Standout Papers

The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and pro... 1997 2026 2006 2016 1.2k
  1. The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals. (2000)
    Yasuko Kureishi, Zhengyu Luo et al. Nature Medicine
  2. Role of Akt Signaling in Vascular Homeostasis and Angiogenesis (2002)
    Ichiro Shiojima, Kenneth Walsh Circulation Research
  3. Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure (2005)
    Ichiro Shiojima Journal of Clinical Investigation
  4. Oxidative stress activates extracellular signal-regulated kinases through Src and Ras in cultured cardiac myocytes of neonatal rats. (1997)
    Ryuichi Aikawa, Issei Komuro et al. Journal of Clinical Investigation
  5. Adiponectin-mediated modulation of hypertrophic signals in the heart (2004)
    Rei Shibata, Noriyuki Ouchi et al. Nature Medicine

Immediate Impact

8 by Nobel laureates 9 from Science/Nature 68 standout
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Citing Papers

Clinical course and risk factors for mortality of adult inpatients with COVID-19 in Wuhan, China: a retrospective cohort study
2020 Standout
AKT/PKB Signaling: Navigating the Network
2017 Standout
14 intermediate papers

Works of Ichiro Shiojima being referenced

Pathological angiogenesis is induced by sustained Akt signaling and inhibited by rapamycin
2006
Disruption of coordinated cardiac hypertrophy and angiogenesis contributes to the transition to heart failure
2005 Standout
and 10 more

Author Peers

Author Last Decade Papers Cites
Ichiro Shiojima 4338 7246 2170 166 11.9k
Ronglih Liao 4261 6871 2408 204 12.2k
Yunzeng Zou 5102 6947 1753 305 12.7k
Julie R. McMullen 4824 6420 1396 130 11.2k
Sumanth D. Prabhu 5341 5002 2238 190 11.6k
Frank J. Giordano 2681 6645 2176 85 11.4k
Yasushi Fujio 2777 5882 1451 177 11.4k
Motoaki Sano 3066 4567 2518 222 10.0k
Mark A. Sussman 3818 7168 2970 189 11.7k
Evangelos D. Michelakis 4872 7428 1650 145 16.6k
Richard N. Kitsis 2967 7240 1236 111 11.3k

All Works

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2026