Standout Papers
Citation Impact
Citing Papers
Global increase and geographic convergence in antibiotic consumption between 2000 and 2015
2018 Standout
Cd-hit: a fast program for clustering and comparing large sets of protein or nucleotide sequences
2006 Standout
A mucosal vaccine against Chlamydia trachomatis generates two waves of protective memory T cells
2015 Science
Phage Lytic Enzyme Cpl-1 as a Novel Antimicrobial for Pneumococcal Bacteremia
2003
An enzymatic toolkit for selective proteolysis, detection, and visualization of mucin-domain glycoproteins
2020 StandoutNobel
Cochrane Database of Systematic Reviews
2003 Standout
Global, regional, and national age–sex specific all-cause and cause-specific mortality for 240 causes of death, 1990–2013: a systematic analysis for the Global Burden of Disease Study 2013
2014 Standout
Are the pneumococcal polysaccharide vaccines effective? Meta-analysis of the prospective trials
2000
Prevalence, Determinants, and Molecular Epidemiology of Streptococcus pneumoniae Isolates Colonizing the Nasopharynx of Healthy Children in Rome
2002
Pneumococcal nasopharyngeal carriage in children following heptavalent pneumococcal conjugate vaccination in infancy
2003
Potential Contribution by Nontypable Haemophilus influenzae in Protracted and Recurrent Acute Otitis Media
2009
Use of mass media campaigns to change health behaviour
2010 Standout
Nationwide Surveillance of NasopharyngealStreptococcus pneumoniaeIsolates from Children with Respiratory Infection, Switzerland, 1998–1999
2003
Enhanced Diagnosis of Pneumococcal Meningitis with Use of the Binax NOW Immunochromatographic Test ofStreptococcus pneumoniaeAntigen: A Multisite Study
2009
Pneumococcal Carriage and Otitis Media Induce Salivary Antibodies to Pneumococcal Capsular Polysaccharides in Children
2002
The microbiota in adaptive immune homeostasis and disease
2016 StandoutNature
Global, regional, and national causes of under-5 mortality in 2000–15: an updated systematic analysis with implications for the Sustainable Development Goals
2016 Standout
Can available interventions end preventable deaths in mothers, newborn babies, and stillbirths, and at what cost?
2014 Standout
Burden of disease caused by Streptococcus pneumoniae in children younger than 5 years: global estimates
2009 Standout
Immunologic correlates of protection induced by vaccination
2001
Spread ofStreptococcus pneumoniaeand Antibiotic‐ResistantS. pneumoniaefrom Day‐Care Center Attendees to Their Younger Siblings
2002
Vaccines: Correlates of Vaccine‐Induced Immunity
2008
Global burden of childhood pneumonia and diarrhoea
2013 Standout
Decline in Invasive Pneumococcal Disease after the Introduction of Protein–Polysaccharide Conjugate Vaccine
2003 Standout
Safety and immunogenicity of a nonavalent pneumococcal vaccine conjugated to CRM197 administered simultaneously but in a separate syringe with diphtheria, tetanus and pertussis vaccines in Gambian infants
2000
Effectiveness of the 23‐Valent Polysaccharide Vaccine against Invasive Pneumococcal Disease in Navajo Adults
2003
Dual Detection of Fungal Infections in Drosophila via Recognition of Glucans and Sensing of Virulence Factors
2006 StandoutNobel
Protective Efficacy of a Second Pneumococcal Conjugate Vaccine against Pneumococcal Acute Otitis Media in Infants and Children: Randomized, Controlled Trial of a 7-Valent Pneumococcal Polysaccharide-Meningococcal Outer Membrane Protein Complex Conjugate Vaccine in 1666 Children
2003
Prevention of otitis media: Role of pneumococcal conjugate vaccines in reducing incidence and antibiotic resistance
2002
The evidence for using conjugate vaccines to protect HIV-infected children against pneumococcal disease
2007
Natural history of untreated otitis media
2003
Understanding the tumor immune microenvironment (TIME) for effective therapy
2018 Standout
The Diagnosis and Management of Acute Otitis Media
2013 Standout
Streptococcus pneumoniae Nasopharyngeal Carriage Prevalence, Serotype Distribution, and Resistance Patterns among Children on Lombok Island, Indonesia
2001
Streptococcus pneumoniae colonisation: the key to pneumococcal disease
2004 Standout
Postlicensure Surveillance for Pneumococcal Invasive Disease After Use of Heptavalent Pneumococcal Conjugate Vaccine in Northern California Kaiser Permanente
2004
Pneumococcal serotypes from acute otitis media in rural Kentucky
2002
Early Management of Suspected Bacterial Meningitis and Meningococcal Septicaemia in Adults
2003
Pneumococcal conjugate vaccines: proceedings from an Interactive Symposium at the 41st Interscience Conference on Antimicrobial Agents and Chemotherapy
2003
The Burden of Respiratory Syncytial Virus Infection in Young Children
2009 Standout
Pneumococcal capsular polysaccharides conjugated to protein D for prevention of acute otitis media caused by both Streptococcus pneumoniae and non-typable Haemophilus influenzae: a randomised double-blind efficacy study
2006
Cholesterol, inflammation and innate immunity
2015
Effectiveness of heptavalent pneumococcal conjugate vaccine in children younger than five years of age for prevention of pneumonia
2002
Vaccination of day-care center attendees reduces carriage of Streptococcus pneumoniae among their younger siblings
2003
Population Snapshot of EmergentStreptococcus pneumoniaeSerotype 19A in the United States, 2005
2008
Effectiveness of Heptavalent Pneumococcal Conjugate Vaccine in Children Younger Than 5 Years of Age for Prevention of Pneumonia
2006
How to compare the efficacy of conjugate vaccines to prevent acute otitis media?
2009
Prevention of otitis media: Now a reality?
2009
A role for Streptococcus pneumoniae in virus-associated pneumonia
2004
Effectiveness of seven-valent pneumococcal conjugate vaccine against invasive pneumococcal disease: a matched case-control study
2006
Immunogenicity of Pneumococcal Vaccine in Renal Transplant Recipients—Three Year Follow‐up of a Randomized Trial
2007
Epidemiology of Invasive <EMPH TYPE="ITAL">Streptococcus pneumoniae</EMPH> Infections in the United States, 1995-1998<SUBTITLE>Opportunities for Prevention in the Conjugate Vaccine Era</SUBTITLE>
2001
Global, regional, and national causes of child mortality in 2008: a systematic analysis
2010 Standout
Heptavalent pneumococcal vaccine conjugated to outer membrane protein of Neisseria meningitidis serogroup b and nasopharyngeal carriage of Streptococcus pneumoniae in infants
2003
Efficacy of nine-valent pneumococcal conjugate vaccine against pneumonia and invasive pneumococcal disease in The Gambia: randomised, double-blind, placebo-controlled trial
2005
Sensorineural hearing loss in children
2005 Standout
Efficacy of Intranasal Virosomal Influenza Vaccine in the Prevention of Recurrent Acute Otitis Media in Children
2002
Inhibition of Pneumococcal Carriage in Mice by Subcutaneous Immunization with Peptides from the Common Surface Protein Pneumococcal Surface Adhesin A
2002
Clinical Features and Prognostic Factors in Adults with Bacterial Meningitis
2004 Standout
Global phylogeography of Mycobacterium tuberculosis and implications for tuberculosis product development
2007
Outpatient antibiotic use in Europe and association with resistance: a cross-national database study
2005 Standout
Understanding the mechanisms and drivers of antimicrobial resistance
2015 Standout
Graft-versus-host disease
2009 Standout
Increasing Prevalence of Multidrug-ResistantStreptococcus pneumoniaein the United States
2000
Magnetic resonance spectroscopy reveals that activated monocytes contribute to neuronal injury in SIV neuroAIDS
2005
Confronting the pneumococcus: a target shift or bullet change?
2000
Global, regional, and national causes of child mortality: an updated systematic analysis for 2010 with time trends since 2000
2012 Standout
Lower Respiratory Tract Infections Among American Indian and Alaska Native Children and the General Population of U.S. Children
2005
Nasopharyngeal Carriage ofStreptococcus pneumoniaein Finnish Children Younger Than 2 Years Old
2001
Antimicrobial Use and Colonization with Erythromycin‐ResistantStreptococcus pneumoniaein Greece during the First 2 Years of Life
2000
Do Antibodies to Pneumococcal Surface Adhesin A Prevent Pneumococcal Involvement in Acute Otitis Media?
2001
Sickle-cell disease
2010 Standout
The challenge of emerging and re-emerging infectious diseases
2004 StandoutNature
Outpatient antibiotic prescribing in the United States: 2000 to 2010
2014
Sustained Reductions in Invasive Pneumococcal Disease in the Era of Conjugate Vaccine
2009 Standout
Evidence-based interventions for improvement of maternal and child nutrition: what can be done and at what cost?
2013 Standout
Competition among Streptococcus pneumoniae for intranasal colonization in a mouse model
2000
Changing Epidemiology of Invasive Pneumococcal Disease Among Older Adults in the Era of Pediatric Pneumococcal Conjugate Vaccine
2005
Can acute otitis media caused by Haemophilus influenzae be distinguished from that caused by Streptococcus pneumoniae?
2003
Emergence of a Multiresistant Serotype 19A Pneumococcal Strain Not Included in the 7-Valent Conjugate Vaccine as an Otopathogen in Children
2007
Pneumococcal nasopharyngeal colonization in young South Indian infants
2001
Which Pneumococcal Serogroups Cause the Most Invasive Disease: Implications for Conjugate Vaccine Formulation and Use, Part I
2000
What works? Interventions for maternal and child undernutrition and survival
2008 Standout
Community-Wide Vaccination with the Heptavalent Pneumococcal Conjugate Significantly Alters the Microbiology of Acute Otitis Media
2004
Effect of a nonavalent conjugate vaccine on carriage of antibiotic-resistant Streptococcus pneumoniae in day-care centers
2003
Outcome of penicillin-nonsusceptible Streptococcus pneumoniae meningitis: a nested case-control study
2002
Geographic diversity and temporal trends of antimicrobial resistance in Streptococcus pneumoniae in the United States
2003
Heterologous Epitope-Scaffold Prime∶Boosting Immuno-Focuses B Cell Responses to the HIV-1 gp41 2F5 Neutralization Determinant
2011 StandoutNobel
Reduction of Nasopharyngeal Carriage ofStreptococcus pneumoniaeafter Administration of a 9‐Valent Pneumococcal Conjugate Vaccine to Toddlers Attending Day Care Centers
2002
Invasive Pneumococcal Disease Caused by Nonvaccine Serotypes Among Alaska Native Children With High Levels of 7-Valent Pneumococcal Conjugate Vaccine Coverage
2007
Efficacy of a Pneumococcal Conjugate Vaccine against Acute Otitis Media
2001 Standout
Effect of Introduction of the Pneumococcal Conjugate Vaccine on Drug-Resistant Streptococcus pneumoniae
2006
The Nature of Small-Airway Obstruction in Chronic Obstructive Pulmonary Disease
2004 Standout
Infection in Solid-Organ Transplant Recipients
2007 Standout
Historical Changes in Pneumococcal Serogroup Distribution: Implications for the Era of Pneumococcal Conjugate Vaccines
2002
Technical Report: Prevention of Pneumococcal Infections, Including the Use of Pneumococcal Conjugate and Polysaccharide Vaccines and Antibiotic Prophylaxis
2000
Use of vaccines as probes to define disease burden
2014
Postlicensure evaluation of the effectiveness of seven valent pneumococcal conjugate vaccine
2001
Impact of heptavalent pneumococcal conjugate vaccine on invasive disease, antimicrobial resistance and colonization in Alaska Natives: progress towards elimination of a health disparity
2005
Immunological responses to pneumococcal vaccine in frail older people
2008
Efficacy of an 11-Valent Pneumococcal Conjugate Vaccine Against Radiologically Confirmed Pneumonia Among Children Less Than 2 Years of Age in the Philippines
2009
Effects of Large Dosages of Amoxicillin/Clavulanate or Azithromycin on Nasopharyngeal Carriage ofStreptococcus pneumoniae, Haemophilus influenzae,Nonpneumococcal α‐Hemolytic Streptococci, andStaphylococcus aureusin Children with Acute Otitis Media
2002
Cancer vaccines and carbohydrate epitopes
2011
The Changing Epidemiology of Bacterial Meningitis and Invasive Non-meningitic Bacterial Disease in Scotland During the Period 1983-99
2002
Clonal Relationships between Invasive and CarriageStreptococcus pneumoniaeand Serotype‐ and Clone‐Specific Differences in Invasive Disease Potential
2003
Developmental potential in the first 5 years for children in developing countries
2007 Standout
Incidence of Pneumococcal Disease Due to Non–Pneumococcal Conjugate Vaccine (PCV7) Serotypes in the United States during the Era of Widespread PCV7 Vaccination, 1998–2004
2007
Frailty in elderly people
2013 Standout
A Trial of a 9-Valent Pneumococcal Conjugate Vaccine in Children with and Those without HIV Infection
2003
Global, regional, and national causes of child mortality in 2000–13, with projections to inform post-2015 priorities: an updated systematic analysis
2014 Standout
Impact of conjugate pneumococcal vaccines on antibiotic resistance
2008
Effect of Pneumococcal Conjugate Vaccine on Nasopharyngeal Colonization among Immunized and Unimmunized Children in a Community‐Randomized Trial
2007
Immunization of Humans with Recombinant Pneumococcal Surface Protein A (rPspA) Elicits Antibodies That Passively Protect Mice from Fatal Infection withStreptococcus pneumoniaeBearing Heterologous PspA
2000
How many child deaths can we prevent this year?
2003 Standout
Invasive Methicillin-Resistant <EMPH TYPE="ITAL">Staphylococcus aureus</EMPH> Infections in the United States
2007 Standout
Antifouling Coatings: Recent Developments in the Design of Surfaces That Prevent Fouling by Proteins, Bacteria, and Marine Organisms
2010 Standout
Impact of the pneumococcal conjugate vaccine on otitis media
2003
Immunization of healthy adults with a single recombinant pneumococcal surface protein A (PspA) variant stimulates broadly cross-reactive antibodies to heterologous PspA molecules
2000
Invasive pneumococcal infections in children with sickle cell disease in the era of penicillin prophylaxis, antibiotic resistance, and 23-valent pneumococcal polysaccharide vaccination
2003
Observation option toolkit for acute otitis media
2001
Changes in Frequency and Pathogens Causing Acute Otitis Media in 1995–2003
2004
Nasopharyngeal Carriage ofStreptococcus pneumoniaein Healthy Children: Implications for the Use of Heptavalent Pnemococcal Conjugate Vaccine
2002
Sulfatase-activated fluorophores for rapid discrimination of mycobacterial species and strains
2013 StandoutNobel
Pneumococcal conjugate vaccines for preventing vaccine-type invasive pneumococcal disease and X-ray defined pneumonia in children less than two years of age
2009
Fluorine in Pharmaceutical Industry: Fluorine-Containing Drugs Introduced to the Market in the Last Decade (2001–2011)
2013 Standout
Immunization with HIV Gag targeted to dendritic cells followed by recombinant New York vaccinia virus induces robust T-cell immunity in nonhuman primates
2011 StandoutNobel
10-valent pneumococcal nontypeableHaemophilus influenzaePD conjugate vaccine: Synflorix™
2009
Bacterial Infection in Chronic Obstructive Pulmonary Disease in 2000: a State-of-the-Art Review
2001
Pneumococcal conjugate vaccines for preventing otitis media
2014
Intranasal Immunization of Mice with a Mixture of the Pneumococcal Proteins PsaA and PspA Is Highly Protective against Nasopharyngeal Carriage ofStreptococcus pneumoniae
2000
Rational HIV Immunogen Design to Target Specific Germline B Cell Receptors
2013 StandoutScienceNobel
Emerging infectious diseases in the 21st century
2000
Otitis media
2004
Acute otitis media in pediatric medicine: current issues in epidemiology, diagnosis, and management.
2003
Invasive Pneumococcal Disease Burden and Implications for Vaccine Policy in Urban Bangladesh
2007
Emergence of a Novel Swine-Origin Influenza A (H1N1) Virus in Humans
2009 Standout
Rapid Killing of Streptococcus pneumoniae with a Bacteriophage Cell Wall Hydrolase
2001 Science
Insights into the Interaction between Influenza Virus and Pneumococcus
2006
Bacterial Resistance to β-Lactam Antibiotics: Compelling Opportunism, Compelling Opportunity
2005 Standout
Synthetic double-stranded RNA induces innate immune responses similar to a live viral vaccine in humans
2011 StandoutNobel
Using the shortwave infrared to image middle ear pathologies
2016 StandoutNobel
Intranasal Vaccination with Pneumococcal Surface Protein A and Interleukin-12 Augments Antibody-Mediated Opsonization and Protective Immunity againstStreptococcus pneumoniaeInfection
2001
Contribution of vaccines to our understanding of pneumococcal disease
2011
Pneumococcal capsular polysaccharides conjugated to protein D for prevention of acute otitis media caused by both Streptococcus pneumoniae and non‐typable Haemophilus influenzae: a randomised double‐blind efficacy study
2006
Pneumococcal Carriage in Children in The Netherlands: a Molecular Epidemiological Study
2001
Molecular pathogenesis of pneumococcal pneumonia
2001
Inhibition of Pneumococcal Adherence to Human Nasopharyngeal Epithelial Cells by Anti-PsaA Antibodies
2003
The pneumococcus: carriage, disease and conjugate vaccines
2002
Recognition of pneumolysin by Toll-like receptor 4 confers resistance to pneumococcal infection
2003
Efficacy of Pneumococcal Vaccination in Children Younger Than 24 Months: A Meta-Analysis
2009
Oral paliperidone extended-release: chemistry, pharmacodynamics, pharmacokinetics and metabolism, clinical efficacy, safety and tolerability
2012
Vaccine‐Preventable Pediatric Postmeningitic Sensorineural Hearing Loss in Southern India
2004
Reduction of Frequent Otitis Media and Pressure-Equalizing Tube Insertions in Children After Introduction of Pneumococcal Conjugate Vaccine
2007
Effect of conjugate pneumococcal vaccine followed by polysaccharide pneumococcal vaccine on recurrent acute otitis media: a randomised study
2003
Trends in Acute Otitis Media-Related Health Care Utilization by Privately Insured Young Children in the United States, 1997–2004
2008
The Engagement of Activating FcγRs Inhibits Primate Lentivirus Replication in Human Macrophages
2006 StandoutNobel
Dynamics of nasopharyngeal colonization by potential respiratory pathogens
2002
National Impact of Universal Childhood Immunization With Pneumococcal Conjugate Vaccine on Outpatient Medical Care Visits in the United States
2006
Antibody-enhanced pneumococcal adherence requires IgA1 protease
2003
Variable host–pathogen compatibility in Mycobacterium tuberculosis
2006
Continued Impact of Pneumococcal Conjugate Vaccine on Carriage in Young Children
2009
Ability of Pneumococcal Serotypes and Clones To Cause Acute Otitis Media: Implications for the Prevention of Otitis Media by Conjugate Vaccines
2003
Pneumococcal conjugate vaccine provides early protective antibody responses in children after related and unrelated allogeneic hematopoietic stem cell transplantation
2006
Population-Based Impact of Pneumococcal Conjugate Vaccine in Young Children
2004
Correlates of Protection Induced by Vaccination
2010 Standout
Effect of Pneumococcal Conjugate Vaccine on Nasopharyngeal Bacterial Colonization During Acute Otitis Media
2006
Works of Ih Chang being referenced
Efficacy, safety and immunogenicity of heptavalent pneumococcal conjugate vaccine in children
2000 Standout
Treatment of patients with cardiovascular disease with L-4F, an apo-A1 mimetic, did not improve select biomarkers of HDL function
2010
Safety and immunogenicity of heptavalent pneumococcal CRM197 conjugate vaccine in infants and toddlers
1999
Design of a Group-Randomized Streptococcus pneumoniae Vaccine Trial
2001
Immunogenicity and Impact on Nasopharyngeal Carriage of a Nonavalent Pneumococcal Conjugate Vaccine
1999
The Effects of Paroxetine on the Pharmacokinetics of Paliperidone Extended-release Tablets
2009
Serological criteria for evaluation and licensure of new pneumococcal conjugate vaccine formulations for use in infants
2003
Efficacy and safety of seven-valent conjugate pneumococcal vaccine in American Indian children: group randomised trial
2003
Estimating the protective concentration of anti-pneumococcal capsular polysaccharide antibodies
2007
Increased cerebral blood volume in HIV‐positive patients detected by functional MRI
1998
Safety and Immunogenicity of Heptavalent Pneumococcal Vaccine Conjugated to CRM197 in United States Infants
1998
Field Trial of A Monovalent and of A Bivalent Mineral Oil Adjuvant Trachoma Vaccine in Taiwan School Children
1967
Efficacy of Heptavalent Conjugate Pneumococcal Vaccine (Wyeth Lederle) in 7,000 Infants and Children: Results of the Northern California Kaiser Permanente Efficacy Trial
1999