Citation Impact
Citing Papers
High-Throughput Mapping of a Dynamic Signaling Network in Mammalian Cells
2005 StandoutScience
Highly specific in vivo tumor targeting by monovalent and divalent forms of 741F8 anti-c-erbB-2 single-chain Fv.
1993
Single-Chain Antibody-Mediated Intracellular Retention of ErbB-2 Impairs Neu Differentiation Factor and Epidermal Growth Factor Signaling
1995
Untangling the ErbB signalling network
2001 Standout
Lysosomal Targeting of Epidermal Growth Factor Receptors via a Kinase-dependent Pathway Is Mediated by the Receptor Carboxyl-terminal Residues 1022-1123
1996
Proposed treatment guidelines for HER2-positive metastatic breast cancer in Europe
2001
Concordance Between Central and Local Laboratory HER2 Testing from a Community-Based Clinical Study
2006
Herceptin: mechanisms of action and resistance
2005
Transforming growth factor-alpha expression is enhanced in human mammary epithelial cells transformed by an activated c-Ha-ras protooncogene but not by the c-neu protooncogene, and overexpression of the transforming growth factor-alpha complementary DNA leads to transformation.
1990
ErbB2 Potentiates Breast Tumor Proliferation through Modulation of p27Kip1-Cdk2 Complex Formation: Receptor Overexpression Does Not Determine Growth Dependency
2000
Recommendations for Human Epidermal Growth Factor Receptor 2 Testing in Breast Cancer: American Society of Clinical Oncology/College of American Pathologists Clinical Practice Guideline Update
2013 Standout
Heregulin Regulation of Akt/Protein Kinase B in Breast Cancer Cells
1999
Engineered receptors for soluble cellular communication and disease sensing
2024 StandoutNatureNobel
Growth regulation of human breast and ovarian tumor cells by heregulin: Evidence for the requirement of ErbB2 as a critical component in mediating heregulin responsiveness.
1996
The biology of erbB-2/nue/HER-2 and its role in cancer
1994
Killing cancer cells by targeted drug-carrying phage nanomedicines
2008
Lapatinib plus Capecitabine for HER2-Positive Advanced Breast Cancer
2006 Standout
The effects of the novel, reversible epidermal growth factor receptor/ErbB-2 tyrosine kinase inhibitor, GW2016, on the growth of human normal and tumor-derived cell lines in vitro and in vivo.
2001
Intracellular expression of single chain antibodies reverts ErbB-2 transformation.
1994
EGFR Antagonists in Cancer Treatment
2008 Standout
Cyclin E as a prognostic and predictive marker in breast cancer
2005
Cell polarity and epithelial oncogenesis
1991
Targeting by affinity–matured recombinant antibody fragments of an angiogenesis associated fibronectin isoform
1997 StandoutNobel
ErbB-2, the preferred heterodimerization partner of all ErbB receptors, is a mediator of lateral signaling
1997
Epidermal growth factor-related peptides and their receptors in human malignancies
1995 Standout
Cell Signaling by Receptor Tyrosine Kinases
2010 Standout
Mechanisms of Disease: understanding resistance to HER2-targeted therapy in human breast cancer
2006
De novo protein design. I. in search of stability and specificity
1999 StandoutNobel
Influence of Immunogenicity on the Long-Term Efficacy of Infliximab in Crohn's Disease
2003 Standout
Radiotherapy plus Cetuximab for Squamous-Cell Carcinoma of the Head and Neck
2006 Standout
Cetuximab Monotherapy and Cetuximab plus Irinotecan in Irinotecan-Refractory Metastatic Colorectal Cancer
2004 Standout
Structural Aspects of the Epidermal Growth Factor Receptor Required for Transmodulation of erbB-2/neu
1997
PHAST: A Fast Phage Search Tool
2011 Standout
Designed ankyrin repeat proteins are effective targeting elements for chimeric antigen receptors
2015
Genomic organization of major sperm protein genes and pseudogenes in the nematode Caenorhabditis elegans
1988 StandoutNobel
Erlotinib in Previously Treated Non–Small-Cell Lung Cancer
2005 Standout
Epithelial–mesenchymal transitions in tumour progression
2002 Standout
Trastuzumab — Mechanism of Action and Use in Clinical Practice
2007 Standout
Transformation of an established mouse mammary epithelial cell line following transfection with a human transforming growth factor alpha cDNA
1989
EGFR Mutation and Resistance of Non–Small-Cell Lung Cancer to Gefitinib
2005 Standout
Endocytosis and intracellular trafficking of ErbBs
2008
NEW EMBO MEMBERS' REVIEW: The ErbB signaling network: receptor heterodimerization in development and cancer
2000 Standout
Cancer immunotherapy comes of age
2011 StandoutNature
Tyrosine Kinase Inhibitors Targeted to the Epidermal Growth Factor Receptor Subfamily
2000
Development of an Unsupervised Pixel-based Clustering Algorithm for Compartmentalization of Immunohistochemical Expression Using Automated QUantitative Analysis
2009
Targetting of the N-terminal domain of the human papillomavirus type 16 E6 oncoprotein with monomeric scFvs blocks the E6-mediated degradation of cellular p53
1999
The basics of epithelial-mesenchymal transition
2009 Standout
Humanized Antibodies as Potential Therapeutic Drugs
1998
Ubiquitin Ligase Activity and Tyrosine Phosphorylation Underlie Suppression of Growth Factor Signaling by c-Cbl/Sli-1
1999 StandoutNobel
Matrix Crosslinking Forces Tumor Progression by Enhancing Integrin Signaling
2009 Standout
Identification of Cyclobutane Pyrimidine Dimer-Responsive Genes Using UVB-Irradiated Human Keratinocytes Transfected with In Vitro-Synthesized Photolyase mRNA
2015 StandoutNobel
New functions for the matrix metalloproteinases in cancer progression
2002 Standout
Engineered Nanoparticles for Drug Delivery in Cancer Therapy
2014 Standout
Gene regulation by steroid hormones
1989 Standout
Recombinant Fv immunotoxins and Fv fragments as novel agents for cancer therapy and diagnosis
1998
Inhibition of Papillomavirus Protein Function in Cervical Cancer Cells by Intrabody Targeting
2005 StandoutNobel
Cell Signaling by Receptor Tyrosine Kinases
2000 Standout
Targeted tumor killing via an intracellular antibody against erbB-2.
1995
Hierarchical Assembly of Model Cell Surfaces: Synthesis of Mucin Mimetic Polymers and Their Display on Supported Bilayers
2007 StandoutNobel
The absence of introns within a human fibroblast interferon gene
1981 StandoutNobel
Hepatocytes convert to a fibroblastoid phenotype through the cooperation of TGF-β1 and Ha-Ras: steps towards invasiveness
2002
Application of recombinant DNA technology to questions of developmental biology: A review
1979
Analysis of avian leukosis virus DNA and RNA in bursal tumors: Viral gene expression is not required for maintenance of the tumor state
1981 StandoutNobel
A progesterone responsive element maps to the far upstream steroid dependent DNase hypersensitive site of chicken lysozyme chromatin.
1988
Antigenic variation in African trypanosomes by gene replacement or activation of alternate telomeres
1984 StandoutNobel
Investigations into the control of cell form and polarity: the use of morphological mutants in fission yeast
1993 StandoutNobel
HER2 (neu) Signaling Increases the Rate of Hypoxia-Inducible Factor 1α (HIF-1α) Synthesis: Novel Mechanism for HIF-1-Mediated Vascular Endothelial Growth Factor Expression
2001 StandoutNobel
Expression of cripto, a novel gene of the epidermal growth factor gene family, leads to in vitro transformation of a normal mouse mammary epithelial cell line.
1991
Integrative Analysis of Complex Cancer Genomics and Clinical Profiles Using the cBioPortal
2013 Standout
The role of ras gene expression and transforming growth factor α production in the etiology and progression of rodent and human breast cancer
1991
Pleiotropic mutations within two yeast mitochondrial cytochrome genes block mRNA processing
1979 StandoutNobel
Regulation of messenger RNA stability in eukaryotic cells
1987
Changes in hormone responsiveness of chick oviduct during primary stimulation with estrogen
1980
TGF-beta1 and Ha-Ras collaborate in modulating the phenotypic plasticity and invasiveness of epithelial tumor cells.
1996
Number and location of mouse mammary tumor virus proviral DNA in mouse DNA of normal tissue and of mammary tumors
1980
Chemoselective Approaches to Glycoprotein Assembly
2001 StandoutNobel
Exons encode functional and structural units of chicken lysozyme.
1980
Isolation of cloned DNA sequences containing ribosomal protein genes from saccharomyces cerevisiae
1979 StandoutNobel
Transcriptional Regulation in Mammalian Cells by Sequence-Specific DNA Binding Proteins
1989 StandoutScience
Multiple mRNAs are generated from the chicken lysozyme gene
1981
A catalogue of splice junction sequences
1982 Standout
Actively transcribed genes are associated with the nuclear matrix
1983 Nature
DNA sequence and genome organization of genital human papillomavirus type 6b.
1983 StandoutNobel
A single gene from yeast for both nuclear and cytoplasmic polyadenylate-binding proteins: Domain structure and expression
1986 StandoutNobel
Steroid hormone dependence of four DNase I-hypersensitive regions located within the 7000-bp 5′-flanking segment of the ovalbumin gene.
1986
G 1 Events and Regulation of Cell Proliferation
1989 StandoutScience
The structure and evolution of the two nonallelic rat preproinsulin genes
1979 StandoutNobel
Immunotoxins for targeted cancer therapy
1998
Status of Epidermal Growth Factor Receptor Antagonists in the Biology and Treatment of Cancer
2003
Regulation of messenger RNA stability in mouse erythroleukemia cells
1985
Synergistic action of the glucocorticoid receptor with transcription factors.
1988
The receptor for transepithelial transport of IgA and IgM contains multiple immunoglobulin-like domains
1984 StandoutNatureNobel
Synthesis of Lipidated Green Fluorescent Protein and Its Incorporation in Supported Lipid Bilayers
2005 StandoutNobel
Alternative sets of DNase I-hypersensitive sites characterize the various functional states of the chicken lysozyme gene
1984 Nature
Compilation and analysis of sequences upstream from the translational start site in eukaryotic mRNAs
1984 Standout
Works of Hynes Ne being referenced
Surface expression of erbB-2 protein is post-transcriptionally regulated in mammary epithelial cells by epidermal growth factor and by the culture density.
1992
Selective inhibition of tumor cell growth by a recombinant single-chain antibody-toxin specific for the erbB-2 receptor.
1992
Amplification and overexpression of the erbB-2 gene in human tumors: its involvement in tumor development, significance as a prognostic factor, and potential as a target for cancer therapy.
1993
Intracellular expression of a single-chain antibody directed to the EGFR leads to growth inhibition of tumor cells.
1996
The transformation of primary and established mouse mammary epithelial cells by p21-ras is concentration dependent.
1988
Control of cellular content of chicken egg white protein specific RNA during estrogen administration and withdrawal
1979