Citation Impact
Citing Papers
The Hepatitis C Virus NS3 Protein: A Model RNA Helicase and Potential Drug Target
2007
Complete Replication of Hepatitis C Virus in Cell Culture
2005 StandoutScienceNobel
Topological control of cytokine receptor signaling induces differential effects in hematopoiesis
2019 StandoutScienceNobel
Multicolor Super-Resolution Imaging with Photo-Switchable Fluorescent Probes
2007 StandoutScience
A drug-controllable tag for visualizing newly synthesized proteins in cells and whole animals
2008 StandoutNobel
Structural inference of native and partially folded RNA by high-throughput contact mapping
2008 StandoutNobel
Evidence for a functional RNA element in the hepatitis C virus core gene
2007 StandoutNobel
Proteomics of HCV virions reveals an essential role for the nucleoporin Nup98 in virus morphogenesis
2016 StandoutNobel
The hepatitis C virus NS3 protein: a model RNA helicase and potential drug target.
2007
Three conformational snapshots of the hepatitis C virus NS3 helicase reveal a ratchet translocation mechanism
2009 StandoutNobel
NS3 Helicase from the Hepatitis C Virus Can Function as a Monomer or Oligomer Depending on Enzyme and Substrate Concentrations
2008
Receptors for interleukin-13 and interleukin-4 are complex and share a novel component that functions in signal transduction.
1993
Mechanical Devices of the Spliceosome: Motors, Clocks, Springs, and Things
1998
Hepatitis C virus NS3 RNA helicase domain with a bound oligonucleotide: the crystal structure provides insights into the mode of unwinding
1998
The group II intron ribonucleoprotein precursor is a large, loosely packed structure
2010 StandoutNobel
Cation–π interactions in ligand recognition and catalysis
2002
ATP Binding Modulates the Nucleic Acid Affinity of Hepatitis C Virus Helicase
2003
The Nonstructural Protein 3 Protease/Helicase Requires an Intact Protease Domain to Unwind Duplex RNA Efficiently
2004
The Helicase from Hepatitis C Virus Is Active as an Oligomer
1999
Ultrahigh and High Resolution Structures and Mutational Analysis of Monomeric Streptococcus pyogenes SpeB Reveal a Functional Role for the Glycine-rich C-terminal Loop
2012
Claudins in occluding junctions of humans and flies
2006
RecA-like motor ATPases—lessons from structures
2004
A Common Core RNP Structure Shared between the Small Nucleoar Box C/D RNPs and the Spliceosomal U4 snRNP
2000 StandoutNobel
Quaternary Polymorphism of Replicative Helicase G40P: Structural Mapping and Domain Rearrangement
2006
euHCVdb: the European hepatitis C virus database
2006 StandoutNobel
Unravelling hepatitis C virus replication from genome to function
2005 StandoutNatureNobel
A putative cell signal encoded by the folded gastrulation gene coordinates cell shape changes during Drosophila gastrulation
1994 StandoutNobel
Unconventional miR-122 binding stabilizes the HCV genome by forming a trimolecular RNA structure
2013 StandoutNobel
Two Novel Conserved Motifs in the Hepatitis C Virus NS3 Protein Critical for Helicase Action
2003
The cellular basis of epithelial morphogenesis. A review
1988
Molecular virology of hepatitis C virus.
1997
RNA translocation and unwinding mechanism of HCV NS3 helicase and its coordination by ATP
2006 Nature
CRISPR-Cas9 Circular Permutants as Programmable Scaffolds for Genome Modification
2019 StandoutNobel
Approaching a new era for hepatitis C virus therapy: inhibitors of the NS3-4A serine protease and the NS5B RNA-dependent RNA polymerase
2003
Molecular views of viral polyprotein processing revealed by the crystal structure of the hepatitis C virus bifunctional protease–helicase
1999
Product Release Is the Major Contributor tok cat for the Hepatitis C Virus Helicase-catalyzed Strand Separation of Short Duplex DNA
1998
The NS3/4A proteinase of the hepatitis C virus: unravelling structure and function of an unusual enzyme and a prime target for antiviral therapy
1999
A three-dimensional view of the molecular machinery of RNA interference
2008 StandoutNatureNobel
Melanomas acquire resistance to B-RAF(V600E) inhibition by RTK or N-RAS upregulation
2010 StandoutNature
The Primary Binding Subunit of the Human Interleukin-4 Receptor Is Also a Component of the Interleukin-13 Receptor
1995
Mechanistic Basis of 5′-3′ Translocation in SF1B Helicases
2009
Internal Processing of Hepatitis C Virus NS3 Protein
1999
The hepatitis C viral NS3 protein is a processive DNA helicase with cofactor enhanced RNA unwinding
2002
Structure and Function of the Hepatitis C Virus NS3-NS4A Serine Proteinase
2000
Structure of the human M2 muscarinic acetylcholine receptor bound to an antagonist
2012 StandoutNatureNobel
Determinants for Membrane Association of the Hepatitis C Virus RNA-dependent RNA Polymerase
2001 StandoutNobel
Construction, expression, and characterization of a novel fully activated recombinant single‐chain hepatitis C virus protease
1998
Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus
2005 StandoutNature
Escherichia coli DNA Helicase II Is Active as a Monomer
1999
DEAD-box proteins: the driving forces behind RNA metabolism
2004
The Serine Protease Domain of Hepatitis C Viral NS3 Activates RNA Helicase Activity by Promoting the Binding of RNA Substrate
2007
NMR structure of the N-terminal domain of E. coli DnaB helicase: implications for structure rearrangements in the helicase hexamer
1999
A ribonuclease zymogen activated by the NS3 protease of the hepatitis C virus
2006
RNA helicases — one fold for many functions
2007
Crystal Structure of the Helicase Domain from the Replicative Helicase-Primase of Bacteriophage T7
1999
Crystal structure of the RNA-dependent RNA polymerase of hepatitis C virus
1999
A novel recombinant single‐chain hepatitis C virus ns3‐ns4a protein with improved helicase activity
1999
Crystal Structure of RNA Helicase from Genotype 1b Hepatitis C Virus
1998
Hepatitis C Virus Entry
2007 StandoutNobel
The crystal structure of the Thermus aquaticus DnaB helicase monomer
2007 StandoutNobel
From Structure to Function: New Insights into Hepatitis C Virus RNA Replication
2005
Surrogate Wnt agonists that phenocopy canonical Wnt and β-catenin signalling
2017 StandoutNatureNobel
Structural biology of hepatitis C virus
2004
Overview of Hepatitis C Virus Genome Structure, Polyprotein Processing, and Protein Properties
2000 StandoutNobel
Convergent Evolution of Escape from Hepaciviral Antagonism in Primates
2012
Enzyme kinetics of the human norovirus protease control virus polyprotein processing order
2013
The NS5A Protein of Hepatitis C Virus Is a Zinc Metalloprotein
2004 StandoutNobel
A surprising simplicity to protein folding
2000 StandoutNatureNobel
Viral and cellular RNA helicases as antiviral targets
2005
Novel Insights into Hepatitis C Virus Replication and Persistence
2004
The case for a common ancestor: kinesin and myosin motor proteins and G proteins.
1998
The Orc4p and Orc5p Subunits of the Xenopus and Human Origin Recognition Complex Are Related to Orc1p and Cdc6p
1998 StandoutNobel
Crystal Structures of Complexes of PcrA DNA Helicase with a DNA Substrate Indicate an Inchworm Mechanism
1999
Flexibility of the Rings: Structural Asymmetry in the DnaB Hexameric Helicase
2002
Copper is required for oncogenic BRAF signalling and tumorigenesis
2014 Nature
Replication of hepatitis C virus
2007 StandoutNobel
Replication of Subgenomic Hepatitis C Virus RNAs in a Hepatoma Cell Line
1999 StandoutScience
Replication of hepatitis C virus
2000
Mechanism of action of a pestivirus antiviral compound
2000 StandoutNobel
Crystal Structure of the δ′ Subunit of the Clamp-Loader Complex of E. coli DNA Polymerase III
1997
Viral Proteomics
2007
One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA
2021 StandoutNobel
Subcellular Localization, Stability, and trans -Cleavage Competence of the Hepatitis C Virus NS3-NS4A Complex Expressed in Tetracycline-Regulated Cell Lines
2000 StandoutNobel
Characterization of nonprimate hepacivirus and construction of a functional molecular clone
2015 StandoutNobel
Chemical Deamidation: A Common Pitfall in Large-Scale N-Linked Glycoproteomic Mass Spectrometry-Based Analyses
2012
Structure-Based Mutagenesis Study of Hepatitis C Virus NS3 Helicase
1999
Biochemical and structural analysis of the NS5B RNA‐dependent RNA polymerase of the hepatitis C virus
2000
The Hepatitis C Virus NS3 Proteinase: Structure and Function of a Zinc-Containing Serine Proteinase
1998
Three proteins involved in Caenorhabditis elegans vulval invagination are similar to components of a glycosylation pathway
1999 StandoutNobel
Insights into Cytokine–Receptor Interactions from Cytokine Engineering
2014
A Novel Role for Copper in Ras/Mitogen-Activated Protein Kinase Signaling
2012
Hepatitis C Virus Subgenomic Replicon Requires an Active NS3 RNA Helicase
2005
Studying Hepatitis C Virus: Making the Best of a Bad Virus
2007 StandoutNobel
Mutations That Affect Dimer Formation and Helicase Activity of the Hepatitis C Virus Helicase
2001 StandoutNobel
Specific Interaction of Hepatitis C Virus Protease/Helicase NS3 with the 3′-Terminal Sequences of Viral Positive- and Negative-Strand RNA
2001
Freeze-frame inhibitor captures acetylcholinesterase in a unique conformation
2004 StandoutNobel
sqv mutants of Caenorhabditis elegans are defective in vulval epithelial invagination
1999 StandoutNobel
Mutational analysis of the hepatitis C virus RNA helicase
1997
The Guanine Nucleotide-Binding Switch in Three Dimensions
2001 StandoutScience
Characterization of Soluble Hepatitis C Virus RNA-Dependent RNA Polymerase Expressed in Escherichia coli
1999
MEK1 mutations confer resistance to MEK and B-RAF inhibition
2009
Conserved C-Terminal Threonine of Hepatitis C Virus NS3 Regulates Autoproteolysis and Prevents Product Inhibition
2003
Cytokine Signaling Through Nonreceptor Protein Tyrosine Kinases
1995 StandoutScience
Interleukin-13: Central Mediator of Allergic Asthma
1998 StandoutScience
Chemotherapy triggers HIF-1–dependent glutathione synthesis and copper chelation that induces the breast cancer stem cell phenotype
2015 StandoutNobel
In Vitro Selection and Characterization of Hepatitis C Virus Serine Protease Variants Resistant to an Active-Site Peptide Inhibitor
2003
Structure of Hexameric DnaB Helicase and Its Complex with a Domain of DnaG Primase
2007 StandoutScienceNobel
Enteric bacteria promote human and mouse norovirus infection of B cells
2014 StandoutScience
Sulfur(VI) Fluoride Exchange (SuFEx)-Enabled High-Throughput Medicinal Chemistry
2020 StandoutNobel
Scanning the human proteome for calmodulin-binding proteins
2005 StandoutNobel
Multiple Enzymatic Activities Associated with Recombinant NS3 Protein of Hepatitis C Virus
1998
Structure-Based Mutational Analysis of the Hepatitis C Virus NS3 Helicase
2001
Chemical Glycoproteomics
2016 StandoutNobel
Phosphorylation of hepatitis C virus nonstructural protein 5A modulates its protein interactions and viral RNA replication
2004 StandoutNobel
Characterization of the Hepatitis C Virus NS2/3 Processing Reaction by Using a Purified Precursor Protein
2001
Structure of the catalytic domain of the hepatitis C virus NS2-3 protease
2006 StandoutNatureNobel
Works of Hung V. Le being referenced
Mechanism of autoproteolysis at the NS2–NS3 junction of the hepatitis C virus polyprotein
1998
Structure of the hepatitis C virus RNA helicase domain
1997
Crystal Structures of the Pro-Inflammatory Cytokine Interleukin-23 and Its Complex with a High-Affinity Neutralizing Antibody
2008
Farnesyl Protein Transferase: Identification of K164α and Y300β as Catalytic Residues by Mutagenesis and Kinetic Studies
1999
Crystal Structures of MEK1 Binary and Ternary Complexes with Nucleotides and Inhibitors
2009
Characterization of Recombinant Human Interleukin 4 Receptor from CHO Cells: Role of N-Linked Oligosaccharides
1995
Probing the substrate specificity of hepatitis C virus NS3 serine protease by using synthetic peptides
1997
Serine Protease of Hepatitis C Virus Expressed in Insect Cells as the NS3/4A Complex
1998
The permeability properties of septate junctions in Malpighian tubules of Rhodnius
1987
Isolation and characterization of multiple variants of recombinant human interleukin 4 expressed in mammalian cells.
1988