Citation Impact
Citing Papers
Aspirin-triggered lipoxin enhances macrophage phagocytosis of bacteria while inhibiting inflammatory cytokine production
2011
Angiotensin II causes hypertension and cardiac hypertrophy through its receptors in the kidney
2006 StandoutNobel
Regulation of phosphoinositide 3-kinase expression in health and disease
2009
Computationally designed sensors detect endogenous Ras activity and signaling effectors at subcellular resolution
2024 StandoutNobel
Switching of the coupling of the β2-adrenergic receptor to different G proteins by protein kinase A
1997 StandoutNatureNobel
Phosphoinositides and signal transduction
2002
COPII-Coated Vesicle Formation Reconstituted with Purified Coat Proteins and Chemically Defined Liposomes
1998 StandoutNobel
The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis
2005 StandoutNobel
Chemokines and leukocyte traffic
1998 StandoutNature
ADP-ribosylation Factor and Rho Proteins Mediate fMLP-dependent Activation of Phospholipase D in Human Neutrophils
1998
The Fork head transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans
1997 StandoutNatureNobel
Oncogenic kinase signalling
2001 StandoutNature
Role of ERas in promoting tumour-like properties in mouse embryonic stem cells
2003 StandoutNatureNobel
Ras signaling on the Golgi
2006
Pro-resolving lipid mediators are leads for resolution physiology
2014 StandoutNature
High-resolution crystal structure of human protease-activated receptor 1
2012 StandoutNatureNobel
G-Protein-coupled Receptors and Fcγ-receptors Mediate Activation of Akt/Protein Kinase B in Human Phagocytes
1997
A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans
1996 StandoutNatureNobel
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN
2006 StandoutNatureNobel
A Functional Phosphatidylinositol 3,4,5-Trisphosphate/Phosphoinositide Binding Domain in the Clathrin Adaptor AP-2 α Subunit. IMPLICATIONS FOR THE ENDOCYTIC PATHWAY
1996
Isolation and Molecular Cloning of Wortmannin-sensitive Bovine Type III Phosphatidylinositol 4-Kinases
1997
Protease‐activated receptors in hemostasis, thrombosis and vascular biology
2005
Analysis of the Catalytic Domain of Phosphatidylinositol 4-Kinase Type II
2002 StandoutNobel
Thrombin signalling and protease-activated receptors
2000 StandoutNature
C-terminal Mutation of G Protein β Subunit Affects Differentially Extracellular Signal-regulated Kinase and c-Jun N-terminal Kinase Pathways in Human Embryonal Kidney 293 Cells
1997
Gβγ-dependent Phosphoinositide 3-Kinase Activation in Hearts with in Vivo Pressure Overload Hypertrophy
2000
Phosphoinositide 3-kinases: A conserved family of signal transducers
1997
PI3Kγ inhibition: towards an 'aspirin of the 21st century'?
2006
Colorectal carcinomas in mice lacking the catalytic subunit of PI(3)Kγ
2000 StandoutNatureNobel
Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death
2012 Standout
Phosphatidylinositol 3-Kinase Mediates the Inhibitory Effect of Epidermal Growth Factor on Calcium-dependent Chloride Secretion
1996
Cloning, Expression, and Localization of 230-kDa Phosphatidylinositol 4-Kinase
1996
Kinase-mediated RAS signaling via membraneless cytoplasmic protein granules
2021
Mitogenic Signaling via G Protein-Coupled Receptors
1996 StandoutNobel
Insulin signalling and the regulation of glucose and lipid metabolism
2001 StandoutNature
A Novel Human Tocopherol-associated Protein
2000
Pharmacological Inhibition of Protein Lipidation
2015
Mammalian MAP kinase signalling cascades
2001 StandoutNature
The PtdIns(3,4)P2 phosphatase INPP4A is a suppressor of excitotoxic neuronal death
2010 StandoutNatureNobel
Seven-transmembrane-spanning receptors and heart function
2002 StandoutNatureNobel
Microarray Analysis and Organization of Circadian Gene Expression in Drosophila
2001 StandoutNobel
New Insights into the Control of MAP Kinase Pathways
1999
Phosphoinositides in cell regulation and membrane dynamics
2006 StandoutNature
Activation Loop Sequences Confer Substrate Specificity to Phosphoinositide 3-Kinase α (PI3Kα)
2001
The Pathways Connecting G Protein-coupled Receptors to the Nucleus through Divergent Mitogen-activated Protein Kinase Cascades
1998
Structural insights into phosphoinositide 3-kinase catalysis and signalling
1999 Nature
Structural Basis of 3-Phosphoinositide Recognition by Pleckstrin Homology Domains
2000
Two Signaling Mechanisms for Activation of αMβ2 Avidity in Polymorphonuclear Neutrophils
1998
Distinct Classes of Phosphatidylinositol 3′-Kinases Are Involved in Signaling Pathways That Control Macroautophagy in HT-29 Cells
2000
Temporal and Spatial Regulation of Chemotaxis
2002
Role of c-Src Tyrosine Kinase in G Protein-coupled Receptorand Gβγ Subunit-mediated Activation of Mitogen-activated Protein Kinases
1996 StandoutNobel
Gβγ Subunits Mediate Src-dependent Phosphorylation of the Epidermal Growth Factor Receptor
1997 StandoutNobel
Phosphatidylinositol 3-Kinase Is an Early Intermediate in the Gβγ-mediated Mitogen-activated Protein Kinase Signaling Pathway
1996 StandoutNobel
Dual modulation of cell survival and cell death by β 2 -adrenergic signaling in adult mouse cardiac myocytes
2001 StandoutNobel
β-Arrestin inhibits NF-κB activity by means of its interaction with the NF-κB inhibitor IκBα
2004 StandoutNobel
Insulin Receptor Substrate 1 Binds Two Novel Splice Variants of the Regulatory Subunit of Phosphatidylinositol 3-Kinase in Muscle and Brain
1996
Defective lymphocyte chemotaxis in β-arrestin2- and GRK6-deficient mice
2002 StandoutNobel
Mitogen-Activated Protein (MAP) Kinase Pathways: Regulation and Physiological Functions*
2001 Standout
Regulation of C. elegans Life-Span by Insulinlike Signaling in the Nervous System
2000 StandoutScienceNobel
ADP-ribosylation factor and phosphatidic acid levels in Golgi membranes during budding of coatomer-coated vesicles
1998 StandoutNobel
Targeting G βγ signaling in arterial vascular smooth muscle proliferation: A novel strategy to limit restenosis
1999 StandoutNobel
Membrane proteomics of phagosomes suggests a connection to autophagy
2008 StandoutNobel
Protection from angiotensin II–mediated vasculotoxic and hypertensive response in mice lacking PI3Kγ
2005
ABHD17 proteins are novel protein depalmitoylases that regulate N-Ras palmitate turnover and subcellular localization
2015
Click-Chemistry Based High Throughput Screening Platform for Modulators of Ras Palmitoylation
2017 StandoutNobel
Cytoskeletal Reorganization by G Protein-Coupled Receptors Is Dependent on Phosphoinositide 3-Kinase γ, a Rac Guanosine Exchange Factor, and Rac
1998
Aging, life span, and senescence
1998 StandoutNobel
Membrane Localization of Phosphatidylinositol 3-Kinase Is Sufficient To Activate Multiple Signal-Transducing Kinase Pathways
1996
1997 StandoutNobel
Cardiac βARK1 inhibition prolongs survival and augments β blocker therapy in a mouse model of severe heart failure
2001 StandoutNobel
Cellular Function of Phosphoinositide 3-Kinases: Implications for Development, Immunity, Homeostasis, and Cancer
2001
Activation and targeting of extracellular signal-regulated kinases by β-arrestin scaffolds
2001 StandoutNobel
Regulation of Mitogen-Activated Protein Kinase Signaling Networks by G Protein-Coupled Receptors
2000
Regulation of nuclear factor κB activation by G-protein-coupled receptors
2001
Computational Alanine Scanning To Probe Protein−Protein Interactions: A Novel Approach To Evaluate Binding Free Energies
1999
daf-2 , an Insulin Receptor-Like Gene That Regulates Longevity and Diapause in Caenorhabditis elegans
1997 StandoutScienceNobel
Activation of phosphoinositide 3-kinase by interaction with Ras and by point mutation.
1996
Targeting RAS Membrane Association: Back to the Future for Anti-RAS Drug Discovery?
2015
Function of PI3Kγ in Thymocyte Development, T Cell Activation, and Neutrophil Migration
2000 StandoutScienceNobel
Molecular Basis for Interactions of G Protein βγ Subunits with Effectors
1998 StandoutScienceNobel
Autophagy as a Regulated Pathway of Cellular Degradation
2000 StandoutScience
Direct control of mitochondrial function by mTOR
2009
The Phosphoinositide 3-Kinase Pathway
2002 StandoutScience
Role of endocytosis in the activation of the extracellular signal-regulated kinase cascade by sequestering and nonsequestering G protein-coupled receptors
2000 StandoutNobel
JNK1 controls mast cell degranulation and IL-1β production in inflammatory arthritis
2010 StandoutNobel
A simple physical model for binding energy hot spots in protein–protein complexes
2002 StandoutNobel
PHOSPHOINOSITIDE KINASES
1998
Works of Ignacio Rubio being referenced
Real-Time Visualization and Quantification of Native Ras Activation in Single Living Cells
2013
Reassessment of the role of FKBP38 in the Rheb/mTORC1 pathway
2009
ORIGINAL ARTICLE: Selective Downregulation of Phosphoinositide 3‐Kinase alpha in Leukocytes During Pregnancy
2009
Interaction of Ras with phosphoinositide 3-kinase γ
1997
TCR-Induced Activation of Ras Proceeds at the Plasma Membrane and Requires Palmitoylation of N-Ras
2010
Live‐cell imaging of endogenous Ras‐GTP illustrates predominant Ras activation at the plasma membrane
2005
Cloning and Characterization of a G Protein-Activated Human Phosphoinositide-3 Kinase
1995 Science
Bifurcation of Lipid and Protein Kinase Signals of PI3Kγ to the Protein Kinases PKB and MAPK
1998 Science
Ras palmitoylation is necessary for N-Ras activation and signal propagation in growth factor signalling
2013
Real-Time Assay of the Interaction of a GST Fusion Protein with a Protein Ligate Using Resonant Mirror Technique
1997