methylation of Human Papillomavirus Type 16 DNA in Cervical Cancer Cell Lines and in Clinical Specimens: Genomic Hypomethylation Correlates with Carcinogenic Progression
2003
Works of Ina Rhee being referenced
CpG methylation is maintained in human cancer cells lacking DNMT1
2000 Nature
Phase I study of the anti-α5β1 monoclonal antibody MINT1526A with or without bevacizumab in patients with advanced solid tumors
2018
DNMT1 and DNMT3b cooperate to silence genes in human cancer cells
2002 Nature
Histone modifications and silencing prior to DNA methylation of a tumor suppressor gene
2003
Clinical activity, safety, and biomarkers of MPDL3280A, an engineered PD-L1 antibody in patients with metastatic renal cell carcinoma (mRCC).
2013
Randomized Phase II Trial of Parsatuzumab (Anti-EGFL7) or Placebo in Combination with FOLFOX and Bevacizumab for First-Line Metastatic Colorectal Cancer
2017