Citation Impact
Citing Papers
Normal development and behaviour of mice lacking the neuronal cell-surface PrP protein
1992 StandoutNatureNobel
Distinct prion proteins in short and long scrapie incubation period mice
1987 StandoutNobel
Genetic Aspects of Unconventional Virus Infections: The Basis of the Virino Hypothesis
2007
NMR structure of the mouse prion protein domain PrP(121–231)
1996 StandoutNatureNobel
Chemistry and biology of prions
1992
Structural studies of the scrapie prion protein using mass spectrometry and amino acid sequencing
1993
Different allelic effects of the codons 136 and 171 of the prion protein gene in sheep with natural scrapie
1995
Scrapie Strain Variation and Its Implications
1991
Transgenetic studies implicate interactions between homologous PrP isoforms in scrapie prion replication
1990 StandoutNobel
The Genomic Identity of Different Strains of Mouse Scrapie Is Expressed in Hamsters and Preserved on Reisolation in Mice
1989
Identification of five allelic variants of the sheep PrP gene and their association with natural scrapie
1995
A 'unified theory' of prion propagation
1991 Nature
Swaledale sheep affected by natural scrapie differ significantly in PrP genotype frequencies from healthy sheep and those selected for reduced incidence of scrapie
1993
To what Extent is Strain Variation Evidence for an Independent Genome in the Agent of the Transmissible Spongiform Encephalopathies?
1996
Linkage of a prion protein missense variant to Gerstmann–Sträussler syndrome
1989 StandoutNatureNobel
The Neurochemistry of Prion Diseases
1993
The disease characteristics of different strains of scrapie in Sinc congenic mouse lines: implications for the nature of the agent and host control of pathogenesis
1991
Structural Clues to Prion Replication
1994 StandoutScienceNobel
Genetic and Infectious Prion Diseases
1993
Transgenic mice expressing hamster prion protein produce species-specific scrapie infectivity and amyloid plaques
1989 StandoutNobel
PrP genotypes and experimental scrapie in orally inoculated Suffolk sheep in the United States.
1997
Selective Neuronal Targeting in Prion Disease
1997 StandoutNobel
Human prion diseases
1994 StandoutNobel
Transmissible spongiform encephalopathies (TSE) virus-induced amyloidoses of the central nervous system (CNS)
1991
Eight prion strains have PrPSc molecules with different conformations
1998 Nobel
Propagation of prions with artificial properties in transgenic mice expressing chimeric PrP genes
1993
Prion propagation in mice expressing human and chimeric PrP transgenes implicates the interaction of cellular PrP with another protein
1995 StandoutNobel
Chimeric prion protein expression in cultured cells and transgenic mice
1992 StandoutNobel
Prion (PrPSc)-specific epitope defined by a monoclonal antibody
1997 StandoutNatureNobel
Mice devoid of PrP are resistant to scrapie
1993 Standout
The exceptionally small size of the scrapie agent
1966
Scrapie prions aggregate to form amyloid-like birefringent rods
1983 StandoutNobel
Scrapie-Induced Changes in the Percentage of Polymorphonuclear Neutrophils in Mouse Peripheral Blood
1972
Transmissible spongiform encephalopathies: The threat of BSE to man
1990
Nature of the Scrapie Agent
1967 Nature
Interspecies transmission of Creutzfeldt-Jakob disease to Syrian hamsters with reference to clinical syndromes and strains of agent.
1978
Measurement of the scrapie agent using an incubation time interval assay
1982 StandoutNobel
Detection of the Scrapie Agent in Tissues of Normal Mice
1968 Nature
No Mouse PMN Leukocyte Depression after Inoculation with Brain Tissue from Multiple Sclerosis or Spongiform Encephalopathies
1974 StandoutNatureNobel
Comparison of Scrapie and Transmissible Mink Encephalopathy in Hamsters. II. Clinical Signs, Pathology, and Pathogenesis
1975
Prion isolate specified allotypic interactions between the cellular and scrapie prion proteins in congenic and transgenic mice.
1994 StandoutNobel
The sequential development of the brain lesions of scrapie in three strains of mice
1968
Kuru with incubation periods exceeding two decades
1982 StandoutNobel
Oral Transmission of Kuru, Creutzfeldt-Jakob Disease, and Scrapie to Nonhuman Primates
1980
Unraveling prion diseases through molecular genetics
1989 StandoutNobel
EXPERIMENTAL TRANSMISSION OF SCRAPIE TO RATS
1963
Transmission experiments with multiple sclerosis: an interim report.
1966
Precautions in Medical Care of, and in Handling Materials from, Patients with Transmissible Virus Dementia (Creutzfeldt-Jakob Disease)
1977 Nobel
Evidence that the Transmission of One Source of Scrapie Agent to Hamsters Involves Separation of Agent Strains from a Mixture
1978
Scrapie: A transmissible and hereditary disease of sheep
1962
Toward Development of Assays for Scrapie-Specific Antibodies
1981 StandoutNobel
Biohazards of Investigations on the Transmissible Spongiform Encephalopathies
1980 StandoutNobel
GENETICS OF PRIONS
1997 StandoutNobel
Viremia in Experimental Creutzfeldt-Jakob Disease
1978 Science
Inoculation of Voles, Chinese Hamsters, Gerbils and Guinea-pigs with Scrapie Brain Material
1972
ENCEPHALOPATHY IN MICE PRODUCED BY INOCULATION WITH SCRAPIE BRAIN MATERIAL
1961
The future of cloning
1999 StandoutNatureNobel
Scrapie in mice
1973
Evolution of a Strain of CJD That Induces BSE-Like Plaques
1997 Science
Studies on the Heat Stability and Chromatographic Behaviour of the Scrapie Agent
1964
Genetical control of the incubation period in mice of the neurological disease, scrapie
1964
Attempts to release the scrapie agent from tissue debris
1967
Brain tissue from persons dying of creutzfeldt‐jakob disease causes scrapie‐like encephalopathy in goats
1980 StandoutNobel
An experimental examination of the scrapie agent in cell membrane mixtures
1971
Novel Proteinaceous Infectious Particles Cause Scrapie
1982 StandoutScienceNobel
DNA Synthesis in Scrapie-Affected Mouse Brain
1967
Survival of Creutzfeldt-Jakob-Disease Virus in Formol-Fixed Brain Tissue
1976 StandoutNobel
Nature of the Scrapie Agent: Self-replication and Scrapie
1967 Nature
Identification of a Protein That Purifies with the Scrapie Prion
1982 StandoutScienceNobel
Experimental Scrapie in the Mouse
1963
Experimental transmission of mouse passaged scrapie to goats, sheep, rats and hamsters
1965
Course of Experimental Scrapie Virus Infection in the Goat
1974
The Scrapie Agent: “A Virus by Any Other Name”
1991
Evidence for the Conformation of the Pathologic Isoform of the Prion Protein Enciphering and Propagating Prion Diversity
1996 StandoutScienceNobel
Temporary and Permanent Modifications to a Single Strain of Mouse Scrapie on Transmission to Rats and Hamsters
1987
The Histopathy of the Brain of Goats Affected with Scrapie
1961
Prion Diseases and the BSE Crisis
1997 StandoutScienceNobel
A hypothalamic neuronal cell line persistently infected with scrapie prions exhibits apoptosis
1997 StandoutNobel
Scrapie: A Transmissible Hereditary Disease of Sheep
1960 Nature
Unconventional Viruses and the Origin and Disappearance of Kuru
1977 ScienceNobel
Propagation of prion strains through specific conformers of the prion protein
1997 StandoutNobel
An electron microscopic study of natural scrapie sheep brain: Further observations on virus-like particles and paramyxovirus-like tubules
1974
Prions
1998 StandoutNobel
Reversible Chemical Modification of the Scrapie Agent
1981 StandoutScienceNobel
Scrapie: A Prototype Slow Infection
1972
Infection-Specific Particle from the Unconventional Slow Virus Diseases
1984 ScienceNobel
Biology and Structure of Scrapie Prions
1986 StandoutNobel
A protease-resistant protein is a structural component of the Scrapie prion
1983 StandoutNobel
Genetical control of the concentration of ME7 scrapie agent in the brain of mice
1969
An experimental examination of the scrapie agent in cell membrane mixtures
1971
Unusual Topogenic Sequence Directs Prion Protein Biogenesis
1990 StandoutScienceNobel
Immunohistochemical demonstration of glial fibrillary acidic protein in scrapie
1983
Transmissible and non-transmissible neurodegenerative disease: similarities in age of onset and genetics in relation to aetiology
1986
Altered plasma membranes in experimental scrapie
1971
Virologic and Neurohistologic Findings in Dairy Goats Affected with Natural Scrapie
1980
Three scrapie prion isolates exhibit different accumulation patterns of the prion protein scrapie isoform.
1993
Scrapie-infected murine neuroblastoma cells produce protease-resistant prion proteins
1988 StandoutNobel
Homozygosity for prion protein alleles encoding glutamine-171 renders sheep susceptible to natural scrapie.
1994 StandoutNobel
THE INFECTIVE PROCESS IN SCRAPIE
1968
A cellular gene encodes scrapie PrP 27-30 protein
1985 StandoutNobel
Transmission of Two Subacute Spongiform Encephalopathies of Man (Kuru and Creutzfeldt–Jakob Disease) to New World Monkeys
1971 StandoutNatureNobel
A comparison of the biochemical changes induced in mouse brain by cuprizone toxicity and by scrapie infection
1974
A Preliminary Report on the Experimental Host Range of the Transmissible Mink Encephalopathy Agent
1969
Further studies of the infectivity and stability of extracts and homogenates derived from scrapie affected mouse brains
1969
Prions: Novel Infectious Pathogens
1984 StandoutNobel
Transmission of Scrapie in Hamsters
1985 StandoutNobel
The Pathology of Experimental Scrapie in the Dairy Goat
1961
Does the Agent of Scrapie Replicate without Nucleic Acid ?
1967 Nature
Transmission by Contact of Scrapie in Mice
1964
Physical and Chemical Properties of the Transmissible Mink Encephalopathy Agent
1969
Scrapie and cellular PrP isoforms are encoded by the same chromosomal gene
1986 StandoutNobel
Replication of distinct scrapie prion isolates is region specific in brains of transgenic mice and hamsters.
1992 StandoutNobel
An analysis of natural scrapie in suffolk sheep
1965
Molecular Biology of Prion Diseases
1991 StandoutScienceNobel
Transmissible mink encephalopathy: pathogenesis and nature of the aetiological agent
1972
In vitro Replication of Scrapie Agent in a Neuronal Model: Infection of PC12 Cells
1984
Is the Scrapie Agent a Viroid?
1972
Maternal and lateral transmission of scrapie in sheep
1974
Natural Infection of Suffolk Sheep with Scrapie Virus
1982
A comparison of some biological characteristics of the mouse-passaged scrapie agents, 22A and ME7
1969
Antibodies to a scrapie prion protein
1984 StandoutNatureNobel
Conservation of the cellular gene encoding the scrapie prion protein
1986 StandoutNobel
Spontaneous Neurodegeneration in Transgenic Mice with Mutant Prion Protein
1990 StandoutScienceNobel
Transmission experiments with a scrapie-like encephalopathy of mink
1970
Experimental Subacute Spongiform Virus Encephalopathies in Primates and Other Laboratory Animals
1973 StandoutScienceNobel
Creutzfeldt-Jakob Disease: Hypothesis for High Incidence in Libyan Jews in Israel
1974 StandoutScienceNobel
Works of I.H. Pattison being referenced
Experimental production of scrapie-resistant Swaledale sheep.
1977
Detection of the Scrapie Agent in Tissues of Normal Mice and in Tumours of Tumour-bearing but Otherwise Normal Mice
1968 Nature
Unsuccessful Attempts to Transmit Scrapie by Nematode Parasites
1968
Experimental Transmission of Scrapie To Goats and Sheep By the Oral Route
1961
The astrocytic reaction in experimental scrapie in the rat.
1967
Resistance of the scrapie agent to formalin
1965
The Astrocytic Reaction in Experimental Scrapie in the Rat
1967
Scrapie in sheep selectively bred for high susceptibility
1974 Nature
Distribution of the scrapie agent in the tissues of experimentally inoculated goats
1962
Spread of scrapie by contact to goats and sheep
1968
Experimental Production of Scrapie in Goats
1959
Brain Cell Cultures from Mice Affected with Scrapie or Fed with Cuprizone
1971
An Examination of the Action of Whole Blood, Blood Cells or Serum on the Goat Scrapie Agent
1964
Further Observations on the Production of Scrapie in Sheep by Oral Dosing with Foetal Membranes from Scrapie-Affected Sheep
1974
Spread of scrapie to sheep and goats by oral dosing with foetal membranes from scrapie-affected sheep
1972
MYOPATHY IN SHEEP
1957
Histological Observations on Experimental Scrapie in the Mouse
1963
Further Observations on the Experimental Production of Scrapie in Goats and Sheep
1960
Clinical and Histological Observations on Cuprizonc Toxicity and Scrapie in Mice
1971
Detection of the Scrapie Agent in Tissues of Normal Mice with Special Reference to the Possibility of Accidental Laboratory Contamination
1971
Scrapie Produced Experimentally in Goats With Special Reference To the Clinical Syndrome
1961
The establishment of sheep flocks of predictable susceptibility to experimental scrapie
1975
William Hunting and The Veterinary Record
1988
Further Experimental Observations on Scrapie
1961
Unsuccessful Attempts to Produce Disease with Tissues from Mice Fed on a Diet Containing Cuprizone
1973
Dialysis of the Scrapie Agent
1964
The Relative Susceptibility of Sheep, Goats and Mice to Two Types of the Goat Scrapie Agent
1966
In‐vitro growth of pieces of brain from scrapie‐affected mice
1967
Modification of a Strain of Mouse-adapted Scrapie by Passage through Rats
1968