Citation Impact
Citing Papers
In Situ Visualization of the pKM101-Encoded Type IV Secretion System Reveals a Highly Symmetric ATPase Energy Center
2021
Structures of Cas9 Endonucleases Reveal RNA-Mediated Conformational Activation
2014 StandoutScienceNobel
Computational Design of Self-Assembling Protein Nanomaterials with Atomic Level Accuracy
2012 StandoutScienceNobel
TCR ligand density and affinity determine peripheral induction of Foxp3 in vivo
2010 StandoutNobel
Structural bases for F plasmid conjugation and F pilus biogenesis in Escherichia coli
2019
Structure of the Rotor of the V-Type Na + -ATPase from Enterococcus hirae
2005 ScienceNobel
Evidence for VirB4-Mediated Dislocation of Membrane-Integrated VirB2 Pilin during Biogenesis of the Agrobacterium VirB/VirD4 Type IV Secretion System
2010
Genetic manipulation of Patescibacteria provides mechanistic insights into microbial dark matter and the epibiotic lifestyle
2023 StandoutNobel
Membrane curvature regulates the spatial distribution of bulky glycoproteins
2022 StandoutNobel
De novo design of allosterically switchable protein assemblies
2024 StandoutNatureNobel
Structure of a VirD4 coupling protein bound to a VirB type IV secretion machinery
2017
Recent advances in the structural and molecular biology of type IV secretion systems
2014
Discovery and engineering of enhanced SUMO protease enzymes
2018 StandoutNobel
From conjugation to T4S systems in Gram‐negative bacteria: a mechanistic biology perspective
2019
Discovery of archaeal fusexins homologous to eukaryotic HAP2/GCS1 gamete fusion proteins
2022 StandoutNobel
Cardiolipins and biomembrane function
1992
C-terminal domains implicated in the functional surface expression of potassium channels
2003
The I-complex in Leishmania tarentolae is an uniquely-structured F1-ATPase
2004
Physical Principles of Membrane Shape Regulation by the Glycocalyx
2019 StandoutNobel
Comparison of SUMO fusion technology with traditional gene fusion systems: Enhanced expression and solubility with SUMO
2005
High-resolution cryo-electron microscopy structure of the Trypanosoma brucei ribosome
2013 StandoutNatureNobel
Mitochondrial dysfunction, apoptotic cell death, and Alzheimer’s disease
2003
The mechanism of rotating proton pumping ATPases
2010
Mechanisms for T cell receptor triggering
2010
The Agrobacterium VirB/VirD4 T4SS: Mechanism and Architecture Defined Through In Vivo Mutagenesis and Chimeric Systems
2018
Protein–protein interaction and quaternary structure
2008
Integrins Form an Expanding Diffusional Barrier that Coordinates Phagocytosis
2016 StandoutNobel
ELOVL3 Is an Important Component for Early Onset of Lipid Recruitment in Brown Adipose Tissue
2005 StandoutNobel
Accurate design of co-assembling multi-component protein nanomaterials
2014 StandoutNatureNobel
Mechanisms Controlling Mitochondrial Biogenesis and Respiration through the Thermogenic Coactivator PGC-1
1999 Standout
Structure and Function of Mitochondrial Anion Transport Proteins
2001
Action and Traction: Cytoskeletal Control of Receptor Triggering at the Immunological Synapse
2016
Rationalizing membrane protein overexpression
2006
Role of the Biomolecular Energy Gap in Protein Design, Structure, and Evolution
2012 StandoutNobel
Uncoupling protein‐3: a new member of the mitochondrial carrier family with tissue‐specific expression
1997
Loss of cyclophilin D reveals a critical role for mitochondrial permeability transition in cell death
2005 StandoutNature
A Cold-Inducible Coactivator of Nuclear Receptors Linked to Adaptive Thermogenesis
1998 Standout
Coiled Coils Direct Assembly of a Cold-Activated TRP Channel
2006 StandoutNobel
Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation
2013 StandoutNobel
Structure of a type IV secretion system
2014 Nature
Considerations and Challenges in Studying Liquid-Liquid Phase Separation and Biomolecular Condensates
2019 Standout
The mitochondrial uncoupling-protein homologues
2005
Uncoupling protein-2: a novel gene linked to obesity and hyperinsulinemia
1997 Standout
The Mitochondrial Uncoupling Protein: Structural and Genetic Studies
1997
Image processing for electron microscopy single-particle analysis using XMIPP
2008
Uncoupling Protein-3 Is a Mediator of Thermogenesis Regulated by Thyroid Hormone, β3-Adrenergic Agonists, and Leptin
1997
Mechanisms of gene flow in archaea
2017
Functional Halt Positions of Rotary FOF1-ATPase Correlated with Crystal Structures
2008
The coming of age of de novo protein design
2016 StandoutNatureNobel
Conformational changes in the G protein Gs induced by the β2 adrenergic receptor
2011 StandoutNatureNobel
Mitochondrial ATP‐Synthase in the Entorhinal Cortex Is a Target of Oxidative Stress at Stages I/II of Alzheimer's Disease Pathology
2009
Monoglucosyldiacylglycerol, a Foreign Lipid, Can Substitute for Phosphatidylethanolamine in Essential Membrane-associated Functions in Escherichia coli
2004
T Cell Receptor-Proximal Signals Are Sustained in Peripheral Microclusters and Terminated in the Central Supramolecular Activation Cluster
2006
Transmembrane Pickets Connect Cyto- and Pericellular Skeletons Forming Barriers to Receptor Engagement
2018 StandoutNobel
Native UCP1 Displays Simple Competitive Kinetics between the Regulators Purine Nucleotides and Fatty Acids
2004
ATP synthase — a marvellous rotary engine of the cell
2001
A model for p53-induced apoptosis
1997 StandoutNature
Synthetic Multivalent Ligands as Probes of Signal Transduction
2006
What We Talk About When We Talk About Fat
2014 Standout
Secretion systems in Gram-negative bacteria: structural and mechanistic insights
2015
SUMO fusion technology for difficult-to-express proteins
2005
Cytoskeletal Control of CD36 Diffusion Promotes Its Receptor and Signaling Function
2011
Protein structure and dynamics studied by mass spectrometry: H/D exchange, hydroxyl radical labeling, and related approaches
2008
Obesity and the Regulation of Energy Balance
2001 Standout
The rotary mechanism of the ATP synthase
2008
Advanced genetic strategies for recombinant protein expression in Escherichia coli
2004
Cryo-EM structure of a type IV secretion system
2022 StandoutNatureNobel
Novel Mitochondrial Complex II Isolated from Trypanosoma cruzi Is Composed of 12 Peptides Including a Heterodimeric Ip Subunit
2009 StandoutNobel
Mitochondrial uncoupling as a target for drug development for the treatment of obesity
2001
Pathways towards and away from Alzheimer's disease
2004 StandoutNature
Selective Inhibition of Hypoxia-Inducible Factor (HIF) Prolyl-Hydroxylase 1 Mediates Neuroprotection against Normoxic Oxidative Death via HIF- and CREB-Independent Pathways
2009 StandoutNobel
TCR–peptide–MHC interactions in situ show accelerated kinetics and increased affinity
2010 Nature
Direction of actin flow dictates integrin LFA-1 orientation during leukocyte migration
2017 StandoutNobel
Oxidative damage and mitochondrial decay in aging.
1994 Standout
The structural and energetic basis for high selectivity in a high-affinity protein-protein interaction
2010 StandoutNobel
Transport in Proton Conductors for Fuel-Cell Applications: Simulations, Elementary Reactions, and Phenomenology
2004 Standout
Density Variant Glycan Microarray for Evaluating Cross-Linking of Mucin-like Glycoconjugates by Lectins
2012 StandoutNobel
Water as an Active Constituent in Cell Biology
2007 Standout
Nanozymes: Classification, Catalytic Mechanisms, Activity Regulation, and Applications
2019 Standout
Keep It Flexible: Driving Macromolecular Rotary Motions in Atomistic Simulations with GROMACS
2011
Structure of the VirB4 ATPase, alone and bound to the core complex of a type IV secretion system
2012
Synthesis of Glycopolymers for Microarray Applications via Ligation of Reducing Sugars to a Poly(acryloyl hydrazide) Scaffold
2010 StandoutNobel
Type IV secretion systems: Advances in structure, function, and activation
2020
Cyclophilin-D promotes the mitochondrial permeability transition but has opposite effects on apoptosis and necrosis
2004
Structural Biology of Bacterial Type IV Secretion Systems
2015
Is a “Proton Wire” Concerted or Stepwise? A Model Study of Proton Transfer in Carbonic Anhydrase
2003
Multi-State Regulation of the Dihydrogen Phosphate Binding Affinity to a Light- and Heat-Responsive Bis-Urea Receptor
2014 StandoutNobel
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Electrostatic origin of the mechanochemical rotary mechanism and the catalytic dwell of F1-ATPase
2011 StandoutNobel
A role for uncoupling protein‐2 as a regulator of mitochondrial hydrogen peroxide generation
1997
Artificial Molecular Machines
2015 Standout
The Release of Cytochrome c from Mitochondria: A Primary Site for Bcl-2 Regulation of Apoptosis
1997 StandoutScience
Mitochondrial Uncoupling Proteins in Energy Expenditure
2000
GROMACS: High performance molecular simulations through multi-level parallelism from laptops to supercomputers
2015 Standout
Three-dimensional localization of T-cell receptors in relation to microvilli using a combination of superresolution microscopies
2016
Cloning and Characterization of an Uncoupling Protein Homolog: A Potential Molecular Mediator of Human Thermogenesis
1997
Proton Pumping ATPases: Rotational Catalysis, Physiological Roles in Oral Pathogenic Bacteria, and Inhibitors
2022
Noncovalent Cell Surface Engineering: Incorporation of Bioactive Synthetic Glycopolymers into Cellular Membranes
2008 StandoutNobel
Mitochondrial activation chemicals synergize with surface receptor PD-1 blockade for T cell-dependent antitumor activity
2017 StandoutNobel
Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.
1995
Structure-guided SCHEMA recombination generates diverse chimeric channelrhodopsins
2017 StandoutNobel
Distinct influences of peptide-MHC quality and quantity on in vivo T-cell responses
2012 StandoutNobel
Works of Ignacio Aréchaga being referenced
Coexistence of multivalent and monovalent TCRs explains high sensitivity and wide range of response
2005
Conjugation inhibitors compete with palmitic acid for binding to the conjugative traffic ATPase TrwD, providing a mechanism to inhibit bacterial conjugation
2018
Activation of the Uncoupling Protein by Fatty Acids is Modulated by Mutations in the C‐Terminal Region of the Protein
1996
Dimerization of Bovine F1-ATPase by Binding the Inhibitor Protein, IF1
2000 Nobel
Increased Sensitivity of Antigen-Experienced T Cells through the Enrichment of Oligomeric T Cell Receptor Complexes
2011
The Hexameric Structure of a Conjugative VirB4 Protein ATPase Provides New Insights for a Functional and Phylogenetic Relationship with DNA Translocases
2012
Conjugation Inhibitors and Their Potential Use to Prevent Dissemination of Antibiotic Resistance Genes in Bacteria
2017
Over‐expression of Escherichia coli F1Fo–ATPase subunit a is inhibited by instability of the uncB gene transcript
2003 Nobel
Functional Interactions of VirB11 Traffic ATPases with VirB4 and VirD4 Molecular Motors in Type IV Secretion Systems
2013
The rotary mechanism of ATP synthase
2000 Nobel
The Membrane Domain of the Na+-motive V-ATPase from Enterococcus hirae Contains a Heptameric Rotor
2003 Nobel
Self‐assembly of ATP synthase subunit c rings
2002 Nobel
Characterisation of new intracellular membranes in Escherichia coli accompanying large scale over‐production of the b subunit of F1Fo ATP synthase
2000 Nobel
Autoinhibitory Regulation of TrwK, an Essential VirB4 ATPase in Type IV Secretion Systems
2011
Structural independence of conjugative coupling protein TrwB from its Type IV secretion machinery
2013
The Mitochondrial Uncoupling Protein UCP1: A Gated Pore
2001
Effect of hydrophobic sulphydryl reagents on the uncoupling protein and inner‐membrane anion channel of brown‐adipose‐tissue mitochondria
1989
The ATPase Activity of the DNA Transporter TrwB Is Modulated by Protein TrwA
2007
Structural characterization of the TCR complex by electron microscopy
2010
Regulation of the Type IV Secretion ATPase TrwD by Magnesium
2012
Molecular Motors in Bacterial Secretion
2013
A sequence related to a DNA recognition element is essential for the inhibition by nucleotides of proton transport through the mitochondrial uncoupling protein.
1994
Type IV traffic ATPase TrwD as molecular target to inhibit bacterial conjugation
2016
Cysteine residues are not essential for uncoupling protein function
1993
Towards an integrated model of bacterial conjugation
2014
ATPase Activity and Oligomeric State of TrwK, the VirB4 Homologue of the Plasmid R388 Type IV Secretion System
2008