Citation Impact
Citing Papers
Deficiency in the Repair of DNA Damage by Homologous Recombination and Sensitivity to Poly(ADP-Ribose) Polymerase Inhibition
2006
Loss of cryptochrome reduces cancer risk in p53 mutant mice
2009 StandoutNobel
PARP inhibitors: Synthetic lethality in the clinic
2017 StandoutScience
Hallmarks of Cancer: The Next Generation
2011 Standout
Telomerase gene therapy in adult and old mice delays aging and increases longevity without increasing cancer
2012
Cryptochrome, Circadian Cycle, Cell Cycle Checkpoints, and Cancer
2005 StandoutNobel
The DNA-damage response in human biology and disease
2009 StandoutNature
Getting to the end: telomerase access in yeast and humans
2003
Glioma stem cells promote radioresistance by preferential activation of the DNA damage response
2006 StandoutNature
Tipin-Replication Protein A Interaction Mediates Chk1 Phosphorylation by ATR in Response to Genotoxic Stress
2010 StandoutNobel
Chromatin Reader Brd4 Functions in Ig Class Switching as a Repair Complex Adaptor of Nonhomologous End-Joining
2014 StandoutNobel
Evolving views of telomerase and cancer
2003
Selective inhibition of the DNA-dependent protein kinase (DNA-PK) by the radiosensitizing agent caffeine
2004
Centrosome Amplification and a Defective G2–M Cell Cycle Checkpoint Induce Genetic Instability in BRCA1 Exon 11 Isoform–Deficient Cells
1999
DNA damage responses to oxidative stress
2004
DNA-PKcs and ATM co-regulate DNA double-strand break repair
2009
Regulation of Telomere Elongation by the Cyclin-Dependent Kinase CDK1
2006 StandoutNobel
Replication Protein A phosphorylation and the cellular response to DNA damage
2004
The DNA Damage Response Kinases DNA-dependent Protein Kinase (DNA-PK) and Ataxia Telangiectasia Mutated (ATM) Are Stimulated by Bulky Adduct-containing DNA
2011 StandoutNobel
ATM and Artemis promote homologous recombination of radiation-induced DNA double-strand breaks in G2
2009
DNA damage response as a candidate anti-cancer barrier in early human tumorigenesis
2005 StandoutNature
Hallmarks of aging: An expanding universe
2023 Standout
Cellular Senescence in Cancer and Aging
2007 Standout
The Human Transcription Factors
2018 Standout
AID is required for germinal center–derived lymphomagenesis
2007 StandoutNobel
γH2AX Foci Form Preferentially in Euchromatin after Ionising-Radiation
2007
Sensors and signals: a coactivator/corepressor/epigenetic code for integrating signal-dependent programs of transcriptional response
2006
Regulation of DNA double-strand break repair pathway choice
2007
Human Cancer Cells Harbor T-Stumps, a Distinct Class of Extremely Short Telomeres
2007 StandoutNobel
Oral poly(ADP-ribose) polymerase inhibitor olaparib in patients with BRCA1 or BRCA2 mutations and recurrent ovarian cancer: a proof-of-concept trial
2010 Standout
RPA2 Is a Direct Downstream Target for ATR to Regulate the S-phase Checkpoint
2006
DNA Damage, Aging, and Cancer
2009 Standout
Reactive oxygen species (ROS) as pleiotropic physiological signalling agents
2020 Standout
Multiple ATR-Chk1 Pathway Proteins Preferentially Associate with Checkpoint-Inducing DNA Substrates
2011 StandoutNobel
Senescence and tumour clearance is triggered by p53 restoration in murine liver carcinomas
2007 StandoutNature
Formation of Arabidopsis Cryptochrome 2 Photobodies in Mammalian Nuclei
2013 StandoutNobel
The DNA Damage Response: Making It Safe to Play with Knives
2010 Standout
γH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes
2006
The RING Heterodimer BRCA1-BARD1 Is a Ubiquitin Ligase Inactivated by a Breast Cancer-derived Mutation
2001
PARP-1 and Ku compete for repair of DNA double strand breaks by distinct NHEJ pathways
2006
ATR signaling can drive cells into senescence in the absence of DNA breaks
2008
Replication protein A and γ-H2AX foci assembly is triggered by cellular response to DNA double-strand breaks
2004
DNA double-strand breaks: signaling, repair and the cancer connection
2001 Standout
Programmed Cell Senescence during Mammalian Embryonic Development
2013 Standout
DNA repair dysregulation from cancer driver to therapeutic target
2012
Coupling of Human DNA Excision Repair and the DNA Damage Checkpoint in a Defined in Vitro System
2014 StandoutNobel
Applications of CRISPR technologies in research and beyond
2016 StandoutNobel
Cdc7-Dbf4 and the Human S Checkpoint Response to UVC
2007 StandoutNobel
Nucleolar protein PinX1p regulates telomerase by sequestering its protein catalytic subunit in an inactive complex lacking telomerase RNA
2004 StandoutNobel
H2AX Prevents DNA Breaks from Progressing to Chromosome Breaks and Translocations
2006
Differential impact of diverse anticancer chemotherapeutics on the Cdc25A-degradation checkpoint pathway
2004
The DNA damage response: putting checkpoints in perspective
2000 StandoutNature
The neurological phenotype of ataxia-telangiectasia: Solving a persistent puzzle
2008
Regulation of chromatin structure by site-specific histone H3 methyltransferases
2000 StandoutNature
Activation of the DNA damage checkpoint and genomic instability in human precancerous lesions
2005 StandoutNature
Alternative end-joining mechanisms: a historical perspective
2013
PML nuclear bodies: dynamic sensors of DNA damage and cellular stress
2004
The Hallmarks of Aging
2013 Standout
Engineering domain fusion chimeras from I-OnuI family LAGLIDADG homing endonucleases
2012 StandoutNobel
The role of the DNA double-strand break response network in meiosis
2004
Ku interacts with telomerase RNA to promote telomere addition at native and broken chromosome ends
2003
Inhibition of Poly(ADP-Ribose) Polymerase in Tumors from BRCA Mutation Carriers
2009 Standout
The p53 pathway: positive and negative feedback loops
2005 Standout
Actions of human telomerase beyond telomeres
2008
Mechanisms of DNA double strand break repair and chromosome aberration formation
2004
The molecular basis of ATM-dependent dimerization of the Mdc1 DNA damage checkpoint mediator
2012 StandoutNobel
DNA damage in telomeres and mitochondria during cellular senescence: is there a connection?
2007
Structure of a BRCA1-BARD1 heterodimeric RING-RING complex.
2001
Nbs1 is required for ATR‐dependent phosphorylation events
2004
Tethering DNA Damage Checkpoint Mediator Proteins Topoisomerase IIβ-binding Protein 1 (TopBP1) and Claspin to DNA Activates Ataxia-Telangiectasia Mutated and RAD3-related (ATR) Phosphorylation of Checkpoint Kinase 1 (Chk1)
2011 StandoutNobel
Trex1 Exonuclease Degrades ssDNA to Prevent Chronic Checkpoint Activation and Autoimmune Disease
2007 StandoutNobel
Redox Control of the Cell Cycle in Health and Disease
2009
Carcinogenesis and Reactive Oxygen Species Signaling: Interaction of the NADPH Oxidase NOX1–5 and Superoxide Dismutase 1–3 Signal Transduction Pathways
2018
Photothermal therapy and photoacoustic imaging via nanotheranostics in fighting cancer
2018 Standout
AID-deficient Bcl-xL transgenic mice develop delayed atypical plasma cell tumors with unusual Ig/Myc chromosomal rearrangements
2007 StandoutNobel
The Circadian Gene Per1 Plays an Important Role in Cell Growth and DNA Damage Control in Human Cancer Cells
2006
Constitutive Expression of Tert in Thymocytes Leads to Increased Incidence and Dissemination of T-Cell Lymphoma in Lck-Tert Mice
2004
Selective utilization of nonhomologous end-joining and homologous recombination DNA repair pathways during nervous system development
2006
Physical Interaction between Replication Protein A (RPA) and MRN: Involvement of RPA2 Phosphorylation and the N-Terminus of RPA1
2009
H2AX phosphorylation within the G 1 phase after UV irradiation depends on nucleotide excision repair and not DNA double-strand breaks
2006
Kinase-Independent Functions of TEL1 in Telomere Maintenance
2009 StandoutNobel
In Vitro Analysis of the Role of Replication Protein A (RPA) and RPA Phosphorylation in ATR-mediated Checkpoint Signaling
2012 StandoutNobel
megaTALs: a rare-cleaving nuclease architecture for therapeutic genome engineering
2013 StandoutNobel
Regulation of the Nrf2 antioxidant pathway by microRNAs: New players in micromanaging redox homeostasis
2013
Differential regulation of S-region hypermutation and class-switch recombination by noncanonical functions of uracil DNA glycosylase
2014 StandoutNobel
53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage.
2003
Pathways of DNA Double-Strand Break Repair during the Mammalian Cell Cycle
2003
Simultaneous precise editing of multiple genes in human cells
2019 StandoutNobel
Circadian Clock, Cancer, and Chemotherapy
2014 StandoutNobel
HdmX stimulates Hdm2-mediated ubiquitination and degradation of p53
2003 StandoutNobel
Reactive oxygen species generating systems meeting challenges of photodynamic cancer therapy
2016 Standout
Cisplatin Sensitizes Cancer Cells to Ionizing Radiation via Inhibition of Nonhomologous End Joining
2005
Recruitment of DNA Damage Checkpoint Proteins to Damage in Transcribed and Nontranscribed Sequences
2005 StandoutNobel
Works of Huichen Wang being referenced
MicroRNA-21 Modulates the Levels of Reactive Oxygen Species by Targeting SOD3 and TNF α
2012
Biochemical evidence for Ku-independent backup pathways of NHEJ
2020
DNA damage checkpoint control in cells exposed to ionizing radiation
2003
Caffeine inhibits homology-directed repair of I-SceI-induced DNA double-strand breaks
2004
Efficient rejoining of radiation-induced DNA double-strand breaks in vertebrate cells deficient in genes of the RAD52 epistasis group
2001
Caffeine Could Not Efficiently Sensitize Homologous Recombination Repair-Deficient Cells to Ionizing Radiation-Induced Killing
2003
BRCA1 proteins are transported to the nucleus in the absence of serum and splice variants BRCA1a, BRCA1b are tyrosine phosphoproteins that associate with E2F, cyclins and cyclin dependent kinases
1997
Complex H2AX phosphorylation patterns by multiple kinases including ATM and DNA‐PK in human cells exposed to ionizing radiation and treated with kinase inhibitors
2004
hTERT associates with human telomeres and enhances genomic stability and DNA repair
2003
RPA facilitates rejoining of DNA double-strand breaks in an in vitro assay utilizing genomic DNA as substrate
2001
ATR Affecting Cell Radiosensitivity Is Dependent on Homologous Recombination Repair but Independent of Nonhomologous End Joining
2004
Caffeine-Induced Radiosensitization is Independent of Nonhomologous End Joining of DNA Double-Strand Breaks
2003