Standout Papers
Citation Impact
Citing Papers
Selective targeting of engineered T cells using orthogonal IL-2 cytokine-receptor complexes
2018 StandoutScienceNobel
Generation of knock-in primary human T cells using Cas9 ribonucleoproteins
2015 StandoutNobel
Tumor-reactive CD4+ T cells develop cytotoxic activity and eradicate large established melanoma after transfer into lymphopenic hosts
2010 StandoutNobel
Tumor-specific Th17-polarized cells eradicate large established melanoma
2008
Spontaneous autoimmunity prevented by thymic expression of a single self-antigen
2006
Mouse models of acute and chronic hepacivirus infection
2017 StandoutScienceNobel
Either a Th17 or a Th1 effector response can drive autoimmunity: conditions of disease induction affect dominant effector category
2008
Aire-Dependent Thymic Development of Tumor-Associated Regulatory T Cells
2013 StandoutScienceNobel
Projection of an Immunological Self Shadow Within the Thymus by the Aire Protein
2002 StandoutScience
A community effect in animal development
1988 StandoutNatureNobel
Destabilization of the complete protein secondary structure on binding to the chaperone GroEL
1994 StandoutNatureNobel
Immunological detection of arrestin, a phototransduction regulatory protein, in the cytosol of nucleated erythrocytes
1989
Peripheral-antigen-expressing cells in thymic medulla: factors in self-tolerance and autoimmunity
1998
Cachectin/tumor necrosis factor-alpha formation in human decidua. Potential role of cytokines in infection-induced preterm labor.
1989 StandoutNobel
Regulatory T Cells
2000 StandoutNobel
Control of Foxp3+ CD25+CD4+ regulatory cell activation and function by dendritic cells
2004
Shaping of the autoreactive T-cell repertoire by a splice variant of self protein expressed in thymic epithelial cells
2000
Regulatory T Cells and Immune Tolerance
2008 StandoutNobel
Evolution of the TIR, Tolls and TLRs: Functional Inferences from Computational Biology
2002 StandoutNobel
IgE and mast cells in allergic disease
2012 Standout
Complete amino acid sequence of the FK506 and rapamycin binding protein, FKBP, isolated from calf thymus
1991
There is more than one interleukin 1
1986
Adoptive immunotherapy of cancer using CD4+ T cells
2009
Assay of bacterial endotoxin (lipopolysaccharide) in human amniotic fluid: Potential usefulness in diagnosis and management of preterm labor
1988
Structure of human cyclophilin and its binding site for cyclosporin A determined by X-ray crystallography and NMR spectroscopy
1991 StandoutNatureNobel
The kinase mTOR regulates the differentiation of helper T cells through the selective activation of signaling by mTORC1 and mTORC2
2011
The tyrosine kinase c-Abl regulates p73 in apoptotic response to cisplatin-induced DNA damage
1999 StandoutNatureNobel
Isoprenylation in regulation of signal transduction by G-protein-coupled receptor kinases
1992 StandoutNatureNobel
Idiotypic Regulation of T Cells in Graft‐Versus‐Host Disease and Autoimmunity
1989
Control of TH17/Treg Balance by Hypoxia-Inducible Factor 1
2011 StandoutNobel
Sampling of complementing self-antigen pools by thymic stromal cells maximizes the scope of central T cell tolerance
2001
Identification of Lps2 as a key transducer of MyD88-independent TIR signalling
2003 StandoutNatureNobel
Promiscuous gene expression in medullary thymic epithelial cells mirrors the peripheral self
2001
The pathogenesis of atherosclerosis: a perspective for the 1990s
1993 StandoutNature
Extrathymic positive selection of αβ T-cell precursors in nude mice
1992 StandoutNatureNobel
Small RNAs are modified with N-glycans and displayed on the surface of living cells
2021 StandoutNobel
STATs: transcriptional control and biological impact
2002 Standout
Cloning and characterization of the cDNAs for human and rabbit interleukin-1 precursor
1985
Identification of a common nucleotide sequence in the 3'-untranslated region of mRNA molecules specifying inflammatory mediators.
1986 StandoutNobel
Immunization of chimpanzees confers protection against challenge with human immunodeficiency virus.
1991 StandoutNobel
Biological and biochemical properties of fibroblast growth factors. Implications for the pathogenesis of atherosclerosis.
1989
T‐T Cell Interactions during Cytotoxic T Lymphocyte (CTL) Responses: T Cell Derived Helper Factor (Interleukin 2) as a Probe to Analyze CTL Responsiveness and Thymic Maturation of CTL Progenitors
1980
Immunocytochemical detection of interleukin 1 within stimulated human monocytes.
1986
Nucleotide sequence of human monocyte interleukin 1 precursor cDNA.
1984
Defective LPS Signaling in C3H/HeJ and C57BL/10ScCr Mice: Mutations in Tlr4 Gene
1998 StandoutScienceNobel
T-cell mitogens cause early changes in cytoplasmic free Ca2+ and membrane potential in lymphocytes
1982 StandoutNatureNobel
Stimulation of the proliferation of human bone cells in vitro by human monocyte products with interleukin-1 activity.
1985
Cachectin and tumour necrosis factor as two sides of the same biological coin
1986 StandoutNatureNobel
Fas Ligand-Induced Apoptosis as a Mechanism of Immune Privilege
1995 StandoutScience
ROLE OF ABERRANT HLA-DR EXPRESSION AND ANTIGEN PRESENTATION IN INDUCTION OF ENDOCRINE AUTOIMMUNITY
1983 Standout
Binding of the von Hippel-Lindau Tumor Suppressor Protein to Elongin B and C
1995 StandoutScienceNobel
Chimeric α 2 -,β 2 -Adrenergic Receptors: Delineation of Domains Involved in Effector Coupling and Ligand Binding Specificity
1988 StandoutScienceNobel
The Biochemistry, Biology, and Role of Interleukin 2 in the Induction of Cytotoxic T Cell and Antibody‐Forming B Cell Responses
1982
Interleukin 1 stimulates platelet activating factor production in cultured human endothelial cells
1986
Analysis of Autoimmunity through Experimental Models of Thyroiditis and Allergic Encephalomyelitis
1980
Cloning, sequence and expression of two distinct human interleukin-1 complementary DNAs
1985 Nature
The role of macrophages in the acute-phase response: SAA inducer is closely related to lymphocyte activating factor and endogenous pyrogen
1981
Monocyte-derived inhibitor of interleukin 1 induced by human cytomegalovirus
1985
Induction of murine interleukin 1: stimuli and responsive primary cells.
1987 StandoutNobel
The production of fibrinolysis inhibitors as a parameter of the activation state in murine macrophages
1979
Clonal Deletion Versus Clonal Anergy: The Role of the Thymus in Inducing Self Tolerance
1990 StandoutScienceNobel
Prostaglandin E production by human blood monocytes and mouse peritoneal macrophages.
1978
Interleukin 1 enhances T-dependent immune responses by amplifying the function of dendritic cells.
1987 StandoutNobel
Functional Specificity of Thymus-Dependent Lymphocytes
1977 StandoutScienceNobel
The opsin family of proteins
1986
Inhibition of cell proliferation by interleukin-1 derived from monocytic leukemia cells.
1986
T Cell Control of Antibody Production
1974
Interleukin 1α mRNA in virus-transformed T and B cells
1986 StandoutNobel
Action of Endotoxin on Lymphoid Cells
1977
Cloning and expression of murine interleukin-1 cDNA in Escherichia coli
1984 Nature
Novel Proteinaceous Infectious Particles Cause Scrapie
1982 StandoutScienceNobel
The Biology of Interleukin-2
2007
Cloning of complementary DNA encoding T-cell replacing factor and identity with B-cell growth factor II
1986 StandoutNatureNobel
Role of interleukin 1 in anti-immunoglobulin-induced B cell proliferation.
1983
Essential role of β-adrenergic receptor kinase 1 in cardiac development and function
1996 StandoutNobel
β-Adrenergic Receptor Kinase-2 and β-Arrestin-2 as Mediators of Odorant-Induced Desensitization
1993 StandoutScienceNobel
Accessory cell function of human B cells. I. Production of both interleukin 1-like activity and an interleukin 1 inhibitory factor by an EBV-transformed human B cell line.
1984
Two distinct factors are required for induction of T-cell growth
1980 Nature
Cachectin: More Than a Tumor Necrosis Factor
1987 StandoutNobel
A quantitative test to estimate neutralizing antibodies to the hepatitis C virus: cytofluorimetric assessment of envelope glycoprotein 2 binding to target cells.
1996 StandoutNobel
Foxp3+natural regulatory T cells preferentially form aggregates on dendritic cellsin vitroand actively inhibit their maturation
2008 StandoutNobel
B Cell Growth and Differentiation Factors
1984
Critical role of the neutrophil-associated high-affinity receptor for IgE in the pathogenesis of experimental cerebral malaria
2011
Stimulation by human interleukin 1 of cartilage breakdown and production of collagenase and proteoglycanase by human chondrocytes but not by human osteoblasts in vitro
1984
Synthesis of thymosin beta 4 by peritoneal macrophages and adherent spleen cells.
1982
Immunoregulatory Feedback Between Interleukin-1 and Glucocorticoid Hormones
1986 Science
Cyclophilin: A Specific Cytosolic Binding Protein for Cyclosporin A
1984 Science
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
1983 Standout
A Macrophage-Derived Factor Required by Plasmacytomas for Survival and Proliferation in Vitro
1986 Science
CD4 T Cell Tolerance to Human C-reactive Protein, an Inducible Serum Protein, Is Mediated by Medullary Thymic Epithelium
1998
Modulation of alveolar macrophage-driven fibroblast proliferation by alternative macrophage mediators.
1986
The receptor kinase family: primary structure of rhodopsin kinase reveals similarities to the beta-adrenergic receptor kinase.
1991 StandoutNobel
Macrophages from Babesia and malaria infected mice are primed for monokine release
1984
Osteoblasts mediate interleukin 1 stimulation of bone resorption by rat osteoclasts.
1986
Prostacyclin Synthesis Induced in Vascular Cells by Interleukin-1
1985 Science
An adjuvant formulation that selectively elicits the formation of antibodies of protective isotypes and of cell-mediated immunity
1986
Restoration of mismatch repair to nuclear extracts of H6 colorectal tumor cells by a heterodimer of human MutL homologs.
1995 StandoutNobel
Murine lymphoid procoagulant activity induced by bacterial lipopolysaccharide and immune complexes is a monocyte prothrombinase
1982
Arrestin Function in Inactivation of G Protein-Coupled Receptor Rhodopsin in Vivo
1993 Science
Secretory products of macrophages.
1987 Standout
Collagenase Production by Endotoxin-Activated Macrophages
1974
Role of βγ Subunits of G Proteins in Targeting the β-Adrenergic Receptor Kinase to Membrane-Bound Receptors
1992 StandoutScienceNobel
Helper T‐cell identity and evolution of differential transcriptomes and epigenomes
2013
Autoantigens targeted in systemic lupus erythematosus are clustered in two populations of surface structures on apoptotic keratinocytes.
1994
Primary and secondary structure of bovine retinal S antigen (48-kDa protein).
1987
Tolerance, the thymus, and suppressor T cells.
1977
Interleukin 1: An Immunological Perspective
1985
Tumour necrosis factor as immunomodulator and mediator of monocyte cytotoxicity induced by itself, γ-interferon and interleukin-1
1986 Nature
Intrathymic and Extrathymic T Cell Maturation
1978
The Basis for the Immunoregulatory Role of Macrophages and Other Accessory Cells
1987 Science
Mitogenic stimulation of murine spleen cells: relation to susceptibility to Salmonella infection
1977
Preparation of lymphocyte-activating factor from continuous murine macrophage cell lines
1977
Medullary Thymic Epithelium: A Mosaic of Epithelial “Self”?
1998
Differentiation of Effector CD4 T Cell Populations
2010 Standout
β-Arrestin: a Protein that Regulates β-adrenergic Receptor Function
1990 StandoutScienceNobel
Pig interleukin 1. Purification of two immunologically different leukocyte proteins that cause cartilage resorption, lymphocyte activation, and fever.
1985
A novel leader peptide which allows efficient secretion of a fragment of human interleukin 1 beta in Saccharomyces cerevisiae.
1987
Receptor-Induced Conformation Change of the Immunosuppressant Cyclosporin A
1991 StandoutScienceNobel
Interleukin-2: Inception, Impact, and Implications
1988 StandoutScience
Works of Igal Gery being referenced
Neural Adrenergic/Cyclic AMP Regulation of the Immunoglobulin E Receptor α-Subunit Expression in the Mammalian Pinealocyte
2007
Suppressor of Cytokine Signaling 3 Regulates Proliferation and Activation of T-helper Cells
2003
TH17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT1
2007
Immunocytochemical evidence of molecular photoreceptor markers in cerebellar medulloblastomas
1987
Interleukin 1 is more than an interleukin
1982
TREATMENT OF INTRAOCULAR INFLAMMATORY DISEASE WITH CYCLOSPORIN A
1983
The reactivity of spleen cells from malarious rats to non-specific mitogens.
1976
Potentiation of Cultured Mouse Thymocyte Responses by Factors Released by Peripheral Leucocytes
1971
Potentiation of the T lymphocyte response to mitogens
1974
Production of intra- and extracellular interleukin-1 (IL-1) by human monocytes
1984
ROLE OF THE THYMUS IN TOLERANCE
1966
Immunocytochemical demonstration of retinal S-antigen in the pineal organ of four mammalian species
1985
Relationship between production and release of lymphocyte-activating factor (interleukin 1) by murine macrophages
1981
Suppressive Effects of in Vivo Immunization on PHA Responses in Vitro
1974
Immunohistochemical Analysis of Experimental Autoimmune Uveoretinitis (Eau) Induced by Interphotoreceptor Retinoid-Binding Protein (Irbp) in the Rat
1987
Silica-stimulated monocytes release fibroblast proliferation factors identical to interleukin 1. A potential role for interleukin 1 in the pathogenesis of silicosis.
1984
Recognition of peptides that are immunopathogenic but cryptic. Mechanisms that allow lymphocytes sensitized against cryptic peptides to initiate pathogenic autoimmune processes.
1991
Expression of ocular autoantigens in the mouse thymus
1998
Thymic expression of autoantigens correlates with resistance to autoimmune disease.
1997
POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS
1972 Standout
T cell lines mediating experimental autoimmune uveoretinitis (EAU) in the rat.
1986
Cellular Immune Responsiveness of Uveitis Patients to Retinal S-Antigen
1980
POTENTIATION OF THE T-LYMPHOCYTE RESPONSE TO MITOGENS
1972
Role of the thymus in tolerance. V. Suppressive effect of treatment with nonaggregated and aggregated bovine gamma-globulin on specific immune responses in normal adult rats.
1967
Role of the thymus in tolerance. VII. Distribution of nonaggregated and heat-aggregated bovine gamma globulin in lymphoid organs of normal newborn and adult rats.
1968
Stimulation of B-lymphocytes by endotoxin. Reactions of thymus-deprived mice and karyotypic analysis of dividing cells in mice bearing T 6 T 6 thymus grafts.
1972
Suppressors of Cytokine Signaling Proteins Are Differentially Expressed in Th1 and Th2 Cells: Implications for Th Cell Lineage Commitment and Maintenance
2002
Pinealocyte Projections into the Mammalian Brain Revealed with S-Antigen Antiserum
1986 Science
Phenotype Switching by Inflammation-Inducing Polarized Th17 Cells, but Not by Th1 Cells
2008
Cyclosporin A: Alterations of the Cellular Immune Response in S-Antigen-Induced Experimental Autoimmune Uveitis
1983