Citation Impact
Citing Papers
Evidence of a Role for Insulin-Like Growth Factor Binding Protein (IGFBP)-3 in Metabolic Regulation
2010
An engineered 4-1BBL fusion protein with “activity on demand”
2020
The healing myocardium sequentially mobilizes two monocyte subsets with divergent and complementary functions
2007 Standout
Tumor imaging by means of proteolytic activation of cell-penetrating peptides
2004 StandoutNobel
A split, conditionally active mimetic of IL-2 reduces the toxicity of systemic cytokine therapy
2022 StandoutNobel
Cardiac hypertrophy is inhibited by antagonism of ADAM12 processing of HB-EGF: Metalloproteinase inhibitors as a new therapy
2002
Purine nucleoside phosphorylases: properties, functions, and clinical aspects
2000
Matrix metalloproteinases and the regulation of tissue remodelling
2007 Standout
Tumor detection using 18F-labeled matrix metalloproteinase-2 inhibitor
2003
Selective inhibition of bleomycin-induced G2 cell cycle checkpoint by simaomicin α
2004 StandoutNobel
Crystal Structure of Calf Spleen Purine Nucleoside Phosphorylase with Two Full Trimers in the Asymmetric Unit: Important Implications for the Mechanism of Catalysis
2004 StandoutNobel
Endothelin antagonism with bosentan: a review of potential applications
1999
Acute Kidney Injury and Chronic Kidney Disease as Interconnected Syndromes
2014 Standout
Disruption of the myocardial extracellular matrix leads to cardiac dysfunction
2000
Nitrosative stress and pharmacological modulation of heart failure
2005
The Neurovascular Unit Coming of Age: A Journey through Neurovascular Coupling in Health and Disease
2017 Standout
ECM remodeling in hypertensive heart disease
2007
Development of Matrix Metalloproteinase Inhibitors in Cancer Therapy
2001
Cushing's syndrome
2015 Standout
Correlation of oxidative stress with activity of matrix metalloproteinase in patients with coronary artery disease Possible role for left ventricular remodelling
2003
Individual Timp Deficiencies Differentially Impact Pro-MMP-2 Activation
2006
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
Endothelin type A-antagonist improves long-term neurological recovery after cardiac arrest in rats
2000
2009 Focused Update Incorporated Into the ACC/AHA 2005 Guidelines for the Diagnosis and Management of Heart Failure in Adults
2009 Standout
Endothelial influences on cerebrovascular tone
2005
Nitric Oxide and Peroxynitrite in Health and Disease
2007 Standout
The myocardial matrix and the development and progression of ventricular remodeling
2000
Putting tumours in context
2001 Standout
ACE inhibitor and angiotensin II type 1 receptor blocker differently regulate ventricular fibrosis in hypertensive diastolic heart failure
2005
Targeted deletion of matrix metalloproteinase-9 attenuates left ventricular enlargement and collagen accumulation after experimental myocardial infarction
2000
Targeting cancer with small molecule kinase inhibitors
2008 Standout
Matrix metalloproteinase-2 mediates cytokine-induced myocardial contractile dysfunction
2003
Fibroblast growth factor signalling: from development to cancer
2010 Standout
Common and unique mechanisms regulate fibrosis in various fibroproliferative diseases
2007 Standout
Matrix metalloproteinases 2 and 9 work in concert to produce aortic aneurysms
2002 Standout
Recent advances in MMP inhibitor design
2006
Independent and additional prognostic value of aminoterminal propeptide of type III procollagen circulating levels in patients with chronic heart failure
2004
Matrix Metalloproteinases: Regulators of the Tumor Microenvironment
2010 Standout
Signaling—2000 and Beyond
2000 Standout
Effects of the dual endothelin-receptor antagonist bosentan in patients with pulmonary hypertension: a randomised placebocontrolled study
2001 Standout
Endothelin—Biology and disease
2010
Remodelling the extracellular matrix in development and disease
2014 Standout
Nonchannel drug targets in atrial fibrillation
2004
Free radicals and antioxidants in normal physiological functions and human disease
2006 Standout
Mitochondrial mitophagic mechanisms of myocardial matrix metabolism and remodelling
2011
A Simple Enantioconvergent and Chemoenzymatic Synthesis of Optically Active α‐Substituted Amides
2011 StandoutNobel
Physiology of Local Renin-Angiotensin Systems
2006 Standout
Tumor necrosis factor-alpha and myocardial remodeling in progression of heart failure: a current perspective
2002
β-Arrestin–mediated β1-adrenergic receptor transactivation of the EGFR confers cardioprotection
2007 StandoutNobel
Mechanisms for Insulin Resistance: Common Threads and Missing Links
2012 Standout
Selective Induction of Matrix Metalloproteinases and Tissue Inhibitor of Metalloproteinases in Atrial and Ventricular Myocardium in Patients With Atrial Fibrillation
2006
Crystal structure of an angiogenesis inhibitor bound to the FGF receptor tyrosine kinase domain
1998
Regulation of cardiac hypertrophy by intracellular signalling pathways
2006 Standout
The Pathobiology of Vascular Dementia
2013 Standout
Myocardial Matrix Remodeling and the Matrix Metalloproteinases: Influence on Cardiac Form and Function
2007
Interplay of matrix metalloproteinases, tissue inhibitors of metalloproteinases and their regulators in cardiac matrix remodeling
2000
Treatment with an endothelin type A receptor-antagonist after cardiac arrest and resuscitation improves cerebral hemodynamic and functional recovery in rats
2000
Biomarkers in Heart Failure
2008 Standout
New functions for the matrix metalloproteinases in cancer progression
2002 Standout
Molecular Regulation of Vascular Smooth Muscle Cell Differentiation in Development and Disease
2004 Standout
Mechanisms of thrombogenesis in atrial fibrillation: Virchow's triad revisited
2009 Standout
Click Chemistry for Drug Development and Diverse Chemical–Biology Applications
2013 Standout
ACC/AHA 2005 Guideline Update for the Diagnosis and Management of Chronic Heart Failure in the Adult
2005 Standout
Radiosensitization of p53 mutant cells by PD0166285, a novel G(2) checkpoint abrogator.
2001
New Concepts in Diastolic Dysfunction and Diastolic Heart Failure: Part II
2002
Randomized, Double-Blind, Placebo-Controlled, Pilot Trial of Infliximab, a Chimeric Monoclonal Antibody to Tumor Necrosis Factor-α, in Patients With Moderate-to-Severe Heart Failure
2003 Standout
Matrix metalloproteinases in vascular remodeling and atherogenesis: the good, the bad, and the ugly.
2002 Standout
New Concepts in Diastolic Dysfunction and Diastolic Heart Failure: Part I
2002
Myocardial Fatty Acid Metabolism in Health and Disease
2010 Standout
Part 9: Post–Cardiac Arrest Care
2010 Standout
Mitochondrial Reactive Oxygen Species (ROS) and ROS-Induced ROS Release
2014 Standout
Extracellular protease activation and unraveling of the myocardial interstitium: critical steps toward clinical applications
2004
Matrix Metalloproteinases
2002
ACC/AHA 2008 Guidelines for the Management of Adults With Congenital Heart Disease: Executive Summary
2008 Standout
Advances in the Chemistry of Tetrahydroquinolines
2011 Standout
Fiber Types in Mammalian Skeletal Muscles
2011 Standout
Inflammation and Atherosclerosis
2002 Standout
Narrative Review: Pharmacotherapy for Chronic Heart Failure: Evidence from Recent Clinical Trials
2005
Matrix Metalloproteinase Inhibition After Myocardial Infarction
2001
Development and Evaluation of Endothelin-A Receptor (Radio)Ligands for Positron Emission Tomography
2011
Fibrosis — A Common Pathway to Organ Injury and Failure
2015 Standout
Mechanisms of Diabetic Complications
2013 Standout
Matrix Metalloproteinase Inhibitors and Cancer—Trials and Tribulations
2002 StandoutScience
Imaging and Photodynamic Therapy: Mechanisms, Monitoring, and Optimization
2010 Standout
Statins Alter Smooth Muscle Cell Accumulation and Collagen Content in Established Atheroma of Watanabe Heritable Hyperlipidemic Rabbits
2001
Matrix Metalloproteinases and Tissue Inhibitors of Metalloproteinases
2003 Standout
Interleukin-1β and Tumor Necrosis Factor-α Decrease Collagen Synthesis and Increase Matrix Metalloproteinase Activity in Cardiac Fibroblasts In Vitro
2000
Design and synthesis of new chiral pyridine–phosphite ligands for the copper-catalyzed enantioselective conjugate addition of diethylzinc to acyclic enones
2009
Selective Matrix Metalloproteinase Inhibition With Developing Heart Failure
2003
Role of Extracellular Matrix in Adaptation of Tendon and Skeletal Muscle to Mechanical Loading
2004 Standout
Synthesis of radiolabeled biphenylsulfonamide matrix metalloproteinase inhibitors as new potential PET cancer imaging agents
2003
Effects of Disturbed Flow on Vascular Endothelium: Pathophysiological Basis and Clinical Perspectives
2011 Standout
Integrating mechanisms of pulmonary fibrosis
2011 Standout
Works of Hussein Hallak being referenced
Epidermal growth factor–induced activation of the insulin-like growth factor I receptor in rat hepatocytes
2002
Prevention of subarachnoid hemorrhage—induced cerebral vasospasm by oral administration of endothelin receptor antagonists
1996
Targeting Attenuated Interferon-α to Myeloma Cells with a CD38 Antibody Induces Potent Tumor Regression with Reduced Off-Target Activity
2016
Endothelin Receptor Antagonist Increases Cerebral Perfusion and Reduces Ischaemic Damage in Feline Focal Cerebral Ischaemia
1996
Pharmacokinetics/Pharmacodynamics of CI-1000, a Purine Nucleoside Phosphorylase (PNP) Inhibitor, in Rats and Monkeys
1995
Structure−Activity Relationships in a Series of Orally Active γ-Hydroxy Butenolide Endothelin Antagonists
1997
Matrix Metalloproteinase Inhibition Attenuates Left Ventricular Remodeling and Dysfunction in a Rat Model of Progressive Heart Failure
2001
Matrix Metalloproteinase Inhibition During the Development of Congestive Heart Failure
1999
In Vitro Pharmacological Characterization of PD 166285, a New Nanomolar Potent and Broadly Active Protein Tyrosine Kinase Inhibitor
1997
Angiotensin-Converting Enzyme and Matrix Metalloproteinase Inhibition with Developing Heart Failure: Comparative Effects on Left Ventricular Function and Geometry
1999
Structure−Activity Relationships and Pharmacokinetic Analysis for a Series of Potent, Systemically Available Biphenylsulfonamide Matrix Metalloproteinase Inhibitors
2000
Hypercholesterolemia Causes Mechanical Weakening of Rabbit Atheroma
2000