Citation Impact
Citing Papers
A hexahistidine-Zn 2+ -dye label reveals STIM1 surface exposure
2007 StandoutNobel
Mismatch Repair-dependent Iterative Excision at Irreparable O6-Methylguanine Lesions in Human Nuclear Extracts
2006 StandoutNobel
β-Catenin Controls Hair Follicle Morphogenesis and Stem Cell Differentiation in the Skin
2001 Standout
Human Mismatch Repair
2005 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Genetic Heterogeneity in Erythrokeratodermia Variabilis: Novel Mutations in the Connexin Gene GJB4 (Cx30.3) and Genotype-Phenotype Correlations
2003
Cell mechanics and the cytoskeleton
2010 StandoutNature
Incorporation of connexins into plasma membranes and gap junctions
2004
Connexin26 mutations associated with the most common form of non- syndromic neurosensory autosomal recessive deafness (DFNB1) in Mediterraneans
1997
A common founder for the 35delG GJB2gene mutation in connexin 26 hearing impairment
2001
Intracellular Trafficking Pathways in the Assembly of Connexins into Gap Junctions
1999
Connexin disorders of the skin
2005
Structural organization of gap junction channels
2005
TP53 Mutations in Human Cancers: Origins, Consequences, and Clinical Use
2009 Standout
A common polymorphism acts as an intragenic modifier of mutant p53 behaviour
2000 StandoutNobel
Microsatellite Instability in Colorectal Cancer
2010 Standout
Beyond the gap: functions of unpaired connexon channels
2003
A Catalytic Antibody Produces Fluorescent Tracers of Gap Junction Communication in Living Cells
2001 StandoutNobel
Role for the p53 homologue p73 in E2F-1-induced apoptosis
2000 StandoutNatureNobel
p53 polymorphisms: cancer implications
2009
Papillomaviruses Causing Cancer: Evasion From Host-Cell Control in Early Events in Carcinogenesis
2000 Standout
Expanding The Phenotypic Spectrum of Cx26 Disorders: Bart–Pumphrey Syndrome is Caused by a Novel Missense Mutation in GJB2
2004
Differential Expression of Connexins During Stratification of Human Keratinocytes
2000
Influence of Metabolism on Epigenetics and Disease
2013 StandoutNobel
Global Cancer Statistics, 2002
2005 Standout
Newborn Hearing Screening — A Silent Revolution
2006 Standout
The role of TP53 in Cervical carcinogenesis
2003
Connexin disorders of the ear, skin, and lens
2004
Mutations in the myosin VIIA gene cause non-syndromic recessive deafness
1997
Targeted Inactivation of Fh1 Causes Proliferative Renal Cyst Development and Activation of the Hypoxia Pathway
2007
Choosing anticancer drug targets in the postgenomic era
1999 StandoutNobel
Chapter 1: Human Papillomavirus and Cervical Cancer--Burden and Assessment of Causality
2003
Basic mechanisms of high‐risk human papillomavirus‐induced carcinogenesis: Roles of E6 and E7 proteins
2007
Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular Pathology
2015 Standout
Functional Domain Mapping and Selective Trans-dominant Effects Exhibited by Cx26 Disease-causing Mutations
2004
Roles of Met-34, Cys-64, and Arg-75 in the Assembly of Human Connexin 26
2003
Transport and Function of Cx26 Mutants Involved in Skin and Deafness Disorders
2003
Hydrolytic function of Exo1 in mammalian mismatch repair
2014 StandoutNobel
Common tumour p53 mutations in immortalized cells from Hupki mice heterozygous at codon 72
2007
The role of the E6-p53 interaction in the molecular pathogenesis of HPV
1999
The p53 pathway
1999
Gap junctions in the inner ear: Comparison of distribution patterns in different vertebrates and assessement of connexin composition in mammals
2003
Quadrivalent Vaccine against Human Papillomavirus to Prevent Anogenital Diseases
2007 Standout
Mutations in the hair cortex keratin hHb6 cause the inherited hair disease monilethrix
1997
ESDN, a Novel Neuropilin-like Membrane Protein Cloned from Vascular Cells with the Longest Secretory Signal Sequence among Eukaryotes, Is Up-regulated after Vascular Injury
2001 StandoutNobel
Cochlear gap junctions coassembled from Cx26 and 30 show faster intercellular Ca2+ signaling than homomeric counterparts
2005
Connexin gene mutations in human genetic diseases
2000
Two Different Connexin 26 Mutations in an Inbred Kindred Segregating Non-Syndromic Recessive Deafness: Implications for Genetic Studies in Isolated Populations
1997
Skin Cancers after Organ Transplantation
2003 Standout
Mutation analysis and molecular genetics of epidermolysis bullosa
1999
Connexin-Aequorin Chimerae Report Cytoplasmic Calcium Environments along Trafficking Pathways Leading to Gap Junction Biogenesis in Living COS-7 Cells
1998
Relation between choice of partner and high frequency of connexin-26 deafness
2000
Identification of the Ubiquitin Carrier Proteins, E2s, Involved in Signal-induced Conjugation and Subsequent Degradation of IκBα
1999 StandoutNobel
A Protein Conjugation System in Yeast with Homology to Biosynthetic Enzyme Reaction of Prokaryotes
2000 StandoutNobel
Blinded by the Light: The Growing Complexity of p53
2009 Standout
Mutations in a novel cochlear gene cause DFNA9, a human nonsyndromic deafness with vestibular dysfunction
1998
Papillomaviruses and cancer: from basic studies to clinical application
2002 StandoutNobel
Functional genomic analysis of C. elegans chromosome I by systematic RNA interference
2000 StandoutNature
The causal relation between human papillomavirus and cervical cancer
2002 Standout
Case–Control Study of Human Papillomavirus and Oropharyngeal Cancer
2007 Standout
The cochlear F-box protein OCP1 associates with OCP2 and connexin 26
2004
EXO1-A multi-tasking eukaryotic nuclease
2004
Clinical features of the prevalent form of childhood deafness, DFNB1, due to a connexin-26 gene defect: implications for genetic counselling
1999
Diverse functions of vertebrate gap junctions
1998
Gap junction systems in the mammalian cochlea
2000
Polymorphisms in the p53 pathway
2006
Connexin gene pathology
2003
A constitutively open potassium channel formed by KCNQ1 and KCNE3
2000 StandoutNature
p53 and Human Cancer: The First Ten Thousand Mutations
1999
Targeted Ablation of Connexin26 in the Inner Ear Epithelial Gap Junction Network Causes Hearing Impairment and Cell Death
2002
High carrier frequency of the 35delG deafness mutation in European populations
2000
A missense mutation in connexin26, D66H, causes mutilating keratoderma with sensorineural deafness (Vohwinkel's syndrome) in three unrelated families
1999
Structure of the connexin 26 gap junction channel at 3.5 Å resolution
2009 Nature
Effect of the codon 72 polymorphism (c.215G>C, p.Arg72Pro) in combination with somatic sequence variants in theTP53gene on survival in patients with advanced ovarian carcinoma
2004
Vanilloid Receptor–Related Osmotically Activated Channel (VR-OAC), a Candidate Vertebrate Osmoreceptor
2000 Standout
Transgenic expression of a dominant-negative connexin26 causes degeneration of the organ of Corti and non-syndromic deafness
2003
SWELL1, a Plasma Membrane Protein, Is an Essential Component of Volume-Regulated Anion Channel
2014 StandoutNobel
Synaptotagmins: Why So Many?
2002 StandoutNobel
Hoxc13 mutant mice lack external hair
1998 StandoutNobel
TP53 mutations in human cancers: functional selection and impact on cancer prognosis and outcomes
2007
Connexin30 mutations responsible for hidrotic ectodermal dysplasia cause abnormal hemichannel activity
2004
A TP53 polymorphism is associated with increased risk of colorectal cancer and with reduced levels of TP53 mRNA
2003
The effects of connexin phosphorylation on gap junctional communication
2003
p53 codon 72 polymorphism and risk of cervical cancer in UK
1998
The Emerging p53 Gene Family
1999 StandoutNobel
Mutations in the gene for connexin 26 (GJB2) that cause hearing loss have a dominant negative effect on connexin 30
2003
Role of Bak in UV-induced apoptosis in skin cancer and abrogation by HPV E6 proteins
2000
Integrins
2002 Standout
A Pro51Ser mutation in the COCH gene is associated with late onset autosomal dominant progressive sensorineural hearing loss with vestibular defects
1999
KCNQ4, a Novel Potassium Channel Expressed in Sensory Outer Hair Cells, Is Mutated in Dominant Deafness
1999
OTOF Encodes Multiple Long and Short Isoforms: Genetic Evidence That the Long Ones Underlie Recessive Deafness DFNB9
2000
ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data
2010 Standout
A ubiquitin-like system mediates protein lipidation
2000 StandoutNatureNobel
Negative Control of p53 by Sir2α Promotes Cell Survival under Stress
2001 Standout
Epidemiologic Classification of Human Papillomavirus Types Associated with Cervical Cancer
2003 Standout
Genetic testing as part of the Early Hearing Detection and Intervention (EHDI) process
2004
TP53 polymorphisms and lung cancer risk: a systematic review and meta-analysis
2003
Apg16p is required for the function of the Apg12p–Apg5p conjugate in the yeast autophagy pathway
1999 StandoutNobel
The C-terminal Region of an Apg7p/Cvt2p Is Required for Homodimerization and Is Essential for Its E1 Activity and E1-E2 Complex Formation
2001 StandoutNobel
Regulation of Gap Junctions by Phosphorylation of Connexins
2000
Targeted epidermal expression of mutant Connexin 26(D66H) mimics true Vohwinkel syndrome and provides a model for the pathogenesis of dominant connexin disorders
2003
Trafficking, Assembly, and Function of a Connexin43-Green Fluorescent Protein Chimera in Live Mammalian Cells
1999
Complete switch from Mdm2 to human papillomavirus E6-mediated degradation of p53 in cervical cancer cells
2001 StandoutNobel
Molecular markers for cell types of the inner ear and candidate genes for hearing disorders
1998
Cx26 deafness: mutation analysis and clinical variability
1999
The Reversible Modification Regulates the Membrane-Binding State of Apg8/Aut7 Essential for Autophagy and the Cytoplasm to Vacuole Targeting Pathway
2000 StandoutNobel
Synthesis and assembly of connexins in vitro into homomeric and heteromeric functional gap junction hemichannels
1999
p53 polymorphism and risk of cervical cancer
1998 Nature
Connexin interaction patterns in keratinocytes revealed morphologically and by FRET analysis
2005
kakapo, a Gene Required for Adhesion Between and Within Cell Layers in Drosophila, Encodes a Large Cytoskeletal Linker Protein Related to Plectin and Dystrophin
1998
Frequency and distribution of GJB2 (connexin 26) and GJB6 (connexin 30) mutations in a large North American repository of deaf probands
2003
A Conserved LIM Protein That Affects Muscular Adherens Junction Integrity and Mechanosensory Function in Caenorhabditis elegans
1999 StandoutNobel
A Structural Scaffolding of Intermediate Filaments in Health and Disease
1998 Science
Multicolor and Electron Microscopic Imaging of Connexin Trafficking
2002 StandoutScienceNobel
Actinin-associated LIM Protein: Identification of a Domain Interaction between PDZ and Spectrin-like Repeat Motifs
1997
Plasma Membrane Channels Formed by Connexins: Their Regulation and Functions
2003
Functional Characterization of Connexin43 Mutations Found in Patients With Oculodentodigital Dysplasia
2005
Clustering of connexin 43–enhanced green fluorescent protein gap junction channels and functional coupling in living cells
2000
Surfing the p53 network
2000 StandoutNature
The ubiquitin-proteasome pathway: on protein death and cell life
1998 StandoutNobel
Life cycle of connexins in health and disease
2006 Standout
Emerging issues of connexin channels: biophysics fills the gap
2001
Evaluation of the Combined Effect of p53 Codon 72 Polymorphism and Hotspot Mutations in Response to Anticancer Drugs
2005
Genetic susceptibility to non-polyposis colorectal cancer
1999
trans-dominant inhibition of connexin-43 by mutant connexin-26: implications for dominant connexin disorders affecting epidermal differentiation
2001
A Diagnostic Paradigm for Childhood Idiopathic Sensorineural Hearing Loss
2004
TP53 polymorphism, HPV infection, and risk of cervical cancer.
2001
Role of plectin in cytoskeleton organization and dynamics
1998
Mutation of the E6-AP Ubiquitin Ligase Reduces Nuclear Inclusion Frequency While Accelerating Polyglutamine-Induced Pathology in SCA1 Mice
1999 StandoutNobel
Works of I.M. Leigh being referenced
Multiple Epidermal Connexins are Expressed in Different Keratinocyte Subpopulations Including Connexin 31
2001
Linkage of Monilethrix to the Trichocyte and Epithelial Keratin Gene Cluster on 12q11-q13
1996
Fumarate hydratase mutations and predisposition to cutaneous leiomyomas, uterine leiomyomas and renal cancer
2005
Plectin deficiency results in muscular dystrophy with epidermolysis bullosa
1996
Connexin 26 mutations in hereditary non-syndromic sensorineural deafness
1997 StandoutNature
Role of a p53 polymorphism in the development of human papilloma-virus-associated cancer
1998 Nature
Germline deletions of EXO1 do not cause colorectal tumors and lesions which are null for EXO1 do not have microsatellite instability
2003
Recessive epidermolysis bullosa simplex associated with plectin mutations: infantile respiratory complications in two unrelated cases
1997