Citation Impact
Citing Papers
The Fbw7 tumor suppressor regulates glycogen synthase kinase 3 phosphorylation-dependent c-Myc protein degradation
2004
C2c2 is a single-component programmable RNA-guided RNA-targeting CRISPR effector
2016 StandoutScience
Human Induced Pluripotent Stem Cells Free of Vector and Transgene Sequences
2009 StandoutScience
Global analysis of protein folding using massively parallel design, synthesis, and testing
2017 StandoutScienceNobel
A target selection of somatic hypermutations is regulated similarly between T and B cells upon activation-induced cytidine deaminase expression
2005 StandoutNobel
edgeR : a Bioconductor package for differential expression analysis of digital gene expression data
2009 Standout
De novo design of transmembrane β barrels
2021 StandoutScienceNobel
Recurrent Fusion of TMPRSS2 and ETS Transcription Factor Genes in Prostate Cancer
2005 StandoutScience
Phosphorylation Regulates c-Myc's Oncogenic Activity in the Mammary Gland
2011
Ribosomal Protein L11 Recruits miR-24/miRISC To Repress c-Myc Expression in Response to Ribosomal Stress
2011
Induced Pluripotent Stem Cell Lines Derived from Human Somatic Cells
2007 StandoutScience
Frequent Mutations of Chromatin Remodeling Gene ARID1A in Ovarian Clear Cell Carcinoma
2010 StandoutScience
Cpf1 Is a Single RNA-Guided Endonuclease of a Class 2 CRISPR-Cas System
2015 Standout
MYC on the Path to Cancer
2012 Standout
Deconstruction of the SS18-SSX Fusion Oncoprotein Complex: Insights into Disease Etiology and Therapeutics
2012 Nobel
Protein phosphatase 2A regulatory subunits and cancer
2008
AKT/PKB Signaling: Navigating Downstream
2007 Standout
Integrative genomic analyses identify MITF as a lineage survival oncogene amplified in malignant melanoma
2005 StandoutNature
Increased Survival with Enzalutamide in Prostate Cancer after Chemotherapy
2012 Standout
Helicobacter pylori infection triggers aberrant expression of activation-induced cytidine deaminase in gastric epithelium
2007 StandoutNobel
A Double S Shape Provides the Structural Basis for the Extraordinary Binding Specificity of Dscam Isoforms
2008 StandoutNobel
The Trithorax group protein Lid is a trimethyl histone H3K4 demethylase required for dMyc-induced cell growth
2007
Caenorhabditis elegans pathways that surveil and defend mitochondria
2014 StandoutNatureNobel
The ubiquitin-specific protease USP28 is required for MYC stability
2007
Regulation of Raf-1 by Direct Feedback Phosphorylation
2005
The Spliceosome: Design Principles of a Dynamic RNP Machine
2009 Standout
Induction of Pluripotent Stem Cells from Mouse Embryonic and Adult Fibroblast Cultures by Defined Factors
2006 StandoutNobel
Cancer Cell Metabolism: Warburg and Beyond
2008 Standout
Induction of Pluripotent Stem Cells from Adult Human Fibroblasts by Defined Factors
2007 StandoutNobel
New CRISPR–Cas systems from uncultivated microbes
2016 StandoutNatureNobel
Structure-Guided Reprogramming of Human cGAS Dinucleotide Linkage Specificity
2014 StandoutNobel
A ribosomal protein L23-nucleophosmin circuit coordinates Miz1 function with cell growth
2008
Gene expression profiling of the tumor microenvironment during breast cancer progression
2009
Generation of induced pluripotent stem cells without Myc from mouse and human fibroblasts
2007 StandoutNobel
Cancer Epigenetics: From Mechanism to Therapy
2012 Standout
The ground state of embryonic stem cell self-renewal
2008 StandoutNature
Role of post-translational modifications in regulating c-Myc proteolysis, transcriptional activity and biological function
2006
AID is required for germinal center–derived lymphomagenesis
2007 StandoutNobel
Structure-guided mutagenesis of a mucin-selective metalloprotease from Akkermansia muciniphila alters substrate preferences
2022 StandoutNobel
Two RNA-binding motifs in eIF3 direct HCV IRES-dependent translation
2013 StandoutNobel
The Ubiquitin Ligase HectH9 Regulates Transcriptional Activation by Myc and Is Essential for Tumor Cell Proliferation
2005
Hypoxia and the extracellular matrix: drivers of tumour metastasis
2014 StandoutNobel
Proteolytic Control of the Oncoprotein Transcription Factor Myc
2011
Massively parallel determination and modeling of endonuclease substrate specificity
2014 StandoutNobel
Evasion of the p53 tumour surveillance network by tumour-derived MYC mutants
2005 Nature
The c-Myc target gene network
2006
The prolyl isomerase PIN1: a pivotal new twist in phosphorylation signalling and disease
2007
In vivo genome editing using Staphylococcus aureus Cas9
2015 StandoutNature
WebLogo: A Sequence Logo Generator: Figure 1
2004 Standout
FBW7 ubiquitin ligase: a tumour suppressor at the crossroads of cell division, growth and differentiation
2007
MYC as a regulator of ribosome biogenesis and protein synthesis
2010
Combined Inactivation of MYC and K-Ras Oncogenes Reverses Tumorigenesis in Lung Adenocarcinomas and Lymphomas
2008
Alteration of Ceramide Synthase 6/C16-Ceramide Induces Activating Transcription Factor 6-mediated Endoplasmic Reticulum (ER) Stress and Apoptosis via Perturbation of Cellular Ca2+ and ER/Golgi Membrane Network
2011
Generation of germline-competent induced pluripotent stem cells
2007 StandoutNatureNobel
Gene Expression Analysis of Human Prostate Carcinoma during Hormonal Therapy Identifies Androgen-Responsive Genes and Mechanisms of Therapy Resistance
2004
Apoptosis and differentiation of human embryonic stem cells induced by sustained activation of c-Myc
2007
Virus-free induction of pluripotency and subsequent excision of reprogramming factors
2009 Nature
Reflecting on 25 years with MYC
2008 Standout
A Fresh Look at iPS Cells
2009 StandoutNobel
Shank-interacting protein–like 1 promotes tumorigenesis via PTEN inhibition in human tumor cells
2010
Integrase-mediated spacer acquisition during CRISPR–Cas adaptive immunity
2015 StandoutNatureNobel
AKT/PKB Signaling: Navigating the Network
2017 Standout
Transcriptional regulation and transformation by Myc proteins
2005
Ceramide targets autophagosomes to mitochondria and induces lethal mitophagy
2012
Ras, PI(3)K and mTOR signalling controls tumour cell growth
2006 StandoutNature
The Ins and Outs of MYC Regulation by Posttranslational Mechanisms
2006
Targeting the androgen receptor: improving outcomes for castration-resistant prostate cancer
2004
c-Myc suppression of miR-23a/b enhances mitochondrial glutaminase expression and glutamine metabolism
2009 StandoutNature
Serine/Threonine Phosphatases: Mechanism through Structure
2009
Myc’s broad reach
2008
Multiplexed and portable nucleic acid detection platform with Cas13, Cas12a, and Csm6
2018 StandoutScience
Systems analysis identifies an essential role for SHANK-associated RH domain-interacting protein (SHARPIN) in macrophage Toll-like receptor 2 (TLR2) responses
2011 StandoutNobel
The world according to MYC
2007
Nonimmunoglobulin target loci of activation-induced cytidine deaminase (AID) share unique features with immunoglobulin genes
2012 StandoutNobel
Lysosomal cathepsin D mediates endogenous mucin glycodomain catabolism in mammals
2022 StandoutNobel
Expression of the AID protein in normal and neoplastic B cells
2004
Programmed DNA destruction by miniature CRISPR-Cas14 enzymes
2018 StandoutScienceNobel
Recent Stem Cell Advances: Induced Pluripotent Stem Cells for Disease Modeling and Stem Cell–Based Regeneration
2010 StandoutNobel
Determination of tag density required for digital transcriptome analysis: Application to an androgen-sensitive prostate cancer model
2008
General approach to reversing ketol-acid reductoisomerase cofactor dependence from NADPH to NADH
2013 StandoutNobel
Overexpression, Amplification, and Androgen Regulation of TPD52 in Prostate Cancer
2004
Transformation of human mesenchymal stem cells increases their dependency on oxidative phosphorylation for energy production
2007
Hypoxia-inducible factor 1-dependent expression of platelet-derived growth factor B promotes lymphatic metastasis of hypoxic breast cancer cells
2012 StandoutNobel
Sudestada1, a Drosophila ribosomal prolyl-hydroxylase required for mRNA translation, cell homeostasis, and organ growth
2014 StandoutNobel
LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism
2005
The Kaposi's Sarcoma-Associated Herpesvirus LANA Protein Stabilizes and Activates c-Myc
2007
Molecular profiling of human prostate tissues: insights into gene expression patterns of prostate development during puberty
2004
The Life Cycle of C-Myc: From Synthesis to Degradation
2004
Promotion of direct reprogramming by transformation-deficient Myc
2010 StandoutNobel
Works of Hugh Arnold being referenced
CIP2A Inhibits PP2A in Human Malignancies
2007
Negative regulation of Pim-1 protein kinase levels by the B56β subunit of PP2A
2007
The Axin1 scaffold protein promotes formation of a degradation complex for c‐Myc
2009
A tumor suppressor role for PP2A-B56α through negative regulation of c-Myc and other key oncoproteins
2008
Inhibition of c‐Myc activity by ribosomal protein L11
2007
A signalling pathway controlling c-Myc degradation that impacts oncogenic transformation of human cells
2004
Protein Phosphatase 2A Regulatory Subunit B56α Associates with c-Myc and Negatively Regulates c-Myc Accumulation
2006
Direct interaction between the inhibitor 2 and ceramide via sphingolipid‐protein binding is involved in the regulation of protein phosphatase 2A activity and signaling
2008
The program of androgen-responsive genes in neoplastic prostate epithelium
2002