Standout Papers
- The Caenorhabditis elegans unc-13 gene product is a phospholipid-dependent high-affinity phorbol ester receptor (1992)
- Surface Display of Proteins on Bacteriophage λ Heads (1996)
- A phorbol ester/diacylglycerol-binding protein encoded by the unc-13 gene of Caenorhabditis elegans. (1991)
- A selective λ phage cloning vector with automatic excision of the insert in a plasmid (1992)
- Caenorhabditis elegansのunc‐13遺伝子がコードするホルボールエステル/ジアシルグリセロール結合蛋白質 (1991)
Citation Impact
Citing Papers
Jinx , an MCMV susceptibility phenotype caused by disruption of Unc13d : a mouse model of type 3 familial hemophagocytic lymphohistiocytosis
2007 StandoutNobel
An Extensive Class of Small RNAs in Caenorhabditis elegans
2001 StandoutScienceNobel
Munc13-4 Is Essential for Cytolytic Granules Fusion and Is Mutated in a Form of Familial Hemophagocytic Lymphohistiocytosis (FHL3)
2003
Synaptotagmin I: A major Ca2+ sensor for transmitter release at a central synapse
1994 StandoutNobel
UNC-13 is required for synaptic vesicle fusion in C. elegans
1999
A post-docking role for active zone protein Rim
2001
CeMyoD accumulation defines the body wall muscle cell fate during C. elegans embryogenesis
1990 StandoutNobel
Essential role of mouse telomerase in highly proliferative organs
1998 StandoutNatureNobel
UNC-13 Interaction with Syntaxin Is Required for Synaptic Transmission
2005
MicroRNAs
2004 Standout
The X-ray crystal structure of neuronal Sec1 from squid sheds new light on the role of this protein in exocytosis
2000
Cloning of a novel gene in the human kidney homologous to rat munc13s: Its potential role in diabetic nephropathy
1998
Molecular determinants of presynaptic active zones
2000
Identification of the Minimal Protein Domain Required for Priming Activity of Munc13-1
2005
Solution structure of a cysteine rich domain of rat protein kinase C
1994
A molecular basis for familial hypertrophic cardiomyopathy: A β cardiac myosin heavy chain gene missense mutation
1990 Standout
Munc18-1 Promotes Large Dense-Core Vesicle Docking
2001 StandoutNobel
An open form of syntaxin bypasses the requirement for UNC-13 in vesicle priming
2001 Nature
Information content ofCaenorhabditis eleganssplice site sequences varies with intron length
1990
Opposing effects of phorbol esters on transmitter release and calcium currents at frog motor nerve endings
1997
Drosophila CAPS Is an Essential Gene that Regulates Dense-Core Vesicle Release and Synaptic Vesicle Fusion
2001
Inactivation of Conserved C. elegans Genes Engages Pathogen- and Xenobiotic-Associated Defenses
2012 StandoutNobel
Potent and specific genetic interference by double-stranded RNA in Caenorhabditis elegans
1998 StandoutNatureNobel
Drosophila Unc-13 is essential for synaptic transmission
1999
Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes
2000
Snares and munc18 in synaptic vesicle fusion
2002 StandoutNobel
Direct Interaction of the Rat unc-13 Homologue Munc13-1 with the N Terminus of Syntaxin
1997
Redundant Localization Mechanisms of RIM and ELKS inCaenorhabditis elegans
2005
The rde-1 Gene, RNA Interference, and Transposon Silencing in C. elegans
1999 StandoutNobel
Conservation of the sequence and temporal expression of let-7 heterochronic regulatory RNA
2000 StandoutNatureNobel
The Presynaptic Active Zone
2012 StandoutNobel
Calcium sensors in regulated exocytosis
1998
Physical and Functional Interactions of Doc2 and Munc13 in Ca2+-dependent Exocytotic Machinery
1997
The C. elegans heterochronic gene lin-4 encodes small RNAs with antisense complementarity to lin-14
1993 StandoutNobel
Food and metabolic signalling defects in a Caenorhabditis elegans serotonin-synthesis mutant
2000 StandoutNatureNobel
A Munc13/RIM/Rab3 tripartite complex: from priming to plasticity?
2005 StandoutNobel
The small GTP-binding protein Rab3A regulates a late step in synaptic vesicle fusion
1997 StandoutNatureNobel
The C. elegans genome sequencing project: a beginning
1992 StandoutNatureNobel
Synaptotagmin I functions as a calcium regulator of release probability
2001 StandoutNatureNobel
Mammalian Homologues of Caenorhabditis elegans unc-13 Gene Define Novel Family of C2-domain Proteins
1995 StandoutNobel
Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory genes
2003 StandoutNatureNobel
Defects in synaptic vesicle docking in unc-18 mutants
2003
Ca2+-dependent and -independent activities of neural and non-neural synaptotagmins
1995 StandoutNatureNobel
Munc13-1 Is a Presynaptic Phorbol Ester Receptor that Enhances Neurotransmitter Release
1998 StandoutNobel
Three-dimensional structure of the neuronal-Sec1–syntaxin 1a complex
2000 Nature
A dual-Ca2+-sensor model for neurotransmitter release in a central synapse
2007 StandoutNatureNobel
Posttranscriptional regulation of the heterochronic gene lin-14 by lin-4 mediates temporal pattern formation in C. elegans
1993 StandoutNobel
Structure of the first C2 domain of synaptotagmin I: A novel Ca2+/phospholipid-binding fold
1995 StandoutNobel
Characterization of the Cysteine-rich Region of the Caenorhabditiselegans Protein Unc-13 as a High Affinity Phorbol Ester Receptor
1995
Quantum dot ligands provide new insights into erbB/HER receptor–mediated signal transduction
2004
Revealing the world of RNA interference
2004 StandoutNatureNobel
Functional Interaction of the Active Zone Proteins Munc13-1 and RIM1 in Synaptic Vesicle Priming
2001
Caenorhabditis elegans mutants resistant to inhibitors of acetylcholinesterase.
1995
The 21-nucleotide let-7 RNA regulates developmental timing in Caenorhabditis elegans
2000 StandoutNatureNobel
Systematic analysis of genes required for synapse structure and function
2005 StandoutNatureNobel
RIM1α is required for presynaptic long-term potentiation
2002 StandoutNatureNobel
A conserved siRNA-degrading RNase negatively regulates RNA interference in C. elegans
2004 StandoutNatureNobel
Isolation of a Candidate Human Telomerase Catalytic Subunit Gene, Which Reveals Complex Splicing Patterns in Different Cell Types
1997
Visualizing secretion and synaptic transmission with pH-sensitive green fluorescent proteins
1998 StandoutNatureNobel
Serotonin Inhibition of Synaptic Transmission
1999
Munc13-4 Is a GTP-Rab27-binding Protein Regulating Dense Core Granule Secretion in Platelets
2004
The functions of animal microRNAs
2004 StandoutNatureNobel
The synaptic vesicle cycle: a cascade of protein–protein interactions
1995 StandoutNatureNobel
RIM1α forms a protein scaffold for regulating neurotransmitter release at the active zone
2002 StandoutNatureNobel
C. elegans phagocytosis and cell-migration protein CED-5 is similar to human DOCK180
1998 StandoutNatureNobel
Cast
2002
Synaptic transmission deficits in Caenorhabditis elegans synaptobrevin mutants.
1998
Zinc finger domains and phorbol ester pharmacophore. Analysis of binding to mutated form of protein kinase C zeta and the vav and c-raf proto-oncogene products
1994
The Caenorhabditis elegans gene lin-1 encodes an ETS-domain protein and defines a branch of the vulval induction pathway.
1995 StandoutNobel
Neurobiology of the Caenorhabditis elegans Genome
1998 Science
Cloning of the cDNA encoding the myosin heavy chain of a vertebrate cellular myosin.
1989
Synaptic Transmission Deficits inCaenorhabditis elegansSynaptobrevin Mutants
1998
A phorbol ester binding domain of protein kinase C gamma. Deletion analysis of the Cys2 domain defines a minimal 43-amino acid peptide.
1994
Export of protein from the endoplasmic reticulum is regulated by a diacylglycerol/phorbol ester binding protein.
1994
TheCaenorhabditis elegans unc-64Locus Encodes a Syntaxin That Interacts Genetically with Synaptobrevin
1998
Bruchpilot Promotes Active Zone Assembly, Ca 2+ Channel Clustering, and Vesicle Release
2006 StandoutScienceNobel
Genetically targeted cell disruption in Caenorhabditis elegans
1997 StandoutNobel
Protein Sorting by Transport Vesicles
1996 StandoutScienceNobel
Proper expression of myosin genes in transgenic nematodes.
1989 StandoutNobel
A single C2 domain from synaptotagmin I is sufficient for high affinity Ca2+/phospholipid binding.
1993 StandoutNobel
Rab3 reversibly recruits rabphilin to synaptic vesicles by a mechanism analogous to raf recruitment by ras.
1996 StandoutNobel
A genetic selection for Caenorhabditis elegans synaptic transmission mutants.
1996
Calcium/Calmodulin-Dependent Protein Kinase II Regulates Caenorhabditis elegans Locomotion in Concert With a Go/Gq Signaling Network
2000
Membrane Fusion: Grappling with SNARE and SM Proteins
2009 StandoutScienceNobel
The Fluorescent Toolbox for Assessing Protein Location and Function
2006 StandoutScienceNobel
The Caenorhabditis elegans NK-2 class homeoprotein CEH-22 is involved in combinatorial activation of gene expression in pharyngeal muscle
1994 StandoutNobel
Synaptic Assembly of the Brain in the Absence of Neurotransmitter Secretion
2000 StandoutScienceNobel
Delineation of two functionally distinct domains of cytosolic phospholipase A2, a regulatory Ca(2+)-dependent lipid-binding domain and a Ca(2+)-independent catalytic domain.
1994
Works of Ichiro Maruyama being referenced
Caenorhabditis elegansのunc‐13遺伝子がコードするホルボールエステル/ジアシルグリセロール結合蛋白質
1991 StandoutNobel
cRACE: a simple method for identification of the 5′ end of mRNAs
1995
Activation of preformed EGF receptor dimers by ligand-induced rotation of the transmembrane domain11Edited by B. Holland
2001
ASB-1, a germline-specific isoform of mitochondrial ATP synthase b subunit, is required to maintain the rate of germline development in Caenorhabditis elegans
2006
A selective λ phage cloning vector with automatic excision of the insert in a plasmid
1992 StandoutNobel
Sequence analysis of the complete Caenorhabditis elegans myosin heavy chain gene family
1989
The Caenorhabditis elegans unc-13 gene product is a phospholipid-dependent high-affinity phorbol ester receptor
1992 StandoutNobel
Expression of Multiple UNC-13 Proteins in theCaenorhabditis elegansNervous System
2000
A phorbol ester/diacylglycerol-binding protein encoded by the unc-13 gene of Caenorhabditis elegans.
1991 StandoutNobel
Regulation of the UNC-18–Caenorhabditis elegansSyntaxin Complex by UNC-13
1999