Citation Impact
Citing Papers
Rapid protein fold determination using unassigned NMR data
2003 StandoutNobel
NMR structure reveals intramolecular regulation mechanism for pheromone binding and release
2001 StandoutNobel
Targeting of Cyclic AMP Degradation to β 2 -Adrenergic Receptors by β-Arrestins
2002 StandoutScienceNobel
Differential distribution of cAMP‐specific phosphodiesterase 7A mRNA in rat brain and peripheral organs
2001
Neuronal architecture of the antennal lobe in Drosophila melanogaster
1990
High biochemical selectivity of tadalafil, sildenafil and vardenafil for human phosphodiesterase 5A1 (PDE5) over PDE11A4 suggests the absence of PDE11A4 cross-reaction in patients
2004
Targeted Expression of Tetanus Toxin: A New Tool to Study the Neurobiology of Behavior**Dedicated to the memory of Heiner Niemann (1946–1999), without whose generosity the work here described would not have been possible.
2002
Deletion of phosphodiesterase 4D in mice shortens α2-adrenoceptor–mediated anesthesia, a behavioral correlate of emesis
2002
Comparative chemosensation from receptors to ecology
2006 Nature
Human immunodeficiency virus type 1–infected monocytic cells can destroy human neural cells after cell‐to‐cell adhesion
1992 StandoutNobel
Levamisole‐activated single‐channel currents from muscle of the nematode parasite Ascaris suum
1993
An Olfactory Sensory Map in the Fly Brain
2000 StandoutNobel
Cyclic nucleotide phosphodiesterase (PDE) superfamily: A new target for the development of specific therapeutic agents
2005 Standout
Expression of cGMP-binding cGMP-specific phosphodiesterase (PDE5) in mouse tissues and cell lines using an antibody against the enzyme amino-terminal domain
2001
Cyclic Nucleotide Phosphodiesterases: Molecular Regulation to Clinical Use
2006 Standout
Human Ca2+/calmodulin-dependent phosphodiesterase PDE1A: novel splice variants, their specific expression, genomic organization, and chromosomal localization
2001
Dual Expression and Differential Regulation of Phosphodiesterase 3A and Phosphodiesterase 3B in Human Vascular Smooth Muscle: Implications for Phosphodiesterase 3 Inhibition in Human Cardiovascular Tissues
2000
Neuropeptides, amines and amino acids in an elementary insect ganglion: Functional and chemical anatomy of the unfused abdominal ganglion
1996
Central Olfactory Pathways in Mosquitoes and Other Insects
2007
Neuroblast ablation in Drosophila P[GAL4] lines reveals origins of olfactory interneurons
1997
Cushing's syndrome
2015 Standout
mRNA expression patterns of the cGMP‐hydrolyzing phosphodiesterases types 2, 5, and 9 during development of the rat brain
2003
Identification of rat cyclic nucleotide phosphodiesterase 11A (PDE11A)
2001
Acetylcholine receptor molecules of the nematode Caenorhabditis elegans
1993
Cloning of a cDNA encoding a putative nicotinic acetylcholine receptor subunit of the human filarial parasite Onchocerca volvulus
1994
cAMP Is a Ligand for the Tandem GAF Domain of Human Phosphodiesterase 10 and cGMP for the Tandem GAF Domain of Phosphodiesterase 11
2005
Chronic inhibition of cyclic GMP phosphodiesterase 5A prevents and reverses cardiac hypertrophy
2005 Standout
The physiology and pharmacology of neuromuscular transmission in the nematode parasite,Ascaris suum
1991
Characterisation of cyclic nucleotide phosphodiesterase isoforms in the media layer of the main pulmonary artery
2002
Differential expression and localization of calmodulin‐dependent phosphodiesterase genes during ontogenesis of chick dorsal root ganglion
2002
Structure of the GAF domain, a ubiquitous signaling motif and a new class of cyclic GMP receptor
2000
VEGF-induced HUVEC migration and proliferation are decreased by PDE2 and PDE4 inhibitors
2003
Machine learning for molecular and materials science
2018 StandoutNature
Properties and Functions of GAF Domains in Cyclic Nucleotide Phosphodiesterases and Other Proteins
2004
A Spatial Map of Olfactory Receptor Expression in the Drosophila Antenna
1999 StandoutNobel
Information Coding in the Vertebrate Olfactory System
1996 StandoutNobel
Mechanism of Transducin Activation of Frog Rod Photoreceptor Phosphodiesterase
2000
Mechanisms of action of PDE5 inhibition in erectile dysfunction
2004
A single population of olfactory sensory neurons mediates an innate avoidance behaviour in Drosophila
2004 StandoutNatureNobel
Actions of neurotoxins (bungarotoxins, neosurugatoxin and lophotoxins) on insect and nematode nicotinic acetylcholine receptors
1995
Mice Deficient in Golf Are Anosmic
1998 StandoutNobel
Olfactory activation patterns in the antennal lobe of the sphinx moth, Manduca sexta
2003
Two-Photon Calcium Imaging Reveals an Odor-Evoked Map of Activity in the Fly Brain
2003 StandoutNobel
Multiple factors shape development of olfactory glomeruli: Insights from an insect model system
1996
Anatomy of antenno-cerebral pathways in the brain of the sphinx moth Manduca sexta
1988
Cyclic nucleotide research — still expanding after half a century
2002 Standout
Cilostazol (Pletal®): A Dual Inhibitor of Cyclic Nucleotide Phosphodiesterase Type 3 and Adenosine Uptake
2001
Carbon-dioxide sensing structures in terrestrial arthropods
1999
cGMP-Dependent Protein Kinases and cGMP Phosphodiesterases in Nitric Oxide and cGMP Action
2010 Standout
Odorant Receptors Govern the Formation of a Precise Topographic Map
1998 StandoutNobel
Cloning, Characterization, and Tissue Distribution of Mouse Phosphodiesterase 7A1
2000
Isolation and differential tissue distribution of two human cDNAs encoding PDE1 splice variants
2002
A Nobel for Smell
2004 StandoutNobel
Neuronal Synchrony: A Versatile Code for the Definition of Relations?
1999 Standout
Molecular Determinants for Cyclic Nucleotide Binding to the Regulatory Domains of Phosphodiesterase 2A
2004
Neuroanatomy of cells expressing clock genes inDrosophila: Transgenic manipulation of theperiod andtimeless genes to mark the perikarya of circadian pacemaker neurons and their projections
2000 StandoutNobel
Phosphodiesterases 4D and 7A Splice Variants in the Response of HUVEC Cells to TNF-α1
2000
The MicroRNA miR-1 Regulates a MEF-2-Dependent Retrograde Signal at Neuromuscular Junctions
2008 StandoutNobel
3′,5′-Cyclic nucleotide phosphodiesterase 11A: localization in human tissues
2005
Distribution in the central nervous system of Aplysia of afferent fibers arising from cell bodies located in the periphery
1995
Crystal structure of phosphodiesterase 4D and inhibitor complex1
2002
Effect of sildenafil on cyclic nucleotide phosphodiesterase activity, vascular tone and calcium signaling in rat pulmonary artery
2003
Effects of Iron Supplementation and Depletion on Hypoxic Pulmonary Hypertension
2009 StandoutNobel
Cyclic nucleotide phosphodiesterases and their role in immunomodulatory responses: Advances in the development of specific phosphodiesterase inhibitors
2004
A Multigene Family Encoding a Diverse Array of Putative Pheromone Receptors in Mammals
1997 StandoutNobel
A Chemosensory Gene Family Encoding Candidate Gustatory and Olfactory Receptors in Drosophila
2001 StandoutNobel
Cloning and sequence analysis of the candidate nicotinic acetylcholine receptor alpha subunit gene tar-1 from Trichostrongylus colubriformis
1996
Increased Activity of cGMP-Specific Phosphodiesterase (PDE5) Contributes to Resistance to Atrial Natriuretic Peptide Natriuresis in the Pregnant Rat
2004
Spatial Representation of the Glomerular Map in the Drosophila Protocerebrum
2002 StandoutNobel
Pungent agents from Szechuan peppers excite sensory neurons by inhibiting two-pore potassium channels
2008 StandoutNobel
NMR structure of the unliganded Bombyx mori pheromone‐binding protein at physiological pH
2002 StandoutNobel
Control of Male Sexual Behavior and Sexual Orientation in Drosophila by the fruitless Gene
1996 StandoutNobel
The organization of the chemosensory system in Drosophila melanogaster: a rewiew
1994
A cAMP-specific phosphodiesterase (PDE8B) that is mutated in adrenal hyperplasia is expressed widely in human and mouse tissues: a novel PDE8B isoform in human adrenal cortex
2008
An Olfactory Sensory Map Develops in the Absence of Normal Projection Neurons or GABAergic Interneurons
1998 StandoutNobel
Contributions from Caenorhabditis elegans functional genetics to antiparasitic drug target identification and validation: Nicotinic acetylcholine receptors, a case study
2006
Application of text mining in the biomedical domain
2015
Genomic organization of the human phosphodiesterase PDE11A gene
2001
The increase in pulmonary arterial pressure caused by hypoxia depends on iron status
2008 StandoutNobel
Isolation and Characterization of Two Novel Phosphodiesterase PDE11A Variants Showing Unique Structure and Tissue-specific Expression
2000
Phosphodiesterase inhibitors are neuroprotective to cultured spinal motor neurons
2002
Synaptic organization and development of the antennal lobe in insects
1993
Crystal Structures of the Catalytic Domain of Phosphodiesterase 4B Complexed with AMP, 8-Br-AMP, and Rolipram
2004
The Molecular Architecture of Odor and Pheromone Sensing in Mammals
2000 StandoutNobel
A Map of Pheromone Receptor Activation in the Mammalian Brain
1999 StandoutNobel
Species differences in the localization of cGMP‐producing and NO‐responsive elements in the mouse and rat hippocampus using cGMP immunocytochemistry
2004
Discrimination of pheromonal cues in fish: emerging parallels with insects
1998
Systems Approaches to Biological Rhythms in Drosophila
2005 StandoutNobel
Target sites of anthelmintics
1997
Cyclic GMP-Hydrolyzing Phosphodiesterases
2008
Dual Expression and Differential Regulation of Phosphodiesterase 3A and Phosphodiesterase 3B in Human Vascular Smooth Muscle: Implications for Phosphodiesterase 3 Inhibition in Human Cardiovascular Tissues
2000
Immunocytochemistry of GABA in the antennal lobes of the sphinx moth Manduca sexta
1986
Coincident Stimulation With Pheromone Components Improves Temporal Pattern Resolution in Central Olfactory Neurons
1997
Role of Inhibition for Temporal and Spatial Odor Representation in Olfactory Output Neurons: A Calcium Imaging Study
2002
Representations of odours and odour mixtures visualized in the honeybee brain
1997 Nature
Tissue-Specific Inducible Expression of Antimicrobial Peptide Genes in Drosophila Surface Epithelia
2000 StandoutNobel
Expression of PDE11A in Normal and Malignant Human Tissues
2005
Cardiac phosphodiesterase 5 (cGMP‐specific) modulates β‐adrenergic signaling in vivo and is down‐regulated in heart failure
2001
Three-dimensional reconstruction of the antennal lobe inDrosophila melanogaster
1999
In Vivo Assessment of Local Phosphodiesterase Activity Using Tailored Cyclic Nucleotide–Gated Channels as Camp Sensors
2001
Pulmonary Arterial Hypertension
2006
Deletion of CASK in mice is lethal and impairs synaptic function
2007 StandoutNobel
An anthelmintic compound, nafuredin, shows selective inhibition of complex I in helminth mitochondria
2000 StandoutNobel
T cell activation up-regulates cyclic nucleotide phosphodiesterases 8A1 and 7A3
2001
Olfaction in Lepidoptera
1995
Cholinergic receptor mutants of the nematode Caenorhabditis elegans
1987
Independent Photoreceptive Circadian Clocks Throughout Drosophila
1997 StandoutScienceNobel
Distinct Mechanisms for Synchronization and Temporal Patterning of Odor-Encoding Neural Assemblies
1996 Science
Phosphodiesterase 11 (PDE11) regulation of spermatozoa physiology
2005
Midgut-specific immune molecules are produced by the blood-sucking insect Stomoxys calcitrans
1997
Cloning and characterization of two splice variants of human phosphodiesterase 11A
2000
A Simplified Preparation for Relating Cellular Events to Behavior: Contribution of LE and Unidentified Siphon Sensory Neurons to Mediation and Habituation of theAplysiaGill- and Siphon-Withdrawal Reflex
1997 StandoutNobel
Potential role of phosphodiesterase 7 in human T cell function: comparative effects of two phosphodiesterase inhibitors
2002
Diastereoselective Allylation of Carbonyl Compounds and Imines: Application to the Synthesis of Natural Products
2013 Standout
Cyclic nucleotide phosphodiesterases in Drosophila melanogaster
2005
Association of β-catenin with the α-subunit of neuronal large-conductance Ca 2+ -activated K+ channels
2003
MECHANISMS OF OLFACTORY DISCRIMINATION: Converging Evidence for Common Principles Across Phyla
1997
The GABAergic nervous system of Caenorhabditis elegans
1993 StandoutNatureNobel
Ubiquitous expression of phosphodiesterase 7A in human proinflammatory and immune cells
2003
Abnormalities of Male-Specific FRU Protein and Serotonin Expression in the CNS offruitlessMutants inDrosophila
2001 StandoutNobel
Functional analysis of fruitless gene expression by transgenic manipulations of Drosophila courtship
2005 StandoutNobel
Hydrolysis of cyclic GMP in rat peritoneal macrophages.
2002
Phosphodiesterase Type 5 as a Target for the Treatment of Hypoxia-Induced Pulmonary Hypertension
2003
Extended Reproductive Roles of the fruitless Gene in Drosophila melanogaster Revealed by Behavioral Analysis of New fru Mutants
1997 StandoutNobel
The Mating of a Fly
1994 StandoutScienceNobel
Overview of PDEs and Their Regulation
2007
Phylogenetic Perspectives in Innate Immunity
1999 StandoutScienceNobel
Crystal structure of the tandem GAF domains from a cyanobacterial adenylyl cyclase: Modes of ligand binding and dimerization
2005
Analysis of chemical signals by nervous systems.
1995
Genetic Feminization of Brain Structures and Changed Sexual Orientation in Male Drosophila
1995 Science
Central Projections of the Maxillary and Antennal Nerves in the Mosquito Aedes Aegypti
1997
CO2 sensitive receptors on labial palps ofRhodogastria moths (Lepidoptera: Arctiidae): physiology, fine structure and central projection
1986
Dysiherbaine: A New Neurotoxic Amino Acid from the Micronesian Marine Sponge Dysidea herbacea
1997
Evidence for neurotoxic activity of tat from human immunodeficiency virus type 1
1991
Caenorhabditis elegansLevamisole Resistance Geneslev-1,unc-29, andunc-38Encode Functional Nicotinic Acetylcholine Receptor Subunits
1997 StandoutNobel
Multiple Binding Modes of Inhibitors to Carbonic Anhydrases: How to Design Specific Drugs Targeting 15 Different Isoforms?
2012 Standout
Works of Ian Harrow being referenced
Towards Virtual Knowledge Broker services for semantic integration of life science literature and data sources
2012
Local interneurons and information processing in the olfactory glomeruli of the moth Manduca sexta
1993
Actions of potent cholinergic anthelmintics (morantel, pyrantel and levamisole) on an identified insect neurone reveal pharmacological differences between nematode and insect acetylcholine receptors
1988
Properties of BK Ca Channels Formed by Bicistronic Expression of hSlo ? and ?1-4 Subunits in HEK293 Cells
2003
Distinct Projections of Two Populations of Olfactory Receptor Axons in the Antennal Lobe of the Sphinx Moth Manduca sexta
1995
Cockroach Giant Interneurones Stained by Cobalt-Backfilling of Dissected Axons
1980
An accessory olfactory pathway in Lepidoptera: the labial pit organ and its central projections in Manduca sexta and certain other sphinx moths and silk moths
1986
Nereistoxin: Actions on a Cns Acetylcholine Receptor/ion Channel in the CockroachPeriplaneta Americana
1985
α-Bungarotoxin Blocks Excitatory Synaptic Transmission Between Cercal Sensory Neurones and Giant Interneurone 2 of the Cockroach,Periplaneta Americana
1983
Molecular cloning and characterization of a distinct human phosphodiesterase gene family: PDE11A
2000
Mode of action of the anthelmintics morantel, pyrantel and levamisole on muscle cell membrane of the nematode Ascaris suum
1985
Ouabain-sensitive Na+/K+-ATPase activity in the reservoir zone of the midgut of Stomoxys calcitrans (diptera: muscidae)
1994