Citation Impact
Citing Papers
Host Defenses against Copper Toxicity
1990
The iron-sulfur clusters of dehydratases are primary intracellular targets of copper toxicity
2009
Nrf1 and Nrf2 Play Distinct Roles in Activation of Antioxidant Response Element-dependent Genes
2008
Comparative Genomics Analysis of the Metallomes
2012
The Ubiquitin Proteasome System in Neurodegenerative Diseases
2003 StandoutNobel
Wilson disease and canine copper toxicosis
1998
Copper-associated liver disease in childhood
1995
Tyrosinase inhibitors from natural and synthetic sources: structure, inhibition mechanism and perspective for the future
2005
Alterations in hepatocyte lysosomes in experimental hepatic copper overload in rats
1993
Differentially expressed genes in sporadic amyotrophic lateral sclerosis spinal cords – screening by molecular indexing and subsequent cDNA microarray analysis
2002
Isolation of cDNA encoding transcription factor Sp1 and functional analysis of the DNA binding domain
1987 Standout
Effects of copper on mammalian cell components
1989
Copper toxicity, oxidative stress, and antioxidant nutrients
2003 Standout
Type I iodothyronine deiodinase is a selenocysteine-containing enzyme
1991 StandoutNature
Metallothioneins: new functional and structural insights
2000
Extracellular metallothionein effects on lymphocyte activities
1990
Study on potential antitumor mechanism of a novel Schiff Base copper(II) complex: Synthesis, crystal structure, DNA binding, cytotoxicity and apoptosis induction activity
2011
Kashin–Beck Osteoarthropathy in Rural Tibet in Relation to Selenium and Iodine Status
1998 Standout
Combined analysis of hypoxia-inducible factor 1 alpha and metallothionein indicates an aggressive subtype of colorectal carcinoma
2009
The Function of Zinc Metallothionein: A Link between Cellular Zinc and Redox State
2000
The Role of Oxidative Stress in the Pathogenesis of Age-Related Macular Degeneration
2000 Standout
1H, 13C‐NMR and X‐ray Absorption Studies of Copper(I) Glutathione Complexes
1996
Reducing the Environmental Sensitivity of Yellow Fluorescent Protein
2001 StandoutNobel
Direct evidence for inhibition of free radical formation from Cu(I) and hydrogen peroxide by glutathione and other potential ligands using the EPR spin-trapping technique
1992
Copper deficiency as an anti-cancer strategy.
2004
Zinc Metabolism in the Brain: Relevance to Human Neurodegenerative Disorders
1997
NMR Structure of the Sea Urchin (Strongylocentrotus purpuratus) Metallothionein MTA
1999 StandoutNobel
Metallothionein-induced suppression of cytotoxic T lymphocyte function: an important immunoregulatory control
1999
Novel method for in vivo hydroxyl radical measurement by microdialysis in fetal sheep brain in utero
2005
NMR Structure and Metal Interactions of the CopZ Copper Chaperone
1999 StandoutNobel
Chemistry and Biochemistry of Metallothionein
1987
Cu-free click cycloaddition reactions in chemical biology
2010 StandoutNobel
A Critical Overview of the Chemistry of Copper-Dependent Low Density Lipoprotein Oxidation: Roles of Lipid Hydroperoxides, α-Tocopherol, Thiols, and Ceruloplasmin
2001
Repertoires of Autophagy in the Pathogenesis of Ocular Diseases
2015 Standout
Metallothionein in Regeneration, Reproduction and Development
1987
Chronic vitamin E inadequacy and thermally treated oils affect the synthesis of hepatic metallothionein isoforms
2000
A role for extracellular metallothioneins in CNS injury and repair
2003
Roles of the metallothionein family of proteins in the central nervous system
2001
Obesity is associated with macrophage accumulation in adipose tissue
2003 Standout
Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans
2003 StandoutNature
A Common Mechanism of Cellular Death Induced by Bactericidal Antibiotics
2007 Standout
Metallothionein/disulfide interactions, oxidative stress, and the mobilization of cellular zinc
1995
Protein Sequence Editing of SKN-1A/Nrf1 by Peptide:N-Glycanase Controls Proteasome Gene Expression
2019 StandoutNobel
Defining the role of hypoxia-inducible factor 1 in cancer biology and therapeutics
2009 StandoutNobel
Effect of Age and Sex on Liver Damage Due to Excess Dietary Copper in Fischer 344 Rats
2000
Clara cell secretory protein deficiency increases oxidant stress response in conducting airways
1998
[44] Detection of metallothionein in brain
1991
Copper Control as an Antiangiogenic Anticancer Therapy: Lessons from Treating Wilson's Disease
2001
Cu and Cu-Based Nanoparticles: Synthesis and Applications in Catalysis
2016 Standout
Products of metal exchange reactions of metallothionein
1985
Structure of the metal clusters in rabbit liver metallothionein
1980
Phenotypic consequences of lung-specific inducible expression of FGF-3
2001 StandoutNobel
Pharmaceuticals, Hormones, and Other Organic Wastewater Contaminants in U.S. Streams, 1999−2000: A National Reconnaissance
2002 Standout
Immunochemical detection of metallothionein in specific epithelial cells of rat organs.
1982
Preferential binding of copper to the beta domain of metallothionein.
1984
Biochemistry of metallothionein
1988
Comparison of the NMR solution structure and the x-ray crystal structure of rat metallothionein-2.
1992 StandoutNobel
Characterization of metal centres in biological systems by X-ray absorption spectroscopy
1987
Signaling Recognition Events with Fluorescent Sensors and Switches
1997 Standout
Domain nature of metallothionein.
1982
Human hepatic metallothioneins
1974
Copper Active Sites in Biology
2014 Standout
Expression in transgenic mice of class I histocompatibility antigens controlled by the metallothionein promoter.
1989 StandoutNobel
The Role of Glutathione in Copper Metabolism and Toxicity
1989
Expression and regulation of brain metallothionein
1995
Lectins: Cell-Agglutinating and Sugar-Specific Proteins
1972 StandoutScience
Cooperative capture synthesis: yet another playground for copper-free click chemistry
2016 StandoutNobel
The effects of selenium depletion and repletion on the metabolism of thyroid hormones in the rat
1990
Isolation and characterization of a zinc finger polypeptide gene at the human chromosome 11 Wilms' tumor locus
1990 Standout
Thiolate ligands in metallothionein confer redox activity on zinc clusters
1998
Structural and Functional Aspects of Metal Sites in Biology
1996 Standout
Dialogue between E. coli free radical pathways and the mitochondria of C. elegans
2015 StandoutNobel
Protein-Carbohydrate Interaction
1968
The challenges of using a copper fluorescent sensor (CS1) to track intracellular distributions of copper in neuronal and glial cells
2012
Structure—Reactivity Relationships of Metallothionein, a Unique Metal-Binding Protein
1989
Structure of a Nickel Chaperone, HypA, from Helicobacter pylori Reveals Two Distinct Metal Binding Sites
2009
Preparation and cadmium-113 NMR studies of homogeneous reconstituted metallothionein: reaffirmation of the two-cluster arrangement of metals
1985
Present interpretation of the role of copper in Indian childhood cirrhosis
1996
Bioavailability of copper
1996
Transcriptional regulation of the mouse metallothionein-I gene by heavy metals.
1981
Copper Homeostasis and Neurodegenerative Disorders (Alzheimer's, Prion, and Parkinson's Diseases and Amyotrophic Lateral Sclerosis)
2006 Standout
Cellular response of antioxidant metalloproteins in Cu/Zn SOD transgenic mice exposed to hyperoxia
2001
Gene Expression Profile in Skeletal Muscle of Type 2 Diabetes and the Effect of Insulin Treatment
2002
Biosynthesis of cadmium sulphide quantum semiconductor crystallites
1989 StandoutNatureNobel
Cytochemical Demonstration of Oxidative Damage in Alzheimer Disease by Immunochemical Enhancement of the Carbonyl Reaction with 2,4-Dinitrophenylhydrazine
1998
Hydrogenases
2014 Standout
Studies on the gamma-glutamyl Cu-binding peptide from Schizosaccharomyces pombe.
1988
Comparison of the solution conformations of human [Zn7]-metallothionein-2 and [Cd7]-metallothionein-2 using nuclear magnetic resonance spectroscopy
1992 StandoutNobel
Role of metallothionein in nitric oxide signaling as revealed by a green fluorescent fusion protein
2000
Intracellular Copper Does Not Catalyze the Formation of Oxidative DNA Damage in Escherichia coli
2006
α-Tocopherol Induces Oxidative Damage to DNA in the Presence of Copper(II) Ions
1998
Fluorescent Sensors for Measuring Metal Ions in Living Systems
2014 Standout
Role of copper in Indian childhood cirrhosis
1998
The elusive function of metallothioneins
1998
Bioinorganic Chemistry of Alzheimer’s Disease
2012
Copper induces cell death by targeting lipoylated TCA cycle proteins
2022 StandoutScience
Environmental Implications of Hydroxyl Radicals (•OH)
2015 Standout
Fluorescent Sensors for Zn2+Based on a Fluorescein Platform: Synthesis, Properties and Intracellular Distribution
2001 StandoutNobel
Toxicological Significance of Metallothionein
1987
Coordinated reduction of genes of oxidative metabolism in humans with insulin resistance and diabetes: Potential role ofPGC1andNRF1
2003 Standout
Measurement of zinc in hepatocytes by using a fluorescent probe, zinquin: relationship to metallothionein and intracellular zinc
1994
Aqueous-Phase Synthesis of Copper Nanoparticles Using Organic Nanoparticles: Application of Assembly in Detection of Cr3+
2014
Copper chelation in cancer therapy using tetrathiomolybdate: an evolving paradigm
2009
Synthesis, crystal structure, DNA-binding properties, cytotoxic and antioxidation activities of several ternary copper(II) complexes with a new reduced Schiff base ligand
2012
Effects of Dietary Copper, Cadmium, Iron, Molybdenum and Manganese on Selenium Utilization by the Rat
1986
Mechanisms Whereby Mononuclear Copper Proteins Functionalize Organic Substrates
1996 Standout
Reactive Oxygen Species (ROS)-Based Nanomedicine
2019 Standout
CpG-rich islands and the function of DNA methylation
1986 StandoutNature
Obesity is associated with macrophage accumulation in adipose tissue
2003 Standout
Fluorescent Chemosensors Based on Spiroring-Opening of Xanthenes and Related Derivatives
2011 Standout
EXAFS study of the zinc-binding sites in the protein transcription factor IIIA
1986 Nature
Liver copper storage and transport during development: implications for cytotoxicity
1996
Evidence from Extended X-ray Absorption Fine Structure and Site-specific Mutagenesis for Zinc Fingers in UvrA Protein of Escherichia coli
1989 StandoutNobel
The Leucine Zipper: A Hypothetical Structure Common to a New Class of DNA Binding Proteins
1988 StandoutScience
Metallic implant biomaterials
2014 Standout
Advances in Copper Complexes as Anticancer Agents
2013 Standout
Metal-specific synthesis of two metallothioneins and gamma-glutamyl peptides in Candida glabrata.
1988
Candida glabrata Metallothioneins
1989
Long term survival in Indian childhood cirrhosis treated with D-penicillamine.
1996
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
GENETIC MODELS OF OBESITY AND ENERGY BALANCE IN THE MOUSE
2000
Copper-related diseases: From chemistry to molecular pathology
2009
Copper Proteins and Copper Enzymes
1980
Longevity and heavy metal resistance in daf‐2 and age‐1 long‐lived mutants of Caenorhabditis elegans
2001
The novel metallothionein genes of Caenorhabditis elegans. Structural organization and inducible, cell-specific expression.
1993 StandoutNobel
Metallothionein III is expressed in neurons that sequester zinc in synaptic vesicles
1994
Novel Copper(II) Complex ofN-Propyl-norfloxacin and 1,10-Phenanthroline with Enhanced Antileukemic and DNA Nuclease Activities
2008
Metals in Neurobiology: Probing Their Chemistry and Biology with Molecular Imaging
2008 Standout
ZINC AND BRAIN INJURY
1998
Acquired chondronecrosis.
1990
The natural polyamine spermine functions directly as a free radical scavenger
1998 Standout
Works of I. Bremner being referenced
Oxygen free radicals and metallothionein
1993
Metallothionein in Blood, Bile and Urine
1987
Metallothionein immunoreactivity in the liver and kidney of copper injected rats
1989
Metallothionein and the Trace Minerals
1990
Copper and zinc metabolism in health and disease: speciation and interactions
1995
Effects of Changes in Dietary Zinc, Copper and Selenium Supply and of Endotoxin Administration on Metallothionein I Concentrations in Blood Cells and Urine in the Rat
1987
Effect of zinc, copper and glucocorticoids on metallothionein levels of cultured neurons and astrocytes from rat brain
1994
A convenient method for the treatment of chronic copper poisoning in sheep using subcutaneous ammonium tetrathiomolybdate
1988
The protective role of metallothionein in copper overload: I. Differential distribution of immunoreactive metallothionein in copper-loaded rat liver and kidney
1991
Stimulation of Peroxidation in Rat Liver Microsomes by (Copper, Zinc)-Metallothioneins
1987
Nutritional and Physiological Significance of Metallothionein
1987
The protective role of metallothionein in copper-overload: II. Transport and excretion of immunoreactive MT-1 in blood, bile and urine of copper-loaded rats
1991
Generation of 5,5-Dimethyl-1-pyrrolineN-Oxide Hydroxyl and Scavenger Radical Adducts from Copper/H2O2Mixtures: Effects of Metal Ion Chelation and the Search for High-Valent Metal–Oxygen Intermediates
1995
Manifestations of copper excess
1998
EXAFS Studies of Metallothionein
1987
Urinary excretion of metallothionein-I and its degradation product in rats treated with cadmium, copper, zinc or mercury
1989
[4] Nutritional and physiologic significance of metallothionein
1991
Interactions between metallothionein and trace elements.
1987
Structural study of the copper and zinc sites in metallothioneins by using extended X-ray-absorption fine structure
1986
Absorption, Transport and Distribution of Copper
1980
Studies on the appearance of a hepatic copper-binding protein in normal and zinc-deficient rats
1976
Effects of dietary copper supplementation of rats on the occurrence of metallothionein-I in liver and its secretion into blood, bile and urine
1986
Isolation of (copper, zinc-) thioneins from pig liver
1976
The effects of age, sex, and zinc status on the accumulation of (copper, zinc)-metallothionein in rat kidneys
1981
Biliary excretion of metallothionein and a possible degradation product in rats injected with copper and zinc
1984
Isolation of (copper, zinc)-thioneins from the livers of copper-injected rats
1976
Copper and molybdenum absorption by rats given ammonium tetrathiomolybdate
1981
Studies on the Induction of a Low-Molecular-Weight Zinc-Binding Protein in Rat Liver
1973
Involvement of Metallothionein in the Hepatic Metabolism of Copper
1987
Obesity and hyperleptinemia in metallothionein (-I and -II) null mice
1998
Effect of zinc status of rats on the synthesis and degradation of copper-induced metallothioneins
1978
Effects of molybdate, sulfide, and tetrathiomolybdate on copper metabolism in rats
1981
Copper metabolism in rats given di- or trithiomolybdates
1982
Autophagy and apoptosis in liver during the prehaemolytic phase of chronic copper poisoning in sheep
1979
Nature of the cadmium sites in rat liver metallothionein 1 from cadmium K-edge EXAFS
1985
Protective effect of zinc supplementation against copper toxicosis in sheep
1976
Research communication copper-1,10-phenanthroline induces internucleosomal DNA fragmentation in HepG2 cells, resulting from direct oxidation by the hydroxyl radical
1996
Metallothionein-I in the plasma and liver of neonatal rats
1984
[66] Metallothionein and copper metabolism in liver
1991
Investigation of the structure of metallothioneins by proton nuclear magnetic resonance spectroscopy
1980
Distribution of copper and zinc in the liver of the developing sheep foetus
1977
Studies on the metabolism of rat liver copper-metallothionein
1985
Development of a radioimmunoassay for rat liver metallothionein-I and its application to the analysis of rat plasma and kidneys
1983
Intestinal metallothionein and the mutual antagonism between copper and zinc in the rat
1979
Metabolism of 35S-labelled copper-, zinc- and cadmium-thionein in the rat
1978
Effects of dietary molybdenum and sulphur on the distribution of copper in plasma and kidneys of sheep
1978
The accretion of copper and of zinc by the foetuses of prolific ewes
1978
Measurement of Plasma Metallothionein-I in the Assessment of the Zinc Status of Zinc-Deficient and Stressed Rats
1984
The relationship between the zinc status of pigs and the occurrence of copper- and Zn-binding proteins in liver
1976
A sequential study of the skeletal abnormalities which develop in rats given a small dietary supplement of ammonium tetrathiomolybdate
1980
Hepatic copper–and zinc-binding proteins in ruminants
1974
A Mannan Elaborated by a Scarcina species.
1965
INCREASED HEPATIC COPPER CONCENTRATION IN INDIAN CHILDHOOD CIRRHOSIS
1979
The induction of metallothionein in rat liver by zinc injection and restriction of food intake
1975
Species differences in the occurrence of copper-metallothionein in the particulate fractions of the liver of copper-loaded animals
1984